Selected Cell
Cell:
Value:
README
MetaboliteCon
CopyNumber-flux
6h_CopasiData
24h_CopasiData
48h_CopasiData
ss_training_data
ss_validation_data
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| This file contains all metabolomics and proteomics data used for Parameter Estimation and Validation by Copasi | |||||||||
| 1) The tabs metaboliteCon contains steady state metabolite concentrations. In most cases absolute values were measured, in some absolute and relative data was combined which is indicated | |||||||||
| 2) The tab CopyNumber contains the protein copy number information for enzymes represented in the model | |||||||||
| 3) The tabs 6h, 24h and 48h_CopasiData contain seperated data sets for eah of these time points that can be saved as comma or tab seperated file and can be loaded by Copasi | |||||||||
| 4) The tab ss_training_data adata contain the steady state concentrations for 6h, 24h, and 48h in high Glucose concentrations (60mM at 6h) and was used as training data since it is the most complete data we have | |||||||||
| 5) The tab ss_validation_data adata contain the steady state concentrations for 6h, 24h, and 48h inlow Glucose concentrations (7mM at 6h) and was used as validation data to avoid overfitting but not as training data since reference measurements were used for CoA, AcCoA, GAP, NAD, NADH, PEP, Pi_Int | |||||||||
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| Daniels 3rd experiment and 2nd relative | ||||||||||||||||
| Metabolites | ID | 6h | 24h | 48h | SDEV 6h | SDEV 24h | SDEV 48h | Status | Note | |||||||
| AcCoA | cpd:C00024 | 0.013300675017551214 | 0.01438149983680856 | 0.016281481063073516 | 0.004140001093837813 | 0.004207884388964404 | 0.007404488644682815 | checked | ||||||||
| ACE | cpd:C00033 | 1.2389363899612698 | 0.87378 | 0.5419331025386449 | 0 | 0.03276732824018465 | 0 | checked | Uses Metabolites_cell_summary table for relative data | |||||||
| ADP | cpd:C00008 | 0.5633681860910009 | 0.5230327376535936 | 0.724075282870321 | 0.09743312185230729 | 0.20234855845515 | 0.24809174812422433 | checked | ||||||||
| ATP | cpd:C00002 | 0.00390695990562768 | 0.056103326543856406 | 0.07995499434134719 | 0.001998725790099154 | 0.01807611444029543 | 0.04681411621260141 | checked | Uses Metabolites_cell_summary table for relative data | |||||||
| CoA | cpd:C00010 | 0.004916760236965332 | 0.00423891865289675 | 0.004466344350856429 | checked | Uses relative data and assumes CoA and AcCoA, assumes they are equaly easy to detecd , risk of higher error | ||||||||||
| DGP | cpd:C00236 | 9.98442837601393E-6 | 3.0637042181931676E-4 | 5.244389422639102E-4 | 1.327573150123532E-5 | 2.725690612753342E-4 | 3.489716213552318E-4 | checked | ||||||||
| F6P | cpd:C00085 | 0.031092680419204814 | 0.05147393842919186 | 0.07493878494154056 | 0.016005928045617505 | 0.014157247302430124 | 0.04170522884473679 | checked | ||||||||
| FBP | cpd:C00354 | 0.05903448091299064 | 0.14571477370590752 | 0.23278412319474184 | 0.03113411941437734 | 0.06609562257530717 | 0.1519329883208128 | checked | ||||||||
