External metabolite concentration times series

Selected Cell

Cell:

Value:

growth_curveA carOlina GC b AND c gene names metabolic reactions AA import rates protein copy numbers todos datos GC A

	molecules/cell.sec				Uptake in mmol/L-cells
time HOURS	lac/cell.sec	ace/cell.sec	gluc /cell.sec	Produced ATP/cell.sec	Glucose uptake mmol/L		mol/cell/s, uptake
24	4777.4239604151735	13097.90620979348	8937.66508510433	22344.162712760823	0.2215125483129287		1.484133950473513E-20	446.6666666666667
48	15681.016757030977	3092.983147408323	9386.99995221965	23467.499880549123	0.23264893690131397		1.5587477478207387E-20	4.71303294282827	Vmax lactis =3.7 (intern to extern volume ratio 0.047
72	43135.693698511786	3782.751492403874	23459.222595457835	58648.05648864459	0.581417196670381				model predicts 0.045mmol/s glucose uptake, so that about 1 mmol/L..?
96	50287.873061434104	2217.3449816929096	26252.60902156351	65631.52255390877	0.6506489411783134			6.7E-17	Cell Vol. in L
120	12725.334858557968	-231.12222865503858	6247.106314951465	15617.765787378661	0.15482930119108781			6.022140857*10^23	Avogadro's number
144	-10921.6243554167	44.52460768395325	0	-13596.374684665934	0

t0 (h)	lac/cell.sec	ace/cell.sec	gluc /cell.sec	Produced ATP/cell.sec	dpH
18.25	0	5961.797483954494	2980.898741977247	10433.145596920365	0.04369461514422124
26.75	6238.824116290289	5863.193146159066	6051.008631224677	21178.530209286368	0.033569603109482316
40.25	8652.527379030491	5202.479699266616	6927.5035391485535	24246.26238701994	0.024081764061146593
50.25	11004.975569194396	3707.633784392389	7356.304676793392	25747.066368776872	0.04676281607554689
65.5	19493.510593138897	3177.700212519589	11335.605402829244	39674.618909902354	0.062306606109505225
77.25	34736.11694952898	4005.175462729206	19370.64620612909	67797.26172145182	0.12252135998098801
90	52918.3215048531	3753.909505042157	28336.11550494763	99176.4042673167	0.19176946261276306
101	36488.85817012686	2442.7132731848797	19465.78572165587	68130.25002579554	0.45927144532222464
120.25	29333.505148681335	1875.7393658423262	15604.622257261832	54616.17790041641	0.8618702078475984
142.75	12504.92654629627	902.6769423173403	6703.801744306806	23463.306105073818	0.9664560821712032


	Correlation acetate export intracellular
	TIME h	Lactate	Acetate	pH	con. H+	corLac/H
	0	4.7315E-5	5.299E-6	7.9064	1.2405092300422253E-8	3814.1594479220003
	16.839	0.52636	1.3715	7.8784	1.3231223331133686E-8	3.9781657888084345E7
	30.387	0.98531	1.8481	7.8291	1.48217676203944E-8	6.647722628198791E7
	38.129	1.3769	2.3426	7.805	1.5667510701081492E-8	8.788249941357665E7
	48.968	5.6969	3.6089	7.7583	1.7446165981330123E-8	3.26541659989736E8
	57.484	9.4358	3.7477	7.6959	2.014187980393203E-8	4.6846670180992615E8
	68.323	20.834	4.6963	7.5734	2.6705456121918948E-8	7.80140204491776E8
	76.065	34.897	5.551	7.3817	4.152407817569982E-8	8.404039664009198E8
	110.9	82.097	7.238	6.9224	1.19563879998812E-7	6.866371349007386E8
	129.48	80.202	7.3275	6.0605	8.699614330652667E-7	9.219029367475769E7
	144.19	83.697	7.6564	5.0941	8.051930173083075E-6	1.0394650500049297E7

growth CURVE b
2 biological replicates:		WT.1	WT.2
2 technical replicates:		WT.1-R1	WT.1-R2
		WT.2-R1	WT.2-R2

ug/mL Protein in 5mL					Glucose (nmol/uL=mM)			Lactate (nmol/uL=mM)			Acetate (nmol/uL=mM)
Time (h)	WT.1-R1	WT.1-R2	WT.2-R1	WT.2-R2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2
0	22.24636264931076	22.960909633202984	21.679090072891928	21.591819119453426	0	61.61898563873938	61.20286150817288	0	0.6897982831951562	0.602016479448633	0	1.290939587517829	1.154481865549625
24	60.86726996248418	69.32182035879656	60.68181715445085	63.44181998426264	24	48.35500669301099	49.538360415959076	24	8.426452892884383	8.212929682021747	24	9.651754760511832	9.42412243373152
48	84.23454485373064	78.35454447919672	80.81999849406155	77.14363602291454	48	38.51105157862404	36.75552814501315	48	13.802491353712048	15.290035210965227	48	16.935801928362025	16.801179895078505
72	78.43090778264131	79.65272714007985	90.49636174548756	88.65272505933586	72	28.706110765859584	26.898568909329462	72	38.39135739535901	37.17875503824693	72	21.80665395494053	22.394094394216985
96	77.11090982177042	78.11454366770657	72.79090821959757	73.77272676554593	96	25.28608499678586	24.15474582129244	96	43.42628840205078	52.217654509093215	96	16.776703742007317	19.652710540667055



growth CURVE C
ug/mL Protein in 5mL					Glucose (nmol/uL=mM)			Lactate (nmol/uL=mM)			Acetate (nmol/uL=mM)
Time (h)	WT.1-R1	WT.1-R2	WT.2-R1	WT.2-R2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2
0	7.639794133034185	7.678052148059931	8.084317692951288	8.472365290576326	0	47.52275843187799	49.33029835067584	0	0.9606024429530147	0.9003475342951671	0	1.00701013305017	0.9653998521854972
24	37.09636265451257	37.59817957748065	30.6054526012594	40.32545620614831	24	50.162550487273386	48.120936385134264	24	2.7682503933563987	2.6848204667018436	24	8.251078338054835	7.458034018579504
48	69.725451576493	84.5945454714515	70.32545360521837	78.53999668771569	48	41.09883102429704	39.109233407344874	48	14.503680158743649	19.47342955233663	48	15.314218566677482	16.287170042610267
72	80.55818178306926	76.30363258318468	94.07453851136293	88.53272405407645	72	28.394019605666976	30.6436918976248	72	23.284427119093518	33.2110487756053	72	21.659794604976653	21.574126701488073
96	78.11454306819222	84.50727126685055	74.32909109245647	81.11454670949415	96	19.746424273257137	21.866059227712135	96	36.612946741060206	32.891779047927606	96	24.08910317569411	25.037569380292826
144	47.21727311546152	46.65545273845846	47.1245434602824	46.633637438470664	120	18.576072733873506	18.74512437299882	120	29.595517413012537	36.63869920479326	120	16.87460683458157	20.87042111577491
192	48.13363925912164	49.26818441195922	50.713638229153375	51.308178304975684	144	15.26007799744141	16.807541303501328	144	35.89188926858808	36.80608446303138	144	16.06687919401188	18.83886029050994
240	53.89363922791047	54.41727145086635	52.04454709118063	51.308178304975684	168	16.06631995371321	15.533160669208351	168	35.351095204896204	40.321236283650684	168	15.387650673196191	22.21663688947869
					192	14.258778097183093	11.163849547330985	192	37.03785279927773	43.772008863612925	192	16.195381049244745	21.35383676471597
					216	14.869960171736109	10.38361486478652	216	35.04207331480184	42.43290377360092	216	14.757379929480598	18.643048330461596
					240	12.178153568886037	11.189856821058322	240	34.84893175547949	40.630262011096214	240	13.031774208997435	17.82307759831173

100

table S14: Alignment of gene IDs and gene names.
MPN ID	gene name
MPN001	dnaN
MPN002	xdj1
MPN003	gyrB
MPN004	gyrA
MPN005	serS
MPN006	tmk
MPN007	holB
MPN008	thdF
MPN009	yabD
MPN010	mpn010
MPN011	mpn011
MPN012	mpn012
MPN013	mpn013
MPN014	MPN014
MPN015	rimK
MPN016	rimK
MPN017	mtd1
MPN018	pmd1
MPN019	msbA
MPN020	hepA
MPN021	dnaJ
MPN022	pip
MPN023	metS
MPN024	rpoE
MPN025	tsr
MPN026	engD
MPN027	rimL
MPN028	trsB
MPN029	efp
MPN030	nusB
MPN031	mpn031
MPN032	yfkM
MPN033	upp
MPN034	polC
MPN035	mpn035
MPN036	mpn036
MPN037	mpn037
MPN038	mpn038
MPN039	mpn039
MPN040	mpn040
MPN041	mpn041
MPN042	mpn042
MPN043	glpF
MPN044	tdk
MPN045	hisS
MPN046	aspS
MPN047	pncB
MPN048	mpn048
MPN049	mpn049
MPN050	glpK
MPN051	glpD
MPN052	mpn052
MPN053	ptsH
MPN054	mpn054
MPN055	potA
MPN056	potB
MPN057	potI
MPN058	potD
MPN059	Gcp
MPN060	metX
MPN061	ffh
MPN062	deoD
MPN063	deoC
MPN064	deoA
MPN065	cdd
MPN066	cpsG
MPN067	nusG
MPN068	secE
MPN069	rpmG2
MPN070	mpn070
MPN071	yabC
MPN072	rnmV
MPN073	prs
MPN074	smpB
MPN075	ywdF
MPN076	uhpT
MPN077	uhpT
MPN078	fruA
MPN079	fruK
MPN080	ftsX
MPN081	glnQ
MPN082	tklB
MPN083	mpn083
MPN084	mpn084
MPN085	mpn085
MPN086	mpn086
MPN087	mpn087
MPN088	mpn088
MPN089	hsdS
MPN090	mpn090
MPN091	mpn091
MPN092	mpn092
MPN093	mpn093
MPN094	mpn094
MPN095	mpn095
MPN096	mpn096
MPN097	mpn097
MPN098	mpn098

