Selected Cell
Cell:
Value:
Casaminoacids_Metabolome
Glc_Metabolome
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| Normalized peak area | Analysis is based on three independent biological replicates for each condition | |||||||||||||
| Cultivation 1 | Cultivation 2 | Cultivation 3 | NA | not available (compound found on only one condition) | ||||||||||
| Compound | CasAA:1 | CasAA:2 | CasAA:3 | CasAA:4 | CasAA:5 | CasAA:6 | CasAA:7 | CasAA:8 | p-value adjusted | |||||
| 1-O-methyl-alpha-glucopyranoside | 40163.3455 | 17445.1214 | 56276.1051 | 8199.9376 | 9782.0925 | 12627.4705 | 8860.3776 | 11242.2943 | 0.00710323974999952 | |||||
| 2-amino-2-methyl-3-hydroxy-propanoate | 21101.5782 | 19756.8748 | 21926.3919 | 23136.8444 | 25068.0037 | 20642.521 | 21284.5627 | 21522.191 | NA | |||||
| 2-hydroxyglutarate | 43650.7219 | 35327.2736 | 42961.648 | 33660.4185 | 34466.6312 | 36560.1443 | 35078.3383 | 35135.7501 | 0.00710323974999952 | |||||
| 2-hydroxyphenylacetate | 27231.9197 | 31773.6437 | 35083.7446 | 34557.8158 | 30790.9231 | 35133.7798 | 34063.394 | 36507.8259 | NA | |||||
| 3,4-dihydroxybenzoate | 5751.6606 | 5262.8578 | 5807.5972 | 5684.8573 | 5689.1807 | 5612.7746 | 5718.8937 | 5769.4063 | NA | |||||
| 4-hydroxybenzoate | 286878.4176 | 326186.7881 | 352008.5724 | 327947.2575 | 301455.1309 | 337929.8908 | 329085.9444 | 357019.7407 | NA | |||||
| 4-hydroxyphenylacetate | 700780.8367 | 707189.428 | 817455.2801 | 724525.9151 | 697224.1558 | 738142.5544 | 758592.7242 | 770200.9457 | 0.00710323974999952 | |||||
| 4-methylthio-2-oxobutanoate | 1749.7964 | 3513.8968 | 1942.5159 | 2739.1582 | 1486.8946 | 2334.599 | 1525.8605 | 1554.4995 | NA | |||||
| alanine | 5247.1126 | 2967.5507 | 16159.6084 | 24709.7849 | 36093.0392 | 23718.9533 | 30859.5251 | 20300.3808 | NA | |||||
| aspartate | 1157481.8601 | 1110972.1164 | 853768.8155 | 1038892.9809 | 913918.5727 | 1022042.2124 | 869286.0238 | 993147.6086 | 0.00710323974999952 | |||||
| butyro-1,4-lactam | 81160.8445 | 81828.1482 | 87822.058 | 71394.5326 | 73422.6879 | 76717.3484 | 76195.4975 | 76722.4013 | NA | |||||
| cyanamide | 1446648.6515 | 1891428.1629 | 1379962.3111 | 1208772.658 | 1181006.7649 | 1323768.9502 | 1497653.5665 | 1318634.8366 | 0.00710323974999952 | |||||
| fumarate | 9567.2656 | 8518.0003 | 10744.5254 | 8475.2742 | 9371.9493 | 8588.1613 | 7887.4271 | 7828.8974 | 0.00710323974999952 | |||||
| Glucopyranose_[-H20]_(4TMS)_1763.61 | 97969.6701 | 101096.2828 | 104879.4576 | 87855.2591 | 94608.1436 | 100358.492 | 103992.6352 | 103980.8092 | 1 | |||||
| glucose | 16576.194 | 14429.0999 | 14825.2829 | 14704.5616 | 13209.0779 | 13060.6419 | 11627.9371 | 12735.7824 | 0.00710323974999952 | |||||
| glutamate | 832751.9117 | 734752.4187 | 780777.7428 | 706937.4738 | 663473.1924 | 795270.8992 | 677387.764 | 821135.0777 | 0.00710323974999952 | |||||
| glycerate | 44657.3338 | 42212.2689 | 36152.2379 | 29603.19 | 30094.5479 | 33094.5296 | 29452.4188 | 30671.5721 | 0.00710323974999952 | |||||