| G6P | cpd:C00092 | 0.03172346792851546 | 0.04042098812640118 | 0.05508415358354321 | 0.030363459649508557 | 0.057084181041277104 | 0.04574342633735048 | checked | ||||||||
| GAP | cpd:C00118 | 0.027710070832295045 | 0.029329343511964423 | 0.04853032544273774 | 0.010144992749191175 | 0.024826197362146835 | 0.02554355900367113 | checked | ||||||||
| GLC_Ext | na | 60.317 | 59.603 | 54.47 | checked | Source, Todos datos growth_curve A | ||||||||||
| LAC | cpd:C00186 | 3.13806723328448 | 3.8294 | 2.7540074003758677 | 0 | 0.19459578618253778 | 0 | checked | Uses Metabolites_cell_summary table for relative data | |||||||
| NAD | cpd:C00003 | 0.13696370629346688 | 0.12081 | 0.07177657882007558 | 0 | 0.008471139238614832 | 0 | checked | No relative data in 'metabolites_cell_cummary', data from Daniel 4th and Daniel 2nd experiment in 'Metabolites_all_experiments' | |||||||
| NADH | cpd:C00004 | 0.06876397057851581 | 0.06822404934887696 | 0.05760672629036779 | 0 | 0 | 0 | checked | Note, check this | |||||||
| PEP | cpd:C00074 | 0.270800009610089 | 0.4025435907644677 | 0.48409622104048006 | 0.04810404424136271 | 0.12529983482720974 | 0.18792101490429264 | checked | ||||||||
| Pi_Int | cpd:C00009 | 9.92586205443234 | 6.946300000000001 | 5.870729669588647 | 0 | 0 | 0 | checked | Orthophosphate | |||||||
| PYR | cpd:C00022 | 1.0025528935793355 | 1.405039198852948 | 0.9284708518893254 | 0.36974023350698565 | 0.5998894777065834 | 0.4949788418882073 | checked | ||||||||
| Data source | Estimated Error accumulation | |||||||||||||||
| Average 2x GC data, NMR TOBIAS* | 1x | |||||||||||||||
| Average 2x GC data, NMR TOBIAS * Daniel relative | 2x+ | |||||||||||||||
| Average Wodke | 1x | |||||||||||||||
| Average 2x GC * O Wodke relative | 2x | |||||||||||||||
| Daniel 3rd AcCoA * relative peaks, metabolites_cell_summary for AcCoa and CoA | 1-2x+ | |||||||||||||||
| Growth cruve A data | 1x | |||||||||||||||
| Daniel 2nd relative*GC 24h | 2x | |||||||||||||||
| Tobias NMR from NAD * relative peaks Daniel 2nd for NAD and NADH | 3x+ | |||||||||||||||
| Data from old 'Metabolites all data' file manually linked | ? | |||||||||||||||
| * Daniels 4th data cannot be used, no washing bugger used |
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| CopyNumber, Order of the model | CopyNumber, Order for Index Match lookup -> Do not forget to update, not linked | ||||||||||||||||
| Enzyme | 6h | 12h | 24h | 48h | 72h | 96h | 6h | 12h | 24h | 48h | 72h | 96h | |||||
| PTS_Glc | MPN207 | 851.8335000000001 | 668.745 | 591.9764806107745 | 1476.504506 | 593.04525 | 947.6355 | FBA | MPN025 | 1354.8954999999999 | 1336.9072500000002 | 1017.6321702984367 | 1183.118523 | 1405.4985000000001 | 1160.103 | ||
| PGI | MPN250 | 971.8344999999999 | 715.29675 | 588.6934525710783 | 390.0890062 | 585.1965 | 969.962 | PRPS | MPN073 | 306.68399999999997 | 254.3205 | 254.96759673929859 | 275.111153 | 267.1095 | 330.04299999999995 | ||