100

model_ID	reaction_ID (Yus2009)	equation	gene number	enzyme (short)	EC number	pathway	reversi-bility
M001	R001/R002	D-glucose[e] + phosphoenolpyruvate[c] --> D-glucose 6-phosphate[c] + pyruvate[c]	MPN627/MPN207	PTSI/G	2.7.3.9/2.7.1.69	Glycolysis	I
M002	R003	[c]: D-glucose 6-phosphate <==> D-fructose 6-phosphate	MPN250	PGI	5.3.1.9	Glycolysis	R
M003	R004	[c]: D-fructose 6-phosphate + ATP --> ADP + D-fructose 1,6-bisphosphate + H+	MPN302	PFK	2.7.1.11	Glycolysis	I
M004	R005	[c]: D-fructose 1,6-bisphosphate <==> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate	MPN025	FBA	4.1.2.13	Glycolysis	R
M005	R006	[c]: D-glyceraldehyde 3-phosphate <==> dihydroxyacetone phosphate	MPN629	TIM	5.3.1.1	Glycolysis	R
M006	R007	[c]: NAD+ + orthophosphate + D-glyceraldehyde 3-phosphate <==> NADH + H+ + 1,3-bisphospho-D-glycerate	MPN430	GAPDH	1.2.1.12	Glycolysis	R
M007	R008	[c]: 3-phospho-D-glycerate + ATP <==> ADP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Glycolysis	R
M008	R009	[c]: 2-phospho-D-glycerate <==> 3-phospho-D-glycerate	MPN628	PGM	5.4.2.1	Glycolysis	R
M009	R010	[c]: 2-phospho-D-glycerate <==> phosphoenolpyruvate + H2O	MPN606	ENO	4.2.1.11	Glycolysis	R
M010	R011	[c]: ADP + phosphoenolpyruvate + H+ --> ATP + pyruvate	MPN303	PYK	2.7.1.40	Glycolysis	I
M011	R012	[c]: (S)-lactate + NAD+ <==> NADH + H+ + pyruvate	MPN674	LDH	1.1.1.27	Pyruvate metabolism	R
M012	R015	[c]: lipoamide + H+ + pyruvate --> S-acetyldihydrolipoamide + CO2	MPN392/MPN393	PDH-E1	1.2.4.1	Pyruvate metabolism	I
M013	R016	[c]: acetyl-CoA + dihydrolipoamide <==> S-acetyldihydrolipoamide + CoA	MPN391	PDH-E2	2.3.1.12	Pyruvate metabolism	R
M014	R017	[c]: dihydrolipoamide + NAD+ <==> lipoamide + NADH + H+	MPN390	PDH-E3	1.8.1.4	Pyruvate metabolism	R
M015	R018	[c]: acetyl-CoA + orthophosphate <==> acetyl phosphate + CoA	MPN428	PTA	2.3.1.8	Pyruvate metabolism	R
M016	R019	[c]: acetate + ATP <==> ADP + acetyl phosphate	MPN533	ACK	2.7.2.1	Pyruvate metabolism	R
M017	R020	[c]: (2) NADH + oxygen + (2) H+ <==> (2) H2O + (2) NAD+	MPN394	NOX	1.6.99.3	Pyruvate metabolism	R
M018	R190	(4) H+[e] + ADP[c] + orthophosphate[c] <==> H2O[c] + (3) H+[c] + ATP[c]	MPN597-MPN604	ATPase	3.6.3.14	Energy metabolism	R
M019	R021	D-fructose[e] + phosphoenolpyruvate[c] --> D-fructose 1-phosphate[c] + pyruvate[c]	MPN078	FRUA	2.7.1.69	Alternative sugar metabolism	I
M020	R022	[c]: D-fructose 1-phosphate + ATP --> ADP + D-fructose 1,6-bisphosphate + H+	MPN079	FRUK	2.7.1.56	Alternative sugar metabolism	I
M021	R023	[c]: D-fructose 1-phosphate --> D-glyceraldehyde + dihydroxyacetone phosphate	MPN025	FBA	4.1.2.13	Alternative sugar metabolism	I
M022	R024	[c]: glycerol + NAD+ <==> D-glyceraldehyde + NADH + H+	MPN564	ADH	1.1.1.1	Alternative sugar metabolism	R
M023	R026	D-mannose[e] + phosphoenolpyruvate[c] --> D-mannose 6-phosphate[c] + pyruvate[c]	MPN078	FRUA	2.7.1.69	Alternative sugar metabolism	I
M024	R028	[c]: D-mannose 6-phosphate <==> D-fructose 6-phosphate	?	MPI	5.3.1.8	Alternative sugar metabolism	R
M025	R029	mannitol[e] + phosphoenolpyruvate[c] --> pyruvate[c] + D-mannitol 1-phosphate[c]	MPN651/MPN653	MTLA	2.7.1.69	Alternative sugar metabolism	I
M026	R030	[c]: NAD+ + D-mannitol 1-phosphate <==> NADH + D-fructose 6-phosphate + H+	MPN652	MTLD	1.1.1.17	Alternative sugar metabolism	R
M027	R031	L-ascorbate[e] + phosphoenolpyruvate[c] + (2) H+[c] --> L-ascorbate 6-phosphate[c] + pyruvate[c]	MPN494-MPN496	PTSA	2.7.1.69	Alternative sugar metabolism	I
M028	R032	[c]: H2O + L-ascorbate 6-phosphate <==> 3-keto-L-gulonate 6-phosphate + (3) H+	MPN497	ULAG	3.1.1.-	Alternative sugar metabolism	R
M029	R033	[c]: 3-keto-L-gulonate 6-phosphate + H+ --> CO2 + L-xylulose 5-phosphate	MPN493	KGPDC	4.1.1.85	Alternative sugar metabolism	I
M030	R034	[c]: L-ribulose 5-phosphate <==> L-xylulose 5-phosphate	MPN492	ULAE	5.1.3.22	Alternative sugar metabolism	R
M031	R035	[c]: L-ribulose 5-phosphate <==> D-xylulose 5-phosphate	MPN498	ULAF	5.1.3.4	Alternative sugar metabolism	R
M032	R191	D-ribose[e] --> D-ribose[c]	MPN258-MPN260	RibABC	3.6.3.17	Pentose phosphate pathway	I
M033	R036	[c]: D-ribose + ATP --> ADP + D-ribose 5-phosphate + H+	?	RBSK	2.7.1.15	Pentose phosphate pathway	I
M034	R037	[c]: D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate <==> D-xylulose 5-phosphate + D-erythrose 4-phosphate	MPN082	TKL	2.2.1.1	Pentose phosphate pathway	R
M035	R038	[c]: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <==> D-erythrose 4-phosphate + D-fructose 6-phosphate	?	TAL	2.2.1.2	Pentose phosphate pathway	R
M036	R039	[c]: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <==> D-xylulose 5-phosphate + D-ribose 5-phosphate	MPN082	TKL	2.2.1.1	Pentose phosphate pathway	R
M037	R040	[c]: D-ribulose 5-phosphate <==> D-xylulose 5-phosphate	MPN251	RPE	5.1.3.1	Pentose phosphate pathway	R
M038	R041	[c]: D-ribose 5-phosphate <==> D-ribulose 5-phosphate	MPN595	RPIA	5.3.1.6	Pentose phosphate pathway	R
M039	R042	[c]: D-ribose 5-phosphate + ATP --> AMP + 5-phospho-alpha-D-ribose 1-diphosphate + H+	MPN073	PRPS	2.7.6.1	Pentose phosphate pathway	I
M040	R043	[c]: D-ribose 1-phosphate <==> D-ribose 5-phosphate + (2) H+	MPN066	DEOB	5.4.2.7	Pentose phosphate pathway	R
M041	R044	[c]: 2-deoxy-D-ribose 1-phosphate <==> 2-deoxy-D-ribose 5-phosphate	MPN066	DEOB	5.4.2.7	Pentose phosphate pathway	R
M042	R046	[c]: 2-deoxy-D-ribose 5-phosphate --> acetaldehyde + D-glyceraldehyde 3-phosphate	MPN063	DERA	4.1.2.4	Pentose phosphate pathway	I
M043	R047	[c]: acetaldehyde + NAD+ + CoA <==> acetyl-CoA + NADH + H+	MPN564	ADH	1.2.1.10	Alternative sugar metabolism	R
M044	R192	glycerol[c] <==> glycerol[e]	MPN043	GlpF	-	Alternative sugar metabolism	R
M045	R049	[c]: glycerol + ATP --> ADP + sn-glycerol 3-phosphate + H+	MPN050	GK	2.7.1.30	Alternative sugar metabolism	I
M046	R193	sn-glycerol 3-phosphate[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + sn-glycerol 3-phosphate[c]	MPN133-MPN136	GlyABC	-	Alternative sugar metabolism	I
M047	R186	[c]: oxygen + sn-glycerol 3-phosphate <==> H2O2 + dihydroxyacetone phosphate	MPN051	GPO	1.1.3.21	Lipid metabolism	R
M048	R051	[c]: H2O + dihydroxyacetone phosphate --> dihydroxyacetone + orthophosphate	-	-	-	Lipid metabolism	I
M049	R052	[c]: dihydroxyacetone + ATP --> ADP + dihydroxyacetone phosphate + H+	MPN547	DHAK	2.7.1.29	Lipid metabolism	I
M050	R053	[c]: ACP-R (Mpn) + sn-glycerol 3-phosphate --> 1-acyl-glycerol 3-phosphate (Mpn) + acyl carrier protein	MPN350/MPN546	GPAM	2.3.1.15	Lipid metabolism	I
M051	R054	[c]: ACP-R (Mpn) + 1-acyl-glycerol 3-phosphate (Mpn) --> phosphatidic acid (Mpn) + acyl carrier protein	MPN299	AGPAT	2.3.1.51	Lipid metabolism	I
M052	R055	[c]: phosphatidic acid (Mpn) + CTP + H+ --> CDP-diacylglycerol (Mpn) + pyrophosphate	MPN637	CDP-DG	2.7.7.41	Lipid metabolism	I
M053	R056	[c]: CDP-diacylglycerol (Mpn) + sn-glycerol 3-phosphate --> CMP + phosphatidylglycerol 3-phosphate (Mpn) + H+	MPN253	PGP	2.7.8.5	Lipid metabolism	I
M054	R057	[c]: H2O + phosphatidylglycerol 3-phosphate (Mpn) --> orthophosphate + phosphatidylglycerol (Mpn)	?	PGPB	3.1.3.27	Lipid metabolism	I
M055	R058	[c]: CDP-diacylglycerol (Mpn) + phosphatidylglycerol (Mpn) --> cardiolipin (Mpn) + CMP + H+	?	CLS	2.7.8.-	Lipid metabolism	I
M056	R059	[c]: H2O + phosphatidic acid (Mpn) --> diacylglycerol (Mpn) + orthophosphate	MPN455	PPT	3.1.3.4	Lipid metabolism	I
M057	R060	[c]: D-glucose 1-phosphate <==> D-glucose 6-phosphate	MPN066	PGM	5.4.2.2	Lipid metabolism	R
M058	R061	[c]: D-glucose 1-phosphate + UTP + H+ <==> UDP-glucose + pyrophosphate	MPN667	UGP	2.7.7.9	Lipid metabolism	R
M059	R062	[c]: UDP-glucose <==> UDP-galactose	MPN257	UGE	5.1.3.2	Lipid metabolism	R
M060	R063/R064	[c]: diacylglycerol (Mpn) + (3) UDP-galactose + (3) UDP-glucose --> glycolipid (Mpn) + (6) H+ + (6) UDP	MPN483	GTF	-	Lipid metabolism	I
M061	R178	[c]: choline + ATP --> ADP + H+ + choline phosphate	MPN532	CHK	2.7.1.32	Lipid metabolism	I
M062	R180	[c]: CTP + H+ + choline phosphate --> CDP-choline + pyrophosphate	MPN336	PCT	2.7.7.15	Lipid metabolism	I
M063	R182	[c]: sn-glycero-3-phosphocholine + H2O <==> choline + sn-glycerol 3-phosphate + H+	MPN420	GlpQ	3.1.4.46	Lipid metabolism	R
M064	R187	[c]: phosphatidylcholine + (2) H2O <==> sn-glycero-3-phosphocholine + (2) fatty acid (Mpn)	MPN445	PldB	3.1.1.5	Lipid metabolism	R
M065	R065	[c]: AMP + pyrophosphate <==> adenine + 5-phospho-alpha-D-ribose 1-diphosphate	MPN395	APRT	2.4.2.7	Nucleotide metabolism	R
M066	R066	[c]: adenosine + orthophosphate + (2) H+ <==> D-ribose 1-phosphate + adenine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M067	R067	[c]: H2O + AMP --> adenosine + orthophosphate	?	NT5	3.1.3.5	Nucleotide metabolism	I
M068	R068	[c]: AMP + ATP <==> (2) ADP	MPN185	AK	2.7.4.3	Nucleotide metabolism	R
M069	R069	[c]: ADP + reduced thioredoxin --> dADP + H2O + oxidized thioredoxin	MPN322-MPN324	RDR	1.17.4.1	Nucleotide metabolism	I
M070	R070	[c]: oxidized thioredoxin + H+ + NADPH <==> NADP+ + reduced thioredoxin	MPN240	TXNRD	1.8.1.9	Nucleotide metabolism	R
M071	R071/R084/R099/R104	[c]: (28) GTP + (25) UTP + (40) H2O + (18) CTP + (69) ATP --> (40) ADP + RNA (Mpn) + (40) orthophosphate + (40) H+ + (100) pyrophosphate	MPN516	RNAP	-	Nucleotide metabolism	I
M072	R072	[c]: H2O + pyrophosphate --> (2) orthophosphate + H+	MPN528	PPA	3.6.1.1	Nucleotide metabolism	I
M073	R073	[c]: deoxyadenosine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + adenine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M074	R074	[c]: deoxyadenosine + ATP <==> ADP + H+ + dAMP	MPN386	DAK	2.7.1.76	Nucleotide metabolism	R
M075	R075	[c]: dAMP + ATP <==> dADP + ADP	MPN185	AK	2.7.4.3	Nucleotide metabolism	R
M076	R076	[c]: phosphoenolpyruvate + dADP + H+ --> dATP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M077	R175	[c]: 3-phospho-D-glycerate + dATP <==> dADP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Nucleotide metabolism	R
M078	R077/R089/R110/R120	[c]: (20) dGTP + (140) H2O + (30) dTTP + (20) dCTP + (140) ATP + (30) dATP --> (140) ADP + DNA (Mpn) + (140) orthophosphate + (140) H+ + (100) pyrophosphate	MPN034/MPN378	DNAP	-	Nucleotide metabolism	I
M079	R078	[c]: GMP + pyrophosphate <==> 5-phospho-alpha-D-ribose 1-diphosphate + guanine	MPN672	HPRT	2.4.2.8	Nucleotide metabolism	R
M080	R079	[c]: guanosine + orthophosphate + (2) H+ <==> D-ribose 1-phosphate + guanine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M081	R080	[c]: GMP + H2O --> guanosine + orthophosphate	?	NT5	3.1.3.5	Nucleotide metabolism	I
M082	R081	[c]: GMP + ATP <==> ADP + GDP	MPN246	GUK	2.7.4.8	Nucleotide metabolism	R
M083	R082	[c]: reduced thioredoxin + GDP --> H2O + oxidized thioredoxin + dGDP	MPN322-MPN324	RDR	1.17.4.1	Nucleotide metabolism	I
M084	R083	[c]: phosphoenolpyruvate + H+ + GDP --> GTP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M085	R176	[c]: GTP + 3-phospho-D-glycerate <==> GDP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Nucleotide metabolism	R
M086	R085	[c]: deoxyguanosine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + guanine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M087	R086	[c]: deoxyguanosine + ATP <==> ADP + H+ + dGMP	MPN386	DGK	2.7.1.113	Nucleotide metabolism	R
M088	R087	[c]: ATP + dGMP <==> ADP + dGDP	MPN246	GUK	2.7.4.8	Nucleotide metabolism	R
M089	R088	[c]: phosphoenolpyruvate + dGDP + H+ --> dGTP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M090	R177	[c]: 3-phospho-D-glycerate + dGTP <==> dGDP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Nucleotide metabolism	R
M091	R090	[c]: UMP + pyrophosphate <==> uracil + 5-phospho-alpha-D-ribose 1-diphosphate	MPN033	UPRT	2.4.2.9	Nucleotide metabolism	R
M092	R091	[c]: orthophosphate + (2) H+ + uridine <==> uracil + D-ribose 1-phosphate	MPN064	UPP	2.4.2.3	Nucleotide metabolism	R
M093	R092	[c]: H2O + UMP --> orthophosphate + uridine	?	NT5	3.1.3.5	Nucleotide metabolism	I
M094	R093	[c]: ATP + uridine --> ADP + UMP + H+	MPN561	UCK	2.7.1.48	Nucleotide metabolism	I
M095	R094	[c]: UMP + ATP <==> ADP + UDP	MPN632	UMPK	2.7.4.22	Nucleotide metabolism	R
M096	R095	[c]: phosphoenolpyruvate + H+ + UDP --> UTP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M097	R096	[c]: reduced thioredoxin + UDP --> H2O + oxidized thioredoxin + dUDP	MPN322-MPN324	RDR	1.17.4.1	Nucleotide metabolism	I
M098	R097	[c]: cytidine + H2O --> NH3 + uridine	MPN065	CDA	3.5.4.5	Nucleotide metabolism	I
M099	R100	[c]: cytidine + ATP --> ADP + CMP + H+	MPN561	UCK	2.7.1.48	Nucleotide metabolism	I

