Data-Model_Menadione

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Plots Experiment_ESR_Danyel_2015 Model

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MENADIONE	100 mM						abs estimated conc ROS	cntrl corrected estimated conc ROS		conversion factor (for 1mM)		control samples			hours			exper 1	exper 1	exper 1
	Intensity	Intensity-cntrl	Mean	st dev	ttest		in nM	in nM		9.45E10		1049600	1049600	1049600	30		time, h	conc relat	conc relat	conc relat
0 min	1049600	0				1	11.106878306878308	0
0 min	1049600	0				1	11.106878306878308	0
0 min	1049600	0				1	11.106878306878308	0									0	0	0	0
30 minutes	2664900	1615300	1972166.6666666667	457183.7413265404	0.0017152791179242646	2.538967225609756	28.2	17.09312169312169				1072100	1072100	1072100	2		0.5	17.09312169312169	26.322751322751323	19.192592592592593
30 minutes	3537100	2487500				3.3699504573170733	37.42962962962962	26.322751322751323				1382600	1382600	1382600	4		2	82.4962962962963	44.885714285714286	37.6910052910053
30 minutes	2863300	1813700				2.7279916158536586	30.299470899470897	19.192592592592593				1134500	1134500	1134500	6		4	42.28148148148148	53.88148148148149	64.72275132275132
2h	8868000	7795900	5199800	2273844.192111676	0.01666601340386337	8.448932926829269	93.84126984126983	82.4962962962963				1550500	1550500	1550500	8		6	80.23809523809524	74.5978835978836	74.47089947089947
2h	5313800	4241700				5.062690548780488	56.23068783068783	44.885714285714286				1989700	1989700	1989700	24		8	81.87830687830689	95.23280423280424	79.11640211640211
2h	4633900	3561800				4.414919969512195	49.03597883597884	37.6910052910053									24	0	0	0
4h	5378200	3995600	5067900	1060551.993067761	0.001163051128342872	5.124047256097561	56.91216931216931	42.28148148148148
4h	6474400	5091800				6.168445121951219	68.51216931216932	53.88148148148149
4h	7498900	6116300				7.14453125	79.35343915343915	64.72275132275132
6h	8717000	7582500	7223166.666666667	311249.6318605587	2.2889890824269144E-6	8.305068597560975	92.24338624338624	80.23809523809524
6h	8184000	7049500				7.797256097560975	86.60317460317461	74.5978835978836
6h	8172000	7037500				7.785823170731708	86.47619047619047	74.47089947089947
8h	9288000	7737500	8071166.666666667	814482.8625166606	6.759688888910807E-5	8.849085365853659	98.28571428571429	81.87830687830689
8h	10550000	8999500				10.051448170731707	111.64021164021165	95.23280423280424
8h	9027000	7476500				8.600419207317072	95.52380952380952	79.11640211640211
24h	1199900	-789800	-691000	110485.70043222788	4.1204224935373086E-4	1.1431974085365855	12.697354497354498	-8.357671957671958
24h	1418000	-571700				1.3509908536585367	15.005291005291005	-6.04973544973545
24h	1278200	-711500				1.217797256097561	13.525925925925927	-7.529100529100529
Control 30’	1049600			0		1	11.106878306878308
Control 2h	1072100			0		1.021436737804878	11.344973544973545
Control 4h	1382600					1.3172637195121952	14.63068783068783
Control 6h	1134500					1.080887957317073	12.005291005291005
Control 8h	1550500					1.4772294207317074	16.40740740740741
Control 24h	1989700			0		1.895674542682927	21.055026455026454
control averge	1363166.6666666667
















