External metabolite concentration times series

Selected Cell

Cell:

Value:

growth_curveA carOlina GC b AND c gene names metabolic reactions AA import rates protein copy numbers todos datos GC A

	molecules/cell.sec				Uptake in mmol/L-cells
time HOURS	lac/cell.sec	ace/cell.sec	gluc /cell.sec	Produced ATP/cell.sec	Glucose uptake mmol/L		mol/cell/s, uptake
24	4777.4239604151735	13097.90620979348	8937.66508510433	22344.162712760823	0.2215125483129287		1.484133950473513E-20	446.6666666666667
48	15681.016757030977	3092.983147408323	9386.99995221965	23467.499880549123	0.23264893690131397		1.5587477478207387E-20	4.71303294282827	Vmax lactis =3.7 (intern to extern volume ratio 0.047
72	43135.693698511786	3782.751492403874	23459.222595457835	58648.05648864459	0.581417196670381				model predicts 0.045mmol/s glucose uptake, so that about 1 mmol/L..?
96	50287.873061434104	2217.3449816929096	26252.60902156351	65631.52255390877	0.6506489411783134			6.7E-17	Cell Vol. in L
120	12725.334858557968	-231.12222865503858	6247.106314951465	15617.765787378661	0.15482930119108781			6.022140857*10^23	Avogadro's number
144	-10921.6243554167	44.52460768395325	0	-13596.374684665934	0

t0 (h)	lac/cell.sec	ace/cell.sec	gluc /cell.sec	Produced ATP/cell.sec	dpH
18.25	0	5961.797483954494	2980.898741977247	10433.145596920365	0.04369461514422124
26.75	6238.824116290289	5863.193146159066	6051.008631224677	21178.530209286368	0.033569603109482316
40.25	8652.527379030491	5202.479699266616	6927.5035391485535	24246.26238701994	0.024081764061146593
50.25	11004.975569194396	3707.633784392389	7356.304676793392	25747.066368776872	0.04676281607554689
65.5	19493.510593138897	3177.700212519589	11335.605402829244	39674.618909902354	0.062306606109505225
77.25	34736.11694952898	4005.175462729206	19370.64620612909	67797.26172145182	0.12252135998098801
90	52918.3215048531	3753.909505042157	28336.11550494763	99176.4042673167	0.19176946261276306
101	36488.85817012686	2442.7132731848797	19465.78572165587	68130.25002579554	0.45927144532222464
120.25	29333.505148681335	1875.7393658423262	15604.622257261832	54616.17790041641	0.8618702078475984
142.75	12504.92654629627	902.6769423173403	6703.801744306806	23463.306105073818	0.9664560821712032


	Correlation acetate export intracellular
	TIME h	Lactate	Acetate	pH	con. H+	corLac/H
	0	4.7315E-5	5.299E-6	7.9064	1.2405092300422253E-8	3814.1594479220003
	16.839	0.52636	1.3715	7.8784	1.3231223331133686E-8	3.9781657888084345E7
	30.387	0.98531	1.8481	7.8291	1.48217676203944E-8	6.647722628198791E7
	38.129	1.3769	2.3426	7.805	1.5667510701081492E-8	8.788249941357665E7
	48.968	5.6969	3.6089	7.7583	1.7446165981330123E-8	3.26541659989736E8
	57.484	9.4358	3.7477	7.6959	2.014187980393203E-8	4.6846670180992615E8
	68.323	20.834	4.6963	7.5734	2.6705456121918948E-8	7.80140204491776E8
	76.065	34.897	5.551	7.3817	4.152407817569982E-8	8.404039664009198E8
	110.9	82.097	7.238	6.9224	1.19563879998812E-7	6.866371349007386E8
	129.48	80.202	7.3275	6.0605	8.699614330652667E-7	9.219029367475769E7
	144.19	83.697	7.6564	5.0941	8.051930173083075E-6	1.0394650500049297E7

growth CURVE b
2 biological replicates:		WT.1	WT.2
2 technical replicates:		WT.1-R1	WT.1-R2
		WT.2-R1	WT.2-R2

ug/mL Protein in 5mL					Glucose (nmol/uL=mM)			Lactate (nmol/uL=mM)			Acetate (nmol/uL=mM)
Time (h)	WT.1-R1	WT.1-R2	WT.2-R1	WT.2-R2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2
0	22.24636264931076	22.960909633202984	21.679090072891928	21.591819119453426	0	61.61898563873938	61.20286150817288	0	0.6897982831951562	0.602016479448633	0	1.290939587517829	1.154481865549625
24	60.86726996248418	69.32182035879656	60.68181715445085	63.44181998426264	24	48.35500669301099	49.538360415959076	24	8.426452892884383	8.212929682021747	24	9.651754760511832	9.42412243373152
48	84.23454485373064	78.35454447919672	80.81999849406155	77.14363602291454	48	38.51105157862404	36.75552814501315	48	13.802491353712048	15.290035210965227	48	16.935801928362025	16.801179895078505
72	78.43090778264131	79.65272714007985	90.49636174548756	88.65272505933586	72	28.706110765859584	26.898568909329462	72	38.39135739535901	37.17875503824693	72	21.80665395494053	22.394094394216985
96	77.11090982177042	78.11454366770657	72.79090821959757	73.77272676554593	96	25.28608499678586	24.15474582129244	96	43.42628840205078	52.217654509093215	96	16.776703742007317	19.652710540667055



growth CURVE C
ug/mL Protein in 5mL					Glucose (nmol/uL=mM)			Lactate (nmol/uL=mM)			Acetate (nmol/uL=mM)
Time (h)	WT.1-R1	WT.1-R2	WT.2-R1	WT.2-R2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2	Time (h)	WT.1	WT.2
0	7.639794133034185	7.678052148059931	8.084317692951288	8.472365290576326	0	47.52275843187799	49.33029835067584	0	0.9606024429530147	0.9003475342951671	0	1.00701013305017	0.9653998521854972
24	37.09636265451257	37.59817957748065	30.6054526012594	40.32545620614831	24	50.162550487273386	48.120936385134264	24	2.7682503933563987	2.6848204667018436	24	8.251078338054835	7.458034018579504
48	69.725451576493	84.5945454714515	70.32545360521837	78.53999668771569	48	41.09883102429704	39.109233407344874	48	14.503680158743649	19.47342955233663	48	15.314218566677482	16.287170042610267
72	80.55818178306926	76.30363258318468	94.07453851136293	88.53272405407645	72	28.394019605666976	30.6436918976248	72	23.284427119093518	33.2110487756053	72	21.659794604976653	21.574126701488073
96	78.11454306819222	84.50727126685055	74.32909109245647	81.11454670949415	96	19.746424273257137	21.866059227712135	96	36.612946741060206	32.891779047927606	96	24.08910317569411	25.037569380292826
144	47.21727311546152	46.65545273845846	47.1245434602824	46.633637438470664	120	18.576072733873506	18.74512437299882	120	29.595517413012537	36.63869920479326	120	16.87460683458157	20.87042111577491
192	48.13363925912164	49.26818441195922	50.713638229153375	51.308178304975684	144	15.26007799744141	16.807541303501328	144	35.89188926858808	36.80608446303138	144	16.06687919401188	18.83886029050994
240	53.89363922791047	54.41727145086635	52.04454709118063	51.308178304975684	168	16.06631995371321	15.533160669208351	168	35.351095204896204	40.321236283650684	168	15.387650673196191	22.21663688947869
					192	14.258778097183093	11.163849547330985	192	37.03785279927773	43.772008863612925	192	16.195381049244745	21.35383676471597
					216	14.869960171736109	10.38361486478652	216	35.04207331480184	42.43290377360092	216	14.757379929480598	18.643048330461596
					240	12.178153568886037	11.189856821058322	240	34.84893175547949	40.630262011096214	240	13.031774208997435	17.82307759831173

100

table S14: Alignment of gene IDs and gene names.
MPN ID	gene name
MPN001	dnaN
MPN002	xdj1
MPN003	gyrB
MPN004	gyrA
MPN005	serS
MPN006	tmk
MPN007	holB
MPN008	thdF
MPN009	yabD
MPN010	mpn010
MPN011	mpn011
MPN012	mpn012
MPN013	mpn013
MPN014	MPN014
MPN015	rimK
MPN016	rimK
MPN017	mtd1
MPN018	pmd1
MPN019	msbA
MPN020	hepA
MPN021	dnaJ
MPN022	pip
MPN023	metS
MPN024	rpoE
MPN025	tsr
MPN026	engD
MPN027	rimL
MPN028	trsB
MPN029	efp
MPN030	nusB
MPN031	mpn031
MPN032	yfkM
MPN033	upp
MPN034	polC
MPN035	mpn035
MPN036	mpn036
MPN037	mpn037
MPN038	mpn038
MPN039	mpn039
MPN040	mpn040
MPN041	mpn041
MPN042	mpn042
MPN043	glpF
MPN044	tdk
MPN045	hisS
MPN046	aspS
MPN047	pncB
MPN048	mpn048
MPN049	mpn049
MPN050	glpK
MPN051	glpD
MPN052	mpn052
MPN053	ptsH
MPN054	mpn054
MPN055	potA
MPN056	potB
MPN057	potI
MPN058	potD
MPN059	Gcp
MPN060	metX
MPN061	ffh
MPN062	deoD
MPN063	deoC
MPN064	deoA
MPN065	cdd
MPN066	cpsG
MPN067	nusG
MPN068	secE
MPN069	rpmG2
MPN070	mpn070
MPN071	yabC
MPN072	rnmV
MPN073	prs
MPN074	smpB
MPN075	ywdF
MPN076	uhpT
MPN077	uhpT
MPN078	fruA
MPN079	fruK
MPN080	ftsX
MPN081	glnQ
MPN082	tklB
MPN083	mpn083
MPN084	mpn084
MPN085	mpn085
MPN086	mpn086
MPN087	mpn087
MPN088	mpn088
MPN089	hsdS
MPN090	mpn090
MPN091	mpn091
MPN092	mpn092
MPN093	mpn093
MPN094	mpn094
MPN095	mpn095
MPN096	mpn096
MPN097	mpn097
MPN098	mpn098