aa		aa in proteome	aa in cytosol	times enrichment	import/min during exp growth	min for intracellular pool tunrover
L	Leu	2393036	25097.05592913839	95.3512637799726	1994.1966666666667	12.585045571803377
E	Glu	1672072	98709.27690427659	16.93936023481859	1393.3933333333334	70.84092807315228
A	Ala	2032737	38012.458206949574	53.47554712019039	1693.9475	22.440163114234398
V	Val	1864124	12050.334305584664	154.69479540796488	1553.4366666666667	7.75720991023215
I	Ile	1724690	17162.645565208353	100.49091752475763	1437.2416666666666	11.941377684250517
S	Ser	1515135	12566.026347110956	120.57391558377111	1262.6125	9.952401348086571
G	Gly	1588085	34936.658649543664	45.4561214891895	1323.4041666666667	26.39908467081573
D	Asp	1305481	23289.714936892153	56.053970756509706	1087.9008333333334	21.407939237928844
T	Thr	1533247	6433.410380326506	238.32569498266412	1277.7058333333334	5.035126405850986
F	Phe	1102859	39005.54349337493	28.27441694761464	919.0491666666666	42.44119347264693
R	Arg	907229	38302.24724840229	23.686051476727478	756.0241666666666	50.66272870254671
P	Pro	974850	35012.34123028322	27.843039503934204	812.375	43.09874285925
N	Asn	1473974	13655.645188364413	107.93880330575162	1228.3116666666667	11.117410636847932
M	Met	469166	12369.476786726444	37.92933267019484	390.97166666666664	31.637783096114667
Q	Gln	1179691	7692.708238618437	153.35184481296088	983.0758333333334	7.825142250252077
K	Lys	2149849	24800.00990495273	86.68742505504648	1791.5408333333332	13.842838211401489
H	His	478238	12279.469738303413	38.94614427105348	398.5316666666667	30.811779252096432
C	Cys	197940	3627.5517146154225	54.56572795433869	164.95	21.991826096486346
Y	Tyr	748700	5417.454387835065	138.20144045535696	623.9166666666666	8.682977514895256
W	Trp	211534	6470.8277604091345	32.69040806405659	176.27833333333334	36.708015319007636

sum		25522637	466890.8569169164	80.57381106984371
average					1063.4432083333334	24.35898567139502