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Time dalayed	Time h	# Time	[ADP]	[ATP]	[DMPO*]	[DMPO]	[Menadione]	[Menadione_internal]	[Mit-Damaged]	[Mit-Healthy]	[ROS]
0	0	0	2733190	3816810	0	1000	100000	2.06669E-35	26.7277	56.1018	0.410918
0.25	0.25	15	3332290	3217710	0.876687	969.569	97487.5	1001.64	38.5111	38.6613	5.61445
0.5	0.5	30	4837750	1712250	3.09582	938.669	95048.2	1911.38	40.7104	14.0602	10.1534
0.75	0.75	45	6048780	501221	6.29687	907.634	92679.3	2736.08	26.6871	3.26089	13.8818
1	1	60	6457670	92329.2	10.2054	876.715	90378.2	3482.11	13.7788	0.559898	17.1154
1.25	1.25	75	6533660	16342.9	14.632	846.076	88142.3	4155.39	6.78886	0.0983811	19.9771
1.5	1.5	90	6545350	4650.54	19.4194	815.851	85969.4	4761.43	3.67143	0.0282295	22.4821
1.75	1.75	105	6547810	2194.29	24.4288	786.155	83857.2	5305.32	2.32234	0.0133988	24.6417
2	2	120	6548700	1300.95	29.5403	757.088	81803.4	5791.82	1.56837	0.00795768	26.4778
2.25	2.25	135	6549190	812.731	34.654	728.726	79806.2	6225.33	1.0555	0.00497237	28.021
2.5	2.5	150	6549490	509.592	39.6888	701.129	77863.4	6609.96	0.697523	0.00311743	29.3024
2.75	2.75	165	6549680	317.676	44.5806	674.343	75973.3	6949.51	0.452413	0.00194312	30.3505
3	3	180	6549800	196.719	49.2795	648.397	74134.1	7247.51	0.288729	0.00120312	31.1912
3.25	3.25	195	6549880	121.13	53.7476	623.309	72344.1	7507.22	0.181848	7.40758E-4	31.8475
3.5	3.5	210	6549930	74.2735	57.9575	599.089	70601.7	7731.71	0.113345	4.54183E-4	32.3405
3.75	3.75	225	6549950	45.4195	61.89	575.738	68905.3	7923.79	0.0700903	2.7773E-4	32.6889
4	4	240	6549970	27.7398	65.5333	553.25	67253.4	8086.08	0.0430967	1.69621E-4	32.9096
4.25	4.25	255	6549980	16.9434	68.8812	531.614	65644.7	8221.01	0.0264008	1.03605E-4	33.0178
4.5	4.5	270	6549990	10.3625	71.9323	510.816	64077.8	8330.84	0.0161409	6.33667E-5	33.0272
4.75	4.75	285	6549990	6.35301	74.6891	490.836	62551.3	8417.66	0.00986376	3.88504E-5	32.9498
5	5	300	6550000	3.90813	77.157	471.655	61064	8483.4	0.00603309	2.39008E-5	32.7965
5.25	5.25	315	6550000	2.41445	79.3438	453.248	59614.8	8529.87	0.00369769	1.47671E-5	32.5773
5.5	5.5	330	6550000	1.4992	81.2592	435.592	58202.4	8558.73	0.00227331	9.17012E-6	32.3007
5.75	5.75	345	6550000	0.936233	82.914	418.662	56825.8	8571.51	0.00140316	5.72722E-6	31.9746
6	6	360	6550000	0.588363	84.3203	402.432	55483.9	8569.66	8.70176E-4	3.59958E-6	31.6059
6.25	6.25	375	6550000	0.372271	85.4906	386.876	54175.8	8554.49	5.4256E-4	2.27781E-6	31.2008																									50
6.5	6.5	390	6550000	0.237254	86.4378	371.968	52900.3	8527.22	3.4031E-4	1.45186E-6	30.765
6.75	6.75	405	6550000	0.152357	87.1749	357.683	51656.6	8489	2.1483E-4	9.32456E-7	30.3032
7	7	420	6550000	0.0986127	87.715	343.996	50443.8	8440.87	1.36548E-4	6.0361E-7	29.8199
7.25	7.25	435	6550000	0.0643473	88.071	330.881	49261	8383.79	8.74153E-5	3.93924E-7	29.319
7.5	7.5	450	6550000	0.0423387	88.2555	318.314	48107.3	8318.67	5.63798E-5	2.59227E-7	28.804
7.75	7.75	465	6550000	0.0280945	88.2809	306.273	46981.9	8246.33	3.66431E-5	1.72038E-7	28.2779
8	8	480	6550000	0.018803	88.159	294.734	45884.1	8167.54	2.40031E-5	1.15157E-7	27.7436
8.25	8.25	495	6550000	0.0126936	87.9013	283.675	44813.1	8083	1.58492E-5	7.77521E-8	27.2033
8.5	8.5	510	6550000	0.00864406	87.5186	273.076	43768.1	7993.37	1.055E-5	5.29549E-8	26.6593
