<?xml version="1.0" encoding="UTF-8"?> <sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" level="3" version="1"> <model id="U2019_3" name="U2019_3" substanceUnits="substance" timeUnits="time_unit" volumeUnits="volume" areaUnits="area" lengthUnits="length" extentUnits="extent"> <listOfUnitDefinitions> <unitDefinition id="substance" name="nM (default)"> <listOfUnits> <unit kind="mole" exponent="1" scale="-9" multiplier="1"/> </listOfUnits> </unitDefinition> <unitDefinition id="extent"> <listOfUnits> <unit kind="mole" exponent="1" scale="-9" multiplier="1"/> </listOfUnits> </unitDefinition> <unitDefinition id="time_unit" name="hour (default)"> <listOfUnits> <unit kind="second" exponent="1" scale="3" multiplier="3.6"/> </listOfUnits> </unitDefinition> <unitDefinition id="area"> <listOfUnits> <unit kind="metre" exponent="2" scale="0" multiplier="1"/> </listOfUnits> </unitDefinition> <unitDefinition id="length"> <listOfUnits> <unit kind="metre" exponent="1" scale="0" multiplier="1"/> </listOfUnits> </unitDefinition> <unitDefinition id="volume"> <listOfUnits> <unit kind="litre" exponent="1" scale="0" multiplier="1"/> </listOfUnits> </unitDefinition> </listOfUnitDefinitions> <listOfCompartments> <compartment id="cell" spatialDimensions="3" size="1" constant="true"/> </listOfCompartments> <listOfSpecies> <species id="cL_m" compartment="cell" initialConcentration="49.192476092821" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cL" compartment="cell" initialConcentration="19533.8310652939" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cLmod" compartment="cell" initialConcentration="8150.22054965586" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP" compartment="cell" initialConcentration="1.97436241658655e-42" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP9_m" compartment="cell" initialConcentration="0.213314427682685" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP9" compartment="cell" initialConcentration="352.668641024508" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP7_m" compartment="cell" initialConcentration="4.56739071270852" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP7" compartment="cell" initialConcentration="5874.97410210038" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP5_m" compartment="cell" initialConcentration="1.62834213617423" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cP5" compartment="cell" initialConcentration="12683.8948734885" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cT_m" compartment="cell" initialConcentration="15.8361406037331" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cT" compartment="cell" initialConcentration="14503.8176761878" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cE4_m" compartment="cell" initialConcentration="12.0931816761446" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cE4" compartment="cell" initialConcentration="9587.14673565149" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cE3_m" compartment="cell" initialConcentration="34.2766722813638" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cE3c" compartment="cell" initialConcentration="9212.33015518463" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cE3n" compartment="cell" initialConcentration="2488.53477931516" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cLUX_m" compartment="cell" initialConcentration="12.0931816761446" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cLUX" compartment="cell" initialConcentration="49965.5773369801" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cCOP1c" compartment="cell" initialConcentration="0.23" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cCOP1n" compartment="cell" initialConcentration="0.276" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cCOP1d" compartment="cell" initialConcentration="0.0920000000003795" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cEGc" compartment="cell" initialConcentration="530.047804103971" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cEC" compartment="cell" initialConcentration="7883.1682456967" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cZTL" compartment="cell" initialConcentration="6323.48089150664" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cZG" compartment="cell" initialConcentration="18083.4327227666" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cG_m" compartment="cell" initialConcentration="5.28138370593544" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cGc" compartment="cell" initialConcentration="34.1471628685757" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cGn" compartment="cell" initialConcentration="107.772736674339" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cEGn" compartment="cell" initialConcentration="364.113477804229" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> <species