101

102

103

104

105

106

107

108

109

110

111

112

113

114

115

116

117

118

119

120

121

122

123

124

125

126

127

128

129

130

131

132

133

134

135

136

137

138

139

140

141

142

143

144

145

146

147

148

149

150

151

152

153

154

155

156

157

158

159

160

161

162

163

164

165

166

167

168

169

170

171

172

173

174

175

176

177

178

179

180

181

182

183

184

185

186

187

188

189

190

191

192

193

194

195

196

197

198

199

200

MPN183	83.84493333228718	51.45030003812101	24.176877095774337	17.031002109671586	33.10922085	MPN098	0	0	0	0	3.34	7.7	13.6	13.6	0	0	0	0	0	2.14	0	0	0	0	7.73	2.15	0	2.38	28.8	26.4	7.25	15.71	12.9	10.6	0	8.63	10.9	12.2	13.36	4.17	26.6	0	0	9.58	0	32.8	17.25	8.79	1.32	0	0	0	0	0	24.6	23.2	8.97	5.63	27.5	20.6	13.34	11.9	0	0	0	14.5
MPN184	1.245967503577695	16.072980822086652	1.245967503577695	9.63132880446689	56.06853769	MPN099	0	0	0	0	132.69	123.13	0	0	117.51	80.7	0	0	106.64	111.09	91.05	99.06	0	0		0	93.5	90.64	0	0	61.66	48.38	76.3	77	107.15	103.73	77.7	57.3	112.3	110.38	0	0	104.47	74.05	0	0	79.21	77.68	58.43	61.02	62.2	36.2	59.79	100.46	0	0	37.3	27.17	0	0	79.55	76.38	0	0	0	0
MPN185	65.37666183127865	92.6293478603085	41.69809865270822	53.46291931494345	29.33759085	MPN100	0	0	0	0	0	0	0	0	6.62	8.26	0	0	3.27	2.97	4.91	5.21	0	0		0	3.66	3.41	0	0	0	0	4.8	8.7	6.88	7.16	4	7.8	9.27	8.29	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3.41	0	0	0	0
MPN186	66.71847512194206	32.987201457026025	54.31727158797534	11.855550608530967	20.5115907	MPN101	0	0	0	0	284.1	256.21	0	0	312.83	306.39	0	0	280.68	305.33	289.97	296.63	0	0		0	276.81	272.7	0	0	156.32	162.41	282.8	319	293.72	292.58	235.3	250.2	293.56	285.75	0	0	272.86	270.98	0	0	223.52	227.05	209.52	214.85	231.9	239.7	275.68	261.14	0	0	164.2	153.67	0	0	223.42	215.03	0	0	0	0
MPN187	48.85619752441242	47.18590020169725	49.69134624050535	45.098028510990105	24.7204008	MPN102	0	0	0	0	29.38	22.41	0	0	29.21	24.33	0	0	0	0	0	0	0	0		0	0	0	0	0	0	5.38	0	0	30.4	0	0	0	0	0	0	0	0	25.66	0	0	0	0	0	0	0	0	24.92	0	0	0	15.13	0	0	0	18.41	0	0	0	0	0
MPN189	50.60169004886273	31.22231939449432	13.00929973906712	7.868383357047377	17.40554587	MPN103	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN190	339.0478496439056	184.09837974347278	147.7389497179736	62.13320313952361	100.0267864	MPN104	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			1.99	2.33	0	0
MPN191	770.9927283866091	578.2445457684248	613.750789835133	552.8829433877843	473.754742	MPN105	66.44	67.83	71.9	73.3	61.56	37.18	72.2	72.2	31.27	32.29	66.1	67.9	45.84	61.63	64.45	66.92	76.3	72.9	50.62	67.57	73.84	75.37	62.1	60.9	51.47	41.71	39.6	34.1	34.66	40.33	42.4	39.2	54.78	52.29	53.7	52.6	36.93	33.97	55.1	41.8	42.59	52.25	36.13	49.86	44.4	43.4	42.9	63.85	60.9	60.5	24.6	26.39	63.7	64.1	45.63	49.88	64.07	62.19	64.5	64.5
MPN193	24.473179506389236	37.31273173222207	31.070297501005356	28.658447883279354	25.39535731	MPN106	80.98	92.06	86.7	98	57.32	77.67	95.2	92.8	47.52	44.78	95.9	98.2	53.36	53.95	60.02	59.07	77.4	78	55.62	68.48	61.28	61.02	78.1	91.8	63.24	54.04	68.3	55.5	57.7	56.82	63.6	59.1	53.13	53.43	69	75	50.13	48.57	57.6	63.1	59.96	53.7	67.74	65.47	63	72.2	52.38	51.86	76.3	70.8	32.48	33.3	88.2	84.8	63.15	56.39	60.53	76.71	73.1	83.2
MPN194	27.536970146453392	34.3866185264144	44.349743433237286	38.1227903478603	28.29804219	MPN107	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN195	2.183873134249807	21.838731342498072	10.61814179661809	15.66364178818011	13.55507462	MPN108	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN196	22.071652781432594	7.326982452695188	20.559895761217973	10.179164069496418	3.174689784	MPN109	44.36	45.83	49.4	50.9	42.11	28.44	31.4	33.9	22.46	51.5	37.3	32.4	50.54	30.05	54.04	62.86	46	46.3	20.36	29.71	58.06	59.44	48.9	47.7	53.2	47.63	60.4	56.7	51.5	58.59	57.6	50.2	50.78	58.88	32.5	36.2	40.32	41.06	32.7	28.6	42.24	36.5	37.26	24.66	26.5	49	47.48	29.91	36.6	39	51.46	52.53	40.8	42.9	53.02	73.48	11.7	21.72	46	44.5
MPN197	219.2013689671504	243.4821360322519	263.04164273173524	244.15660199244567	233.027917	MPN110	0	0	0	0	0	0	13.6	13.6	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	197.6			0	0	0	0
MPN199					4.770781424	MPN111	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN200	45.468094691206964	37.50933578873602	41.7097918736411	20.70751152674158	27.70827165	MPN112	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN207	284.9870985482503	482.4781584336961	404.9816670983011	404.9816670983011	474.978498	MPN113	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN208	321.9682299155821	545.8885222133651	130.7747501541111	218.62040322260592	536.613717	MPN114	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN209	30.58856319061723	31.430856999742094	160.47912869865277	159.1491911514543	131.6638156	MPN115	154.24	196.83	161.1	204.5	201.87	200.66	149.5	109.9	225.56	266.98	154.8	161	226.94	229.59	199.57	229.82	123.6	130.6	125.34	103.95	205.98	205.99	131.7	143.6	165.81	161.22	192.2	209.4	203.58	187.49	203.9	214.1	194.02	208.39	119.1	147.6	239.95	252.35	113.8	189.1	158.91	229.79	219.44	171.13	251.4	109.2	237.04	233.87	121	123.6	153.57	151.67	123.9	104.2	199.5	199.74	93.26	109.12	136	108.7
MPN210	94.74455049985598	60.090901668842974	59.96801640605197	52.71778501362973	70.04460938	MPN116	12.32	12.84	16.9	17.4	59.97	59.84	18.1	18.5	114.18	119.4	16.7	17.2	22.15	29.22	31.27	33.2	16.9	18	2.09	1.68	27.6	26.89	23.7	22.4	0	5.13	25.9	20.3	36.9	45.53	23.5	11.6	65.62	69.37	22.1	21.9	64.87	68.54	20.4	18.8	13.76	11.76	5.87	4.83	5.5	3	32.66	27.9	20.5	16.4	16.8	14.29	19.6	17.1	21.89	20.65	16.14	20.81	11.5	14.9
MPN211	73.60171108832505	53.76274341985863	64.92753034856226	59.43101984894645	54.5356902	MPN117	27.27	24.95	32.1	29.7	74.19	32.9	24.1	30.3	70.65	71.57	45.5	48.7	42.43	44.73	23.73	28.23	33.1	44.4	28.32	28.82	31.65	33.52	52.6	51.7	34.82	16.6	32.2	29.9	26.44	30.51	53.8	35.3	24.19	31.67	74	72.5	82.92	88.44	76.9	82.3	50.26	106.8	103.18	81.96	84.1	71.6	81.27	61.18	44.9	58.8	15.91	18.62	51.8	50	31.04	12.24	33.74	44.13	26.1	39.9
MPN213	63.77113162014359	40.99572739824864	19.462618087413983	30.229172761209764	34.23212258	MPN118	27.67	29.97	32.5	34.8	15.85	5.93	23.3	36.1	9.03	7.18	29.5	30.9	8.8	13.83	9.99	9.4	19.9	28.6	12.19	12	13.29	13.62	18.6	24.5	8.35	4.76	4.9	4.4	6.78	7.41	5.4	5.8	7.61	8.29	16	16	5.46	5.18	20.9	20.8	8.88	8.82	6.9	7.42	1.9	4.3	7.75	6.36	24.1	24.4	3.98	6.97	17	22.1	10.11	9.58	9.87	11.48	17.5	18.6
MPN214	5.068095309860521	23.23408931796466	33.829855329367696	21.829831151911545	7.787249716	MPN119	161.21	161.21	168.2	168.3	104.66	102.99	168.2	156.1	132.67	141.97	153.2	176.7	132.77	128.9	119.68	112.23	131.3	133.3	107.06	116.31	120.01	109.04	113.8	110.5	105.79	86.95	101	111.6	111.72	108.28	106.3	121.7	113.99	115.17	108.3	117.4	141.23	140.46	144.1	124.9	152.57	147.29	132.76	164.78	121	153.6	126.32	132.02	118.9	135.2	116.78	121.12	130.6	125.1	88.23	91.2	102.82	134.89	110.6	103.6
MPN215	313.02839682465014	184.04182152985538	209.20993376939413	103.03195985801537	115.1441139	MPN120	226.42	229.64	234.5	237.8	209.12	195.24	212.3	215.9	234.14	225.96	234.2	230.6	283.4	284.48	274.78	282.16	262.1	264	209.54	231.21	270.15	275.8	260.5	252.2	315.7	294.58	278.9	289.5	278.58	281.46	233.1	255.8	188.42	179.04	210.5	207.5	245.89	242.17	225.4	186.2	269.75	269.43	282.47	238.75	306.6	299.3	271.73	263.35	243.7	221.8	312.74	303.29	225.6	233	281.88	277.27	220.61	213.48	258.6	222.2
MPN216	162.80225041309248	236.60593751277653	74.02075658919239	100.28618621649625	197.5333972	MPN121	145.05	156.2	151.8	163.2	61.63	59.09	132.1	136.6	75.84	78.07	150	134	94.21	79.03	83.38	86.27	176.8	179.1	120.91	71.85	89.07	82.09	140.3	122.4	79.66	65.66	54.9	60.6	66.8	74.06	61.7	66.4	78.52	80.38	120.4	128.4	74.94	73.77	135.3	114.4	81.62	95.48	80.75	93.4	173.1	176.9	78.22	88.62	125.9	122.7	107.96	111.19	155.5	147.7	91.53	88.85	133.96	129.16	112.4	149
MPN217	113.46485326475346	90.25613330702667	78.90964795314297	108.8231093989887	62.92141865	MPN122	17.72	17.19	22.4	21.8	20.1	20.03	22.1	25.7	24.09	23.97	18.9	17.1	14.79	16.53	14.09	13.89	20.1	21.1	9.15	8.7	13.38	14.57	20.1	20.9	7.02	8.13	17.6	18.3	15.94	15.66	18.3	20.1	16.92	17.78	27.2	23.1	27.46	30.52	31.4	31.4	24.46	25.88	23	31.23	37	36	23.72	24.3	23.6	28.6	7.67	8.28	21.3	21.4	6.61	5.16	6.62	9.79	15.7	15.1
MPN218	137.76875718664283	140.7475408761948	108.7256136842396	80.42716634206357	109.0979617	MPN123	17.07	15.92	21.7	20.5	11.93	11.24	18.6	28.2	15.44	13.7	20.4	20.8	8.71	7.98	8.77	8.27	19.3	25	3.49	3.17	8.43	6.06	19.2	15.5	5.15	0	10	10.5	6.04	9.42	12.7	10	10.91	12.13	18.7	20.5	17.31	19.9	27.3	27.3	18.94	18.83	25.17	16.63	17.3	14.4	16.83	15.11	22.4	28.9	4.55	6.76	20.5	18.1	6.52	1.47	8.1	8.24	12.3	0
MPN219	190.03550979973738	140.14418143960773	113.79707526576694	131.7355306746556	102.5855408	MPN124	71.89	83.9	77.4	89.7	48.58	49.45	73.8	73.3	51.25	56.86	71.8	87.3	69.46	57.78	58.27	58.74	82.2	94.8	454.15	49.32	65.26	63.03	67.6	68.3	92.3	88.06	50.3	59	53.9	56.62	50.1	60.6	53.18	52.97	62.5	47.9	59.2	57.77	59.4	64	57.24	55.25	77.93	73.75	70.6	57.9	46.97	56.81	59	52.8	53.28	49.3	76.4	72.8	67.82	60.67	56.91	60.27	65.4	74.3
MPN220	149.2719494085198	172.71780556031084	49.15814468662095	46.188336217213575	64.94502099	MPN125	0	18.27	0	22.9	5.23	4.82	13.6	13.6	2.14	4.65	0	0	7.48	3.1	4.62	4.71	23.5	0	3.82	6.69	5.44	4.77	22.8	17.9	7.55	9.15	5.2	7	5.15	3.87	6.5	6.7	5.18	1.71	21.1	21.8	4.66	4.77	20.6	20.7	9.19	7.52	10.51	9.7	7.4	0	7.6	3.92	18.6	21.9	4.3	6.12	22.1	20.9	3	3.08	5.41	5.28	14.5	17.9
MPN221	7.935735249164099	21.702962025974863	16.701844714774417	9.624791860663798	7.633780998	MPN126	31.58	35.65	36.4	40.6	34.76	21.27	34	34.4	18.96	8.18	36.6	41.8	18.45	18.85	29.65	26.91	37.8	37.2	21.76	51.15	27.49	22.01	32.7	36.5	40.57	34.88	33	18.7	25.78	20.39	17.2	23.9	47.25	41.62	30.1	29.8	11.93	11.53	19.6	24.6	14.25	20.58	10.21	6.06	8.6	8.3	15.08	11.64	33.4	37.7	55.13	76.44	25.9	36.8	42.58	26.24	17.92	28.56	39.6	37
MPN223	62.29401673393571	37.9467073695144	9.398938787834616	30.159955276635074	22.48287574	MPN127	0	0	0	0	0	0	13.6	13.6	0	0	0	0	0	0	0	0	0	0	2.93	1.9	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			13.8	0			0	0			0	1.83	0	0
MPN224	9.013560296321236	55.62339648472171	941.7426542019421	44.24171138804666	414.8807794	MPN128	0	0	0	0	46.55	32.94	0	0	42.67	65.35	0	0	29.01	35.37	39.49	45.29	0	0		0	42.7	40.96	0	0	18.93	19.44	39.8	46.1	46.31	51.46	9.8	30.4	51.01	56.33	0	0	44.8	29.61	0	0	14.64	9.98	9.42	6.44	9.5	10.8	40	28.32	0	0	17.71	16.44	0	0	39.48	29.05	0	0	0	0
MPN225	178.17747253571383	207.5243504209102	59.74185839797246	128.3925904083997	138.6115925	MPN129	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN226	60.356601424687376	98.65982923383406	43.33294458109421	45.8478030061717	95.37116822	MPN130	0	0	0	0	6.36	13.56	0	0	12.65	9.89	0	0	13.91	7.86	17.41	4.56	0	0		0	10.67	12.94	0	0	8.37	8.03	13.1	36.2	15.98	3.16	10.1	32.4	16.85	5.02	0	0	10.22	10.22	0	0	6.77	6.31	0	0	3.4	0	8.34	4.52	0	0	19.05	9.05	0	0	12.04	5.57	0	0	0	0
MPN227	370.3792269576345	341.7416578238895	236.73723826784743	210.008840400836	244.3739231	MPN131	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN228	121.8337692388703	135.11422746215118	57.22145273155025	35.04886151449665	64.67005755	MPN132	0	0	0	0	110.66	99.1	0	0	99.63	101.37	0	0	0	105.85	88.21	93.59	0	0		0	93.47	88.95	0	0	61.94	70.52	141.6	125.5	0	99.33	92.8	91.8	84.36	87	0	0	100.95	92.8	0	0	85.06	73.75	87.68	0	111	98.3	115.66	93.86	0	0	36.7	0	0	0	76.31	75.35	0	0	0	0
MPN229	227.39033724056193	188.4165106865429	286.49633838741	242.61852090098986	166.9938117	MPN133	0	0	0	0	4.41	3.91	13.6	13.6	1.3	0	0	0	4.6	1.96	2.34	2.9	17.5	0	2.97	0	3.1	2.08	0	0	1.98	0	2.2	2.8	5.06	3.35	0.7	0	1.77	2.55	0	16.2	0.55	2.2	0	0	1.92	2.42	0	0	0	0	3.89	2.33	0	0	0.62	0	0	0	2.1	0.88	2.4	2.36	0	0
MPN230	7.3476012477911485	31.72013224221651	5.555503381011074	18.8170276139609	30.64487352	MPN134	158.92	158.92	165.9	165.9	153.54	114.85	172.5	180	131.53	139.1	118	165.7	147.46	156.49	161.17	167.34	163	154.1	131.12	157.79	160.91	166.85	142.6	151.9	171.11	163.86	184.1	168.5	166.24	176.32	113.9	104.6	162.09	176.15	116	114.6	135.37	138.18	85.7	121	153.49	145.48	166.77	170.97	210.2	135.4	152.9	157	157.3	122	150.57	159.21	136.7	128.4	109.24	107.75	117.79	117.65	158.4	152.2