8.75	8.75	525	6550000	0.00593785	87.0216	262.916	42748.5	7899.24	7.07994E-6	3.63814E-8	26.1134
9	9	540	6550000	0.00411448	86.42	253.176	41753.6	7801.17	4.79021E-6	2.52131E-8	25.5673
9.25	9.25	555	6550000	0.00287582	85.7232	243.836	40782.7	7699.67	3.26761E-6	1.76252E-8	25.0224
9.5	9.5	570	6550000	0.00202744	84.9402	234.879	39835.2	7595.2	2.24725E-6	1.24274E-8	24.48
9.75	9.75	585	6550000	0.00144161	84.0794	226.288	38910.4	7488.21	1.55812E-6	8.83773E-9	23.9413
10	10	600	6550000	0.00103377	83.1486	218.046	38007.8	7379.08	1.08908E-6	6.33836E-9	23.4071
10.25	10.25	615	6550000	7.47546E-4	82.1552	210.137	37126.8	7268.18	7.67354E-7	4.58405E-9	22.8784
10.5	10.5	630	6550000	5.4506E-4	81.1061	202.548	36266.8	7155.84	5.44975E-7	3.34282E-9	22.3559
10.75	10.75	645	6550000	4.00677E-4	80.0078	195.263	35427.3	7042.37	3.90088E-7	2.45765E-9	21.8401
11	11	660	6550000	2.96918E-4	78.8663	188.269	34607.7	6928.05	2.8139E-7	1.82146E-9	21.3316
11.25	11.25	675	6550000	2.21778E-4	77.6872	181.553	33807.6	6813.14	2.04536E-7	1.36067E-9	20.8308
11.5	11.5	690	6550000	1.66947E-4	76.4759	175.103	33026.5	6697.87	1.49794E-7	1.0244E-9	20.3382
11.75	11.75	705	6550000	1.26637E-4	75.237	168.906	32263.8	6582.46	1.10517E-7	7.77145E-10	19.8539
12	12	720	6550000	9.67837E-5	73.9752	162.953	31519.1	6467.1	8.21333E-8	5.94014E-10	19.3783
12.25	12.25	735	6550000	7.45152E-5	72.6945	157.231	30791.9	6351.96	6.14765E-8	4.57393E-10	18.9116
12.5	12.5	750	6550000	5.77864E-5	71.3988	151.731	30081.9	6237.21	4.63384E-8	3.54748E-10	18.4538
12.75	12.75	765	6550000	4.51317E-5	70.0917	146.444	29388.6	6122.99	3.51687E-8	2.77092E-10	18.0051
13	13	780	6550000	3.54937E-5	68.7764	141.36	28711.6	6009.44	2.68719E-8	2.17942E-10	17.5656
13.25	13.25	795	6550000	2.8104E-5	67.4559	136.47	28050.4	5896.67	2.06681E-8	1.72585E-10	17.1353
13.5	13.5	810	6550000	2.24011E-5	66.133	131.766	27404.7	5784.79	1.59994E-8	1.37578E-10	16.7142
13.75	13.75	825	6550000	1.79719E-5	64.8101	127.24	26774.1	5673.9	1.24638E-8	1.10387E-10	16.3022
14	14	840	6550000	1.45102E-5	63.4897	122.884	26158.2	5564.07	9.76955E-9	8.91335E-11	15.8994
14.25	14.25	855	6550000	1.17884E-5	62.1737	118.692	25556.8	5455.4	7.70409E-9	7.24205E-11	15.5057
14.5	14.5	870	6550000	9.63535E-6	60.8641	114.656	24969.3	5347.94	6.1112E-9	5.91992E-11	15.1209
14.75	14.75	885	6550000	7.92237E-6	59.5626	110.77	24395.5	5241.76	4.87565E-9	4.86791E-11	14.7451
15	15	900	6550000	6.55174E-6	58.2708	107.028	23835.1	5136.9	3.91181E-9	4.02608E-11	14.3781
15.25	15.25	915	6550000	5.44892E-6	56.9901	103.423	23287.7	5033.42	3.15575E-9	3.34867E-11	14.0198
15.5	15.5	930	6550000	4.55679E-6	55.7218	99.9508	22753	4931.34	2.55946E-9	2.80064E-11	13.67
15.75	15.75	945	6550000	3.83127E-6	54.467	96.6048	22230.8	4830.72	2.08669E-9	2.35492E-11	13.3287
16	16	960	6550000	3.23821E-6	53.2267	93.3803	21720.6	4731.56	1.70991E-9	1.99055E-11	12.9957
16.25	16.25	975	6550000	2.751E-6	52.0018	90.2723	21222.3	4633.9	1.40812E-9	1.69118E-11	12.6708
16.5	16.5	990	6550000	2.34878E-6	50.7931	87.2761	20735.5	4537.75	1.16519E-9	1.44402E-11	12.354
16.75	16.75	1005	6550000	2.01515E-6	49.6013	84.3873	20260	4443.14	9.687E-10	1.239E-11	12.045
17	17	1020	6550000	1.73712E-6	48.4271	81.6016	19795.4	4350.06	8.09031E-10	1.06813E-11	11.7437