100

model_ID	reaction_ID (Yus2009)	equation	gene number	enzyme (short)	EC number	pathway	reversi-bility
M001	R001/R002	D-glucose[e] + phosphoenolpyruvate[c] --> D-glucose 6-phosphate[c] + pyruvate[c]	MPN627/MPN207	PTSI/G	2.7.3.9/2.7.1.69	Glycolysis	I
M002	R003	[c]: D-glucose 6-phosphate <==> D-fructose 6-phosphate	MPN250	PGI	5.3.1.9	Glycolysis	R
M003	R004	[c]: D-fructose 6-phosphate + ATP --> ADP + D-fructose 1,6-bisphosphate + H+	MPN302	PFK	2.7.1.11	Glycolysis	I
M004	R005	[c]: D-fructose 1,6-bisphosphate <==> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate	MPN025	FBA	4.1.2.13	Glycolysis	R
M005	R006	[c]: D-glyceraldehyde 3-phosphate <==> dihydroxyacetone phosphate	MPN629	TIM	5.3.1.1	Glycolysis	R
M006	R007	[c]: NAD+ + orthophosphate + D-glyceraldehyde 3-phosphate <==> NADH + H+ + 1,3-bisphospho-D-glycerate	MPN430	GAPDH	1.2.1.12	Glycolysis	R
M007	R008	[c]: 3-phospho-D-glycerate + ATP <==> ADP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Glycolysis	R
M008	R009	[c]: 2-phospho-D-glycerate <==> 3-phospho-D-glycerate	MPN628	PGM	5.4.2.1	Glycolysis	R
M009	R010	[c]: 2-phospho-D-glycerate <==> phosphoenolpyruvate + H2O	MPN606	ENO	4.2.1.11	Glycolysis	R
M010	R011	[c]: ADP + phosphoenolpyruvate + H+ --> ATP + pyruvate	MPN303	PYK	2.7.1.40	Glycolysis	I
M011	R012	[c]: (S)-lactate + NAD+ <==> NADH + H+ + pyruvate	MPN674	LDH	1.1.1.27	Pyruvate metabolism	R
M012	R015	[c]: lipoamide + H+ + pyruvate --> S-acetyldihydrolipoamide + CO2	MPN392/MPN393	PDH-E1	1.2.4.1	Pyruvate metabolism	I
M013	R016	[c]: acetyl-CoA + dihydrolipoamide <==> S-acetyldihydrolipoamide + CoA	MPN391	PDH-E2	2.3.1.12	Pyruvate metabolism	R
M014	R017	[c]: dihydrolipoamide + NAD+ <==> lipoamide + NADH + H+	MPN390	PDH-E3	1.8.1.4	Pyruvate metabolism	R
M015	R018	[c]: acetyl-CoA + orthophosphate <==> acetyl phosphate + CoA	MPN428	PTA	2.3.1.8	Pyruvate metabolism	R
M016	R019	[c]: acetate + ATP <==> ADP + acetyl phosphate	MPN533	ACK	2.7.2.1	Pyruvate metabolism	R
M017	R020	[c]: (2) NADH + oxygen + (2) H+ <==> (2) H2O + (2) NAD+	MPN394	NOX	1.6.99.3	Pyruvate metabolism	R
M018	R190	(4) H+[e] + ADP[c] + orthophosphate[c] <==> H2O[c] + (3) H+[c] + ATP[c]	MPN597-MPN604	ATPase	3.6.3.14	Energy metabolism	R
M019	R021	D-fructose[e] + phosphoenolpyruvate[c] --> D-fructose 1-phosphate[c] + pyruvate[c]	MPN078	FRUA	2.7.1.69	Alternative sugar metabolism	I
M020	R022	[c]: D-fructose 1-phosphate + ATP --> ADP + D-fructose 1,6-bisphosphate + H+	MPN079	FRUK	2.7.1.56	Alternative sugar metabolism	I
M021	R023	[c]: D-fructose 1-phosphate --> D-glyceraldehyde + dihydroxyacetone phosphate	MPN025	FBA	4.1.2.13	Alternative sugar metabolism	I
M022	R024	[c]: glycerol + NAD+ <==> D-glyceraldehyde + NADH + H+	MPN564	ADH	1.1.1.1	Alternative sugar metabolism	R
M023	R026	D-mannose[e] + phosphoenolpyruvate[c] --> D-mannose 6-phosphate[c] + pyruvate[c]	MPN078	FRUA	2.7.1.69	Alternative sugar metabolism	I
M024	R028	[c]: D-mannose 6-phosphate <==> D-fructose 6-phosphate	?	MPI	5.3.1.8	Alternative sugar metabolism	R
M025	R029	mannitol[e] + phosphoenolpyruvate[c] --> pyruvate[c] + D-mannitol 1-phosphate[c]	MPN651/MPN653	MTLA	2.7.1.69	Alternative sugar metabolism	I
M026	R030	[c]: NAD+ + D-mannitol 1-phosphate <==> NADH + D-fructose 6-phosphate + H+	MPN652	MTLD	1.1.1.17	Alternative sugar metabolism	R
M027	R031	L-ascorbate[e] + phosphoenolpyruvate[c] + (2) H+[c] --> L-ascorbate 6-phosphate[c] + pyruvate[c]	MPN494-MPN496	PTSA	2.7.1.69	Alternative sugar metabolism	I
M028	R032	[c]: H2O + L-ascorbate 6-phosphate <==> 3-keto-L-gulonate 6-phosphate + (3) H+	MPN497	ULAG	3.1.1.-	Alternative sugar metabolism	R
M029	R033	[c]: 3-keto-L-gulonate 6-phosphate + H+ --> CO2 + L-xylulose 5-phosphate	MPN493	KGPDC	4.1.1.85	Alternative sugar metabolism	I
M030	R034	[c]: L-ribulose 5-phosphate <==> L-xylulose 5-phosphate	MPN492	ULAE	5.1.3.22	Alternative sugar metabolism	R
M031	R035	[c]: L-ribulose 5-phosphate <==> D-xylulose 5-phosphate	MPN498	ULAF	5.1.3.4	Alternative sugar metabolism	R
M032	R191	D-ribose[e] --> D-ribose[c]	MPN258-MPN260	RibABC	3.6.3.17	Pentose phosphate pathway	I
M033	R036	[c]: D-ribose + ATP --> ADP + D-ribose 5-phosphate + H+	?	RBSK	2.7.1.15	Pentose phosphate pathway	I
M034	R037	[c]: D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate <==> D-xylulose 5-phosphate + D-erythrose 4-phosphate	MPN082	TKL	2.2.1.1	Pentose phosphate pathway	R
M035	R038	[c]: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <==> D-erythrose 4-phosphate + D-fructose 6-phosphate	?	TAL	2.2.1.2	Pentose phosphate pathway	R
M036	R039	[c]: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <==> D-xylulose 5-phosphate + D-ribose 5-phosphate	MPN082	TKL	2.2.1.1	Pentose phosphate pathway	R
M037	R040	[c]: D-ribulose 5-phosphate <==> D-xylulose 5-phosphate	MPN251	RPE	5.1.3.1	Pentose phosphate pathway	R
M038	R041	[c]: D-ribose 5-phosphate <==> D-ribulose 5-phosphate	MPN595	RPIA	5.3.1.6	Pentose phosphate pathway	R
M039	R042	[c]: D-ribose 5-phosphate + ATP --> AMP + 5-phospho-alpha-D-ribose 1-diphosphate + H+	MPN073	PRPS	2.7.6.1	Pentose phosphate pathway	I
M040	R043	[c]: D-ribose 1-phosphate <==> D-ribose 5-phosphate + (2) H+	MPN066	DEOB	5.4.2.7	Pentose phosphate pathway	R
M041	R044	[c]: 2-deoxy-D-ribose 1-phosphate <==> 2-deoxy-D-ribose 5-phosphate	MPN066	DEOB	5.4.2.7	Pentose phosphate pathway	R
M042	R046	[c]: 2-deoxy-D-ribose 5-phosphate --> acetaldehyde + D-glyceraldehyde 3-phosphate	MPN063	DERA	4.1.2.4	Pentose phosphate pathway	I
M043	R047	[c]: acetaldehyde + NAD+ + CoA <==> acetyl-CoA + NADH + H+	MPN564	ADH	1.2.1.10	Alternative sugar metabolism	R
M044	R192	glycerol[c] <==> glycerol[e]	MPN043	GlpF	-	Alternative sugar metabolism	R
M045	R049	[c]: glycerol + ATP --> ADP + sn-glycerol 3-phosphate + H+	MPN050	GK	2.7.1.30	Alternative sugar metabolism	I
M046	R193	sn-glycerol 3-phosphate[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + sn-glycerol 3-phosphate[c]	MPN133-MPN136	GlyABC	-	Alternative sugar metabolism	I
M047	R186	[c]: oxygen + sn-glycerol 3-phosphate <==> H2O2 + dihydroxyacetone phosphate	MPN051	GPO	1.1.3.21	Lipid metabolism	R
M048	R051	[c]: H2O + dihydroxyacetone phosphate --> dihydroxyacetone + orthophosphate	-	-	-	Lipid metabolism	I
M049	R052	[c]: dihydroxyacetone + ATP --> ADP + dihydroxyacetone phosphate + H+	MPN547	DHAK	2.7.1.29	Lipid metabolism	I
M050	R053	[c]: ACP-R (Mpn) + sn-glycerol 3-phosphate --> 1-acyl-glycerol 3-phosphate (Mpn) + acyl carrier protein	MPN350/MPN546	GPAM	2.3.1.15	Lipid metabolism	I
M051	R054	[c]: ACP-R (Mpn) + 1-acyl-glycerol 3-phosphate (Mpn) --> phosphatidic acid (Mpn) + acyl carrier protein	MPN299	AGPAT	2.3.1.51	Lipid metabolism	I
M052	R055	[c]: phosphatidic acid (Mpn) + CTP + H+ --> CDP-diacylglycerol (Mpn) + pyrophosphate	MPN637	CDP-DG	2.7.7.41	Lipid metabolism	I
M053	R056	[c]: CDP-diacylglycerol (Mpn) + sn-glycerol 3-phosphate --> CMP + phosphatidylglycerol 3-phosphate (Mpn) + H+	MPN253	PGP	2.7.8.5	Lipid metabolism	I
M054	R057	[c]: H2O + phosphatidylglycerol 3-phosphate (Mpn) --> orthophosphate + phosphatidylglycerol (Mpn)	?	PGPB	3.1.3.27	Lipid metabolism	I
M055	R058	[c]: CDP-diacylglycerol (Mpn) + phosphatidylglycerol (Mpn) --> cardiolipin (Mpn) + CMP + H+	?	CLS	2.7.8.-	Lipid metabolism	I
M056	R059	[c]: H2O + phosphatidic acid (Mpn) --> diacylglycerol (Mpn) + orthophosphate	MPN455	PPT	3.1.3.4	Lipid metabolism	I
M057	R060	[c]: D-glucose 1-phosphate <==> D-glucose 6-phosphate	MPN066	PGM	5.4.2.2	Lipid metabolism	R
M058	R061	[c]: D-glucose 1-phosphate + UTP + H+ <==> UDP-glucose + pyrophosphate	MPN667	UGP	2.7.7.9	Lipid metabolism	R
M059	R062	[c]: UDP-glucose <==> UDP-galactose	MPN257	UGE	5.1.3.2	Lipid metabolism	R
M060	R063/R064	[c]: diacylglycerol (Mpn) + (3) UDP-galactose + (3) UDP-glucose --> glycolipid (Mpn) + (6) H+ + (6) UDP	MPN483	GTF	-	Lipid metabolism	I
M061	R178	[c]: choline + ATP --> ADP + H+ + choline phosphate	MPN532	CHK	2.7.1.32	Lipid metabolism	I
M062	R180	[c]: CTP + H+ + choline phosphate --> CDP-choline + pyrophosphate	MPN336	PCT	2.7.7.15	Lipid metabolism	I
M063	R182	[c]: sn-glycero-3-phosphocholine + H2O <==> choline + sn-glycerol 3-phosphate + H+	MPN420	GlpQ	3.1.4.46	Lipid metabolism	R
M064	R187	[c]: phosphatidylcholine + (2) H2O <==> sn-glycero-3-phosphocholine + (2) fatty acid (Mpn)	MPN445	PldB	3.1.1.5	Lipid metabolism	R
M065	R065	[c]: AMP + pyrophosphate <==> adenine + 5-phospho-alpha-D-ribose 1-diphosphate	MPN395	APRT	2.4.2.7	Nucleotide metabolism	R
M066	R066	[c]: adenosine + orthophosphate + (2) H+ <==> D-ribose 1-phosphate + adenine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M067	R067	[c]: H2O + AMP --> adenosine + orthophosphate	?	NT5	3.1.3.5	Nucleotide metabolism	I
M068	R068	[c]: AMP + ATP <==> (2) ADP	MPN185	AK	2.7.4.3	Nucleotide metabolism	R
M069	R069	[c]: ADP + reduced thioredoxin --> dADP + H2O + oxidized thioredoxin	MPN322-MPN324	RDR	1.17.4.1	Nucleotide metabolism	I
M070	R070	[c]: oxidized thioredoxin + H+ + NADPH <==> NADP+ + reduced thioredoxin	MPN240	TXNRD	1.8.1.9	Nucleotide metabolism	R
M071	R071/R084/R099/R104	[c]: (28) GTP + (25) UTP + (40) H2O + (18) CTP + (69) ATP --> (40) ADP + RNA (Mpn) + (40) orthophosphate + (40) H+ + (100) pyrophosphate	MPN516	RNAP	-	Nucleotide metabolism	I
M072	R072	[c]: H2O + pyrophosphate --> (2) orthophosphate + H+	MPN528	PPA	3.6.1.1	Nucleotide metabolism	I
M073	R073	[c]: deoxyadenosine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + adenine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M074	R074	[c]: deoxyadenosine + ATP <==> ADP + H+ + dAMP	MPN386	DAK	2.7.1.76	Nucleotide metabolism	R
M075	R075	[c]: dAMP + ATP <==> dADP + ADP	MPN185	AK	2.7.4.3	Nucleotide metabolism	R
M076	R076	[c]: phosphoenolpyruvate + dADP + H+ --> dATP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M077	R175	[c]: 3-phospho-D-glycerate + dATP <==> dADP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Nucleotide metabolism	R
M078	R077/R089/R110/R120	[c]: (20) dGTP + (140) H2O + (30) dTTP + (20) dCTP + (140) ATP + (30) dATP --> (140) ADP + DNA (Mpn) + (140) orthophosphate + (140) H+ + (100) pyrophosphate	MPN034/MPN378	DNAP	-	Nucleotide metabolism	I
M079	R078	[c]: GMP + pyrophosphate <==> 5-phospho-alpha-D-ribose 1-diphosphate + guanine	MPN672	HPRT	2.4.2.8	Nucleotide metabolism	R
M080	R079	[c]: guanosine + orthophosphate + (2) H+ <==> D-ribose 1-phosphate + guanine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M081	R080	[c]: GMP + H2O --> guanosine + orthophosphate	?	NT5	3.1.3.5	Nucleotide metabolism	I
M082	R081	[c]: GMP + ATP <==> ADP + GDP	MPN246	GUK	2.7.4.8	Nucleotide metabolism	R
M083	R082	[c]: reduced thioredoxin + GDP --> H2O + oxidized thioredoxin + dGDP	MPN322-MPN324	RDR	1.17.4.1	Nucleotide metabolism	I
M084	R083	[c]: phosphoenolpyruvate + H+ + GDP --> GTP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M085	R176	[c]: GTP + 3-phospho-D-glycerate <==> GDP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Nucleotide metabolism	R
M086	R085	[c]: deoxyguanosine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + guanine	MPN062	PNP	2.4.2.1	Nucleotide metabolism	R
M087	R086	[c]: deoxyguanosine + ATP <==> ADP + H+ + dGMP	MPN386	DGK	2.7.1.113	Nucleotide metabolism	R
M088	R087	[c]: ATP + dGMP <==> ADP + dGDP	MPN246	GUK	2.7.4.8	Nucleotide metabolism	R
M089	R088	[c]: phosphoenolpyruvate + dGDP + H+ --> dGTP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M090	R177	[c]: 3-phospho-D-glycerate + dGTP <==> dGDP + 1,3-bisphospho-D-glycerate	MPN429	PGK	2.7.2.3	Nucleotide metabolism	R
M091	R090	[c]: UMP + pyrophosphate <==> uracil + 5-phospho-alpha-D-ribose 1-diphosphate	MPN033	UPRT	2.4.2.9	Nucleotide metabolism	R
M092	R091	[c]: orthophosphate + (2) H+ + uridine <==> uracil + D-ribose 1-phosphate	MPN064	UPP	2.4.2.3	Nucleotide metabolism	R
M093	R092	[c]: H2O + UMP --> orthophosphate + uridine	?	NT5	3.1.3.5	Nucleotide metabolism	I
M094	R093	[c]: ATP + uridine --> ADP + UMP + H+	MPN561	UCK	2.7.1.48	Nucleotide metabolism	I
M095	R094	[c]: UMP + ATP <==> ADP + UDP	MPN632	UMPK	2.7.4.22	Nucleotide metabolism	R
M096	R095	[c]: phosphoenolpyruvate + H+ + UDP --> UTP + pyruvate	MPN303	PYK	2.7.1.40	Nucleotide metabolism	I
M097	R096	[c]: reduced thioredoxin + UDP --> H2O + oxidized thioredoxin + dUDP	MPN322-MPN324	RDR	1.17.4.1	Nucleotide metabolism	I
M098	R097	[c]: cytidine + H2O --> NH3 + uridine	MPN065	CDA	3.5.4.5	Nucleotide metabolism	I
M099	R100	[c]: cytidine + ATP --> ADP + CMP + H+	MPN561	UCK	2.7.1.48	Nucleotide metabolism	I