| glycerol-3-phosphate | 307900.9752 | 225980.7286 | 385741.8288 | 315459.3148 | 296727.2244 | 288023.2112 | 281860.1665 | 283652.8306 | 0.00710323974999952 | |||||
| glycine | 1033067.4738 | 1104269.7293 | 902517.9322 | 868488.2373 | 857060.1374 | 989858.1105 | 896313.5769 | 979964.0236 | 0.00710323974999952 | |||||
| glycolate | 3166.1953 | 3433.3427 | 3165.1953 | 3074.2872 | 2612.3621 | 3382.7517 | 2323.2383 | 2692.6095 | 0.239241817090161 | |||||
| homoserine | 51609.7692 | 46298.9953 | 52428.8401 | 63336.4081 | 54992.5082 | 59081.6175 | 55191.8195 | 55547.5643 | NA | |||||
| isoleucine | 1250372.5767 | 1336848.9571 | 1137347.8692 | 1029880.9446 | 1026584.8711 | 1051312.5727 | 1040749.9356 | 1139841.613 | 0.00710323974999952 | |||||
| KDG | 39460.5694 | 37328.153 | 31646.395 | 37345.0228 | 36731.9273 | 32327.8053 | 28877.7698 | 31700.0851 | NA | |||||
| leucine | 1284649.8469 | 1298876.0182 | 1126556.5811 | 1080812.8348 | 1059810.8406 | 1097376.9771 | 1047160.0692 | 1193229.946 | 0.00710323974999952 | |||||
| lysine | 886383.0653 | 1054845.9988 | 711034.3495 | 654004.795 | 461941.4216 | 851550.6336 | 571569.1956 | 808912.8072 | NA | |||||
| malate | 6511.1534 | 6156.6194 | 6750.0892 | 6090.3323 | 5958.8636 | 6363.907 | 5586.8382 | 6043.0211 | 0.00710323974999952 | |||||
| methionine | 218049.1155 | 205572.7455 | 200417.1416 | 191137.1143 | 153344.286 | 200303.8921 | 183388.685 | 191829.7323 | NA | |||||
| myo-inositol | 104272.0845 | 89406.0548 | 109301.5632 | 75326.9587 | 77423.2781 | 86291.9142 | 85350.4306 | 87229.8708 | 0.00710323974999952 | |||||
| NA_2615.1 | 92160.0236 | 51895.2277 | 137171.8187 | 132977.339 | 138210.7827 | 130189.8205 | 62801.6799 | 121765.0045 | 0.757007456892091 | |||||
| NA168015_1687.88 | 2456.3358 | 2105.011 | 2419.367 | 1953.7973 | 2317.7955 | 2221.8591 | 2333.7574 | 2216.8173 | 0.00710323974999952 | |||||
| NA192001 | 2213.6737 | 1925.4388 | 1994.8302 | 2003.6217 | 1872.1681 | 1765.3087 | 1600.4372 | 1709.9861 | 0.0314352099570089 | |||||
| NA226 | 10477.8577 | 10326.5833 | 11384.4304 | 10729.5401 | 11050.5932 | 11463.7236 | 11774.7381 | 11735.9489 | 0.103613619183413 | |||||
| NA283 | 15265.6063 | 17240.4399 | 17839.8526 | 12109.7212 | 13843.9029 | 17812.7124 | 17613.3244 | 16025.2778 | 0.00710323974999952 | |||||
| NA69 | 5528.5396 | 4414.4696 | 5825.3703 | 4372.5291 | 3239.8122 | 5916.3954 | 3289.9601 | 3471.9357 | NA | |||||
| N-acetyl-putrescine | 6893.148 | 10669.655 | 7564.2294 | 4427.8764 | 6282.6379 | 5811.2919 | 5432.3692 | 6015.2911 | NA | |||||
| Nicotinamide | 15524.9855 | 15110.7209 | 13549.519 | 13475.8254 | 8364.6541 | 13595.0535 | 9428.1071 | 10329.3556 | 1 | |||||
| Norspermidine | 96207.8704 | 84926.8071 | 76848.2319 | 64064.7269 | 44563.6162 | 69287.9987 | 47580.6218 | 79626.1139 | NA | |||||
| palatinose | 868561.9416 | 469645.802 | 1454174.3206 | 1278929.9738 | 1654745.3965 | 1287607.6918 | 1734897.0491 | 1292621.7159 | 0.497066381143027 | |||||
| phenylacetate | 9365.5564 | 14651.8575 | 11587.2176 | 19667.9326 | 18186.5721 | 15775.2667 | 12076.8771 | 15273.0696 | NA | |||||