17.25	17.25	1035	6550000	1.50439E-6	47.2709	78.9149	19341.7	4258.54	6.78687E-10	9.25082E-12	11.4499
17.5	17.5	1050	6550000	1.30871E-6	46.1331	76.3233	18898.4	4168.56	5.71804E-10	8.04806E-12	11.1636
17.75	17.75	1065	6550000	1.14348E-6	45.0142	73.8231	18465.3	4080.14	4.83776E-10	7.03239E-12	10.8844
18	18	1080	6550000	1.00338E-6	43.9145	71.4107	18042.2	3993.27	4.10969E-10	6.17114E-12	10.6124
18.25	18.25	1095	6550000	8.84103E-7	42.8341	69.0826	17628.9	3907.95	3.505E-10	5.43788E-12	10.3472
18.5	18.5	1110	6550000	7.8216E-7	41.7734	66.8358	17225.2	3824.18	3.00076E-10	4.81112E-12	10.0889
18.75	18.75	1125	6550000	6.94686E-7	40.7323	64.6669	16830.7	3741.94	2.57856E-10	4.27329E-12	9.83712
19	19	1140	6550000	6.19351E-7	39.7111	62.5731	16445.3	3661.23	2.22374E-10	3.81007E-12	9.5918
19.25	19.25	1155	6550000	5.54233E-7	38.7098	60.5515	16068.8	3582.04	1.92439E-10	3.40965E-12	9.35279
19.5	19.5	1170	6550000	4.97745E-7	37.7283	58.5993	15700.9	3504.35	1.67091E-10	3.06228E-12	9.11992
19.75	19.75	1185	6550000	4.48572E-7	36.7667	56.714	15341.6	3428.15	1.45549E-10	2.75987E-12	8.89305
20	20	1200	6550000	4.05621E-7	35.8249	54.893	14990.4	3353.43	1.27177E-10	2.49572E-12	8.67203
20.25	20.25	1215	6550000	3.67979E-7	34.9028	53.134	14647.4	3280.17	1.11454E-10	2.26421E-12	8.45671
20.5	20.5	1230	6550000	3.34882E-7	34.0003	51.4346	14312.3	3208.36	9.79516E-11	2.06064E-12	8.24696
20.75	20.75	1245	6550000	3.05686E-7	33.1173	49.7927	13984.8	3137.97	8.63174E-11	1.88105E-12	8.04264
21	21	1260	6550000	2.79849E-7	32.2535	48.2061	13664.9	3068.99	7.62593E-11	1.72212E-12	7.8436
21.25	21.25	1275	6550000	2.56912E-7	31.4088	46.6728	13352.3	3001.41	6.75354E-11	1.58102E-12	7.64971
21.5	21.5	1290	6550000	2.36484E-7	30.5831	45.1909	13046.9	2935.19	5.99439E-11	1.45535E-12	7.46084
21.75	21.75	1305	6550000	2.18232E-7	29.7761	43.7585	12748.5	2870.33	5.33163E-11	1.34306E-12	7.27686
22	22	1320	6550000	2.01872E-7	28.9875	42.3737	12456.9	2806.8	4.75116E-11	1.24241E-12	7.09765
22.25	22.25	1335	6550000	1.8716E-7	28.2172	41.035	12172.1	2744.58	4.24109E-11	1.15189E-12	6.92307
22.5	22.5	1350	6550000	1.73883E-7	27.4649	39.7407	11893.7	2683.65	3.79142E-11	1.0702E-12	6.75302
22.75	22.75	1365	6550000	1.61861E-7	26.7302	38.489	11621.8	2624	3.39369E-11	9.96215E-13	6.58736
23	23	1380	6550000	1.50933E-7	26.0131	37.2787	11356.1	2565.59	3.04072E-11	9.2897E-13	6.426
23.25	23.25	1395	6550000	1.40963E-7	25.3131	36.1081	11096.5	2508.42	2.72642E-11	8.67612E-13	6.2688
23.5	23.5	1410	6550000	1.31829E-7	24.63	34.9759	10842.8	2452.45	2.4456E-11	8.11397E-13	6.11567
23.75	23.75	1425	6550000	1.23426E-7	23.9635	33.8808	10594.9	2397.67	2.19386E-11	7.59676E-13	5.96649
24	24	1440	6550000	1.15661E-7	23.3134	32.8214	10352.8	2344.06	1.96742E-11	7.11877E-13	5.82117
24.25	24.25	1455	6550000	1.08452E-7	22.6793	31.7965	10116.1	2291.59	1.76308E-11	6.675E-13	5.67959
24.5	24.5	1470	6550000	1.01728E-7	22.0609	30.8048	9884.91	2240.25	1.57814E-11	6.26106E-13	5.54167
24.75	24.75	1485	6550000	9.54265E-8	21.4579	29.8454	9659	2190.01	1.4103E-11	5.87313E-13	5.40729
		1500	6550000	8.94948E-8	20.8701	28.9169	9438.26	2140.86	1.25764E-11	5.50792E-13	5.27638

(v.1.18.0)

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