| PFK | MPN302 | 510.4189999999999 | 455.05950000000007 | 289.75814954164275 | 369.2265023 | 542.7555 | 537.1555 | TKL | MPN082 | 628.11 | 604.12275 | 531.0589453039277 | 552.0652701 | 640.98825 | 696.234 | ||
| FBA | MPN025 | 1354.8954999999999 | 1336.9072500000002 | 1017.6321702984367 | 1183.118523 | 1405.4985000000001 | 1160.103 | PTS_Glc | MPN207 | 851.8335000000001 | 668.745 | 591.9764806107745 | 1476.504506 | 593.04525 | 947.6355 | ||
| TIM | MPN629 | 241.00055 | 222.68925 | 232.79035049471833 | 535.4964241 | 346.51575 | 237.45960000000002 | PGI | MPN250 | 971.8344999999999 | 715.29675 | 588.6934525710783 | 390.0890062 | 585.1965 | 969.962 | ||
| GAPDH | MPN430 | 5392.31 | 4878.6675000000005 | 4381.670988312222 | 3359.345242 | 5257.245 | 5901.945 | RPE | MPN252 | 160.43965000000003 | 134.21257500000002 | 134.30783818761577 | 241.2052082 | 136.88535000000002 | 172.02149999999997 | ||
| PGK_GMP | MPN429 | 1345.2880000000002 | 1372.077 | 1333.2829648670297 | 1071.996628 | 947.28375 | 1158.7975000000004 | PFK | MPN302 | 510.4189999999999 | 455.05950000000007 | 289.75814954164275 | 369.2265023 | 542.7555 | 537.1555 | ||
| ENO | MPN606 | 2485.315 | 2327.9025 | 1863.573255702824 | 1530.03261 | 2206.4700000000003 | 2423.715 | PYK | MPN303 | 646.4955000000001 | 656.49675 | 519.8834330156604 | 719.0703595 | 714.48825 | 763.1819999999999 | ||
| PYK | MPN303 | 646.4955000000001 | 656.49675 | 519.8834330156604 | 719.0703595 | 714.48825 | 763.1819999999999 | PDH | MPN393 | 4907.9800000000005 | 4688.67 | 3925.171378243542 | 4033.185625 | 5487.9825 | 4960.62 | ||
| LDH | MPN674 | 2067.9330000000004 | 1643.208 | 1378.3943099159542 | 1850.300929 | 2664.06 | 2170.5494999999996 | PGK_GMP | MPN429 | 1345.2880000000002 | 1372.077 | 1333.2829648670297 | 1071.996628 | 947.28375 | 1158.7975000000004 | ||
| PDH | MPN393 | 4907.9800000000005 | 4688.67 | 3925.171378243542 | 4033.185625 | 5487.9825 | 4960.62 | GAPDH | MPN430 | 5392.31 | 4878.6675000000005 | 4381.670988312222 | 3359.345242 | 5257.245 | 5901.945 | ||
| PTA_ACK | MPN533 | 2113.3595 | 1780.2224999999999 | 1545.6801029020583 | 1302.177587 | 1901.8492500000002 | 2271.9410000000003 | PTA_ACK | MPN533 | 2113.3595 | 1780.2224999999999 | 1545.6801029020583 | 1302.177587 | 1901.8492500000002 | 2271.9410000000003 | ||
| RibABC | MPN599 | 55.07215 | 75.408375 | 34.83902159514207 | 136.6803893 | 84.669375 | 75.85959500000001 | RPIA | MPN595 | 96.2241 | 72.369675 | 87.71935327756023 | 133.4389239 | 101.42474999999999 | 76.70285 | ||
| RBSK | nan | RibABC | MPN599 | 55.07215 | 75.408375 | 34.83902159514207 | 136.6803893 | 84.669375 | 75.85959500000001 | ||||||||
| PRPS | MPN073 | 306.68399999999997 | 254.3205 | 254.96759673929859 | 275.111153 | 267.1095 | 330.04299999999995 | ATPase | MPN599 | 55.07215 | 75.408375 | 34.83902159514207 | 136.6803893 | 84.669375 | 75.85959500000001 | ||
| RPIA | MPN595 | 96.2241 | 72.369675 | 87.71935327756023 | 133.4389239 | 101.42474999999999 | 76.70285 | ENO | MPN606 | 2485.315 | 2327.9025 | 1863.573255702824 | 1530.03261 | 2206.4700000000003 | 2423.715 | ||