aa		aa in proteome	aa in cytosol	times enrichment	import/min during exp growth	min for intracellular pool tunrover
L	Leu	2393036	25097.05592913839	95.3512637799726	1994.1966666666667	12.585045571803377
E	Glu	1672072	98709.27690427659	16.93936023481859	1393.3933333333334	70.84092807315228
A	Ala	2032737	38012.458206949574	53.47554712019039	1693.9475	22.440163114234398
V	Val	1864124	12050.334305584664	154.69479540796488	1553.4366666666667	7.75720991023215
I	Ile	1724690	17162.645565208353	100.49091752475763	1437.2416666666666	11.941377684250517
S	Ser	1515135	12566.026347110956	120.57391558377111	1262.6125	9.952401348086571
G	Gly	1588085	34936.658649543664	45.4561214891895	1323.4041666666667	26.39908467081573
D	Asp	1305481	23289.714936892153	56.053970756509706	1087.9008333333334	21.407939237928844
T	Thr	1533247	6433.410380326506	238.32569498266412	1277.7058333333334	5.035126405850986
F	Phe	1102859	39005.54349337493	28.27441694761464	919.0491666666666	42.44119347264693
R	Arg	907229	38302.24724840229	23.686051476727478	756.0241666666666	50.66272870254671
P	Pro	974850	35012.34123028322	27.843039503934204	812.375	43.09874285925
N	Asn	1473974	13655.645188364413	107.93880330575162	1228.3116666666667	11.117410636847932
M	Met	469166	12369.476786726444	37.92933267019484	390.97166666666664	31.637783096114667
Q	Gln	1179691	7692.708238618437	153.35184481296088	983.0758333333334	7.825142250252077
K	Lys	2149849	24800.00990495273	86.68742505504648	1791.5408333333332	13.842838211401489
H	His	478238	12279.469738303413	38.94614427105348	398.5316666666667	30.811779252096432
C	Cys	197940	3627.5517146154225	54.56572795433869	164.95	21.991826096486346
Y	Tyr	748700	5417.454387835065	138.20144045535696	623.9166666666666	8.682977514895256
W	Trp	211534	6470.8277604091345	32.69040806405659	176.27833333333334	36.708015319007636

sum		25522637	466890.8569169164	80.57381106984371
average					1063.4432083333334	24.35898567139502