| phenylalanine | 1013927.5745 | 982347.989 | 927635.4906 | 880019.7793 | 830532.7105 | 915314.8255 | 898348.1956 | 966421.8238 | 0.00710323974999952 | |||||
| pipecolate | 31196.1152 | 17532.4583 | 33838.0964 | 25843.085 | 23615.6102 | 26391.6994 | 26731.492 | 29652.2617 | NA | |||||
| proline | 8158586.4125 | 7972058.2246 | 7763380.177 | 6845331.5966 | 6517082.4592 | 7281120.1807 | 7089839.3945 | 7542070.5675 | NA | |||||
| propane-1,3-diamine | 2848.5727 | 3095.5758 | 2995.801 | 1910.4817 | 2713.9739 | 3064.421 | 2304.9535 | 2746.5712 | 0.0583537092643266 | |||||
| putrescine | 137914.8398 | 138148.4677 | 144615.2117 | 105998.5226 | 130439.7199 | 134759.5581 | 119776.9266 | 133733.3092 | 0.0583537092643266 | |||||
| pyroglutamate | 9223255.7897 | 8844735.116 | 8352979.1769 | 7888657.1853 | 7806012.5415 | 8250410.5881 | 8044178.8868 | 8248904.2671 | 0.00710323974999952 | |||||
| serine | 1104786.4555 | 1119021.7975 | 876947.7945 | 1040806.226 | 1019099.0921 | 1035487.309 | 984492.9866 | 1140070.9737 | 0.00710323974999952 | |||||
| similar to Inositol (6TMS)317 | 22856.3143 | 21400.1739 | 26879.4712 | 20769.2629 | 21220.2532 | 23534.2115 | 24747.1628 | 24475.1042 | 0.00710323974999952 | |||||
| spermidine | 296176.856 | 212691.7977 | 232233.2569 | 157657.6852 | 152361.0638 | 167259.2468 | 140010.5813 | 195281.8337 | NA | |||||
| succinate | 10647.1944 | 10003.5958 | 9734.8386 | 7916.2094 | 8587.0721 | 8018.1466 | 7442.4486 | 7588.902 | 0.00710323974999952 | |||||
| threonine | 420991.5518 | 429916.1531 | 357770.6463 | 359700.6462 | 356285.691 | 379011.0554 | 364032.017 | 407919.3535 | 0.00710323974999952 | |||||
| Trehalose | 1897637.2138 | 1979377.3709 | 2081364.7918 | 1236156.3278 | 1847773.5201 | 1842393.634 | 1925106.376 | 1559283.55 | 1 | |||||
| tyrosine | 697375.2953 | 585602.8427 | 613646.0109 | 581950.3998 | 561321.4293 | 591920.1319 | 469244.2233 | 643940.997 | NA | |||||
| Unknown_bth-pae-025_1411.4 | 125158.7943 | 110173.7689 | 120706.2892 | 121463.5382 | 91440.3057 | 107095.2461 | 95337.8071 | 99268.6977 | 0.00710323974999952 | |||||
| Unknown_bth-pae-039_1586.9 | 20220.5521 | 20317.5712 | 23793.4618 | 16409.8144 | 18539.501 | 22655.8217 | 22678.5544 | 20191.7852 | 0.00710323974999952 | |||||
| Unknown_cja-ppu-010_1366.59 | 7787.8708 | 7050.8219 | 8992.8916 | 8941.494 | 8587.274 | 10357.6747 | 10332.4676 | 10299.7444 | 0.00710323974999952 | |||||
| Unknown_Sso_jwo_013 | 22721.7034 | 21100.2696 | 26936.8812 | 22132.3982 | 21970.2597 | 22965.6974 | 24131.3688 | 23581.3879 | 0.103613619183413 | |||||
| Unknown_Sso_jwo_025 | 133645.588 | 116363.8302 | 127928.336 | 101329.4219 | 98125.9941 | 112994.4359 | 113551.9829 | 108359.6941 | NA | |||||
| Unknown_sst-cgl-004_1193.1 | 12734.5211 | 9306.8711 | 11666.4377 | 9320.7905 | 9834.4953 | 10240.8446 | 10861.6385 | 9761.3147 | NA | |||||
| Unknown_sst-cgl-023_1411.8 | 17939.6352 | 12206.9693 | 16069.068 | 9427.8159 | 7999.2109 | 10589.5911 | 8577.2785 | 9235.6493 | NA | |||||