id="cE34" compartment="cell" initialConcentration="4922.42832208483" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/> </listOfSpecies> <listOfParameters> <parameter id="cGn_tot" value="471.886214478568" constant="false"/> <parameter id="q1" value="224.070236452074" constant="true"/> <parameter id="L" value="1" constant="false"/> <parameter id="gml" value="1" constant="true"/> <parameter id="n1" value="1012.37718630491" constant="true"/> <parameter id="gp7" value="1" constant="true"/> <parameter id="g1" value="6709.15294882555" constant="true"/> <parameter id="m1" value="0.472478224440627" constant="true"/> <parameter id="m2" value="0.270383383879274" constant="true"/> <parameter id="p2" value="135.121073018697" constant="true"/> <parameter id="p1" value="97.9092290456145" constant="true"/> <parameter id="gl" value="1" constant="true"/> <parameter id="m3" value="0.209726654834423" constant="true"/> <parameter id="p3" value="15230.6518166006" constant="true"/> <parameter id="g3" value="44194.9042058677" constant="true"/> <parameter id="p7" value="0.3" constant="true"/> <parameter id="m11" value="1" constant="true"/> <parameter id="q3" value="175.758127101537" constant="true"/> <parameter id="gm9" value="1" constant="true"/> <parameter id="ge3" value="1" constant="true"/> <parameter id="g8" value="407.963202944501" constant="true"/> <parameter id="n4" value="3.79395856628938" constant="true"/> <parameter id="n7" value="14.2167613360537" constant="true"/> <parameter id="g9" value="33341.5724338571" constant="true"/> <parameter id="m12" value="1.51872508902782" constant="true"/> <parameter id="p8" value="501.185004935321" constant="true"/> <parameter id="m13" value="0.500914464916436" constant="true"/> <parameter id="m22" value="0.0624119331983405" constant="true"/> <parameter id="n8" value="18.403678260775" constant="true"/> <parameter id="g10" value="67504.9266768149" constant="true"/> <parameter id="gm7" value="1" constant="true"/> <parameter id="n9" value="5.88499980572144" constant="true"/> <parameter id="g11" value="59994.4134510773" constant="true"/> <parameter id="m14" value="0.440879974257324" constant="true"/> <parameter id="p9" value="1306.03706049707" constant="true"/> <parameter id="m15" value="0.982634835562064" constant="true"/> <parameter id="m23" value="1.48057704025775" constant="true"/> <parameter id="n10" value="5.01512745875978" constant="true"/> <parameter id="g12" value="16905.4687882644" constant="true"/> <parameter id="gm5" value="1" constant="true"/> <parameter id="n11" value="6.69496958196885" constant="true"/> <parameter id="g13" value="81139.5205326038" constant="true"/> <parameter id="m16" value="0.632510327340643" constant="true"/> <parameter id="p10" value="3785.33377795467" constant="true"/> <parameter id="m17" value="0.606609704046493" constant="true"/> <parameter id="m24" value="0.0766744701909765" constant="true"/> <parameter id="n2" value="74.5202814722954" constant="true"/> <parameter id="g4" value="451.307347445099" constant="true"/> <parameter id="g5" value="20979.0088169331" constant="true"/> <parameter id="gmt" value="1" constant="true"/> <parameter id="m5" value="0.365603548533465" constant="true"/> <parameter id="p4" value="421.239269572391" constant="true"/> <parameter id="m6" value="0.106923346685408" constant="true"/> <parameter id="m7" value="0.202204789877226" constant="true"/> <parameter id="p5" value="0.000354705315701364" constant="true"/> <parameter id="dZG" value="29717.820753307" constant="true"/> <parameter id="m8" value="0.386558514560172" constant="true"/> <parameter id="n13" value="123.397741207481" constant="true"/> <parameter id="g2" value="595.533664539628" constant="true"/> <parameter id="g6" value="24508.1233035278" constant="true"/> <parameter id="gm4" value="1" constant="true"/> <parameter id="m34" value="0.639825570593053" constant="true"/> <parameter id="p23" value="145.407042727037" constant="true"/> <parameter