100

Growth Curve A
	Mol Syst Biol. 2011 Jul 19;7:511. doi: 10.1038	Mol Syst Biol. 2011 Jul 19;7:511. doi: 10.1038	Mol Syst Biol. 2011 Jul 19;7:511. doi: 10.1038	Mol Syst Biol. 2011 Jul 19;7:511. doi: 10.1038	Mol Syst Biol. 2011 Jul 19;7:511. doi: 10.1038		UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA	UNPUBLISHED DATA
time	24h	48h	72h	96h	96h	A	0h old	0h Old	0.25 h Old	0.25 h Old	0.25	0.25	0.5 h Old	0.5 h Old	1h	1h	1h Old	1h Old	2h	2h	2h sira	2h Sira	2h Old	2h Old	6h average	6h Glucose	6h	6h	6h Old	6h Old	8h	8h	8h Old Maria	8h Old Maria	10h	10h	10h old maria	10h old maria	12h	12h	12h Old MAria	12h Old Maria	24h	24h	24h Old	24 h Old	24h sira	24h sira	36h	36h	36hOld Maria	36h Old Maria	48h	48h	48h old	48h Old	72h	72h	72h Old	72h Old	96h	96h	96h maria old	96h maria old	96h Old	96h Old
MPN	(copies/cell)	(copies/cell)	(copies/cell)	(copies/cell)	(copies/cell)	MPN001	328.24	340.46	337.9	350.5	365.23	368.74	357.1	350.7	393.89	369.42	337.6	343.6	404.13	407.73	484.87	470.74	343.7	328.6	452.88	417.96	453.09	458.37	322.5	327.2	404	411.04	448.4	436.9	450.08	462.28	354.3	337.6	448.53	448.35	309.5	309.4	332.31	347.67	269.6	293.2	318.83	309.98	322.01	322.04	295.1	306.9	380.36	376.63	373.1	385.7	531.59	538.39	341.9	348.3	431.84	429.17	404.71	399.05	357.8	345.1
MPN001	477.5656118839428	318.3770746301146	226.6962687159911	347.8564335369969	265.903816	MPN002	18.84	18.5	23.5	23.2	9.83	9.95	27.2	26.2	9.92	6.01	23.2	19.1	8.14	5.05	6.58	8.52	27.2	24.9	13.01	16.12	6.95	7.51	24.5	24.7	10.31	7.7	5.8	4.9	7.97	8.4	9.3	9.7	7.47	6.33	26.1	27	9.57	8.01	22	25.1	9.75	11.25	12.77	13.26	18.7	9.4	5.48	11.17	27.6	26.6	8.89	11.83	23.8	27.2	2.59	0	7.25	10.16	23.4	21.8
MPN003	132.87853502283994	154.00763098601448	90.15080838374476	111.2799040201361	96.25476929	MPN003	120.51	113.63	126.8	119.9	101.21	100.3	118	130.7	134.77	146.21	115.2	126.7	88.69	93.66	89.65	93.91	101	105.2	89.37	103.41	84.27	81.54	105	105.5	78.99	71.66	106.3	108.9	90.67	92.3	98.7	113.5	109.75	106.78	123.9	119.1	135.22	121.61	122.1	133	119.02	116.12	125.84	120.04	128.7	147.7	93.55	111.13	103.2	104	71.77	76.49	115.3	105.9	49.96	54.35	105.58	116.56	126.9	107.2
MPN004	176.8436866562188	159.50607010301752	145.6359771457081	139.39443536863587	106.1062119	MPN004	111.31	109.2	117.5	115.4	166.49	100.98	109.2	102.5	115.23	107.3	105.6	90	101.76	100.53	82.53	78.25	94.1	97.4	89.56	91.1	96.59	120.18	89	83.6	83.21	85.21	83.3	101.9	124.91	85.99	86.9	71.1	90.25	97.22	115.2	109.6	130.55	129.68	128.4	129.3	152.38	160.38	179.17	161.57	124.2	142.3	107.87	107.59	108.1	89.4	84.64	108.16	106.7	99.8	69.83	57.68	101.18	98.58	106.2	112.4
MPN005	145.4720498255171	58.18881988626488	123.20225459235076	79.02185411566258	80.45861519	MPN005	96.6	96.6	102.5	102.6	100.69	98.9	105.7	105	117.42	116.87	103.9	102.5	94.64	112.59	92.14	108.7	95.3	100.5	85.49	79.67	100.67	107.69	75	74.8	72.16	74.91	127.3	96.6	86.3	118.19	115.9	101.4	108.53	113.86	83.9	83.3	108.93	113.36	81.7	91.6	93.38	99.27	106.23	73.33	87.4	84.3	106.82	101	74.9	73.2	77.57	87.88	96.1	92	103.53	106.83	80.66	82.32	102.1	95.6
MPN006	24.986611591351114	24.871465955765473	11.111557702155242	19.74748337581412	18.65359945	MPN006	17.56	41.49	22.2	46.5	35.98	11.69	39.6	29.8	23.16	23.18	38	38.4	31.26	26.42	17.36	11.85	37.4	38.2	22.04	23.07	31.28	30.77	34	34.6	25.84	24.1	17.3	19.6	26.76	18.26	28.1	31.2	12.77	27.23	38.8	34	54.78	27.5	41.4	41.1	45.35	26.76	46.06	39.67	34.1	45.7	43.98	30.18	37.1	36.2	29.82	28.73	38.2	38	27.56	20.1	27.57	27.08	34.6	33.9
MPN007	0.7444823575350148	0.9502887774932081	2.2012338946228036	2.6128467346308835	2.7381202079999998	MPN007	15.71	16.95	20.3	21.6	4.82	4.52	17.9	13.6	4.45	4.79	26.5	23	6.83	6.7	5.85	5.11	21.9	18.1	6.66	15.34	8.21	7.26	18.9	18.3	8.55	5.47	10.7	6.3	5.61	5.89	9.7	9.4	4.33	4.26	24.2	21	9.02	6.44	18.1	18.1	6.09	7.76	9.62	11.59	8.2	7.8	8.47	7.85	21.5	20.5	9.1	6.57	24	23.5	4.03	2.94	8.66	8.93	17.9	17.5
MPN009	4.470862219858344	15.306493565740109	3.058193946166992	3.6636232061605702	3.291051355	MPN008	20.99	18.71	25.7	23.4	11.17	9.81	26.8	13.6	7.86	9.52	34.5	26.7	9.68	11.27	7.89	6.27	18.3	20.1	4.88	1.66	8.02	7.16	16.5	16.4	11.99	12.07	5.3	8.1	7.55	7.35	9.7	9.4	7.67	7.37	19.8	19.4	16.71	15.2	19	25.9	20.52	18.65	20.61	23.77	12.2	12.6	13.38	12.45	16.7	22.3	4.72	3.74	21.8	15.7	4.6	4.72	4.13	3.83	11.9	18.2
MPN015	51.189313044796755	40.08801621527551	35.92502991143064	42.70915572783576	42.86334042	MPN009	0	13.95	0	18.5	3.75	0	18.8	18.8	2.21	0	17.6	18.7	2.56	2.54	0	0	0	0	3.26	3.89	2.78	0.56	17.8	16.6	2.76	0	3.8	6.2	0.47	0	3.8	6.3	2.89	0	20	16.8	3.72	5.15	16.1	18.9	6.26	6.53	8.13	6.29	6.6	7.1	2.86	3.4	17.4	17.6	1.25	1.33	16.4	16.5	0	1.85	1.86	1.92	14	12.6
MPN017	22.515835679725022	15.96690838952504	28.19157265774224	19.210186692038274	13.40970823	MPN010	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN018	8.78177921627545	10.848080224435359	7.8132006272123755	17.305270822147662	13.23724074	MPN011	0	12.97	0	17.5	17.39	13.64	21.2	13.6	4.45	1.44	19.1	18.2	26.34	1.63	0	8.11	22.3	20.5	12.67	0	4.15	3.17	0	27.4	36.08	40.43	0	2.9	5.85	14.67	2.5	7.1	0	1.8	16.8	0	3.33	13.75	14.9	15.7	42.65	27.25	0	0	3.4	3	19.15	18.21	0	14.3	26.82	0	19.8	22.6	21.41	18.77	5.29	4	25.1	24.9
MPN019	10.154115678693563	26.214873822543762	80.96745837961363	42.93929964945863	33.38248486	MPN012	0	0	0	0	67.56	68.19	0	0	58.32	57.36	0	0	0	45.72	38.46	0	0	0	20.1	11.8	40.06	43.2	0	0	0	15.07	0	60.3	43.21	0	0	0	40.92	0	0	0	49.09	48.4	0	0	49.3	0	0	0	0	51.5	0	21.82	0	0	0	0	0	0	0	0	13.27	9.8	0	0
MPN020	55.0959255577953	51.4532197160105	52.81923442993232	50.08720495545923	44.48654481	MPN013	0	0	0	0	0	0	13.6	13.6	0.26	0	0	0	0.47	0	0	0	0	0	5.71	6.42	0	0	0	15.9	1.87	0	1.4	0	0	0	1.8	2.8	0	0	0	0	0	0	0	0	2.6	0	2.55	1.92	0	0	0	0	0	14	3.23	0	16.6	0	0	0	4.76	4.3	0	0
MPN021	60.6714364591427	74.76101180687176	52.62025052587708	54.201733488719675	73.75461349	MPN014	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN022	16.046882645144255	40.49414685440899	44.58664039964356	37.80171683054451	36.40165326	MPN015	32.76	33.12	37.6	38	27.29	27.85	36.1	38	22.96	15.25	37.8	39	23.29	22.56	16.99	14.38	26.1	27.6	16.01	20.17	23.15	20.17	41.6	41.9	21.19	18.34	18	17.2	22.95	21.58	21.7	16.8	18.97	19.16	35	30.6	21.19	10.94	29.5	24.1	28.48	25.62	22.43	16.82	20.5	23.4	24.49	24.84	31.4	37.9	3.05	3.16	19.5	19.4	5.2	7.51	16.74	12.57	25.4	22.4
MPN023	23.889306214499264	22.850640737192712	38.875765366768256	55.346032438428516	24.48282934	MPN016	0	0	0	0	0	0	13.6	13.6	0	0	0	0	0	0	0	0	0	0	1.21	1.34	0	0	0	0	0	0	0	0	0	0	0.6	0	0	0	0	0	0	0	0	0	1.74	0	1.52	0	0	0	2.06	0	15.1	14.2	1.98	0	14.9	15.5	0	0	0.93	1.27	10.4	99.6
MPN024	202.8922681391871	162.4608380362496	63.22005468471624	54.39865164440194	43.73945639	MPN017	35.82	34.17	40.8	39.1	15.85	13.15	20.1	41	12.29	12.83	47	45.2	19.99	17.4	7.1	14.61	32	30.8	5.57	0	18.67	16.9	29.5	27.5	19.82	14.95	13.3	12	16.15	15.2	19.3	15.9	14.88	14.37	27.5	28.4	17.25	17.6	29.8	27.6	18.65	17.83	25.55	22.82	27.8	27.7	19.18	18.71	27.7	25.6	6.34	8.32	26.5	26.1	9.82	9.41	5	7.44	20.4	12.7
MPN025	569.5313189734233	965.7270191090435	827.0585244668042	970.6794653743888	1198.491994	MPN018	31.8	31.8	36.7	36.7	57.86	58.11	46.6	53.9	11.93	13.9	42.5	29.5	24.18	23.54	26.8	25.71	42.9	41.9	16.4	15.2	51.68	48.82	30.7	37	23.46	22.2	28.7	17.6	25.88	20.19	7.9	18.1	20.82	19.27	34	21.3	12.18	19.17	25.2	26.6	12.01	9.25	13.9	13.52	9.7	11.1	14.41	11.32	33.7	31.8	10.01	10.35	45.8	44.6	17.8	27.83	36.61	38.11	41.3	41
MPN029	314.4990616576042	313.12269844683635	90.1518098827756	163.7872574984872	147.9590772	MPN019	35.41	36.9	40.3	41.9	52.06	36.16	40.8	41.2	15.44	14.24	26.6	34.5	14.93	15.77	16.47	18.26	37	42.6	21.67	18.88	17.01	18.41	31.8	30.5	10.89	13.93	13.7	12.4	20.49	21.87	9.5	13	13.9	14.01	28.3	49.7	8.85	11.5	25.9	29.5	10.66	13.72	7.87	6.97	8.2	7.1	12.16	12.17	28.9	26.4	3.75	3.7	46.6	49.1	11.51	13.27	26.22	27.02	48.6	51
MPN030	32.15115739935305	53.70915881492679	39.58495098945004	34.00960575682596	45.34614105	MPN020	61.25	74.52	66.6	80.1	51.56	46.28	86	84	53.51	50.75	76.8	71.8	44.99	41.52	48.17	44.91	60.9	75.1	54.23	90.76	46.59	46.78	55.4	56.5	38.15	37.24	72.9	72	48.15	45.06	67.7	65.1	44.15	46.74	57.2	51.2	42.98	48.92	56.9	64.7	57.09	49.74	56.27	53.29	54.8	49.3	53.31	51.64	94.2	57.9	23.71	25.06	75.1	60.3	33.35	39.67	53.89	51.83	71.9	70.8
MPN033	12.034301210753718	10.717571053454781	6.430542641199178	15.831383536875917	13.32040975	MPN021	116.65	119.56	122.9	125.9	59.45	54.6	111.9	116.4	63.42	61.84	122.8	119.8	87.24	66.49	60.37	62.7	101.9	98.1	144.79	109.91	63.34	78.87	90.1	87.1	77.56	105.34	63.8	67.8	66.72	62.93	61.6	74	58.88	60.58	89.6	89.8	80.16	71.91	76.4	85.2	81.16	74.57	59.54	119.88	84.5	112.1	79.49	76.97	104.9	109	109.78	137.61	119.2	103.4	74.77	87.62	106.76	107.7	113.7	116.4
MPN034	10.64894531563004	9.263716651443012	55.8420302884846	77.05334411728302	69.86747044	MPN022	54.57	56.82	59.8	62.1	35.31	31.99	81	58.9	26.03	20.22	59.8	47.5	34.84	32.86	36.24	32.9	49.4	59.2	80.98	93.47	39.68	36.19	49.1	42.7	44.37	42.62	22.2	25	34.35	30.79	19.5	28.5	33.82	28.24	47.9	41.1	32	29.73	48.1	36.2	38.84	37.5	18.81	40.58	33.8	33.7	36.36	33.64	70.2	69.4	40.62	38.2	90.2	89.1	35.29	30.36	112.66	109.18	92.7	97.2
MPN036	154.2943596731644	16.022875805270896	170.61395538628537	12.892480625933155	13.93100036	MPN023	23.38	24.22	28.1	29	3.84	13.49	30.3	29.6	19.54	20.96	29.1	29.8	6.41	12.08	11.77	11.42	20.5	21.3	17.19	15.5	11.39	10.46	24.1	23.3	14.52	6.48	11.5	12.7	10.42	11	16.1	14.5	11.85	13.28	29.1	27.6	22.02	23.87	23.2	31.2	24.13	25.07	19.78	34.82	28.5	35.5	8.9	16.48	26.4	27.7	2.8	2.16	27.1	26.6	12.23	11.06	12.03	20.87	25.8	23.1
MPN044	44.15967652643305	43.86851380847804	118.89143679004344	136.36119876089842	74.24648902	MPN024	178.16	183.32	185.4	190.7	167.36	146.44	175.8	163.4	243.08	245.21	211.5	206.4	158.51	155.34	155.3	144.9	153.3	175.9	188.5	147.56	148.22	137.63	189.4	188.8	148.69	139.04	161.5	169.4	154.37	145.53	166.6	189.7	178.9	180.22	205.4	205.3	210.85	199.95	184.2	193.9	194.66	186.81	211.46	195.58	179.7	240.6	178.62	175.86	189.2	181.3	192.72	177.12	184.4	179	137.07	116.25	163.14	166.39	147.2	145.7
MPN045	5.568577679582785	15.014751342141237	11.516168516134853	9.25666709837949	11.00595851	MPN025	672.53	705.02	687.9	721.2	555.05	487.34	652.1	611.2	448.75	366.89	720.1	687.4	619.82	645.15	672.89	696.33	661.7	658.3	642.15	696.87	654.7	658.71	604.4	614.3	670.86	648.19	566.3	653.8	693.28	669.28	594.8	642.4	616.6	596.79	616.8	716.3	517.48	498.73	616.5	640.3	460.1	529.74	593.18	562.44	617.1	667.5	532.95	530.86	568.2	603.7	764.33	720.71	587.3	604.8	477.96	478.66	500.28	507.68	697	653
MPN046	45.06662164979766	18.669217058205017	12.156699486405753	4.42851195148242	3.499392777	MPN026	25.49	25.08	30.3	29.9	16.79	16.8	13.6	13.6	19.35	19.75	0	0	15.82	17.37	13.81	14.38	0	23.7	13.45	15.81	9.29	13.62	23.9	35.8	9.97	10.89	18.6	17.2	13.82	15.09	17.2	17.5	13.86	15.56	26.9	27.2	23.02	24.86	21.8	28.9	21.76	21.58	9.69	20.51	23.9	6	19.96	19.29	25.3	32.2	10.65	8.6	21.7	23.2	10.21	7.38	12.38	12.21	16.3	16.2
MPN050	100.10180643251684	174.23863928565564	432.18015488982354	257.9415152993262	223.777076	MPN027	20.11	20.99	24.8	25.7	8.08	8.58	25.5	24.4	1.84	1.83	24.6	24.8	6.86	6.89	5.89	0	22.5	25.7	18.47	2.49	11.94	5.72	20.7	21.2	0	6.74	5.3	7	5.12	5.41	7.9	10	10.13	1.82	20.6	27.3	8.26	6.46	19.7	24.8	8.19	10.92	11.07	8.85	12.5	0	7.31	6.47	18.2	16	7.74	6.16	19.4	22.9	7.37	8.36	5.72	11.44	15.9	18.4
MPN051	27.76299457680944	44.993524391388235	48.53670378247932	70.3782204465169	61.64161381	MPN028	0	0	0	0	4.38	0	13.6	13.6	2.27	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	2	0	0	0	0	0	1.67	0	0	0	0	14.2	0	6.62	10.06	0	0	0	0	4.18	0	0	0	0	0	0	0	0	0	0	0	0	0