MPN231	349.3016868544577	183.20018544412355	443.75156012910924	79.38674691845449	127.8330182	MPN135	0	0	0	0	6.62	5.54	13.6	13.6	0	0	0	0	2.71	2.94	0	0	21.2	23.8		0	4.16	3.09	18.8	20	0	3.33	0	0	0	0	0	0	0	0	0	18.7	0	0	19.4	16.8	5.44	3.41	0	0	0	0	0	0	19.2	20.1	0	0	18.6	18.8	0	0	3.65	3.42	13.7	14.4
MPN232	1.7312413399204614	20.20383941469864	1.626427144711946	6.361137276527216	14.92698691	MPN136	17.97	0	22.6	0	20.41	26.74	13.6	13.6	13.16	9.4	21.9	22.2	10.96	7	0	12.76	0	23.5	6.68	6.65	0	9.13	0	0	5.97	8.67	10.4	7.9	12.53	10.97	7	5.8	9.94	7.92	20.9	0	0	7.31	20.1	19.6	0	5.48	0	0	0	0	0	6.05	16.8	0	0	0	21	0	0	6.53	0	0	0	0
MPN233	46.84092333382381	48.61520073836699	35.840403494896684	58.90600966956922	33.74675615	MPN137	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	3.85	0	0
MPN236	6.0372609846967675	7.586087110554418	10.620521938190107	5.27865227579501	9.324565401	MPN138	0	0	0	0	0.28	0	0	0	1.4	1.38	0	0	0	0	1.53	1.93	0	0		0	0.5	0	0	0	0	0	0.7	0	1.09	1.39	0.2	0	1.37	1.98	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2.52	0	0	0	0	0	0	0	0	0
MPN237	70.13141906107509	79.59359458499397	37.90436222469175	59.55604626767312	73.47101043	MPN139	0	0	0	0	0.28	0	0	0	1.4	1.38	0	0	0	0	1.53	1.93	0	0		0	0.5	0	0	0	0	0	0.4	0	1.09	1.39	0.2	0	1.37	1.98	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
MPN238	32.58488674711145	167.0806691361366	81.2959673019971	111.38711277170545	129.6745492	MPN140	218.93	233.77	226.9	242	235.32	196.44	215.8	227.4	176.92	169.24	237.5	254.5	183	189.27	183.74	194.97	249.6	214.3	128.79	182	200.52	192.62	232.9	206.8	185.35	168.09	159.7	147.9	195.95	195.93	184	188.9	200.24	205.11	152.5	146.2	145.73	138.25	160.1	152.2	147.51	138.33	243.48	193.15	64.6	181.5	155.49	162.84	207.2	178.7	97.57	104.08	197.7	207.5	146.94	155.7	160.27	145.78	193.9	197
MPN239	312.3807149519591	222.77677289939183	86.31572377824561	131.52872207318927	72.99844073	MPN141	241.38	241.38	249.7	249.8	373.92	401.8	267.3	296.6	362.61	372.85	295.2	315.2	446.62	467.35	397.46	402.79	271.2	269.8	334.05	308.25	400.55	403.55	263.7	256.4	305.84	299.47	413.1	391.5	413.36	433.82	399.2	347.1	360.07	342.09	322.8	253.1	391.13	386.06	335.8	335.3	423.79	422.67	556.63	518.64	616.6	518.1	424.33	418.56	293.3	308.9	201.18	211.05	260.8	253.2	371.67	370.18	239.32	269.93	225.8	233.4
MPN240	103.34632839231114	96.20003963327251	86.30517846890909	148.42291847154533	117.6389057	MPN142	140.45	132.15	147.1	138.7	180.43	148.52	141.4	120.1	178.06	177.14	136.1	142.3	201.34	200.34	171.14	153.63	141.2	137.9	113.03	94.53	150.06	162.68	122.8	115.5	122.08	110.53	166.4	178.3	169.87	178.19	174	195.4	186.49	172.29	142.7	125.1	192.87	197.28	162.1	181.3	184.37	174.51	217.67	236.95	277.1	267.3	203.11	174.88	141.3	128.2	130.84	123.57	144.2	139.3	139.57	125.96	150.37	143.3	138.3	134.4
MPN241	18.063256109915006	12.86322785380196	6.349508203230827	4.893500292518766	4.466550603	MPN143	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN243	186.92087008925114	123.29471070575666	156.7821630588352	114.46620063210159	114.1617693	MPN144	0	0	0	0	244.2	256.04	0	0	241.15	234.09	0	0	258.89	263.27	232.1	234.59	0	0		0	233.32	230.25	0	0	155.29	169.67	238.4	265.8	236.43	234.8	207.5	226.2	221.3	224.3	0	0	237.4	243.22	0	0	206.43	212.47	235.78	225.82	260.6	263.2	240.84	246.92	0	0	121.57	118.63	0	0	201.4	194.74	0	0	0	0
MPN244	7.864717773522871	11.748925326168733	9.582115325924057	4.429922663895634	6.083118442	MPN145	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN245	139.12024428391564	225.49347664247867	145.71362066027663	153.62567269397923	169.4497762	MPN146	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN246	33.127140586737966	113.18439709014149	20.152343853552715	57.42037702823269	134.7170384	MPN147	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	16.01	0	0		0	0	0	0	0	0	0	0	5.8	0	0	0	4.5	0	16.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
MPN247	96.97482267134059	103.72928805262015	115.30837136148433	94.08005185788849	110.9662151	MPN148	0	0	0	0	7.5	9.95	18.7	13.6	8.96	14.43	19.3	0	11.25	6.07	0.45	9.41	0	0	1.48	0	9.89	4.67	0	18.7	10.12	3.98	0.8	18.2	8.61	15.39	10.3	8.7	12.84	0	20.4	18.3	9.14	11.79	18.2	20.5	2.05	3.55	0.86	11.71	8.6	2.7	6.02	4.65	16.1	19.1	0	0	0	0	7.29	8.05	3.31	3.47	0	0
MPN248	9.809911923147302	5.027741427023417	22.876869730312983	4.976042284291247	7.367127535	MPN149	0	0	0	0	67.02	40.08	0	0	0	0	0	0	0	90.08	83.08	55.16	0	0		0	0	71.41	0	0	27.64	24.78	44.3	17.9	52.64	55.6	56.6	46.7	84.79	0	0	0	87.89	62.75	0	0	29.63	49.07	22.76	25.18	25.1	0	24.81	75.96	0	0	58.63	36.09	0	0	0	16.38	0	0	0	0
MPN250	209.53681839313438	417.66419701732156	297.3919422758906	521.4929784225841	535.5873838	MPN150	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN251	18.58447940751852	13.239923234285527	29.27359176284465	21.621159074595557	23.86830199	MPN151	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN252	41.586583432167295	113.19425074441462	61.5186145363588	60.534316643654336	49.21489163	MPN152	29.37	39.64	34.2	44.7	17.99	31.86	38.3	40.2	34.03	36.49	38.8	44	32.72	33.37	56.88	29.3	0	38.6	19.94	28.64	44.59	46.78	0	33.1	0	0	35.5	20.1	33.66	32.39	33.6	24.5	33.84	33.99	27.6	26.3	19.4	18.03	23.9	30.2	0.28	3.99	49.94	9.79	50.7	31.4	33.17	34.99	16.6	32	0.19	21.55	24.4	33.3	30.86	25.11	60.07	60.45	18.5	36.8
MPN254	18.632055830285992	13.125044268375818	12.023641946868791	14.410013639160107	12.94147721	MPN153	98.87	98.87	104.8	104.9	106.34	111.78	103.3	103.3	90.34	100.94	107.2	109.7	85.04	87.16	108.48	115.15	100.4	119.2	88.8	95.92	93.26	103.87	103.3	103.8	64.46	63.38	87.8	104.8	91.93	113.08	65.8	62.5	105	93.94	75.8	67.1	80.29	84.69	82.4	86	75.14	75.74	78.54	77.28	70.1	74.2	79.33	74.76	92	106.5	39.23	37.69	137.9	130.5	64.65	59.66	103.05	108	134	130.9
MPN255	85.66787264264522	90.4009042015645	93.71402634209875	90.87420747879032	101.7601802	MPN154	136.99	123.96	143.6	130.4	396.5	351.36	138	101.9	138.45	154.69	101.9	104.4	154.32	96.3	298.14	308.72	97.3	74	143.04	216.34	275.21	78.41	197.5	202.4	143.2	91.65	134.2	216.3	316.77	97.41	364.3	222.3	338.73	130.43	160.2	152.4	167.47	287.51	141.5	157.2	162.86	166.46	292.1	217.44	176.6	194.6	120.36	119.85	105.8	197.3	156.89	172.36	89.6	149.3	141.04	259.07	99.36	265.64	120.3	88.7
MPN256	383.65635506853243	194.44164045875223	98.57982082435933	44.01071543289485	81.1218887	MPN155	92.76	76.6	98.6	82.2	97.24	89.63	91	96.5	90.08	79.1	78.1	94.5	86.6	111.3	94.68	85.51	89.6	91.8	83.3	74.27	111.45	104.53	87.1	87.9	88.77	85.17	128.4	92.4	106.79	98.52	119.2	100.7	109.66	89.94	80.8	82.4	83.56	112.52	67.5	95.9	108.73	103.73	119.85	101.47	123.1	121.4	109.01	88.32	75.7	92.5	92.89	96.55	75.9	70.4	80.5	87.37	95.51	76.77	72.5	71.9
MPN257	48.16710820510771	60.46768451065075	52.42968415777685	50.541971961357085	49.26319915	MPN156	22.08	29.14	26.8	34	18.79	15.99	25	24.3	21.8	21.37	32.7	25.3	14.91	13.93	16.14	15.82	27.5	27.1	10.38	7.38	15.8	16.47	23.8	29.2	12.05	10.92	17	8.2	17.96	16.22	16.4	21.3	18.04	19.19	31.7	32.3	21.22	19.72	19.8	21.3	14.68	13.66	11.59	10.05	11.3	12.4	16.04	15.1	27	24.8	16.18	15.35	28.4	27.3	12.52	11.59	15.66	17.86	23.6	19.6
MPN258	90.81701773603739	79.79298671518444	126.51388006881221	172.97229686543324	137.2754343	MPN157	70	71.89	75.5	77.4	107.73	130.76	68	114.9	123.82	141.05	65.2	65.6	59.19	80.72	74.61	70.61	74.4	48.6	68.17	48.86	65.95	63.29	48.1	55.6	46.42	40.99	60.9	57.6	80.92	85.88	37.5	35	85.97	84.57	51.2	53.8	108.4	87.57	92.1	51.1	70.94	76.42	90.72	67.18	72.8	29.2	79.81	68.24	62.4	87.3	70.42	92.7	58.5	59.1	51.99	48.96	46.29	44.6	75	75
MPN259	12.842261146621674	14.112374896831362	25.637481029697064	32.50550346337839	24.88482105	MPN158	20.24	19.43	24.9	24.1	12.17	13.92	25.1	22	17.35	14.35	22.4	22.9	14.63	12.85	12.82	11.04	23.9	26.3	5.47	3.26	10.97	12.9	22.5	22.5	8.15	10.88	11.9	53.2	14.35	9.12	11.8	2.1	12.84	12.49	25.7	24.9	17.47	14.64	26.9	23.9	15.72	15.37	34.32	11.92	19.4	19.5	15.99	12.27	20.7	21.8	8.76	10.95	21.6	21.2	14.27	5.71	9.44	13.44	16.4	17.8
MPN260	7.296353331933441	13.80085436302261	18.86305299582446	7.041829376345392	13.63117172	MPN159	44.13	29.56	49.2	34.4	21.94	19.18	60	61.2	11.44	9.85	32.2	32.8	23.66	20.39	12.32	14.51	34.4	34.3	8.77	7.35	15.07	14.11	17.4	0	0	0	13	7.8	14.39	12.67	0	13.1	10.32	18.91	16.6	30.1	10.62	11.53	19.2	17.4	0	0	0	24.08	12.7	0	0	7.33	30.3	25.5	0	0	39.8	19	0	13.65	23.32	20.48	12.7	25.2
MPN261	732.2260045486862	389.93940396348086	310.3243543723283	227.8036459105268	298.7017194	MPN160	0	0	0	0	0	0	13.6	13.6	0	0	0	0	11.19	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	13.8	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	17.4	0
MPN262	18.026850693906137	22.901243883681744	18.867263321549355	18.447057001349403	22.31295506	MPN161	73.75	71.35	79.3	76.9	49.52	57.25	105	88.3	45.79	53.18	96.5	90.7	68.03	53.61	63.9	62.21	76.8	92.7	34.23	47.66	64.14	65.07	79.5	91.4	40.08	48.82	52.8	62.2	63.33	62.48	54.8	61.9	56.1	64.18	47.3	47.5	47.73	50.33	66.7	69.4	46.79	43.95	36.61	62.54	46.9	31.7	78.4	59.58	97.2	98.7	47.94	48.1	80.8	101.3	29.14	30.7	36.76	31.85	108.6	79.7
MPN263	707.6565816743653	1330.9471151965379	1483.6787524069996	1156.3966749509361	1265.490701	MPN162	78.76	87.45	84.4	93.3	103.12	111.07	34.4	86	139.33	130.4	92.2	95.9	159.49	164.78	137.42	129.57	47.8	49.4	22.57	31.51	139.71	134.96	70.9	64.3	68.22	70.11	113.1	109.9	77.94	130.17	99.7	99.9	56.76	99.51	65.3	64.1	146.81	145.9	69	70.2	156.61	142.31	125.01	118.94	161.3	134.6	153.66	153.05	82.7	56.8	34.82	35.55	31.5	44.4	51.08	48.65	21.08	20.57	27.2	19.9
MPN264	50.78842287492604	54.66903966056614	26.891993335779727	37.71687165702273	23.89642953	MPN163	0	0	0	0	12.27	90.82	20	13.6	16.11	23	27.6	33.6	17.12	5.91	39.7	37.85	30.7	26.1		0	7.32	23.18	25.2	30.2	24.13	0	15.6	18.7	23.1	22.76	12.9	0	38.88	23.82	27	31.2	4.52	33.17	26.6	26.8	3.14	26.99	21.92	9.22	21	0	5.61	30.85	22.3	54.5	0	0	26.1	26.3	11.92	26.95	0	3.86	28.7	28.4
MPN265	42.638032698824794	33.21526305797793	10.812628189899572	17.12588385235903	17.64413619	MPN164	92.06	90.79	97.9	96.7	131.68	154.31	64.3	63.5	213.46	196.74	101	100.3	112.83	103.98	77.05	104.04	83.8	82.9	124.78	81.94	94.08	82.43	83.8	94.2	109.33	106.37	155.3	136.8	79.41	124.2	173.5	166.9	110.18	124.66	113.9	113.8	186.61	183.42	97.3	95.2	194.48	181.34	214.18	210.54	232.9	223.1	171.31	163.82	81.6	83.2	130.48	122	69.9	69.9	95.38	95.17	75.24	85.74	74.4	73.8
MPN266	151.94005347560062	128.8800117242614	143.4847045878056	134.26068787125146	164.2387424	MPN165	82.27	79.64	88	85.3	172.47	143.54	77.5	73.8	153.35	233.86	82.8	82.9	90.72	92.99	73.41	93.64	87.9	94.4	84.07	57.38	69.02	56.31	115.1	120.7	52.1	64.66	96.4	102.9	112.13	151.55	93.6	163.6	206.41	192.86	171.8	171.7	217.01	225.46	149.2	150.6	120.58	129.7	106.4	95.36	96.4	75.5	120.44	95.38	115.8	112.7	127.77	99.6	116	110.9	96.75	62.52	112.58	96.08	113.7	120.3
MPN267	1011.7372463522607	774.8426727500932	421.4749312753531	690.9425103045938	330.6653442	MPN166	123.96	122.84	130.3	129.2	222.27	198.58	120.1	129.4	279.97	256.32	132.5	138.6	137.31	128.55	103.1	94.61	116.6	116	83.97	65.37	106.14	101.55	171.6	169.1	116.68	80.77	225.4	177.9	157.39	154.38	245.8	254	205.94	191.03	269.7	257.3	293.24	265.19	233	273.2	248.06	243.15	243.14	229.82	250.5	278.4	206.91	188.17	174.6	159.8	165.36	163.23	141.6	142.7	120.25	111.61	130.28	135.36	140.7	137.1
MPN268	85.10072947315997	65.17207773024546	45.422963251922894	24.41708695453091	45.96157545	MPN167	99.77	97.5	105.8	103.5	287.08	409.64	124.9	165.7	438.41	405.85	151.6	182.6	184.27	188.89	151.76	120.25	138.6	162.2	202.21	157.41	108.99	157.14	240.3	235.4	167.48	168.35	256.2	343.4	173.75	233.44	413.8	409.1	237.79	324.4	397.7	373.6	421.71	440.11	284.6	202.8	381.88	388.65	375.68	377.52	390	386.1	277.05	287.87	229	229	128.66	188.88	191.6	174	163.4	172.87	208.26	204.75	183.5	185.6
MPN269	59.5236159546504	32.007080782451204	29.618492678173094	29.522949181238026	16.81566036	MPN168	68.94	70	74.4	75.5	259.29	278.74	66.1	104.2	335.35	299.41	85.2	82.1	105.35	106.71	90.7	93.64	143.5	125.2	54.29	70.25	78.94	91.53	157.4	90.4	85.57	86.38	183.2	209.5	136.53	121.93	195.4	191.8	192.85	200.66	191.6	217.7	268.19	215.67	248.1	164.5	158.54	195.62	220.49	175.67	144.4	124.7	153.21	131.77	150.6	137	148.7	125.05	154.1	101.9	111.96	107.45	86.01	77.48	145.8	150.6
MPN272	20.953306482106157	71.1309615307406	21.83555095004227	13.095816540941025	24.17901287	MPN169	38.69	41.01	43.7	46.1	116.67	107.15	40.4	41.9	196.29	204.99	39	48.7	61.06	73.47	65.2	66.87	31.6	38.9	23.61	16.66	60.51	62.11	64.7	63.8	38.85	47.16	93.9	31.4	85.73	87.05	131	57.2	123.41	107.83	76.4	79.6	154.39	141.97	90.2	87.3	60.26	90.15	55.66	80.47	32.1	75.4	99.27	126.89	63.6	48.8	92.27	84.03	49.7	35.2	51.46	44.01	113.27	109.48	37.4	52.8