| RPE | MPN252 | 160.43965000000003 | 134.21257500000002 | 134.30783818761577 | 241.2052082 | 136.88535000000002 | 172.02149999999997 | TIM | MPN629 | 241.00055 | 222.68925 | 232.79035049471833 | 535.4964241 | 346.51575 | 237.45960000000002 | ||
| TKL | MPN082 | 628.11 | 604.12275 | 531.0589453039277 | 552.0652701 | 640.98825 | 696.234 | LDH | MPN674 | 2067.9330000000004 | 1643.208 | 1378.3943099159542 | 1850.300929 | 2664.06 | 2170.5494999999996 | ||
| TAL | nan | RBSK | nan | ||||||||||||||
| ATPase | MPN599 | 55.07215 | 75.408375 | 34.83902159514207 | 136.6803893 | 84.669375 | 75.85959500000001 | TAL | nan | ||||||||
| 6h | 12h | 24h | 48h | 72h | 96h | Max effect of using different proteins to represent reactions for 6,24,48h time point | |||||||||||
| PGK_GMP | MPN429 | 1345.2880000000002 | 1372.077 | 1333.2829648670297 | 1071.996628 | 947.28375 | 1158.7975000000004 | ||||||||||
| MPN628 | 226.91375000000002 | 212.967825 | 217.55093272208296 | 277.980821 | 255.49230000000003 | 264.2773 | 0.16867299046746867 | 0.15521565116243477 | 0.16316936348450206 | 0.25931128302019246 | 0.2697104220356361 | 0.9202163946477883 | |||||
| PDH | MPN393 | 4907.9800000000005 | 4688.67 | 3925.171378243542 | 4033.185625 | 5487.9825 | 4960.62 | ||||||||||
| MPN392 | 4727.66 | 3900.1200000000003 | 3895.310490986035 | 2548.412197 | 5150.04 | 4613.9800000000005 | 1.0381414907163375 | 1.2021860865819511 | 1.0076658554758617 | 1.5826268724297743 | 1.0656193932474312 | 0.8381945746359881 | |||||
| MPN391 | 1582.1155 | 1572.1282500000002 | 1373.8242397908211 | 1407.217258 | 1353.429 | 1722.2835000000002 | 0.3240501643519204 | 0.412609035106612 | 0.3789460130633275 | 0.5739554577245652 | 0.23714626488337956 | 0.7853685614717348 | |||||
| MPN390 | 1531.999 | 1609.2247499999999 | 1476.1123802029106 | 1462.675089 | 1221.31275 | 1408.7080000000003 | |||||||||||
| PTA_ACK | MPN428 | 1193.8675 | 1268.7569999999998 | 1133.3402127247814 | 1077.262634 | 1297.01775 | 1124.5535000000002 | ||||||||||
| MPN533 | 2113.3595 | 1780.2224999999999 | 1545.6801029020583 | 1302.177587 | 1901.8492500000002 | 2271.9410000000003 | 1.7701792703126602 | 1.4031232931128657 | 1.363827106413111 | 1.208783769065548 | 1.4663247669509536 | 0.7704457561364523 | |||||
| RibABC | MPN258 | 282.70550000000003 | 217.278075 | 136.28812962436533 | 296.7528903 | 246.80985 | 333.79850000000005 | ||||||||||
| MPN259 | 115.79785 | 116.79727500000001 | 68.15500472390261 | 173.8955232 | 100.712325 | 147.74200000000002 | |||||||||||
| MPN260 | 101.85787499999999 | 131.7834 | 72.0226123991269 | 384.268672 | 63.2625 | 129.85059500000003 | |||||||||||
| ATPase | MPN597 | 54.544909999999994 | 42.556762500000005 | 38.47182803112161 | 93.74214804 | 57.96157500000001 | 54.21367000000001 | 0.9904263770344901 | 0.5643506109235215 | 1.104274065965334 | 0.6858492905975356 | 0.6845636335451869 | 0.51106027780357 | ||||
| MPN598 | 726.9325 | 563.0362500000001 | 513.5400109465543 | 642.8910873 | 927.6750000000002 | 773.9585000000001 | 13.19963901899599 | 7.466494935078498 | 14.740368340830845 | 4.703608839516233 | 10.95644086188188 | 0.5065338099046206 | |||||