| valine | 1006985.1984 | 905173.155 | 848781.0636 | 809699.7601 | 767863.9965 | 922696.4595 | 804562.6969 | 878703.6907 | 0.00710323974999952 | |||||
| Normalized peak area | ||||||||||||||
| Cultivation 1 | Cultivation 2 | Cultivation 3 | ||||||||||||
| Compound | CasAA:1 | CasAA:2 | CasAA:3 | CasAA:4 | CasAA:5 | CasAA:6 | CasAA:7 | CasAA:8 | CasAA:9 | p-value adjusted | ||||
| 2,3-dehydroadipyl-CoA | 50030.344203705434 | 54642.19758789212 | 54653.330754917784 | 37789.902588765144 | 36451.19126996398 | 47687.417987406894 | 66754.05283986621 | 72376.19198822544 | 71762.12933862278 | NA | ||||
| 2-Methylbutanoyl-CoA | 1898366.7025338076 | 794801.085442185 | 1539867.7815704492 | 1628321.4971526621 | 589263.1773027369 | 753369.6625020301 | 1761912.935237741 | 778474.8834558635 | 634543.0753312514 | 0.00180133797628942 | ||||
| 3-Hydroxy-2-methylbutyryl-CoA | 974747.8461835564 | 1115255.2318857997 | 986970.4844672201 | 867150.3160950786 | 1020771.503125165 | 1011084.4737799756 | 950034.7858544607 | 1019163.6593984361 | 1063727.8344101536 | 0.00180133797628942 | ||||
| 3-Hydroxybutanoyl-CoA | 31389.131340013024 | 41270.70741330105 | 31277.276916524577 | 22009.431238950405 | 23423.34610510928 | 38924.78906883154 | 29399.708140383955 | 42448.34507795464 | 50075.299933603 | 0.00180133797628942 | ||||
| 3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde | 30968.230498091285 | 24571.45199707561 | 31473.832837199185 | 28414.58962978851 | 32527.297458765508 | 22689.988053264235 | 31100.823066890265 | 35244.37575304121 | 24177.318391531222 | NA | ||||
| Acetyl-CoA | 3594403.487475085 | 4043223.4352986934 | 3895048.550043811 | 3800881.659551849 | 4280313.802445158 | 4082533.514312374 | 3982691.3543692986 | 4697315.3761508195 | 4589119.325030134 | 1 | ||||
| Beta-methylcrotonyl-CoA | 997347.3453371916 | 1091571.3744909153 | 927018.5646518492 | 889976.9910869845 | 943371.3736073973 | 1069891.2672916702 | 954575.584828999 | 1107886.790468508 | 1089609.1481685967 | NA | ||||
| b-Hydroxy-b-methylglutaryl CoA | 27228.325760335258 | 15008.302726216907 | 24939.863108604346 | 44215.28281315779 | 58049.08540680174 | 47133.68328269355 | 41400.10817150881 | 24827.430726918847 | 41220.94681458598 | 0.00180133797628942 | ||||
| Butanoyl-CoA | 71937.01884229359 | 70616.00230647597 | 48279.80570852053 | 40686.16484754296 | 50732.96104455862 | 69248.62732811915 | 77499.8570951447 | 85789.3344497939 | 92645.8715707669 | 1 | ||||
| CoenzymeA | 574089.564991818 | 571304.5960471749 | 548436.9980824109 | 611630.8610779879 | 561600.0058298452 | 554631.9623937259 | 341545.35258983454 | 402953.71714456327 | 451102.2287609374 | 0.0169792747475359 | ||||
| Isobutanoyl-CoA | 1187165.144278668 | 1306885.4310795546 | 1096558.9596445078 | 1162601.9471130213 | 1153722.2945176233 | 1286961.302048073 | 1232819.5058125549 | 1272821.4013632606 | 1314920.163128194 | 0.00180133797628942 | ||||
| Isovaleryl-CoA | 1268919.1453828476 | 1329975.4951192944 | 964604.7991360703 | 1035429.3050442842 | 965136.2180475716 | 1215534.1278112836 | 1188218.676902198 | 1180909.1228820006 | 1116974.5649318253 | 0.142731239125703 | ||||