id="m35" value="0.247772032610646" constant="true"/> <parameter id="p25" value="0.000596694067670263" constant="true"/> <parameter id="p21" value="2.65390547631073" constant="true"/> <parameter id="n3" value="17.9030199538489" constant="true"/> <parameter id="g16" value="28140.6558736504" constant="true"/> <parameter id="gm3" value="1" constant="true"/> <parameter id="m26" value="0.412244305031997" constant="true"/> <parameter id="p16" value="779.163539265197" constant="true"/> <parameter id="m9" value="5.23628610457024" constant="true"/> <parameter id="p17" value="0.00214229640781567" constant="true"/> <parameter id="p19" value="1.69252446195173" constant="true"/> <parameter id="p20" value="0.0857149842402559" constant="true"/> <parameter id="m30" value="13.0722781787554" constant="true"/> <parameter id="m29" value="15.4767161839369" constant="true"/> <parameter id="p27" value="778.696270935226" constant="true"/> <parameter id="m39" value="0.394230519151613" constant="true"/> <parameter id="p26" value="6.03985788533193e-06" constant="true"/> <parameter id="n5" value="0.23" constant="true"/> <parameter id="p6" value="0.6" constant="true"/> <parameter id="m27" value="0.1" constant="true"/> <parameter id="p15" value="3" constant="true"/> <parameter id="n6" value="20" constant="true"/> <parameter id="n14" value="0.1" constant="true"/> <parameter id="m31" value="0.3" constant="true"/> <parameter id="m33" value="13" constant="true"/> <parameter id="p18" value="0.236910457951958" constant="true"/> <parameter id="p31" value="0.140795715737152" constant="true"/> <parameter id="m36" value="0.0988627559324387" constant="true"/> <parameter id="m37" value="0.638671244532235" constant="true"/> <parameter id="m32" value="0.17786749055661" constant="true"/> <parameter id="p24" value="11.2645147978309" constant="true"/> <parameter id="g7" value="5921.57714493994" constant="true"/> <parameter id="p14" value="8067.52567269685" constant="true"/> <parameter id="p12" value="0.00102393968696542" constant="true"/> <parameter id="p13" value="0.0765570658950953" constant="true"/> <parameter id="m20" value="1.23924716050164" constant="true"/> <parameter id="m21" value="0.0800304547984497" constant="true"/> <parameter id="q2" value="149.393841965426" constant="true"/> <parameter id="gmg" value="1" constant="true"/> <parameter id="n12" value="1047.3417892582" constant="true"/> <parameter id="g14" value="206.415896126819" constant="true"/> <parameter id="g15" value="42247.3454001201" constant="true"/> <parameter id="m18" value="4.17528060369758" constant="true"/> <parameter id="p11" value="310.101956731595" constant="true"/> <parameter id="m19" value="1.18499836603551" constant="true"/> <parameter id="p28" value="21.5197740727555" constant="true"/> <parameter id="p29" value="0.305804164480483" constant="true"/> <parameter id="m10" value="4.16475304417486" constant="true"/> <parameter id="cEG" value="0.00381490790681182" constant="true"/> <parameter id="m4" value="0.2" constant="true"/> </listOfParameters> <listOfInitialAssignments> <initialAssignment symbol="cL_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 1.05129004396331 </cn> <cn> 240.398303596736 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cP9_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.0656063461084473 </cn> <cn> 69.5228161344057 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cP7_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.429686087062748 </cn> <cn> 36.7151462664629 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cP5_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.778001394975754 </cn> <cn> 10.8150058554228 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cT_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.0928798167556545 </cn> <cn> 98.7139376747197 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cE4_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.0949886368399 </cn> <cn> 59.100196230293 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cE3_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.282857048667234 </cn> <cn> 37.4270777712061 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cLUX_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.0949886368399 </cn> <cn> 59.100196230293 </cn> </apply> </math> </initialAssignment> <initialAssignment symbol="cG_m"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <cn> 0.096830093091897 </cn> <cn> 71.2315112597985 </cn> </apply> </math> </initialAssignment> </listOfInitialAssignments> <listOfRules> <assignmentRule variable="cGn_tot"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <plus/> <ci> cGn </ci> <ci> cEGn </ci> </apply> </math> </assignmentRule> </listOfRules> <listOfReactions> <reaction id="cL_m_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cL_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cP"/> <modifierSpeciesReference species="cP7"/> <modifierSpeciesReference species="cT"/> <modifierSpeciesReference species="cP9"/> <modifierSpeciesReference species="cP5"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <ci> q1 </ci> <ci> L </ci> <ci> cP </ci> <ci> gml </ci> </apply> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n1 </ci> <apply> <power/> <ci> gp7 </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g1 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gp7 </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g1 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <apply> <plus/> <ci> cP9 </ci> <ci> cP7 </ci> <ci> cP5 </ci> <ci> cT </ci> </apply> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gml </ci> </apply> </apply> <apply> <times/> <apply> <plus/> <apply> <times/> <ci> m1 </ci> <ci> L </ci> </apply> <apply> <times/> <ci> m2 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <ci> cL_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cL_m_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cL" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <apply> <times/> <apply> <divide/> <apply> <times/> <apply> <plus/> <ci> p2 </ci> <apply> <times/> <ci> p1 </ci> <ci> L </ci> </apply> </apply> <ci> cL_m </ci> </apply> <ci> gml </ci> </apply> <ci> gl </ci> </apply> <apply> <times/> <ci> m3 </ci> <ci> cL </ci> </apply> </apply> <apply> <divide/> <apply> <times/> <ci> p3 </ci> <ci> gl </ci> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g3 </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cL_mod_pro" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cLmod" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> p3 </ci> <ci> gl </ci> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g3 </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> </apply> <apply> <times/> <ci> m3 </ci> <ci> cLmod </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP_prod" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP" stoichiometry="1" constant="true"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <ci> p7 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> cP </ci> </apply> </apply> <apply> <times/> <ci> m11 </ci> <ci> cP </ci> <ci> L </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP9_m_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP9_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> <modifierSpeciesReference species="cP"/> <modifierSpeciesReference species="cEC"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <ci> L </ci> <ci> q3 </ci> <ci> cP </ci> <ci> gm9 </ci> </apply> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> ge3 </ci> <ci> g8 </ci> </apply> <apply> <plus/> <apply> <times/> <ci> ge3 </ci> <ci> g8 </ci> </apply> <ci> cEC </ci> </apply> </apply> <apply> <plus/> <ci> n4 </ci> <apply> <divide/> <apply> <times/> <ci> n7 </ci> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g9 </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> </apply> </apply> <ci> gm9 </ci> </apply> </apply> <apply> <times/> <ci> m12 </ci> <ci> cP9_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP9_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP9" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cP9_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> gp7 </ci> <ci> p8 </ci> <ci> cP9_m </ci> </apply> <ci> gm9 </ci> </apply> <apply> <times/> <apply> <plus/> <ci> m13 </ci> <apply> <times/> <ci> m22 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <ci> cP9 </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP7_m_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP7_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> <modifierSpeciesReference species="cLmod"/> <modifierSpeciesReference species="cP9"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n8 </ci> <apply> <power/> <apply> <plus/> <ci> cL </ci> <ci> cLmod </ci> </apply> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g10 