| MPN599 | 55.07215 | 75.408375 | 34.83902159514207 | 136.6803893 | 84.669375 | 75.85959500000001 | gamma change, only occurs once | ||||||||||
| MPN600 | 431.0145 | 274.57500000000005 | 150.5625125852003 | 411.7726199 | 384.22650000000004 | 444.64630000000005 | 7.826360510711857 | 3.6411738086121073 | 4.321663057443456 | 3.012667888999055 | 4.537963106495117 | 0.4652448355309561 | |||||
| MPN601 | 38.429825 | 33.318915000000004 | 19.89443350021429 | 98.89659829 | 63.281400000000005 | 60.97805000000002 | 0.6978086927784733 | 0.4418463466425314 | 0.5710388119219846 | 0.7235609936179777 | 0.7473942024492327 | 0.6331912330917324 | |||||
| MPN602 | 130.25320000000002 | 100.748025 | 63.02063767742663 | 190.2511829 | 140.87692500000003 | 162.0479 | 2.3651373697958045 | 1.3360323041041529 | 1.8089095155936923 | 1.3919420618741243 | 1.6638474655092237 | 0.5648857107270264 | |||||
| MPN603 | 0 | 0 | 6.208187407009385 | 6.144337048 | 28.927500000000002 | 19.308625 | 0 | 0 | 0.17819637644115272 | 0.044954049951626815 | 0.34165245698341346 | ||||||
| MPN604 | 33.80233500000001 | 33.670875 | 16.828357289137177 | 120.5812888 | 37.794015 | 30.472085000000003 | 0.6137827377358611 | 0.4465137327253107 | 0.48303185676958593 | 0.8822135305404781 | 0.44637172531390484 | 0.7274784793922733 | |||||
| MPN605 | 0 | 0 | 0 | 20.7194401 | 0 | 0 | 0 | 0 | 0 | 0.15159043814634496 | 0 | ||||||
| NoxE | MPN394 | 2812.6 | 2388.83925 | 1914.4166761738581 | 1867.23124 | 1992.6270000000002 | 2366.0000000000005 | 51.07118570820278 | 31.678699481324188 | 54.950357057122496 | 13.66129588570026 | 23.534211750116263 | 0.5764966995281442 | ||||
| Cell volume (L) | Avogadro's number | Glucose upt/L 24h | |||||||||||||||
| 6.7E-17 | 6.0219999999999996E23 | 0.2215125483129287 | |||||||||||||||
| Vmax enzymes | T=24 molecules/s | vmax(mmol)/L | Flux mmol/L | C_atoms | Source | ||||||||||||
| Pts_Glc | 0.2215125483129287 | Todos datos growth_curve(with uptake rates).xls | |||||||||||||||
| PGI | 65 | 0.0016110083921144858 | 0.9483900924748582 | C6 | Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||||
| FBA | 25 | 6.196186123517253E-4 | 0.6305438332447919 | C6 | Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||||
| PFK | 200 | 0.004956948898813802 | 1.436316340292771 | C6 | Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||||
| PYK | 80 | 0.001982779559525521 | 1.0308142443194068 | C3 | Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||||
| FLUXES | 6 | 24 | 48 | 72 | 96 | 120 | 144 | Source | GLC, LAC and ACE fluxes via linear regression between different time points, not data for 6h, 24h as earliest | ||||||||
| flux(LDH) | 0.1184044541573305 | 0.388640875319521 | 1.0690820637627134 | 1.2463428429020524 | 0.31538677337019644 | -0.2706833182546647 | Todos datos growth_curve(with uptake rates).xls, linear regression on concentration measurements at arbitrary time points, Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||