| Methylmalonyl-CoA | 1713487.5581324715 | 1823015.8151033192 | 1953143.192310033 | 1950266.2290406052 | 2119629.3915152554 | 1861641.1967316172 | 1628081.3636141939 | 1582711.889303844 | 1704076.8935938962 | 0.00180133797628942 | ||||
| Phenylacetyl-CoA | 815037.8762072312 | 984589.7606058765 | 917517.6386467575 | 845236.3871030278 | 1072668.1756949164 | 1034616.4891097853 | 887741.9048957266 | 996830.8970751659 | 1015327.423115417 | 0.00180133797628942 | ||||
| Propanoyl-CoA | 533191.3286678727 | 585170.1373059899 | 642139.9792571502 | 621852.8380746847 | 712726.5898087552 | 683279.4848882827 | 576998.9088929433 | 571745.7565196438 | 586502.642109181 | 0.0058265589753608 | ||||
| Succinyl-CoA | 310036.8702039999 | 318883.9996661185 | 351214.6711079407 | 369718.08084715094 | 391963.44915650145 | 361040.68674320896 | 301655.53842401126 | 344008.186451735 | 339763.7312700569 | 0.00180133797628942 | ||||
A
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| Normalized peak area | Analysis is based on three independent biological replicates for each condition | ||||||||||||||
| Cultivation 1 | Cultivation 2 | Cultivation 3 | ND | not detected | |||||||||||
| Compound | Glc:1 | Glc:2 | Glc:3 | Glc:4 | Glc:5 | Glc:6 | Glc:7 | p-value adjusted | NA | not available (compound found on only one condition) | |||||
| 1-O-methyl-, alpha-galactopyranoside | 14484.4917 | 5546.9971 | 8661.656 | 9014.8822 | 9128.8942 | 6160.5685 | 5841.5906 | NA | |||||||
| 1-O-methyl-alpha-glucopyranoside | 429161.2121 | 103197.8124 | 186758.2995 | 198163.166 | 172419.711 | 97414.432 | 115271.8552 | 0.00710323974999952 | |||||||
| 2-hydroxyglutarate | 8251.6474 | 6712.756 | 7636.4962 | 3781.9683 | 3858.1059 | 3614.4481 | ND | 0.00710323974999952 | |||||||
| 2-methylmalate | 13388.2167 | 12348.4715 | 12997.7125 | 6719.119 | 6590.0947 | 6288.4618 | 13540.0755 | NA | |||||||
| 4-hydroxyphenylacetate | 44207.6071 | 37758.5719 | 40536.8612 | 133341.9484 | 126902.2992 | 131072.0696 | 62270.3625 | 0.00710323974999952 | |||||||
| alpha-D-Galactopyranosyl-(1,4)-D-galactopyranoside | 12592.484 | 13082.4752 | 13310.5244 | 11015.4072 | 10598.2665 | 13328.4992 | 20364.712 | NA | |||||||
| aspartate | 6267.0178 | 3506.8762 | 5250.6195 | 5593.5911 | 4819.2023 | 4644.2175 | 9646.6309 | 0.00710323974999952 | |||||||
| beta-Alanine | 2016.5106 | 1720.2407 | 1967.172 | 946.0804 | 858.7512 | 823.4066 | 2019.9058 | NA | |||||||
| cyanamide | 513302.9797 | 518981.872 | 534212.7902 | 523966.5174 | 508007.2676 | 568262.9573 | 896520.5085 | 0.00710323974999952 | |||||||
| D223156_2236.82 | 2035.8711 | 2136.2423 | 2358.1785 | 1452.6049 | 1224.6099 | 1383.1759 | 23088.7483 | NA | |||||||
| erythritol | 25641.4184 | 22681.0333 | 25696.4599 | 14120.3301 | 13549.8923 | 13220.6286 | 20986.0447 | NA | |||||||
| erythronic acid | 20208.9975 | 17731.5423 | 19934.1164 | 17773.3798 | 17511.4639 | 16665.1017 | 1945.4621 | NA | |||||||