MPN052	178.31028642700238	161.66799291006134	498.0800668552742	647.8607070218222	392.2826303	MPN029	229.64	237.37	237.7	245.7	132.82	128.92	234.2	242	159.4	151.48	206.4	249.5	262.89	149.78	155.6	105.51	234.4	225.6	313.89	242.88	166.92	153.18	225.3	217	315.89	311.75	198.2	180.2	149.1	143.46	203.6	249	112.77	121.39	207.6	164.8	194.31	149.76	229.3	247.7	335.47	237.23	345.28	356.6	270.2	425.3	329.24	184.71	284.2	243.7	490.14	331.82	293.9	313.5	297.26	187.58	307.43	297.82	275.1	290.7
MPN053	266.6917557219022	923.8202410861368	665.6626222659484	682.730894157828	751.0039833	MPN030	21.93	17.83	26.6	22.5	7.12	21.19	29.8	31.2	13.45	8.43	24.9	25.7	10.33	6.09	0	3.23	22.9	0	2.81	1.25	4.13	5.14	23.3	30.6	4.24	3.48	8.5	9.2	7.47	5.79	14.5	9.3	5.62	3.7	23.5	15.5	10.34	13.19	20.2	19.4	7.73	7.03	5.61	6.15	26.7	8.1	10.64	19.98	23.3	21.3	6.95	4.87	22.8	31.7	7.92	10.12	9.32	8.96	23.8	12.1
MPN055	46.881381169737466	43.223968489057285	50.206301861946535	42.558984325036775	33.01646207	MPN031	0	15.56	0	20.2	37.64	31.27	13.6	13.6	5.72	7.04	18.3	0	15.32	12.75	20.43	18.66	0	0	6.4	6.72	19.14	11.74	22.9	22.2	2.8	1.44	12.6	11.3	29.41	22.25	4.2	3.4	14.09	11.43	19.2	20.2	19.95	16.05	17.6	16.6	12.51	10.3	11.65	15.37	6.8	0	13.3	13.04	22.9	0	0	0	20.3	22.3	12.44	9.69	9.42	9.4	16.8	15.5
MPN058	12.43357884533784	15.097917145002588	9.7692405105398	14.209804395401889	11.22251596	MPN032	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN059	11.714011994070487	13.10381003029087	22.832396274798093	17.471746722812657	11.51546942	MPN033	35.26	33.29	40.2	38.2	19.56	12.32	27.7	33.7	22.3	24.29	38.1	22.6	20.7	22.9	21.11	15.44	40.2	30.1	36.48	30.75	22.69	20.92	35.9	35.6	29.47	30.5	26.4	20.8	15.58	13.01	27.3	24.5	25.32	22.78	29.8	34.7	26.86	25.23	27.2	32.2	30.22	30.12	16.72	15.04	33.7	16.9	29.73	24.72	35.7	35.9	39.46	32.3	30.6	37.4	25.93	21.28	34.51	29.06	30.2	29.7
MPN060	55.120390009324844	45.313694858376465	65.26524712579385	63.23627563557069	47.00450438	MPN034	56.82	58.76	62.1	64.1	39.25	40.62	68.9	68.9	33.12	35.14	58.8	63.2	40.38	39.04	41.04	40.68	62.1	73.3	44.57	59.66	44.38	43.6	53.9	56.5	37.75	36.24	41.8	43	44.11	44.89	40.5	40.5	38.3	41.96	50.4	43.7	30.24	33.09	51.7	52.7	39.72	36.57	41.79	45.33	45.4	52.4	38.72	36.85	60.2	67.7	24.37	23.86	73.3	55.8	24.73	25.86	47.64	45.99	67.4	65.4
MPN061	66.66212986122078	95.41834273758397	79.07958532263162	130.71005858088932	141.8204135	MPN035	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN062	842.4144681838887	477.96565533676346	524.567306835782	497.0842823528352	426.5843476	MPN036	15.49	17.07	20.1	21.7	21.73	22.63	19.8	19	18.78	19.79	24.8	23.4	23.55	23.53	13.6	12.95	23.8	25.9	7.66	8.11	19.39	20.01	15.8	15.4	7.52	9.05	19.5	18.8	15.63	16.57	22.9	20	15.52	14.06	24.4	24.1	18.59	18.43	16.5	24.7	11.59	12.3	20.55	21.35	14.1	22	13.91	15.12	15	0	0	0	16.5	15.8	7.31	9.86	9.32	7.06	10.5	10.2
MPN063	218.06918450928185	228.40421727264922	154.508735222625	167.94427716281905	163.2935127	MPN037	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN064	104.97830146683535	92.70261298589116	107.51809913403667	143.49856551741541	149.4247599	MPN038	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2.64	0	0	0	0	0	0	0	0
MPN065	24.923466393144565	30.9558977527769	18.414790463811794	17.779797671050627	21.43100613	MPN039	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN066	57.74823179839124	138.85138243551563	114.45072103076258	121.42233856960901	80.17360149	MPN040	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN067	326.759956273064	285.86114720585016	138.1949220561611	183.82938245978875	303.0816984	MPN041	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN070	18.944233138855882	18.77658504990646	17.04422154996804	19.894238941025282	9.891236768	MPN042	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN071	31.926182459290178	26.950673537462208	13.26802387468161	29.282943350369933	15.44480905	MPN043	0	0	0	0	38.38	37.21	13.6	13.6	27.93	26.82	0	0	26.36	38.1	35.65	33.39	0	0		0	0	25.52	0	63.2	40.38	40.93	12.8	11.6	0	13.53	7.1	0	41.1	41.32	29	0	21.76	21.78	49.1	66.1	36.92	66.92	0	46.21	0	0	19.85	13.41	92.5	13.7	0	0	0	62.5	0	0	31.87	19.96	49.7	54.4
MPN073	85.68090115071047	48.10155857980137	32.539289629360496	74.36288741971168	37.57934261	MPN044	151.68	178.16	158.5	185.5	77.22	73.65	152.6	168.2	58.6	60.4	185.2	163	87.62	79.83	68.48	85.46	156.3	149.4	145.43	193.32	93.31	89.72	135.3	134.9	169.34	160.83	76.9	78.3	92.55	90.03	91.5	92.1	84.93	81.69	96.1	103.4	59.94	59.1	63.2	66.6	83.17	74.24	95.71	102.02	87.6	102.7	105.71	99.45	168.2	157.3	207.66	215.76	194.3	181.6	22.95	25.49	133.33	129.25	196.9	190.8
MPN076	157.08888500972807	233.60637439879076	301.509311624328	332.4203505651681	285.2936847	MPN045	41.01	56.12	46	61.4	38.06	36.43	56.1	54.6	39.96	34.36	42.1	42.3	35.67	24.52	47.48	47.62	67.1	55.8	92.95	50.35	45.76	45.46	51.4	50.2	50.04	53.38	45.1	24.5	29.29	42.43	37.2	25	35.09	36.23	36	40.3	30.62	28.66	39.8	30.9	24.47	38.74	31.03	31.57	18.7	24.5	24.48	38.3	54.7	59.8	42.42	40.74	69	63.3	45.99	42.08	45.45	63.34	50.3	68.5
MPN077	539.7234283524978	210.82946386612988	166.13361772177421	83.48846770530689	62.06819421	MPN046	23.08	20.84	27.8	25.5	18.15	10.53	29.4	27.4	15.68	18.15	31.6	26.3	14.63	12.56	11.73	13.47	32.9	28.4	15.17	22.99	10.92	9.96	30.5	28.3	13.72	12.81	16	11.2	12.98	19.72	15.2	15.1	12.53	12.11	31.4	29.1	16.95	16.6	39.5	33.1	23.42	20.58	22.98	24.24	27.4	26.1	18.91	17.52	36.4	28.4	9.54	8.11	40.4	32.5	13.48	11.74	19.21	15.59	31.2	28.9
MPN078	3.507299783236138	5.283432366778787	3.889505530866252	0.9937349385958589	2.540544073	MPN047	18.11	17.56	22.8	22.2	7.22	3.3	18.9	22.1	4.91	12.83	21.8	22.4	8.54	2.71	3.21	3.36	22	22.2	9.61	8.79	4.69	5.78	20.3	19.2	5.47	7.1	5.5	8.6	5.05	5.27	12.2	9.9	6.26	9.54	22.3	20.9	12.96	9.74	23.8	23.6	11.17	12.84	11.9	10.44	12	16.1	9.1	9.66	20.8	21.1	2.05	1.73	20	20.8	5.28	4.14	9.1	5.53	12.6	16.8
MPN079	5.947155208292791	6.335241178230539	5.118539225596308	5.915688777387425	4.206012769	MPN048	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN080	13.197527191135872	14.260185220825338	7.164371893819408	22.932845936617944	20.87608846	MPN049	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	4.99	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
MPN081	14.497112865667532	22.05194634266108	4.114321470506199	11.842711922690334	15.10966693	MPN050	211.32	218.93	219.1	227	83.91	74.84	180	234.2	65.06	55.95	226.6	187.5	142.19	124	133.53	116.02	201.2	205.4	140.68	109	125.39	120.18	175.7	175.1	164.41	105.88	77.5	97.3	78.31	105.9	78.9	102.2	93.88	91.32	125.1	131.8	82.56	73.63	110.9	110.7	123.98	122.75	146.05	131.25	144.9	167.1	136.84	105.49	153.7	164.6	120	118.43	189.6	203.2	96.58	133.06	179.98	129.81	203	204.9
MPN082	184.45048384547468	234.074218341872	349.70688181674575	317.8727885488968	294.4653666	MPN051	215.65	215.65	223.5	223.6	126.14	126.81	258.3	255.1	58.68	58.28	324.4	319.1	117.1	134	105.89	100.25	254.6	260.8	175.75	209.16	128.06	123.73	253	239.6	360.74	341.85	86.2	81.2	118.29	103.48	91.3	84.8	130.06	129.64	96.8	97.3	96.59	86.41	126	171.4	248.06	241.79	247.41	211.09	188.5	156.2	153.82	143.52	260.3	288.4	263	268.88	289	309.5	73.25	70.37	85.69	65.41	325.8	301.4
MPN083	3.548322981814839	8.415207072266012	3.939603313850121	8.7904073949077	9.969608383	MPN052	306.03	309.89	315.4	319.4	354.32	444.06	296.5	306.7	206.37	208.54	343.5	324.5	209.15	226.75	291.42	329.42	307.2	299.4	546.62	541.53	314.95	324.62	313.3	312.3	316.35	283.23	315.8	315.5	317.34	346.67	262.4	267.2	331.9	288.24	253.2	240.4	170.23	157.76	152.4	149	160.93	166.46	151.15	139.16	185	206.6	216.95	206.21	327.9	316.8	380.92	382.32	348.4	335.9	473.98	464.68	443.29	432.12	352.1	351.7
MPN090	1.882711444969221	0.765848723254819	1.595518174827378	5.424761793885279	4.832140759	MPN053	340.46	365.64	350.4	376.1	486.81	450.53	250.9	258.4	531.2	531.89	230.6	234.3	457.15	451.58	543.89	527.32	295.4	236.4	542.42	388.72	555.5	527.26	474.8	432	181.62	189.21	499.3	660.3	529.25	525.21	500.9	637.1	601.53	584.41	475.2	511.2	580.54	576.29	397.5	432.9	322.51	327.6	589.86	572.78	585.8	676.5	609.48	591.67	603.8	640.4	810.96	772.35	552.1	530	644.43	614.82	786.11	775.4	597.6	578.5
MPN105	79.55156970166774	77.07451481387044	90.60304536698358	47.54039912377849	65.83249662	MPN054	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN106	27.472690072523406	28.464931745374813	22.263421559092524	26.976569275246536	23.44170848	MPN055	45.09	34.39	50.2	39.3	88.23	97.77	36.8	46.2	95.25	102.61	45.8	62.4	48.86	49.11	54.84	58.25	40.6	40	82.79	65.31	38.38	54.56	71.4	67.7	33.71	43.1	85	90.3	69.57	69.71	86.8	87.1	91.01	81.89	60.6	50.9	95.02	103.11	60.5	62.7	74.43	52.55	65.8	92.85	67.8	58	71.52	75.91	78.1	95.9	80.41	87.02	62.9	61.7	33.37	28.04	65.34	64.43	58.2	57.8
MPN109	61.19008599276811	35.00072920454397	12.703061846938386	16.472371166247687	16.91293978	MPN056	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN115	547.6727674745542	356.58160182556344	367.553343371134	231.32088520730733	257.8359273	MPN057	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN117	21.106148809522505	31.638242960638696	6.419961753863732	6.252119622342889	10.23837039	MPN058	22.64	22.08	27.4	26.8	30.57	30.54	26.9	26.6	34.5	37.82	27.2	33.4	20.35	18.83	19.5	17.54	25.5	25.4	22.75	15.94	18.61	17.4	28.1	27.7	21.68	17.61	22.6	25.8	18.6	21.11	28	27.4	22.62	22.58	33.8	27.8	39.71	42.43	33.2	38.5	29.04	31.73	52.22	45.3	59.7	39.3	29.91	25.99	27.9	31.3	20.25	21.17	23.4	24.9	30.35	25.45	21.1	19.5	26.2	22.1
MPN118	10.86981700807244	16.342207663443105	10.420031476245175	36.132771019614985	31.41002296	MPN059	52.75	55.37	58	60.7	25.8	23.84	53.2	54.3	24.19	28.05	51.9	50.9	27.78	29.57	31.59	27.17	51.7	50.4	16.4	24.9	35.9	30.71	39.8	43.1	24.07	25.13	27.8	24	31.76	32.89	24.3	32.1	28.88	30.33	41.4	38.1	24.59	24.32	37.8	43.2	24.75	18.07	41.13	36.94	27.7	28.6	30.14	27.02	37.9	39.9	18.34	15.45	43.8	46.2	12.93	15.26	22.46	24.42	43.4	42.1
MPN119	92.72957977523838	110.1515007877591	24.39068945138349	24.165890466532378	28.66187012	MPN060	50.24	47.8	55.4	52.9	38.73	40.49	55.8	60.5	40.19	42.48	51.2	56.1	36.78	33.58	36.9	38.49	53.3	51.8	29.6	36.79	33.52	36.31	46.6	40.4	21.49	27.97	37.8	28.3	33.79	40.21	37.6	19.5	42.29	34.71	44.2	34.3	33.34	35.62	43.7	36.4	28.45	27.61	35.33	27.46	26.9	32.9	33.18	30.63	40.4	37.5	13.9	15.55	51.4	47.5	40.28	38.7	20.76	22.14	38.7	41
MPN120	158.74743382339994	289.2388516336603	165.42612834704983	101.72165666295228	217.8281939	MPN061	91.49	91.49	97.3	97.4	52.23	49.38	100.4	95.2	55.7	49.08	93.1	105.7	62.78	61.49	58.57	56.57	103.4	102	89.07	76.13	64.67	58.29	150.7	154.8	82.37	81.36	57.1	63.4	61.86	57.17	56.7	64.3	56.9	57.01	72.9	122.9	56.21	52.89	72.2	83.7	76.63	70.42	90.06	93.63	79.6	92.2	72.51	68.19	100.3	101.7	76.02	74.18	111	110.1	56.26	55.25	109.21	110.09	103.5	114.6
MPN121	190.00341844701035	331.735698208358	378.4662688175548	163.30023534496146	272.6805816	MPN062	478.61	489.22	490.8	501.8	364.24	339.06	506.7	483.5	282.95	195.59	477.5	514.1	347.31	354.79	451.99	489.06	501.4	498.8	547.6	717.08	454.42	450.05	487.5	485.9	426.05	251.93	510.6	434.1	447.23	439.08	390.2	334.7	460.59	486.93	433.8	397.6	324.67	337.6	360.2	415.4	352.47	352.96	344.67	312.25	280.5	33.9	384.46	403.11	497.7	550.8	501.33	437.39	511.6	511.3	405.83	428.89	765.38	767.42	519.8	464.4
MPN122	8.161138523789418	5.30675018174789	4.402190491978407	7.4575921158465714	8.924988937	MPN063	250.46	253.76	258.9	262.4	207.83	182.8	245.9	238.4	191.21	202.7	265.2	275.2	220.22	213.3	220.39	246.24	275.3	284.8	165.3	265.27	226.25	241.93	273.6	272.7	254.94	263.02	289.4	323.4	195.42	246.94	263.9	273	205.38	253.33	200.1	200	183.02	158.29	175.7	175.5	198.89	200.93	236.77	228.17	288.8	273.7	223.8	208.15	252.8	252.7	284.14	296.16	269.8	288.9	221.71	217.38	248.58	258.5	286.7	286.4