MPN273	386.3308345182785	576.8859092438528	853.5823182512343	634.3134659469384	673.4686176	MPN170	49.35	46.14	54.5	51.3	53.22	52.01	44	42.5	28.22	30.5	59.4	65.1	12.36	21.43	20.57	10.04	63.6	62.1	31.64	24.9	15.25	15.72	63.2	60.9	40	36.36	8.4	21.9	12.41	13.03	12.4	74	9.56	17.15	121.2	123.8	56.55	57.45	107.3	104.9	57.05	57.11	90.72	97.47	90.6	113.4	42.17	51.52	72.7	67.4	12.71	20.63	62.5	59.5	14.73	19.83	25.16	29.9	56.2	60.6
MPN275	5.858046971413502	5.600864417570759	10.058695277717591	4.572134215272595	7.186823474	MPN171	86.96	86.57	92.7	92.4	155.97	162.63	91.3	89.4	212.67	234.32	76.2	73.2	93.46	99.57	77.45	82.91	67.5	88.2	72.93	94.93	76.24	80.34	108.2	77.9	65.89	68.91	135.6	132.4	111.11	113.23	143.8	145.8	128.41	138.29	130.6	157.5	199.22	221.74	210.3	169.4	166.26	164.33	152.81	152.95	144	141.4	132.21	148.57	118	117.2	91.94	94.64	127.1	98	71.5	78.17	101.21	103.99	107.6	124.6
MPN276	4.130371057626135	5.494245926457212	2.0768094623605147	4.2388611011728665	6.749630753	MPN172	47.8	29.7	52.9	34.5	116.54	121.83	44.9	52.5	179.03	134.41	54.4	52	68.08	63.71	49.17	50.57	51.5	40.5	29.97	18.92	39.98	49.86	66.6	62.4	53	47.34	77.9	68.7	67.04	72.29	72.2	72.5	92	104.03	68.6	71.4	165.99	158.81	92.6	67.7	109.19	119.77	127.94	96.38	86.9	88.9	102.21	108.89	65.2	65.2	65.72	62.06	66.2	52.5	77.86	71.83	47.32	41.62	52.8	49.4
MPN277	242.1686817869444	199.32345329713496	126.6728488182145	102.45598071180305	172.3123311	MPN173	58.76	57.58	64.1	62.9	38.24	45.53	46.4	48.5	79.67	110.35	60.6	64.4	34.39	36.25	33.16	36.49	48.6	52.6	6.97	22.76	22.04	30.85	56.4	51.2	27.33	16.72	36.1	48.5	33.86	202.91	47.4	49.5	31.69	38.83	64.9	69	64.34	77.56	58.4	55.4	37.12	37.98	110.22	29.92	90.7	89.5	55.11	59.41	39.2	37.4	25.12	21.6	32.3	31.4	31.32	35.7	33.53	33.06	28.4	29.6
MPN278	1.7302650902215628	2.174115701628691	3.197228970820713	9.779759199086737	16.55036174	MPN174	40.58	36.7	45.6	41.7	162.07	153.87	39.7	42.2	278.66	245.78	40.1	45.9	83.71	75.26	95.73	94.78	45.8	37.8	20.4	21.89	72.19	69.17	57.9	54	47.63	53.07	107.1	119.3	100.1	125.92	103.9	96.1	123.37	173.67	64.1	67.6	181.15	197.24	52.6	63.6	87.44	46.09	76.93	78.9	62.1	16.1	118.43	97.64	52.5	65.7	89.36	94.13	45.3	44.2	60	67.94	58.06	86.98	51.2	48.5
MPN279	18.89752973922268	23.032432308861342	26.859780079751022	20.40113066703531	17.73565632	MPN175	19.43	19.29	24.1	24	62.25	29.77	20.2	23.9	120.58	104.29	28.8	30	14.43	30	8.61	7.61	27.6	31.5	10.02	21.3	27.04	25.43	36.2	36.1	18.37	10.91	63.6	10.7	37.77	41.14	65.8	67.3	11.85	52.74	57.6	50.3	101.63	98.31	46	47.4	43.41	37.73	28.1	19.54	42.9	41.8	53.81	62.82	38.8	42.8	40.04	37.86	35.5	35.7	17.65	20.54	16.11	33.21	33	27.8
MPN280	23.27337885526951	23.883828125738848	41.43424505070968	61.50276518276884	47.15720702	MPN176	59.91	21.16	65.2	25.9	201.32	186.96	60.5	26.4	192.34	321.98	62.4	66.6	108.3	111.38	54.94	104.75	59.8	57.6	91.3	63.53	90.35	93.34	87.1	99.4	78.03	81.93	76.9	153.6	75.86	135.12	157.8	171.2	121.86	208.39	114.7	144.1	244.62	240.48	102.8	128.2	54.27	155.98	112.43	117.85	105.6	130.2	154.27	155.58	104	97.1	137.09	133.36	70.4	63.7	106.56	104.32	113.01	117.39	83.2	80.2
MPN284	69.17346238446773	69.54536266885214	131.28081834496837	136.48742308119395	79.2147714	MPN177	135.29	138.41	141.8	145.1	185.49	206.93	144.9	148	202.33	209.23	140	140	123.53	99.99	86.41	79.39	66.2	110.2	130.46	83.44	100.94	83.32	169.6	114.2	100.12	128.95	147.1	138.9	99.28	104.03	179.9	178.3	128.13	131.02	184.3	178.9	267.13	270.98	299.1	243.6	301.74	269.73	359.01	259.83	266.4	313.1	241.91	216.59	139.1	210	138.44	122.34	129.6	137.8	119.07	100.21	141.77	135.86	172.6	128.1
MPN288	9.758920012756189	11.34958099244709	12.854260277232958	20.850556002758225	14.83183879	MPN178	26.16	27.27	30.9	32.1	78.8	71.19	81.7	13.6	115.93	122.83	35.9	35.2	47.29	48.74	28.42	33.78	34.2	0	72.59	78.59	41.02	40.79	47	48.4	12.94	49.74	79.5	32.3	46.31	45.25	141.5	50.4	41.44	17.61	50	69.9	109.42	114.45	73.3	72.1	101.74	99.52	85.52	89.33	82.3	57.3	80.53	83.37	59.6	67	54.98	52.27	59.9	41.6	52.09	51.05	50.89	43.24	62	0
MPN291	70.17837767231015	18.647397487040692	15.372406539596946	17.043320316805065	16.57546445	MPN179	30.61	31.99	35.5	36.9	45.33	45.84	33.2	44	42.89	76.45	27.9	29.7	20.68	20.59	6.87	10.39	38.4	38.4	48.55	46.23	12.12	18.85	70.3	69.2	18.69	21.3	30.3	36.8	14.43	23.6	35.9	51.9	13.1	16.42	112.9	106.6	40.24	58.75	118.1	122.7	73.8	72.82	59.54	58.27	51.4	51.7	43.85	45.44	80.2	108.1	22.63	28.06	74	67.1	27.66	22.1	64.13	54.9	61.6	63
MPN294	129.78097449732482	183.18043789030474	392.7226366527457	382.58349819083	469.7800901	MPN180	122.84	129.75	129.2	136.3	127.53	128.04	117.1	115.7	201.98	208.54	125.7	124.5	88.56	88.9	70.43	75.38	114.5	106	138.67	78.02	70.72	72.42	144	142.2	99.47	78.81	122.2	143.3	92.75	97.56	176.2	205.3	127.28	140.39	214.3	203.1	187.31	181.7	178.9	191.2	168.19	155.22	201.49	230.44	208.3	233.4	124.65	126.94	122	118	133.28	133.3	112.9	114.6	82.25	82.28	117.01	116.59	125.9	125.9
MPN295	239.71499052605407	356.4702916035514	671.2019729440517	369.4431030958249	532.4492963	MPN181	42.77	37.9	47.8	42.9	125.67	164.98	42.5	46.9	224.15	237.07	48.6	52.9	85.02	89.27	73.27	66.92	55.1	53.8	34.94	31.36	59.6	63.69	68.5	67.7	62.46	45.77	88.9	142.8	91.24	98.98	119.1	147.5	116.35	123.29	94.3	95.4	206.1	212.2	93.6	92.5	82.31	139.54	123.07	119.65	96.9	111.1	134.39	149.96	72.1	77.6	97.3	97.83	64.9	58.8	75.11	74.65	72.8	75.68	63.7	65.8
MPN297	214.72384041582083	202.8770078778573	177.70248869664863	82.77974268191501	61.30735859	MPN182	90.18	43.97	96	49.1	170.66	195.72	63.1	53.4	232.65	231.92	102.4	111.5	121.86	123.31	83.87	83.18	96.6	101.4	105.33	106.06	103.37	104.1	116.7	89.2	105.42	81.36	140	110.8	113.32	118.54	187.1	90.5	66.14	89.16	111.7	175.7	272.22	260.24	205.3	207.1	269.02	250.14	252.06	236.09	172.3	261.1	216.04	209.11	135.2	133	68.35	84.62	110.2	113.9	78.53	102.55	104.46	145.54	91.4	96.6
MPN299	33.36238853752188	87.40643873910672	41.514284365394204	63.10171224342357	69.14015357	MPN183	39.02	25.25	44	30	102.1	125.62	58.6	37.4	184.55	138.07	27	61.3	39.96	63.61	48.01	51.38	31.1	28.3	52.18	53.52	44.51	34.76	43.7	38	35.5	45.46	51.8	77.1	67.7	67.28	77	71.3	86.3	62.93	87.8	89.8	146.88	122.91	85.7	58.7	103.95	70.42	55.88	92.62	97.9	55.9	84.59	91.9	46.9	40.3	73.99	50.24	46	56.7	42.5	59.27	44.85	32.03	54.4	64.9
MPN300	5.389438300212071	17.672683891352197	15.481855311621906	24.975445825573907	15.04368958	MPN184	12.84	13.37	17.4	17.9	84.56	84.01	13.6	18.9	33.26	31.1	22	21.2	1.41	14.91	28.45	27.53	26.3	22.1	3.15	11.13	26.36	26.5	34.6	31.9	5.24	7.53	30.4	18.3	35.2	34.73	9.5	24.8	23.3	34.37	26.3	23.8	38.92	23.56	35.9	35.9	15.66	15.52	11.59	23.03	18.8	17.6	32.65	55.22	38.1	36.8	7.93	4.39	32.9	35	18.05	8.38	21.8	21.94	27.6	30
MPN301	45.27175951867225	56.715175457863815	109.9170216254009	126.9817646106425	59.22469652	MPN185	73.11	73.11	78.7	78.7	72.55	75.01	78.1	70.8	94.9	104.47	87.2	85.8	64.27	78.02	64.6	71.86	80.8	81.7	77.88	80	65.39	67.97	62.8	60.3	79.21	82.06	62.5	90.9	71.82	80.32	95.3	120.2	71.69	79.92	82.4	78.8	103.22	104.62	77.7	90.6	115.8	119.31	136.91	122.94	151.1	150.2	92.08	91.73	56.2	71.3	101.01	101.91	61.3	60.6	63.38	68.64	63.64	62.28	68.6	64
MPN302	112.68010206123598	89.15348732253666	154.78036008579016	159.73333150143492	61.04537398	MPN186	35.65	37.36	40.6	42.3	5.65	10.17	38.5	39.6	17.48	18.86	36.8	36.1	8.77	9.28	6.97	8.92	40.7	40.8	14.69	17.18	10.86	5.08	40.3	39.2	13.45	12.18	12.9	12.6	8.04	7.34	15.5	19.5	13.46	14.1	48.9	48.1	13.47	13.94	46.8	38.1	25.77	23.07	9.61	13.49	13	14.4	14.75	10.34	37.5	34.3	7.33	7.89	35.3	37.6	6.95	7.62	13.93	11.02	0	30.7
MPN303	442.76898665508867	437.96671971143724	499.43573303835154	447.57125301209567	418.2774267	MPN187	62.85	59.91	68.2	65.3	31.61	42.33	75.7	67.6	66.31	36.25	68.5	69.4	39.9	37.78	26.55	24.3	92.7	82.5	56.95	17.14	18.77	18	67.6	65.3	48.65	31.39	37.9	29.5	31.1	29.04	60.3	62.2	58.65	32.45	64.6	65.3	52.41	49.03	55.8	60.4	56.63	100.94	78.92	60.51	90.6	83.4	51.96	34.03	49.6	32.5	38.26	55.86	0	74.4	29.5	20.23	21.09	33.53	16	68.2
MPN307	4.127533837593864	5.465684076438604	5.18297628020124	9.14088544442649	4.561019125	MPN188	0	0	0	0	1.15	1.45	13.6	13.6	2.28	2.09	0	0	0.27	0.52	0.79	0.81	0	0	0.37	0	0.4	0.55	0	0	0.14	0.28	0	0.6	0.52	0.58	0.9	0.6	1.07	1.4	0	0	1.07	0.74	0	0	1.25	0.7	1.21	0.62	0.6	0.5	0.34	0.3	0	0	0.46	0.52	0	0	0.52	0.32	2.22	2.28	95.1	0
MPN309	200.64488434396995	157.84064262300942	85.34095754003646	57.78572672309925	108.2144744	MPN189	71.35	72.63	76.9	78.2	176.61	135.91	69.3	71.6	193.75	193.99	80.7	80	82.02	88.36	55.58	56.74	59.5	61	87.59	50.22	78.59	77.09	76.3	74.2	59.8	65.87	126.2	128.1	81.49	88.06	142.9	120.1	66.14	87.13	116.8	115.9	202.09	203.53	87.4	104	142	154.91	127.11	135.79	155.6	151.8	138.72	123.02	78.7	88.9	92.02	91.7	71	69	62.85	55.67	74.41	77.36	68.2	62
MPN310	134.71805440950473	464.1110996966014	213.9204266768465	270.1763176159119	322.7311631	MPN190	44.62	44.36	49.7	49.5	88.6	106.06	45.1	50.8	147.13	143	61.5	55.1	63.92	80.02	66.19	70.34	50.3	51.2	49.69	36.31	64.62	68.74	58.7	59.6	43.31	48.12	83	69.7	72.51	72.74	104.9	98.4	92.8	112.09	77.7	74.4	123.39	139.16	75.8	73.2	74	78.29	71.61	69.21	55.6	48.5	85.78	86.07	57.5	62	72.91	70.67	59.5	54.4	65.39	59.8	56.59	55.84	54.8	55.9
MPN311	170.29287032884943	123.4144959152216	121.02274205917416	60.27219565810824	81.79797977	MPN191	272.02	281.68	280.8	290.7	425.53	433.49	302.8	325.5	437.88	465.09	300.8	295.3	379.26	330.2	311.59	322.7	286.3	253.3	486.96	363.65	313.35	329.5	328.2	268.7	328.82	339.08	380.1	358.7	331.46	366.99	452.8	473.4	382.02	377.53	458	433.6	436.15	578.75	511.2	529	564.23	573.18	568.26	583.44	414.5	384.3	471.49	468.82	344.5	284.2	272.53	298.44	236.4	240.5	362.17	362.63	386.01	381.35	218.2	258.3
MPN312	4.93528855875197	11.104399254344525	4.93528855875197	2.4133561045427605	5.52752319	MPN192	37.15	37.15	42.1	42.1	101.03	100.88	57.5	62.7	179.73	180.35	73.7	73.7	59	59.54	46.61	47.5	55.8	60.3	57.1	48.93	51.79	51.12	39.9	48.1	49.63	33.95	87.5	81.2	63.29	66.73	97.3	99.2	81.07	83.07	59.5	58.4	143.82	145.83	56.3	55.7	83.88	69.5	74.6	73	61.1	67	81.76	82.56	42.2	44.9	50.75	49.07	34.3	34	78.89	14.78	36.04	35.69	37.2	33.7
MPN314	1253.6318325088134	1157.1986153142027	567.8845055145947	685.7473283879331	803.6101497	MPN193	36.9	27.67	41.8	32.5	36.9	36.02	45.8	43.1	40.38	34.29	44.9	39.5	24.71	40.99	39.32	56.09	57.9	47.3	29.44	29.18	53.66	39.92	50	35.4	28.39	25.4	28	39.9	35.68	39.21	27.4	42.8	46.57	45.05	40	38.8	29.96	33.64	48.4	46.9	33.83	25	21.19	18.81	22.7	22.8	27.1	28.03	39.9	35.4	39.73	28.19	42.9	32.3	18.2	19.29	39.41	34.33	38	46.8
MPN315	144.49923886158285	273.7880316441789	701.8534458538694	561.7000486437354	662.7408699	MPN194	57.21	64.01	62.5	69.4	49.9	44.58	70.8	72.6	40.17	42.73	64.9	66.2	43.32	42.91	45.01	45.78	55.4	59.9	49.3	42.72	50.32	45.41	51.2	51.7	43.5	36.61	50.9	53.7	48.56	46.6	58.9	53.2	38.17	48.65	49.7	49.1	43.81	40.33	45.5	42.2	31.83	42.56	45.64	40.7	47.7	37.8	41.29	41.61	46.5	48.2	46.98	52.95	59.1	57.6	27.07	26.18	45.39	45.72	49.9	58.2
MPN316	2.565735689300991	5.017736027387142	8.195635505570621	5.251897037723051	7.560055613	MPN195	30.1	31.11	34.9	36	49.8	235.56	35.6	40.8	19.73	19.91	37	27.8	18.06	19.11	21.47	21.95	29.1	33.8	24.03	20.7	21.03	21.95	32.3	31.3	13.09	8.87	24.3	17.5	24.64	25.06	20.4	25.2	19.41	18.54	32.7	31	17.64	16.93	26.3	20.4	11.12	17.03	13.84	14.09	10.4	21.8	17.44	17.34	32	21.4	3.94	6.42	39.6	39.3	16.07	15.25	37.45	37.75	31.8	26.1
MPN317	77.21946388811502	41.34698905556986	22.47432159688389	15.559145716173065	12.43290995	MPN196	14.58	14.58	19.2	19.2	5.78	3.96	13.6	13.6	2.69	2.04	0	19.6	5.54	2.2	0	0	0	18.8	4.19	5.07	4.43	1.74	0	18.9	5.94	0	0	1.3	0	0	5.1	0	0	0	0	19.8	4.79	8.83	20.5	19.2	6.6	5.16	8.94	10.5	4.9	0	7.45	4.34	19.9	0	0	0	0	17.8	0.99	6.41	3.06	1.71	0	0
MPN319	4.2790498103001795	4.2790498103001795	4.2790498103001795	4.2790498103001795	58.62298238	MPN197	127.66	127.66	134.1	134.1	128.45	145.79	134.2	124.9	149.06	199.03	108.9	127.8	140.9	129.86	113.66	119.7	148.5	135.5	157.29	156.09	130.65	120.69	149.2	148.7	114.26	103.88	138.8	122.8	111.44	116.11	145.3	140.3	119.13	125.97	140.4	136.6	138.91	147.65	171.7	197.2	161.3	172.68	159.57	137.91	179.8	128.2	94.74	148.57	186.2	171.5	67.4	73.07	169.8	160.1	122.47	125.31	141.28	140.7	177.6	170.4