| flux(PTA_ACK) | 0.3246206424685266 | 0.07665699848310692 | 0.09375232957804829 | 0.0549550394545744 | -0.005728170988020789 | 0.0011035051343715415 | Todos datos growth_curve(with uptake rates).xls, linear regression on concentration measurements at arbitrary time points, Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||
| flux(PTS_Glc) | 0.2215125483129287 | 0.23264893690131397 | 0.581417196670381 | 0.6506489411783134 | 0.15482930119108781 | 0 | Todos datos growth_curve(with uptake rates).xls, linear regression on concentration measurements at arbitrary time points, Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae. | ||||||||||
| Fluxes/copy | 6 | 24 | 48 | 72 | 96 | 120 | 144 | ||||||||||
| flux(LDH) | 8.590027781277627E-5 | 2.1004198248420218E-4 | 4.012980427478035E-4 | 5.742061366958241E-4 | |||||||||||||
| flux(PTA_ACK) | 2.1001799910540489E-4 | 5.886831354524529E-5 | 4.929535270897432E-5 | 2.4188585643101823E-5 | |||||||||||||
| flux(PTS_Glc) | 3.741914680197802E-4 | 1.5756737345257648E-4 | 9.803926372741053E-4 | 6.866025398777414E-4 |
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| Metabolites | AcCoA | ACE | ADP | ATP | CoA | DGP | F6P | FBP | G6P | GAP | GLC_Ext | LAC | NAD | NADH | PEP | Pi_Int | PYR | PTS_Glc | PGI | PFK | FBA | GAPDH | ENO | PYK | LDH | PDH | PTA_ACK | ATPase | flux(PTS_Glc) | flux(LDH) | flux(PTA_ACK) | noxE | |
| ID | cpd:C00024 | cpd:C00033 | cpd:C00008 | cpd:C00002 | cpd:C00010 | cpd:C00236 | cpd:C00085 | cpd:C00354 | cpd:C00092 | cpd:C00118 | na | cpd:C00186 | cpd:C00003 | cpd:C00004 | cpd:C00074 | cpd:C00009 | cpd:C00022 | MPN207 | MPN250 | MPN302 | MPN025 | MPN430 | MPN606 | MPN303 | MPN674 | MPN393 | MPN533 | MPN599 | flux(PTS_Glc) | flux(LDH) | flux(PTA_ACK) | MPN394 | |
| 6h | 0.013300675017551214 | 1.2389363899612698 | 0.5633681860910009 | 0.00390695990562768 | 0.004916760236965332 | 9.98442837601393E-6 | 0.031092680419204814 | 0.05903448091299064 | 0.03172346792851546 | 0.027710070832295045 | 60.317 | 3.13806723328448 | 0.13696370629346688 | 0.06876397057851581 | 0.270800009610089 | 9.92586205443234 | 851.8335000000001 | 971.8344999999999 | 510.4189999999999 | 1354.8954999999999 | 5392.31 | 2485.315 | 646.4955000000001 | 2067.9330000000004 | 4907.9800000000005 | 2113.3595 | 55.07215 | 2812.6 | |||||
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| Metabolites | AcCoA | ACE | ADP | ATP | CoA | DGP | F6P | FBP | G6P | GAP | GLC_Ext | LAC | NAD | NADH | PEP | Pi_Int | PTS_Glc | PGI | PFK | FBA | GAPDH | ENO | PYK | LDH | PDH | PTA_ACK | ATPase | flux(PTS_Glc) | flux(LDH) | flux(PTA_ACK) | noxE |
| ID | cpd:C00024 | cpd:C00033 | cpd:C00008 | cpd:C00002 | cpd:C00010 | cpd:C00236 | cpd:C00085 | cpd:C00354 | cpd:C00092 | cpd:C00118 | na | cpd:C00186 | cpd:C00003 | cpd:C00004 | cpd:C00074 | cpd:C00009 | MPN207 | MPN250 | MPN302 | MPN025 | MPN430 | MPN606 | MPN303 | MPN674 | MPN393 | MPN533 | MPN599 | flux(PTS_Glc) | flux(LDH) | flux(PTA_ACK) | MPN394 |