| fumarate | 3072.3717 | 2223.1297 | 2763.315 | 3451.559 | 3435.6337 | 2962.2483 | 2492.2974 | 0.00710323974999952 | |||||||
| Glucopyranose_[-H20]_(4TMS)_1763.61 | 89227.0224 | 100734.6155 | 102245.6688 | 104852.2248 | 111440.4888 | 111507.3039 | ND | 1 | |||||||
| glucose | 751155.7195 | 733730.2631 | 774855.0565 | 876306.2541 | 1222005.3969 | 826420.6527 | 327566.8199 | 0.00710323974999952 | |||||||
| glutamate | 42880.0434 | 29321.7778 | 38061.7732 | 23017.0091 | 19136.2866 | 22217.9185 | 46217.9129 | 0.00710323974999952 | |||||||
| glycerate | 3462.0152 | 2827.8076 | 3220.7847 | 1986.0309 | 1906.6529 | 1809.4163 | 2719.7625 | 0.00710323974999952 | |||||||
| glycerol-3-phosphate | 1091395.3909 | 1055554.5655 | 1125622.5709 | 1088612.2801 | 1090037.722 | 1022100.8986 | 1425695.1102 | 0.00710323974999952 | |||||||
| glycine | 123280.939 | 112471.3724 | 126763.1392 | 136659.7484 | 146675.3103 | 135151.6127 | 116626.4202 | 0.00710323974999952 | |||||||
| glycolate | 2632.9479 | 2786.5079 | 2406.9369 | 2430.3888 | 1985.5822 | 2585.2982 | 2897.8592 | 0.239241817090161 | |||||||
| isoleucine | 74120.6123 | 67081.7268 | 75343.9965 | 58464.8314 | 52506.0413 | 62197.3275 | 105099.6207 | 0.00710323974999952 | |||||||
| leucine | 89833.3819 | 77769.6024 | 87779.0385 | 79847.8635 | 72663.2067 | 77034.1237 | 107782.305 | 0.00710323974999952 | |||||||
| malate | 2008.9504 | 2033.2752 | 2353.2642 | 3435.0969 | 3675.7365 | 3202.7107 | ND | 0.00710323974999952 | |||||||
| myo-inositol | 28622.6286 | 25550.2284 | 28480.8585 | 20970.1049 | 20768.3852 | 19934.3043 | 43912.16 | 0.00710323974999952 | |||||||
| NA_2615.1 | 79037.6987 | 62362.1067 | 70194.4036 | 52170.6868 | 70000.6239 | 47903.3075 | 166246.8482 | 0.757007456892091 | |||||||
| NA168015_1687.88 | 4346.3486 | 4684.7834 | 5305.4887 | 5400.3377 | 5311.1887 | 6396.3964 | 3614.7748 | 0.00710323974999952 | |||||||
| NA192001 | 2394.7692 | 1924.731 | 2259.349 | 2916.8936 | 5119.045 | 2391.1811 | 7799.5969 | 0.0314352099570089 | |||||||
| NA226 | 20432.7321 | 19197.8085 | 20254.8174 | 19801.4417 | 22788.2181 | 19506.6032 | ND | 0.103613619183413 | |||||||
| NA235 | 47769.4578 | 52103.1861 | 52391.6508 | 63124.4693 | 97283.1563 | 61725.9217 | 20379.7239 | NA | |||||||
| NA283 | 3970.9 | 4416.6832 | 4124.5611 | 5772.9036 | 7412.224 | 4032.0408 | 7281.089 | 0.00710323974999952 | |||||||
| NA653 | 44558.0371 | 41504.5309 | 44097.9337 | 41777.2614 | 45827.6003 | 40985.4572 | 64997.0739 | NA | |||||||
| Nicotinamide | 14616.3885 | 13158.1645 | 14159.4337 | 11549.1432 | 12005.921 | 11786.4838 | 33560.9876 | 1 | |||||||
| nicotinic acid | 5176.6615 | 5855.5544 | 6248.0549 | 4903.8721 | 5117.8963 | 4817.391 | 10556.8938 | NA | |||||||
| palatinose | 953992.3823 | 707462.9151 | 866847.0189 | 534973.2545 | 640915.911 | 568881.6433 | 1671223.2168 | 0.497066381143027 | |||||||
| phenylalanine | 5086.2336 | 2756.8764 | 3978.196 | 4483.1521 | 3878.0843 | 3860.8897 | 6183.6071 | 0.00710323974999952 | |||||||
| propane-1,3-diamine | 3740.6422 | 3251.7745 | 3414.0403 | 3117.8832 | 4025.8496 | 2581.2331 | 5109.772 | 0.0583537092643266 | |||||||