TIME h	Glucose	Lactate	Acetate	Protein mg/ml	molecules glucoses/cell/s	TIME h	pH	Glucose	Lactate	Acetate	protein	molecules glucoses/cell/s					WODKE paper MSB modeling metabolism
0	52.21	4.7315E-5	5.299E-6	0.023376		0	7.9064	60.317	0.0037048	0.0021653	0.0079953						Time Hours	Protein in concentration mg	Glucose mM	lactate mM	acetate mM
16.839	59.103	0.52636	1.3715	0.0074101	3971	14.129	7.8784	60.836	0.025809	0.57419	0.0044266	12982					0	0.005	60	4	1.5
						20.71	7.8627	59.603	0.014315	1.0263	0.0047978	24921					15	0.009	58	4	3.3
30.387	52.495	0.98531	1.8481	0.018839	5082	31.161	7.8291	59.271	0.78443	1.75	0.011811	16903					25	0.013	57	4.5	5
38.129	55.492	1.3769	2.3426	0.023362	18455	38.903	7.805	59.887	1.9383	2.4438	0.014066	16594					31	0.02	55	5	5.7
48.968	47.746	5.6969	3.6089	0.037265	10222	50.71	7.7583	54.47	4.4025	3.274	0.018969	22749					37	0.021	52	7	6.2
57.484	46.477	9.4358	3.7477	0.043614	21848	59.806	7.6959	52.19	8.4369	3.9317	0.024116	35913					42	0.029	50	11	7.8
68.323	37.659	20.834	4.6963	0.055532	29026	69.677	7.5734	46.825	17.6	4.9883	0.031837	48669					48	0.031	48	15	8.5
76.065	31.028	34.897	5.551	0.070175	16729	78.194	7.3817	39.065	32.331	6.0332	0.038412	32017					52	0.037	43	20	9.2
110.9	15.055	82.097	7.238	0.06159	-1320	93.097	6.9224	30.213	52.866	7.4079	0.042395	25142					60	0.042	33	25	10.2
129.48	13.129	80.202	7.3275	0.065479	3321	110.52	6.0605	19.325	73.732	8.7422	0.047348	10580					72	0.048	21	53	12.1
144.19	13.742	83.697	7.6564	0.075757	2157	134.13	5.0941	10.879	81.24	9.6941	0.046939						84	0.057	15	77	14.1
																	96	0.046	12	80	15.2
																	108	0.052	9	90	16.1
			mM			molecules/ml.sec					molecules/cell.sec						124	0.044	11	98	16.2
time1	time2	dt	Dlac mM	Dace mM	D glc used	lac	ace	glc	ATP	cells/ml at t1	lac	ace	glc	ATP			136	0.048	10.5	90	16
0	24	24	0.49912	1.3684	0.93376	3.4793978703703706E12	9.539205092592592E12	6.509301481481482E12	1.6273253703703707E13	728300000	4777.4239604151735	13097.90620979348	8937.665085104329	22344.162712760823			148	0.048	10.5	90	16.1
24	48	24	4.72968	0.9328999999999998	2.83129	3.2970905833333332E13	6.50330636574074E12	1.9737106099537035E13	4.9342765248842586E13	2102600000	15681.016757030977	3092.983147408323	9386.99995221965	23467.499880549123			155	0.048	10.5	90	16.2
48	72	24	21.2762	1.8657999999999997	11.571	1.4831776921296294E14	1.300661273148148E13	8.066219097222222E13	2.0165547743055556E14	3.4384E9	43135.693698511786	3782.751492403874	23459.222595457835	58648.05648864459			165	0.042	10.5	90	16
72	96	24	37.405	1.6493000000000002	19.52715	2.6075267939814812E14	1.1497377199074076E13	1.3612502829861111E14	3.4031257074652775E14	5.1852E9	50287.873061434104	2217.3449816929096	26252.60902156351	65631.52255390877			180	0.051	10.5	90	16.2
96	120	24	8.881	-0.16129999999999978	4.35985	6.191002662037037E13	-1.1244327546296282E12	3.039279693287037E13	7.598199233217592E13	4.8651E9	12725.334858557968	-231.12222865503858	6247.106314951465	15617.765787378661
120	144	24	-7.923000000000002	0.03230000000000022	-3.945350000000001	-5.523174652777779E13	2.2516539351852E11	-2.7503290567129637E13	-6.875822641782409E13	5.0571E9	-10921.6243554167	44.52460768395325	0	-13596.374684665934