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <apply> <plus/> <ci> cL </ci> <ci> cLmod </ci> </apply> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm7 </ci> </apply> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n9 </ci> <apply> <power/> <ci> cP9 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gp7 </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g11 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cP9 </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm7 </ci> </apply> </apply> <apply> <times/> <ci> m14 </ci> <ci> cP7_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP7_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP7" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cP7_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> gp7 </ci> <ci> p9 </ci> <ci> cP7_m </ci> </apply> <ci> gm7 </ci> </apply> <apply> <times/> <apply> <plus/> <ci> m15 </ci> <apply> <times/> <ci> m23 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <ci> cP7 </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP5_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP5_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cP7"/> <modifierSpeciesReference species="cLmod"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n10 </ci> <apply> <power/> <ci> cLmod </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g12 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cLmod </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm5 </ci> </apply> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n11 </ci> <apply> <power/> <ci> cP7 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gp7 </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g13 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cP7 </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm5 </ci> </apply> </apply> <apply> <times/> <ci> m16 </ci> <ci> cP5_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cP5_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cP5" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cP5_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> gp7 </ci> <ci> p10 </ci> <ci> cP5_m </ci> </apply> <ci> gm5 </ci> </apply> <apply> <times/> <apply> <plus/> <ci> m17 </ci> <apply> <times/> <ci> m24 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <ci> cP5 </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cT_m_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cT_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> <modifierSpeciesReference species="cEC"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <apply> <divide/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n2 </ci> <ci> ge3 </ci> <ci> g4 </ci> </apply> <apply> <plus/> <apply> <times/> <ci> ge3 </ci> <ci> g4 </ci> </apply> <ci> cEC </ci> </apply> </apply> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g5 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g5 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gmt </ci> </apply> <apply> <times/> <ci> m5 </ci> <ci> cT_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cT_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cT" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cZTL"/> <modifierSpeciesReference species="cZG"/> <modifierSpeciesReference species="cT_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> gp7 </ci> <ci> p4 </ci> <ci> cT_m </ci> </apply> <ci> gmt </ci> </apply> <apply> <times/> <apply> <plus/> <ci> m6 </ci> <apply> <times/> <ci> m7 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <ci> cT </ci> <apply> <plus/> <apply> <divide/> <apply> <times/> <ci> cZTL </ci> <ci> p5 </ci> </apply> <ci> ge3 </ci> </apply> <apply> <divide/> <ci> cZG </ci> <apply> <times/> <ci> dZG </ci> <ci> ge3 </ci> </apply> </apply> </apply> </apply> </apply> <apply> <times/> <ci> m8 </ci> <ci> cT </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cE4_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cE4_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> <modifierSpeciesReference species="cEC"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <apply> <divide/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n13 </ci> <ci> ge3 </ci> <ci> g2 </ci> </apply> <apply> <plus/> <apply> <times/> <ci> ge3 </ci> <ci> g2 </ci> </apply> <ci> cEC </ci> </apply> </apply> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g6 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g6 