MPN123	12.873367799963402	68.26130323153389	4.262274722526925	11.142494836090963	13.52244518	MPN064	201.17	188	208.8	195.5	176.07	172.03	223.5	220.2	134.07	144.72	201.1	190.5	142.75	156.35	160.83	166.69	219	244.2	191.31	247.27	165.72	170.09	210.3	209.6	172.32	173.5	186.8	169.9	155.51	187.24	174	137.1	153.09	166.66	162.1	153.9	136.94	139.79	146.1	139	150.73	145.09	147.94	135.08	136.3	133.7	151.63	146.7	205	225.1	129.22	146.85	284.8	260.7	202.16	191.86	303.1	220.92	254.3	271
MPN124	108.3749858705252	106.20748622831562	65.02499161459943	65.02499161459943	71.52749075	MPN065	21.16	16.27	25.8	20.9	8.17	6.63	21.4	24.1	26.98	36.88	18.5	18.5	18.99	43.42	7.51	12.9	30.5	32.9	5.8	21.56	20.01	26.02	25.4	32.8	0	0	35.6	10.4	13.49	8.07	35.7	21.3	12.91	14.69	31.5	30.7	81.31	58.19	31.2	43.4	30.56	48.07	63.03	56.52	69.7	60	55.18	42.25	25	39.5	23.25	19.2	31.2	27.8	34.43	20.43	7.41	7.58	21.4	22
MPN125	10.281280162070956	16.00724067289583	11.375574832227688	7.532819129542198	6.107691191	MPN066	109.76	98.09	115.9	104.1	75.03	56.95	115.7	112.9	90.87	86.33	112.2	99.4	60.37	58.23	50.9	52.96	99.4	86.8	70.73	80.34	68.35	50.54	122.1	113.4	59.6	60.88	76.1	54.6	48.68	64.5	62.4	53.1	55.35	57.1	87.8	86.1	72.41	87.71	110.1	115.7	110.66	89.65	107.73	101.47	77.7	33.8	73.67	79.84	128.2	115	46.61	43.97	111.7	105.1	65.58	65.12	97.64	110.51	129.9	108
MPN126					4.619280715	MPN067	246.33	246.33	254.7	254.8	227.08	179.97	255	246	242.56	276.72	262	226.7	264.34	209.32	174.07	201.37	215.4	248.3	179.91	148.28	177.53	203.87	205.2	199.3	249.17	239.52	227.9	214.6	213.74	226.46	289.6	287.2	235.57	210.55	260.7	279	313.84	307.31	313.4	304.9	346.04	347.95	397.61	408.47	384.4	441	309.91	186.25	232.7	232.6	222.58	230.45	217.9	214.2	197.98	193.98	191.16	193.01	207.4	217.7
MPN134	87.8244929269997	80.57684063442056	199.52360496658767	133.86840162316167	103.598795	MPN068	15.61	14.49	20.2	19.1	24.52	41.2	17.8	20.1	21.3	18.3	16.9	16.9	9.63	19.3	10.8	13.99	24.5	0	0.02	0	0	17.74	21.1	19.4	5.82	6.28	0	8.9	18.99	11.64	4	14.5	20.87	15.58	22.6	23.3	23.48	19.98	0	15	6.38	12.28	14.52	10.93	3	5.2	10.97	10.44	23.1	18.4	0	0	21.5	20.9	11.39	2.15	7.14	8.12	14.1	0
MPN140	130.5307296440782	183.07487894933803	107.30068454778191	208.51730953013464	216.2606578	MPN069	0	15.22	0	19.8	0	0	13.6	13.6	0	13.41	20.5	21.3	7.69	0	0	0	19.6	19.6	11.14	11.06	0	0	21.6	21.6	5.87	0	10.6	8.9	0	0	7.7	5.5	0	0	33.5	33.2	17.68	0	22.3	22	18	13.74	19.79	17.74	19.4	0	0	0	17.9	20.4	0	0	16.8	17.5	0	0	0	0	0	0
MPN141	771.5845474031846	963.3656776334873	588.7234695904614	566.4233384925003	606.5635745	MPN070	0	0	0	0	12.85	31.18	13.6	13.6	9.61	0	0	0	7.66	5.67	9.27	9.68	0	0		0	8.55	8.02	0	0	0	0	4.6	0	5.78	6.41	0	0	4.69	0	0	0	7.89	0	0	0	3.66	4.79	0	0	0	0	3.84	6.74	0	16.6	0	0	0	0	0	1.56	0	0	11.8	0
MPN142	906.6534407285876	578.382366690049	294.7740246377717	504.68886043259243	216.3909318	MPN071	21.59	0	26.3	0	6.12	15.52	13.6	13.6	10.61	22.99	28.6	0	10.08	7.8	8.97	7	21.7	26.6	12.31	7.34	7.49	15.18	26.5	26	14.03	11.38	18.7	18.4	5.85	6.48	11.4	22.4	8.37	16.16	28.6	27.8	11.86	15.37	26.1	30.7	14.78	10.73	30.87	12.37	16.1	0	10.73	11.15	21.1	20.3	7.47	12.04	24.6	24.2	7.36	6.66	13	11.95	20.6	21.1
MPN153	141.03861343699845	200.02316399392623	244.85142208641943	102.50204068441808	188.4884073	MPN072	17.42	16.81	22.1	21.4	13.07	13.54	22	21.4	13.05	11.34	21.5	21.9	16.86	9.14	15.89	14.71	19.7	21.2	8.89	8.07	10.05	8.61	21.9	21.1	13.36	9.46	12.6	9.8	13.56	14.41	14.6	8.7	12.3	12.36	20.1	19.7	10.27	16.83	20.7	22.2	20.56	19.39	23.31	14.82	9.4	14.6	9.19	9.16	19.8	18.8	7.05	12.18	17.5	18.7	8.54	8.34	7.16	11.34	16.9	14.2
MPN154	275.6122067752049	158.13815166889876	208.59175228069887	115.96797786314387	118.9801331	MPN073	85.59	68.94	91.3	74.4	147.46	136.76	165.7	146.4	112.08	113.25	158.3	151.7	161.47	153.15	164.71	108.54	136.2	141.6	138.53	168.98	171.1	157.83	121.1	118.7	160.04	156.34	136	129.1	131.39	134.56	148.9	153.5	146.68	139.34	98	100.4	150.1	146.04	100.4	108.1	149.63	157.34	162.67	172.85	89.7	150.2	162.64	156.98	113.7	125.8	139.62	108.76	133.3	127.1	162.41	150.78	176.36	176.23	133	144.2
MPN155	109.0243471936625	88.55029144584162	197.06278714937795	76.77770935903109	121.3087808	MPN074	0	0	0	0	3.57	0	13.6	13.6	0	11.49	0	0	0	2.47	4.17	5.03	0	0		0	0	3.48	0	0	0	0	0	0	3.22	0	0	0	4.75	5.91	0	0	7.47	3.91	0	14	2.02	0	2.72	1.28	0	0	4.33	2.94	0	0	0	0	0	0	0	0	0	0	0	0
MPN157	82.30216549705524	105.94214927275212	84.9288304185531	63.25884531388418	80.55105564	MPN075	14.15	14.72	18.7	19.3	3.9	6.42	19.4	13.6	1.35	3.84	18.2	17.9	1.87	3.06	1.28	0.66	18.9	19.1	6.14	2.51	2.05	3.03	16	15.9	2.04	2.68	2.2	1.9	1.82	1.22	2.8	4	0	4.09	17	16.3	2.33	1.41	15.6	16.4	3.26	2.37	3.32	2.69	0.1	3	2.56	2.14	16.4	16.1	0.57	0	16.2	15.9	1.43	0.81	1.97	1.99	10.9	11
MPN159	10.369673857146323	9.89070508086173	7.495861237514524	12.812414561297576	11.56709577	MPN076	253.76	256.97	262.3	265.6	463.74	481.55	261.5	276.6	218.37	213.24	258.6	271.1	249.09	273.51	279.22	273.55	300.9	309.6	260.49	197.23	258.2	274.99	299	287.8	161.15	170.73	247.9	220.3	282.13	293.14	211.7	215.3	206.41	210.68	229.4	210.4	213.83	220.83	244	278.6	218.38	238.14	196.29	185.23	242.7	185	219.09	225.54	256.9	260.2	62.09	69.39	313.6	302.4	229.3	225.83	138.31	276.71	291.3	316
MPN161	53.226205177577256	95.71275491195523	49.09556844053269	109.99295628681365	154.6038333	MPN077	64.01	82.27	69.4	88	166.74	164.47	94.6	91	111.55	89.9	74.8	87.9	111.16	106.06	107.18	85.24	118.8	116.8	141.18	71.92	103.74	98.59	107.3	104.7	58.35	59.7	74.5	62.5	105.03	95.94	64.3	69.2	71.41	57.61	74.4	68.6	101.33	95.81	123.8	117.2	110.01	105.25	103.74	103.12	112.3	87.2	122.46	116.18	123.7	129.3	30.53	29.33	146.3	144.1	74.92	71.74	155.27	152.66	149.1	155.9
MPN162	153.9355678911658	147.11563755339026	162.7040495341197	99.37612615100453	141.2699831	MPN078	15.12	15.71	19.7	20.3	36.23	43.69	19.3	20.2	27.21	13.92	17.5	20.1	42.66	44.73	11.34	10.98	20.4	20.4	13.55	15.41	11.17	11.95	20.9	20.7	6.64	5.09	15.5	20.9	12.23	10.62	7.6	20.3	13.26	5.75	21.6	20.7	32	21.83	21	20.9	28.37	30.21	14.01	9.84	21.4	5.3	36.71	13.99	21.7	23.3	6.12	2.6	23.2	22.5	40.05	3.01	21.29	20.98	19.1	19.5
MPN163	11.829989538372843	17.550760610985918	27.509139874992076	47.67309222904063	54.3826385	MPN079	23.87	21.38	28.6	26.1	6.54	6.12	36.3	32.2	11.66	10.05	25.5	30.5	7.45	6.44	8.19	6.25	23.6	20.7	9.17	0	6.76	6.07	23.2	20.5	6.11	4.56	4.7	7.6	7.14	6.35	6	0	8.72	5.47	24.6	26.5	12.3	10.47	35.7	21.8	9.03	8.56	6.96	6.73	16.7	9	10.04	9.33	26.3	23.5	9.87	9.02	26.3	23.8	6.33	5.24	10.53	10.28	22.1	24.5
MPN164	13.75673407679941	46.86836843449229	30.507836082426575	14.537873523772895	23.69456403	MPN080	15.22	15.56	19.8	20.2	34.76	13.29	21.9	19.1	11	11.77	28.9	31.6	9.11	6	6.21	6.12	19.5	18.8	6.1	3.46	33.82	4.84	19.6	19.5	5.74	6.08	11.7	10.7	6.81	6.62	11.6	11.5	7.91	6.93	21.3	20.9	29.69	12.3	21.3	22.8	13.71	15.51	17.28	14.38	18.6	19.7	11.99	8.03	19.3	19.9	8.6	3.07	18.2	18.6	39.79	6.58	6.21	6.32	14.2	94.4
MPN165	388.78433179739295	311.3793066939671	106.08006870053937	188.23494797426048	230.4558709	MPN081	19.66	13.76	24.3	18.3	5.8	11.71	27.1	25.5	14.13	17.63	22.2	25	12.75	12	10.77	11.23	21.4	21.5	4.44	4.13	8.12	11.32	19.7	18.5	9.32	6.47	13.9	11.6	9.8	11.73	12.2	13.7	12.88	11.8	21.2	21.7	21.87	23.51	24.2	23.1	13.01	11.57	22.76	26.73	24.1	22.3	15.84	17.82	20.1	20.9	10.85	9.85	19	20.4	8.27	11.58	14.77	14.9	16.7	17.3
MPN166	170.63068288060154	176.81295397347893	59.59709360811722	57.49512147310746	84.94440524	MPN082	449.05	449.05	460.7	460.9	265.98	309	429.8	412.5	191.56	203.27	460.2	460.4	406.49	339.82	352.93	353.48	399.9	354	195.71	247.62	395.75	322.32	317.1	316.1	482.44	464.78	265.8	284.5	333.66	309.31	397.7	356.8	274.86	276.65	305.6	293.6	262.45	226.27	263.8	316.8	314.05	317.88	376.18	379.87	418.9	448.3	316.46	303.56	305	312.9	288.28	281.35	322.9	328.4	379.64	383.04	262.38	280.08	345.1	339
MPN167	128.89963306278312	360.2579488877323	607.3155792314374	363.97620797074944	190.8706107	MPN083	19.56	17.97	24.2	22.6	13.6	12.67	22.4	22.6	17.49	14.51	19.6	21.7	14.24	12.85	11.11	10.32	18.1	18.6	8.97	13.06	11.97	11.86	21.3	16.8	9	10.36	8.4	9.6	9.43	6.21	13.9	14.1	10.43	8.3	25.3	24.6	19.99	14.01	22.8	22.4	18.18	17.66	22.55	18.73	21.2	25.2	17.56	13.42	22	24.7	15.07	11.92	22.3	22.2	14.08	11.82	8.13	6.07	0	0
MPN168	319.98437793752686	337.4380712262004	164.3556120540437	102.97679074947938	123.048538	MPN084	22.94	26.38	27.7	31.2	3.03	4.65	22.7	28.9	11.18	12.51	30.2	29.3	10.01	10.49	11.98	13.11	17.2	20.2	9.25	7.08	6.5	9.55	16.6	14.3	5.44	6.08	5.8	7	3.53	2.82	6.4	7.6	3.42	3.47	21.8	24.2	7.04	9.94	22.5	19.7	11.59	10.18	39.05	13.59	16.4	7.8	14.83	13.73	29.3	26.8	18.61	15.05	36.5	34.2	14.34	14.78	15.94	15.38	22.9	22.9
MPN169	22.421715379465052	16.33582120189125	0.5562720808327407	9.662691617331403	8.018432495	MPN085	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.37	0	0	0	0
MPN170	2.7430150147251156	22.16356133048259	1.7994178481031973	6.144353628256558	9.852909933	MPN086	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN171	156.98977029135696	129.57595698067834	174.71736931874807	144.5621750824687	114.5897392	MPN087	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN172	35.96572061609393	24.703727285680152	38.79938344402736	27.46473211292811	24.26777917	MPN088	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN173	78.6743610086042	35.86126583477558	15.514448362895171	53.83428796557454	22.04238564	MPN089	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN174	1.1572158368120795	146.96641129003848	1.1572158368120795	36.915185189444934	74.40897832	MPN090	0	0	0	0	8.69	0	13.6	13.6	0	2.06	0	0	17.83	0	6.94	2.4	0	0		0	0	4.86	17.3	15.2	0	0	3.1	0.3	0	4.31	2.4	0	0	4.02	14.9	0	0	0	14.7	0	0	0	0	0	0	0	11.12	0	15.7	14.1	0	0	20.2	0	0	0	0	0	0	0
MPN175	28.304518924164967	12.657200269900786	14.050653498464762	6.009267098012115	8.825203851	MPN091	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN177	124.56946346963649	96.70524151995299	107.63238750403046	11.801317587771301	43.43540506	MPN092	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0
MPN178	49.507987143699914	126.13774115728216	28.972935093613536	14.249690198815124	22.90282536	MPN093	0	0	0	0	41.88	53.47	0	0	31.67	27.44	0	0	48.44	40.93	36.02	31.58	0	0		0	37.04	40.24	0	0	58.85	57.9	31.4	25.2	40.97	36.82	50	43.8	38.54	34.21	0	0	46.76	44.47	0	0	33.7	51.59	33.21	50.64	44.7	93.2	44.12	45.48	0	0	36.93	74.92	0	0	31.13	31.76	0	0	0	0
MPN179	117.78838550955561	67.19869762260318	179.64847299807522	20.59178253384315	35.67547507	MPN094	0	0	0	0	6.36	13.56	23.7	13.6	12.65	9.89	20.1	21	13.91	7.86	17.41	4.56	0	0		0	10.67	8.76	26.6	25.1	8.37	8.03	13.3	36.2	15.98	3.16	10.1	32.4	16.85	5.02	17.1	17	10.22	10.22	15.8	16.1	6.77	6.31	0	0	3.4	0	8.34	4.52	24.4	21	11.14	9.05	18	19.2	12.04	5.57	11.95	12.77	15.6	15.4
MPN180	266.1133278135447	329.842733526384	48.830503901322565	145.54418246256938	113.6794799	MPN095	0	0	0	0	1.81	0	0	0	0	0	0	0	0	0	0	0	0	0	0.13	0	0	0	0	0	0	0	1.1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2.55	2.6	0	0
MPN181	35.539351497287775	62.74231181790048	7.305311141719943	8.40220469759868	11.93420198	MPN096	0	0	0	0	3.83	3.05	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1.52	0	0	0	0	0	0	0	0	0	0	0	0
MPN182	110.95643217003452	187.32213001780238	89.40374382113494	120.80148733507538	156.4565518	MPN097	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0			0	0			0	0			0	0			0	0	0	0