t0 (h)	t (h)	dt	cells/ml	D lac (mM)	Total lac/ml	lac/cell.sec	D ace (mM)	Total ace/ml	ace/cell.sec	gluc /cell.sec	Produced ATP/cell.sec	D gluc (mM)	Total gluc/ml	gluc/cell.sec	Produced ATP/cell.sec (max)	Produced ATP/cell.sec (min)	ATPs for protein/cell.sec (assuming cell# of t0)	ATPs for protein prod/cell.sec assuming average cell number		Dmole ace+lac	dpH	b if pH change only by ace+lac	pH change should be (HCl)	ratio	t1/2	k	0.014926600860541634	t0 (h)	dt	1.4926600860541635E9	Dcells/ml
18.25	26.75	8.5	1.4926600860541635E9	0	0	0	0.45211269575024504	2.72307476650372544E17	5961.797483954494	2980.898741977247	10433.145596920365	1.2326388888888857	7.4241840277777587E17	16254.229300523331	56889.80255183166	39010.15032125599	381.9353581195087	402.1644842165756		4.5211269575024506E-7	0.04369461514422124	1.0347103281673794E-5	0.0054255693717778115	8.05346170145894	20	0.03465735902799726	0.01529781489918164	18.25	8.5	1.529781489918164E9	3.712140386400056E7	2.4869294898968413
26.75	40.25	13.5	1.529781489918164E9	0.7701149425287368	4.6384022988505818E17	6238.824116290289	0.7237473871076312	4.3591305125492627E17	5863.193146159066	6051.008631224677	21178.530209286368	0.33203125	1.99982421875E17	2689.8381728058894	9414.433604820613	6455.6116147341345	2134.254247000957	2114.627172171829		1.493862329636368E-6	0.033569603109482316	4.450044657258402E-5	0.017927065038237947	1.872565477833614			0.02231080739053404	26.75	13.5	2.2310807390534043E9	7.012992491352403E8
40.25	50.25	10	2.2310807390534043E9	1.1538461538461529	6.9496153846153779E17	8652.527379030491	0.6937696846830539	4.1785748108460333E17	5202.479699266616	6927.5035391485535	24246.26238701994	-0.61631944444445	-3.7120920138889222E17	-4621.691418313208	-16175.919964096227	-11092.059403951698	3869.629989390979	3781.097550306212		1.8476158385292067E-6	0.024081764061146593	7.672261192485236E-5	0.022172276953428615	1.0861204788181533			0.024565510841137266	40.25	10	2.4565510841137266E9	2.2547034506032228E8
50.25	65.5	15.25	2.4565510841137266E9	2.4641909814323615	1.48418222811671117E18	11004.975569194396	0.8301988202071469	5.0002874941076448E17	3707.633784392389	7356.304676793392	25747.066368776872	5.4166666666666785	3.2624583333333407E18	24190.610542080125	84667.13689728043	58057.4653009923	2381.429450550757	2349.445435853442		3.2943898016395085E-6	0.04676281607554689	7.044891813866197E-5	0.039534258990033704	1.182842862625437			0.029469332658398722	50.25	15.25	2.9469332658398724E9	4.9038218172614574E8
65.5	77.25	11.75	2.9469332658398724E9	4.0344827586206895	2.4299689655172408E18	19493.510593138897	0.6576740838044817	3.961171006754393E17	3177.700212519589	11335.605402829244	39674.618909902354	2.2808159722222214	1.37373546006944384E18	11020.27520640952	38570.96322243332	26448.660495382846	2858.287120339971	2791.690866600189		4.692156842425171E-6	0.062306606109505225	7.530753374976969E-5	0.056308134434479434	1.1065293981992186			0.03461570910318063	65.5	11.75	3.4615709103180633E9	5.146376444781909E8
77.25	90	12.75	3.4615709103180633E9	9.163351016799295	5.5190863174182144E18	34736.11694952898	1.0565610630049687	6.3636672824789261E17	4005.175462729206	19370.64620612909	67797.26172145182	5.364583333333329	3.2310885416666639E18	20335.87862240922	71175.57517843226	48806.108693782124	2711.804760000786	2643.290350617124		1.0219912079804264E-5	0.12252135998098801	8.341330916821457E-5	0.12264385071167963	0.9990012484932523			0.04233738294102758	77.25	12.75	4.2337382941027584E9	7.721673837846951E8
90	101	11	4.2337382941027584E9	14.730327144120249	8.8720760389036268E18	52918.3215048531	1.0449370559423796	6.293655887940951E17	3753.909505042157	28336.11550494763	99176.4042673167	7.760416666666671	4.6740989583333356E18	27879.097331671237	97576.84066084932	66909.83359601097	2999.89701503653	2929.9461102017085		1.5775264200062632E-5	0.19176946261276306	8.226160716692086E-5	0.18931074283046478	1.0129877456796001			0.04891166793216907	90	11	4.891166793216907E9	6.574284991141481E8
101	120.25	19.25	4.891166793216907E9	20.53492484526968	1.2368185234305927E19	36488.85817012686	1.3746917826127145	8.2797686066763789E17	2442.7132731848797	19465.78572165587	68130.25002579554	8.851996527777779	5.3315575086805555E18	15729.263596450088	55052.4225875753	37750.23263148021	2437.868569263136	2421.871629373696		2.190961662788239E-5	0.45927144532222464	4.770515748591906E-5	0.26292591657125153	1.7467713008723675			0.05289483675018983	101	19.25	5.289483675018983E9	3.9831688180207634E8
120.25	142.75	22.5	5.289483675018983E9	20.866489832007062	1.256788682581785E19	29333.505148681335	1.334313652816352	8.0365711309128883E17	1875.7393658423262	15604.622257261832	54616.17790041641	10.88758680555556	6.557593532986113E18	15305.453202176652	53569.08620761828	36733.08768522396	2224.9798048941143	2216.213893288781		2.2200803484823415E-5	0.8618702078475984	2.5758870979270592E-5	0.35521285575717465	2.426348579108796			0.05784822407829241	120.25	22.5	5.784822407829241E9	4.953387328102579E8
142.75	173.25	30.5	5.784822407829241E9	13.187444739168882	7.9427979664014172E18	12504.92654629627	0.9519449994416487	5.7335647316370496E17	902.6769423173403	6703.801744306806	23463.306105073818	8.446180555555554	5.0871345486111099E18	8009.047206110567	28031.665221386982	19221.71329466536	2193.395840676057	2193.979316583323		1.4139389738610532E-5	0.9664560821712032	1.4630142020365293E-5	0.6787993153437605	1.423772918335615			0.05743904496751878	142.75	30.5	5.743904496751878E9