| 24h | 0.01438149983680856 | 0.87378 | 0.5230327376535936 | 0.056103326543856406 | 0.00423891865289675 | 3.0637042181931676E-4 | 0.05147393842919186 | 0.14571477370590752 | 0.04042098812640118 | 0.029329343511964423 | 59.603 | 3.8294 | 0.12081 | 0.06822404934887696 | 0.4025435907644677 | 6.946300000000001 | 591.9764806107745 | 588.6934525710783 | 289.75814954164275 | 1017.6321702984367 | 4381.670988312222 | 1863.573255702824 | 519.8834330156604 | 1378.3943099159542 | 3925.171378243542 | 1545.6801029020583 | 34.83902159514207 | 0.2215125483129287 | 0.1184044541573305 | 0.3246206424685266 | 1914.4166761738581 |
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| Metabolites | AcCoA | ACE | ADP | ATP | CoA | DGP | F6P | FBP | G6P | GAP | GLC_Ext | LAC | NAD | NADH | PEP | Pi_Int | PYR | PTS_Glc | PGI | PFK | FBA | GAPDH | ENO | PYK | LDH | PDH | PTA_ACK | ATPase | flux(PTS_Glc) | flux(LDH) | flux(PTA_ACK) | noxE |
| ID | cpd:C00024 | cpd:C00033 | cpd:C00008 | cpd:C00002 | cpd:C00010 | cpd:C00236 | cpd:C00085 | cpd:C00354 | cpd:C00092 | cpd:C00118 | na | cpd:C00186 | cpd:C00003 | cpd:C00004 | cpd:C00074 | cpd:C00009 | cpd:C00022 | MPN207 | MPN250 | MPN302 | MPN025 | MPN430 | MPN606 | MPN303 | MPN674 | MPN393 | MPN533 | MPN599 | flux(PTS_Glc) | flux(LDH) | flux(PTA_ACK) | MPN394 |
| 48h | 0.016281481063073516 | 0.5419331025386449 | 0.724075282870321 | 0.07995499434134719 | 0.004466344350856429 | 5.244389422639102E-4 | 0.07493878494154056 | 0.23278412319474184 | 0.05508415358354321 | 0.04853032544273774 | 54.47 | 2.7540074003758677 | 0.07177657882007558 | 0.05760672629036779 | 0.48409622104048006 | 5.870729669588647 | 1476.504506 | 390.0890062 | 369.2265023 | 1183.118523 | 3359.345242 | 1530.03261 | 719.0703595 | 1850.300929 | 4033.185625 | 1302.177587 | 136.6803893 | 0.23264893690131397 | 0.388640875319521 | 0.07665699848310692 | 1867.23124 | |
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| AcCoA | ACE_indep | ADP_indep | ATP_indep | CoA_indep | DGP | F6P | FBP | G6P | GAP | GLC_Ext_indep | LAC_indep | NAD | NADH | PEP | Pi_Int | PYR | re01_PTS_Glc_indep | re02_PGI_indep | re03_PFK_indep | re04_FBA_indep | re05_GAPDH | re06_ENO_indep | re07_PYK_indep | re08_LDH_indep | re09_PDH_indep | re10_PTA_ACK_indep | flux(re01) | flux(re08) | flux(re10) | re11_NOXE_indep | O2_indep |
| 0.013300675017551214 | 1.2389363899612698 | 0.5633681860910009 | 0.00390695990562768 | 0.004916760236965332 | 9.98442837601393E-6 | 0.031092680419204814 | 0.05903448091299064 | 0.03172346792851546 | 0.027710070832295045 | 60.317 | 3.13806723328448 | 0.13696370629346688 | 0.06876397057851581 | 0.270800009610089 | 9.92586205443234 | 1.0025528935793355 | 851.8335000000001 | 971.8344999999999 | 510.4189999999999 | 1354.8954999999999 | 5392.31 | 2485.315 | 646.4955000000001 | 2067.9330000000004 | 4907.9800000000005 | 2113.3595 | 2812.6 | 0.55 | |||