| putrescine | 214881.4381 | 128607.1972 | 149032.1548 | 212575.6321 | 223030.3884 | 163444.4626 | 330411.8113 | 0.0583537092643266 | |||||||
| pyroglutamate | 204618.2866 | 129992.4423 | 146869.2136 | 105972.8085 | 95269.0613 | 88167.9663 | 181263.8078 | 0.00710323974999952 | |||||||
| serine | 14727.9805 | 11507.9444 | 13898.3974 | 12632.7348 | 13367.8751 | 12475.9634 | 19562.0553 | 0.00710323974999952 | |||||||
| similar to Inositol (6TMS)317 | 3003.1329 | 2743.0944 | 3017.7976 | 2714.3241 | 2691.5872 | 2554.6273 | 3711.6259 | 0.00710323974999952 | |||||||
| succinate | 3206.9941 | 2834.4377 | 3365.25 | 2752.9733 | 2779.3327 | 2447.8541 | 1995.2081 | 0.00710323974999952 | |||||||
| threonine | 16795.6089 | 14473.9252 | 16469.8699 | 17614.9789 | 17855.0287 | 16569.1401 | 23861.0489 | 0.00710323974999952 | |||||||
| Trehalose | 1789082.7549 | 1433181.5469 | 1793717.8373 | 1669945.8434 | 1440007.0312 | 2396074.8597 | 2850648.8494 | 1 | |||||||
| Unknown_bth-pae-024_1385.3 | 1976.3737 | 1232.9358 | 4537.252 | 1571.0687 | 3404.7467 | 3229.2881 | ND | NA | |||||||
| Unknown_bth-pae-025_1411.4 | 76537.6474 | 70116.0016 | 75543.3756 | 58324.7782 | 59540.807 | 63792.0563 | 76194.925 | 0.00710323974999952 | |||||||
| Unknown_bth-pae-039_1586.9 | 9335.6635 | 9858.6179 | 8735.5809 | 9239.5416 | 8175.1076 | 7396.812 | 13225.1288 | 0.00710323974999952 | |||||||
| Unknown_cja-ppu-010_1366.59 | 21564.4546 | 19983.0056 | 22134.0725 | 21257.358 | 20902.6372 | 20225.3389 | 22939.8631 | 0.00710323974999952 | |||||||
| Unknown_Sso_jwo_003 | 26175.3792 | 22950.9472 | 27164.8313 | 32261.0067 | 34879.7513 | 29441.8378 | ND | NA | |||||||
| Unknown_Sso_jwo_013 | 19516.8921 | 18438.4963 | 20019.4739 | 20790.7224 | 21151.2278 | 19803.175 | 26271.4963 | 0.103613619183413 | |||||||
| valine | 20660.8925 | 17494.3086 | 20431.0573 | 14215.4859 | 17849.5065 | 12387.6512 | 26080.1304 | 0.00710323974999952 | |||||||
| xylitol | 37283.4854 | 28508.4037 | 36326.7449 | 34751.3056 | 32903.2044 | 25408.2427 | 32647.3566 | NA | |||||||
| xylulose | 44884.0099 | 38771.9785 | 43141.6804 | 47824.1614 | 47136.6874 | 46180.3086 | 2690.4426 | NA | |||||||
| Normalized peak area | |||||||||||||||
| Cultivation 1 | Cultivation 2 | Cultivation 3 | |||||||||||||
| Compound | Glc_1 | Glc_2 | Glc_3 | Glc_4 | Glc_5 | Glc_6 | Glc_7 | Glc_8 | Glc_9 | p-value adjusted | |||||
| 2-Methylbutanoyl-CoA | 73580.55690194694 | 73634.74466921335 | 83048.61598176633 | 51767.63896392025 | 54643.071653348255 | 49779.946072005136 | 50747.32620494822 | 60216.61144652615 | 58453.84178808307 | 0.00180133797628942 | |||||
| 2-Pentenoyl-CoA | 442851.41672614106 | 492270.4594941776 | 438310.64206402504 | 508509.5603414638 | 581799.2533204064 | 567885.5089225417 | 437773.67507868586 | 501473.2564096701 | 497444.712401471 | NA | |||||
| 3-Hydroxy-2-methylbutyryl-CoA | 4062389.3277660203 | 3965876.160845875 | 3978558.078313307 | 4768136.244957744 | 4773075.266338723 | 4645830.238798301 | 4003752.830599869 | 4034781.653929738 | 4059821.7475771364 | 0.00180133797628942 | |||||