TIME h	Glucose	Lactate	Acetate	Protein mg/ml	molecules glucoses/cell/s	TIME h	pH	Glucose	Lactate	Acetate	protein	molecules glucoses/cell/s					WODKE paper MSB modeling metabolism
0	52.21	4.7315E-5	5.299E-6	0.023376		0	7.9064	60.317	0.0037048	0.0021653	0.0079953						Time Hours	Protein in concentration mg	Glucose mM	lactate mM	acetate mM
16.839	59.103	0.52636	1.3715	0.0074101	3971	14.129	7.8784	60.836	0.025809	0.57419	0.0044266	12982					0	0.005	60	4	1.5
						20.71	7.8627	59.603	0.014315	1.0263	0.0047978	24921					15	0.009	58	4	3.3
30.387	52.495	0.98531	1.8481	0.018839	5082	31.161	7.8291	59.271	0.78443	1.75	0.011811	16903					25	0.013	57	4.5	5
38.129	55.492	1.3769	2.3426	0.023362	18455	38.903	7.805	59.887	1.9383	2.4438	0.014066	16594					31	0.02	55	5	5.7
48.968	47.746	5.6969	3.6089	0.037265	10222	50.71	7.7583	54.47	4.4025	3.274	0.018969	22749					37	0.021	52	7	6.2
57.484	46.477	9.4358	3.7477	0.043614	21848	59.806	7.6959	52.19	8.4369	3.9317	0.024116	35913					42	0.029	50	11	7.8
68.323	37.659	20.834	4.6963	0.055532	29026	69.677	7.5734	46.825	17.6	4.9883	0.031837	48669					48	0.031	48	15	8.5
76.065	31.028	34.897	5.551	0.070175	16729	78.194	7.3817	39.065	32.331	6.0332	0.038412	32017					52	0.037	43	20	9.2
110.9	15.055	82.097	7.238	0.06159	-1320	93.097	6.9224	30.213	52.866	7.4079	0.042395	25142					60	0.042	33	25	10.2
129.48	13.129	80.202	7.3275	0.065479	3321	110.52	6.0605	19.325	73.732	8.7422	0.047348	10580					72	0.048	21	53	12.1
144.19	13.742	83.697	7.6564	0.075757	2157	134.13	5.0941	10.879	81.24	9.6941	0.046939						84	0.057	15	77	14.1
																	96	0.046	12	80	15.2
																	108	0.052	9	90	16.1
			mM			molecules/ml.sec					molecules/cell.sec						124	0.044	11	98	16.2
time1	time2	dt	Dlac mM	Dace mM	D glc used	lac	ace	glc	ATP	cells/ml at t1	lac	ace	glc	ATP			136	0.048	10.5	90	16
0	24	24	0.49912	1.3684	0.93376	3.4793978703703706E12	9.539205092592592E12	6.509301481481482E12	1.6273253703703707E13	728300000	4777.4239604151735	13097.90620979348	8937.665085104329	22344.162712760823			148	0.048	10.5	90	16.1
24	48	24	4.72968	0.9328999999999998	2.83129	3.2970905833333332E13	6.50330636574074E12	1.9737106099537035E13	4.9342765248842586E13	2102600000	15681.016757030977	3092.983147408323	9386.99995221965	23467.499880549123			155	0.048	10.5	90	16.2
48	72	24	21.2762	1.8657999999999997	11.571	1.4831776921296294E14	1.300661273148148E13	8.066219097222222E13	2.0165547743055556E14	3.4384E9	43135.693698511786	3782.751492403874	23459.222595457835	58648.05648864459			165	0.042	10.5	90	16
72	96	24	37.405	1.6493000000000002	19.52715	2.6075267939814812E14	1.1497377199074076E13	1.3612502829861111E14	3.4031257074652775E14	5.1852E9	50287.873061434104	2217.3449816929096	26252.60902156351	65631.52255390877			180	0.051	10.5	90	16.2
96	120	24	8.881	-0.16129999999999978	4.35985	6.191002662037037E13	-1.1244327546296282E12	3.039279693287037E13	7.598199233217592E13	4.8651E9	12725.334858557968	-231.12222865503858	6247.106314951465	15617.765787378661
120	144	24	-7.923000000000002	0.03230000000000022	-3.945350000000001	-5.523174652777779E13	2.2516539351852E11	-2.7503290567129637E13	-6.875822641782409E13	5.0571E9	-10921.6243554167	44.52460768395325	0	-13596.374684665934