| 0.01438149983680856 | 0.87378 | 0.5230327376535936 | 0.056103326543856406 | 0.00423891865289675 | 3.0637042181931676E-4 | 0.05147393842919186 | 0.14571477370590752 | 0.04042098812640118 | 0.029329343511964423 | 59.603 | 3.8294 | 0.12081 | 0.06822404934887696 | 0.4025435907644677 | 6.946300000000001 | 1.405039198852948 | 591.9764806107745 | 588.6934525710783 | 289.75814954164275 | 1017.6321702984367 | 4381.670988312222 | 1863.573255702824 | 519.8834330156604 | 1378.3943099159542 | 3925.171378243542 | 1545.6801029020583 | 0.2215125483129287 | 0.1184044541573305 | 0.3246206424685266 | 1914.4166761738581 | 0.55 |
| 0.016281481063073516 | 0.5419331025386449 | 0.724075282870321 | 0.07995499434134719 | 0.004466344350856429 | 5.244389422639102E-4 | 0.07493878494154056 | 0.23278412319474184 | 0.05508415358354321 | 0.04853032544273774 | 54.47 | 2.7540074003758677 | 0.07177657882007558 | 0.05760672629036779 | 0.48409622104048006 | 5.870729669588647 | 0.9284708518893254 | 1476.504506 | 390.0890062 | 369.2265023 | 1183.118523 | 3359.345242 | 1530.03261 | 719.0703595 | 1850.300929 | 4033.185625 | 1302.177587 | 0.23264893690131397 | 0.388640875319521 | 0.07665699848310692 | 1867.23124 | 0.4 |
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| AcCoA | ACE_indep | ADP_indep | ATP_indep | CoA_indep | DGP | F6P | FBP | G6P | GAP | LAC_indep | NAD | NADH | PEP | Pi_Int | PYR | GLC_Ext_indep | O2_indep | re01_PTS_Glc_indep | re02_PGI_indep | re03_PFK_indep | re04_FBA_indep | re05_GAPDH | re06_ENO_indep | re07_PYK_indep | re08_LDH_indep | re09_PDH_indep | re10_PTA_ACK_indep | flux(re01) | flux(re08) | flux(re10) | re11_NOXE_indep |
| 0.01438149983680856 | 1.000523101685868 | 0.34711274285499744 | 0.04649892359497067 | 0.00423891865289675 | 3.2950855652600096E-4 | 0.046525664467330745 | 0.036535252370360094 | 0.036535252370360094 | 0.02610589300260916 | 3.8294 | 0.12081 | 0.06822404934887696 | 0.4025435907644677 | 6.946300000000001 | 1.8076263302491828 | 6.696226986748189 | 0.05525440426308392 | 851.8335000000001 | 971.8344999999999 | 510.4189999999999 | 1354.8954999999999 | 5392.31 | 2485.315 | 646.4955000000001 | 2067.9330000000004 | 4907.9800000000005 | 2113.3595 | 2812.6 | |||
| 0.01438149983680856 | 0.8354612641457676 | 0.5132582158460601 | 0.05021769399247235 | 0.00423891865289675 | 3.2269232072968865E-4 | 0.058919158131927246 | 0.04626750281687306 | 0.04626750281687306 | 0.02839005567114682 | 3.8294 | 0.12081 | 0.06822404934887696 | 0.4025435907644677 | 6.946300000000001 | 1.9629009041157106 | 5.519075347537546 | 0.05544940133070558 | 591.9764806107745 | 588.6934525710783 | 289.75814954164275 | 1017.6321702984367 | 4381.670988312222 | 1863.573255702824 | 519.8834330156604 | 1378.3943099159542 | 3925.171378243542 | 1545.6801029020583 | 1914.4166761738581 | |||
| 0.01438149983680856 | 0.6569226107274477 | 0.9315551340363857 | 0.0933882468561983 | 0.00423891865289675 | 2.6349335683458137E-4 | 0.06884648838983429 | 0.054063146801522084 | 0.054063146801522084 | 0.03535999386004328 | 3.8294 | 0.12081 | 0.06822404934887696 | 0.4025435907644677 | 6.946300000000001 | 1.030972250753765 | 4.52317175372403 | 0.0404228987501877 | 1476.504506 | 390.0890062 | 369.2265023 | 1183.118523 | 3359.345242 | 1530.03261 | 719.0703595 | 1850.300929 | 4033.185625 | 1302.177587 | 1867.23124 | |||