| 3-Hydroxybutanoyl-CoA | 256201.23867775087 | 208234.77229519756 | 226506.41623241792 | 84033.4462158994 | 85483.26388232439 | 93533.27337130326 | 175733.0826783207 | 167013.44190035894 | 215443.67405250052 | 0.00180133797628942 | |||||
| Acetyl-CoA | 4242524.1619584365 | 4279490.62298748 | 4334762.518857791 | 3771267.2185122245 | 3839078.336041844 | 3874208.1710081487 | 4287599.749794307 | 4358829.395810931 | 4317158.734841321 | 1 | |||||
| Benzoyl-CoA | 92874.25658063445 | 100080.51485711019 | 93382.29623683766 | 151768.0384795603 | 147784.57276896675 | 138392.0143590044 | 169234.01337242243 | 178929.33365851679 | 144966.42286497858 | NA | |||||
| b-Hydroxy-b-methylglutaryl CoA | 1291233.722129891 | 1347994.7445418672 | 1159367.427730526 | 1132920.0324774731 | 986208.4849539542 | 1065026.9642531418 | 1257816.271953611 | 1290530.2984289024 | 1268906.1575198593 | 0.00180133797628942 | |||||
| Butanoyl-CoA | 107419.05802350609 | 110310.99823251611 | 150027.92764126373 | 38741.287400203204 | 38504.437995352695 | 42852.365566129956 | 66722.9276762408 | 48701.5741403596 | 63783.30054970303 | 1 | |||||
| CoenzymeA | 427221.07662847324 | 482313.8208360797 | 545139.3597683553 | 290512.35037922603 | 229554.69519354397 | 267160.5454581356 | 228011.44088516262 | 195577.39966387965 | 275084.286942296 | 0.0169792747475359 | |||||
| Hexanoyl-CoA | 61813.73176959185 | 71185.13786625431 | 109781.99270527913 | 28688.659351595536 | 12430.136173877107 | 31113.908191072478 | 41732.20411897357 | 34637.14446726992 | 29488.29439084292 | NA | |||||
| Isobutanoyl-CoA | 103382.57110532999 | 102599.158673452 | 107501.22777786193 | 83486.53549758444 | 84826.10046006224 | 94838.15264013439 | 166132.57994160434 | 116696.11902524455 | 101553.00166871569 | 0.00180133797628942 | |||||
| Isovaleryl-CoA | 1122111.0020276331 | 1181923.2608317903 | 1140263.6197479446 | 1405242.0173373157 | 1504505.459943503 | 1480493.1496433495 | 1446669.187517559 | 1302530.11888219 | 1258440.1177418255 | 0.142731239125703 | |||||
| Methylmalonyl-CoA | 167830.8443263248 | 165074.95446013942 | 144696.18011786244 | 187535.53869878463 | 173141.9605986005 | 181742.56567056847 | 177652.85257405875 | 192290.36825738018 | 159644.73953550615 | 0.00180133797628942 | |||||
| Phenylacetyl-CoA | 23097.628700828307 | 17183.89043535811 | 27922.685267483037 | 18508.800159067043 | 21437.486076576195 | 10852.615743802768 | 24674.762916484164 | 12939.754453498914 | 31543.735042659053 | 0.00180133797628942 | |||||
| Propanoyl-CoA | 575048.3462175726 | 518961.30334171996 | 526167.0002578994 | 506918.22897427075 | 489963.7664233243 | 501555.89566475956 | 521397.39093149226 | 550183.7063605859 | 538123.9146073665 | 0.0058265589753608 | |||||
| Succinyl-CoA | 547960.465536286 | 546401.5678493121 | 576038.9423055227 | 660930.660426286 | 719577.6704388426 | 692126.11611022 | 593089.5963263401 | 669709.5577004036 | 652042.7481330315 | 0.00180133797628942 | |||||