t0 (h)	t (h)	dt	cells/ml	D lac (mM)	Total lac/ml	lac/cell.sec	D ace (mM)	Total ace/ml	ace/cell.sec	gluc /cell.sec	Produced ATP/cell.sec	D gluc (mM)	Total gluc/ml	gluc/cell.sec	Produced ATP/cell.sec (max)	Produced ATP/cell.sec (min)	ATPs for protein/cell.sec (assuming cell# of t0)	ATPs for protein prod/cell.sec assuming average cell number		Dmole ace+lac	dpH	b if pH change only by ace+lac	pH change should be (HCl)	ratio	t1/2	k	0.014926600860541634	t0 (h)	dt	1.4926600860541635E9	Dcells/ml
18.25	26.75	8.5	1.4926600860541635E9	0	0	0	0.45211269575024504	2.72307476650372544E17	5961.797483954494	2980.898741977247	10433.145596920365	1.2326388888888857	7.4241840277777587E17	16254.229300523331	56889.80255183166	39010.15032125599	381.9353581195087	402.1644842165756		4.5211269575024506E-7	0.04369461514422124	1.0347103281673794E-5	0.0054255693717778115	8.05346170145894	20	0.03465735902799726	0.01529781489918164	18.25	8.5	1.529781489918164E9	3.712140386400056E7	2.4869294898968413
26.75	40.25	13.5	1.529781489918164E9	0.7701149425287368	4.6384022988505818E17	6238.824116290289	0.7237473871076312	4.3591305125492627E17	5863.193146159066	6051.008631224677	21178.530209286368	0.33203125	1.99982421875E17	2689.8381728058894	9414.433604820613	6455.6116147341345	2134.254247000957	2114.627172171829		1.493862329636368E-6	0.033569603109482316	4.450044657258402E-5	0.017927065038237947	1.872565477833614			0.02231080739053404	26.75	13.5	2.2310807390534043E9	7.012992491352403E8
40.25	50.25	10	2.2310807390534043E9	1.1538461538461529	6.9496153846153779E17	8652.527379030491	0.6937696846830539	4.1785748108460333E17	5202.479699266616	6927.5035391485535	24246.26238701994	-0.61631944444445	-3.7120920138889222E17	-4621.691418313208	-16175.919964096227	-11092.059403951698	3869.629989390979	3781.097550306212		1.8476158385292067E-6	0.024081764061146593	7.672261192485236E-5	0.022172276953428615	1.0861204788181533			0.024565510841137266	40.25	10	2.4565510841137266E9	2.2547034506032228E8
50.25	65.5	15.25	2.4565510841137266E9	2.4641909814323615	1.48418222811671117E18	11004.975569194396	0.8301988202071469	5.0002874941076448E17	3707.633784392389	7356.304676793392	25747.066368776872	5.4166666666666785	3.2624583333333407E18	24190.610542080125	84667.13689728043	58057.4653009923	2381.429450550757	2349.445435853442		3.2943898016395085E-6	0.04676281607554689	7.044891813866197E-5	0.039534258990033704	1.182842862625437			0.029469332658398722	50.25	15.25	2.9469332658398724E9	4.9038218172614574E8
65.5	77.25	11.75	2.9469332658398724E9	4.0344827586206895	2.4299689655172408E18	19493.510593138897	0.6576740838044817	3.961171006754393E17	3177.700212519589	11335.605402829244	39674.618909902354	2.2808159722222214	1.37373546006944384E18	11020.27520640952	38570.96322243332	26448.660495382846	2858.287120339971	2791.690866600189		4.692156842425171E-6	0.062306606109505225	7.530753374976969E-5	0.056308134434479434	1.1065293981992186			0.03461570910318063	65.5	11.75	3.4615709103180633E9	5.146376444781909E8
77.25	90	12.75	3.4615709103180633E9	9.163351016799295	5.5190863174182144E18	34736.11694952898	1.0565610630049687	6.3636672824789261E17	4005.175462729206	19370.64620612909	67797.26172145182	5.364583333333329	3.2310885416666639E18	20335.87862240922	71175.57517843226	48806.108693782124	2711.804760000786	2643.290350617124		1.0219912079804264E-5	0.12252135998098801	8.341330916821457E-5	0.12264385071167963	0.9990012484932523			0.04233738294102758	77.25	12.75	4.2337382941027584E9	7.721673837846951E8
90	101	11	4.2337382941027584E9	14.730327144120249	8.8720760389036268E18	52918.3215048531	1.0449370559423796	6.293655887940951E17	3753.909505042157	28336.11550494763	99176.4042673167	7.760416666666671	4.6740989583333356E18	27879.097331671237	97576.84066084932	66909.83359601097	2999.89701503653	2929.9461102017085		1.5775264200062632E-5	0.19176946261276306	8.226160716692086E-5	0.18931074283046478	1.0129877456796001			0.04891166793216907	90	11	4.891166793216907E9	6.574284991141481E8
101	120.25	19.25	4.891166793216907E9	20.53492484526968	1.2368185234305927E19	36488.85817012686	1.3746917826127145	8.2797686066763789E17	2442.7132731848797	19465.78572165587	68130.25002579554	8.851996527777779	5.3315575086805555E18	15729.263596450088	55052.4225875753	37750.23263148021	2437.868569263136	2421.871629373696		2.190961662788239E-5	0.45927144532222464	4.770515748591906E-5	0.26292591657125153	1.7467713008723675			0.05289483675018983	101	19.25	5.289483675018983E9	3.9831688180207634E8
120.25	142.75	22.5	5.289483675018983E9	20.866489832007062	1.256788682581785E19	29333.505148681335	1.334313652816352	8.0365711309128883E17	1875.7393658423262	15604.622257261832	54616.17790041641	10.88758680555556	6.557593532986113E18	15305.453202176652	53569.08620761828	36733.08768522396	2224.9798048941143	2216.213893288781		2.2200803484823415E-5	0.8618702078475984	2.5758870979270592E-5	0.35521285575717465	2.426348579108796			0.05784822407829241	120.25	22.5	5.784822407829241E9	4.953387328102579E8
142.75	173.25	30.5	5.784822407829241E9	13.187444739168882	7.9427979664014172E18	12504.92654629627	0.9519449994416487	5.7335647316370496E17	902.6769423173403	6703.801744306806	23463.306105073818	8.446180555555554	5.0871345486111099E18	8009.047206110567	28031.665221386982	19221.71329466536	2193.395840676057	2193.979316583323		1.4139389738610532E-5	0.9664560821712032	1.4630142020365293E-5	0.6787993153437605	1.423772918335615			0.05743904496751878	142.75	30.5	5.743904496751878E9