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm4 </ci> </apply> <apply> <times/> <ci> m34 </ci> <ci> cE4_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cE4_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cE4" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cE4_m"/> <modifierSpeciesReference species="cE34"/> <modifierSpeciesReference species="cE3n"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <plus/> <apply> <minus/> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> p23 </ci> <ci> ge3 </ci> <ci> cE4_m </ci> </apply> <ci> gm4 </ci> </apply> <apply> <times/> <ci> m35 </ci> <ci> cE4 </ci> </apply> </apply> <apply> <times/> <apply> <divide/> <ci> p25 </ci> <ci> ge3 </ci> </apply> <ci> cE4 </ci> <ci> cE3n </ci> </apply> </apply> <apply> <times/> <ci> p21 </ci> <ci> cE34 </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cE3_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cE3_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n3 </ci> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g16 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g16 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm3 </ci> </apply> <apply> <times/> <ci> m26 </ci> <ci> cE3_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cE3c_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cE3c" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cE3_m"/> <modifierSpeciesReference species="cGc"/> <modifierSpeciesReference species="cCOP1c"/> <modifierSpeciesReference species="cE3n"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <plus/> <apply> <minus/> <apply> <minus/> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> p16 </ci> <ci> ge3 </ci> <ci> cE3_m </ci> </apply> <ci> gm3 </ci> </apply> <apply> <times/> <ci> m9 </ci> <ci> cE3c </ci> <ci> cCOP1c </ci> </apply> </apply> <apply> <times/> <apply> <divide/> <ci> p17 </ci> <ci> ge3 </ci> </apply> <ci> cE3c </ci> <ci> cGc </ci> </apply> </apply> <apply> <times/> <ci> p19 </ci> <ci> cE3c </ci> </apply> </apply> <apply> <times/> <ci> p20 </ci> <ci> cE3n </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cE3n_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cE3n" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cGn"/> <modifierSpeciesReference species="cCOP1n"/> <modifierSpeciesReference species="cCOP1d"/> <modifierSpeciesReference species="cE3c"/> <modifierSpeciesReference species="cE4"/> <modifierSpeciesReference species="cE34"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <minus/> <apply> <minus/> <apply> <minus/> <apply> <minus/> <apply> <times/> <ci> p19 </ci> <ci> cE3c </ci> </apply> <apply> <times/> <ci> p20 </ci> <ci> cE3n </ci> </apply> </apply> <apply> <times/> <apply> <divide/> <ci> p17 </ci> <ci> ge3 </ci> </apply> <ci> cE3n </ci> <ci> cGn </ci> </apply> </apply> <apply> <times/> <ci> m30 </ci> <ci> cE3n </ci> <ci> cCOP1d </ci> </apply> </apply> <apply> <times/> <ci> m29 </ci> <ci> cE3n </ci> <ci> cCOP1n </ci> </apply> </apply> <apply> <times/> <ci> p21 </ci> <ci> cE34 </ci> </apply> </apply> <apply> <times/> <apply> <divide/> <ci> p25 </ci> <ci> ge3 </ci> </apply> <ci> cE4 </ci> <ci> cE3n </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cLUX_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cLUX_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> <modifierSpeciesReference species="cEC"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <apply> <divide/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n13 </ci> <ci> ge3 </ci> <ci> g2 </ci> </apply> <apply> <plus/> <apply> <times/> <ci> ge3 </ci> <ci> g2 </ci> </apply> <ci> cEC </ci> </apply> </apply> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g6 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g6 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gm4 </ci> </apply> <apply> <times/> <ci> m34 </ci> <ci> cLUX_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cLUX_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cLUX" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cE34"/> <modifierSpeciesReference species="cLUX_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> p27 </ci> <ci> ge3 </ci> <ci> cLUX_m </ci> </apply> <ci> gm4 </ci> </apply> <apply> <times/> <ci> m39 </ci> <ci> cLUX </ci> </apply> </apply> <apply> <times/> <apply> <divide/> <ci> p26 </ci> <ci> ge3 </ci> </apply> <ci> cLUX </ci> <ci> cE34 </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cCOP1c_prod" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cCOP1c" stoichiometry="1" constant="true"/> </listOfProducts> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <ci> n5 </ci> <apply> <times/> <ci> p6 </ci> <ci> cCOP1c </ci> </apply> </apply> <apply> <times/> <ci> m27 </ci> <ci> cCOP1c </ci> <apply> <plus/> <cn type="integer"> 1 </cn> <apply> <times/> <ci> p15 </ci> <ci> L </ci> </apply> </apply> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cCOP1n_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cCOP1n" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cP"/> <modifierSpeciesReference species="cCOP1c"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <apply> <minus/> <apply> <times/> <ci> p6 </ci> <ci> cCOP1c </ci> </apply> <apply> <times/> <ci> n6 </ci> <ci> L </ci> <ci> cP </ci> <ci> cCOP1n </ci> </apply> </apply> <apply> <times/> <ci> n14 </ci> <ci> cCOP1n </ci> </apply> </apply> <apply> <times/> <ci> m27 </ci> <ci> cCOP1n </ci> <apply> <plus/> <cn type="integer"> 1 </cn> <apply> <times/> <ci> p15 </ci> <ci> L </ci> </apply> </apply> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cCOP1d_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cCOP1d" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cCOP1n"/> <modifierSpeciesReference species="cP"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <ci> n14 </ci> <ci> cCOP1n </ci> </apply> <apply> <times/> <ci> n6 </ci> <ci> L </ci> <ci> cP </ci> <ci> cCOP1n </ci> </apply> </apply> <apply> <times/> <ci> m31 </ci> <apply> <plus/> <cn type="integer"> 1 </cn> <apply> <times/> <ci> m33 </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <ci> cCOP1d </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cEGc_prod" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cEGc" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cEGn"/> <modifierSpeciesReference species="cE3c"/> <modifierSpeciesReference species="cGc"/> <modifierSpeciesReference species="cCOP1c"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <plus/> <apply> <minus/> <apply> <minus/> <apply> <times/> <apply> <divide/> <ci> p17 </ci> <ci> ge3 </ci> </apply> <ci> cE3c </ci> <ci> cGc </ci> </apply> <apply> <times/> <ci> m9 </ci> <ci> cEGc </ci> <ci> cCOP1c </ci> </apply> </apply> <apply> <times/> <ci> p18 </ci> <ci> cEGc </ci> </apply> </apply> <apply> <times/> <ci> p31 </ci> <ci> cEGn </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cEC_form" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cEC" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cCOP1n"/> <modifierSpeciesReference species="cCOP1d"/> <modifierSpeciesReference species="cE34"/> <modifierSpeciesReference species="cLUX"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <apply> <minus/> <apply> <times/> <apply> <divide/> <ci> p26 </ci> <ci> ge3 </ci> </apply> <ci> cLUX </ci> <ci> cE34 </ci> </apply> <apply> <times/> <ci> m36 </ci> <ci> cEC </ci> <ci> cCOP1n </ci> </apply> </apply> <apply> <times/> <ci> m37 </ci> <ci> cEC </ci> <ci> cCOP1d </ci> </apply> </apply> <apply> <times/> <ci> m32 </ci> <ci> cEC </ci> <apply> <plus/> <cn type="integer"> 1 </cn> <apply> <divide/> <apply> <times/> <ci> p24 </ci> <ci> L </ci> <apply> <power/> <ci> cGn_tot </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> ge3 </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g7 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cGn_tot </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> </apply> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cZTL_prod" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cZTL" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cZG"/> <modifierSpeciesReference species="cGc"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <minus/> <apply> <times/> <ci> ge3 </ci> <ci> p14 </ci> </apply> <apply> <times/> <apply> <divide/> <ci> p12 </ci> <ci> ge3 </ci> </apply> <ci> L </ci> <ci> cZTL </ci> <ci> cGc </ci> </apply> </apply> <apply> <times/> <ci> p13 </ci> <ci> cZG </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <apply> <times/> <ci> m20 </ci> <ci> cZTL </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cZG_prod" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cZG" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cZTL"/> <modifierSpeciesReference species="cGc"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <minus/> <apply> <times/> <apply> <divide/> <ci> p12 </ci> <ci> ge3 </ci> </apply> <ci> L </ci> <ci> cZTL </ci> <ci> cGc </ci> </apply> <apply> <times/> <ci> p13 </ci> <ci> cZG </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <apply> <times/> <ci> m21 </ci> <ci> cZG </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cG_m_trscr" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cG_m" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cL"/> <modifierSpeciesReference species="cP"/> <modifierSpeciesReference species="cEC"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <ci> L </ci> <ci> q2 </ci> <ci> cP </ci> <ci> gmg </ci> </apply> <apply> <times/> <apply> <divide/> <apply> <times/> <apply> <divide/> <apply> <times/> <ci> n12 </ci> <ci> ge3 </ci> <ci> g14 </ci> </apply> <apply> <plus/> <apply> <times/> <ci> ge3 </ci> <ci> g14 </ci> </apply> <ci> cEC </ci> </apply> </apply> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g15 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <plus/> <apply> <times/> <apply> <power/> <ci> gl </ci> <cn type="integer"> 2 </cn> </apply> <apply> <power/> <ci> g15 </ci> <cn type="integer"> 2 </cn> </apply> </apply> <apply> <power/> <ci> cL </ci> <cn type="integer"> 2 </cn> </apply> </apply> </apply> <ci> gmg </ci> </apply> </apply> <apply> <times/> <ci> m18 </ci> <ci> cG_m </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cG_trans" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cGc" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cZTL"/> <modifierSpeciesReference species="cZG"/> <modifierSpeciesReference species="cGn"/> <modifierSpeciesReference species="cE3c"/> <modifierSpeciesReference species="cG_m"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <plus/> <apply> <minus/> <apply> <minus/> <apply> <minus/> <apply> <plus/> <apply> <minus/> <apply> <divide/> <apply> <times/> <ci> p11 </ci> <ci> ge3 </ci> <ci> cG_m </ci> </apply> <ci> gmg </ci> </apply> <apply> <times/> <apply> <divide/> <ci> p12 </ci> <ci> ge3 </ci> </apply> <ci> L </ci> <ci> cZTL </ci> <ci> cGc </ci> </apply> </apply> <apply> <times/> <ci> p13 </ci> <ci> cZG </ci> <apply> <minus/> <cn type="integer"> 1 </cn> <ci> L </ci> </apply> </apply> </apply> <apply> <times/> <ci> m19 </ci> <ci> cGc </ci> </apply> </apply> <apply> <times/> <apply> <divide/> <ci> p17 </ci> <ci> ge3 </ci> </apply> <ci> cE3c </ci> <ci> cGc </ci> </apply> </apply> <apply> <times/> <ci> p28 </ci> <ci> cGc </ci> </apply> </apply> <apply> <times/> <ci> p29 </ci> <ci> cGn </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cGn_traspo" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cGn" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cGc"/> <modifierSpeciesReference species="cE3n"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <ci> p28 </ci> <ci> cGc </ci> </apply> <apply> <times/> <apply> <plus/> <ci> p29 </ci> <ci> m19 </ci> <apply> <times/> <apply> <divide/> <ci> p17 </ci> <ci> ge3 </ci> </apply> <ci> cE3n </ci> </apply> </apply> <ci> cGn </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cE34_compl" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cE34" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cCOP1n"/> <modifierSpeciesReference species="cCOP1d"/> <modifierSpeciesReference species="cE4"/> <modifierSpeciesReference species="cLUX"/> <modifierSpeciesReference species="cE3n"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <times/> <apply> <divide/> <ci> p25 </ci> <ci> ge3 </ci> </apply> <ci> cE4 </ci> <ci> cE3n </ci> </apply> <apply> <times/> <apply> <plus/> <apply> <times/> <apply> <divide/> <ci> p26 </ci> <ci> ge3 </ci> </apply> <ci> cLUX </ci> </apply> <ci> p21 </ci> <apply> <times/> <ci> m37 </ci> <ci> cCOP1d </ci> </apply> <apply> <times/> <ci> m36 </ci> <ci> cCOP1n </ci> </apply> </apply> <ci> cE34 </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> <reaction id="cEGn_tranp" reversible="false" fast="false"> <listOfProducts> <speciesReference species="cEGn" stoichiometry="1" constant="true"/> </listOfProducts> <listOfModifiers> <modifierSpeciesReference species="cGn"/> <modifierSpeciesReference species="cCOP1n"/> <modifierSpeciesReference species="cCOP1d"/> <modifierSpeciesReference species="cE3n"/> <modifierSpeciesReference species="cEGc"/> </listOfModifiers> <kineticLaw> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <times/> <ci> cell </ci> <apply> <minus/> <apply> <plus/> <apply> <times/> <ci> p18 </ci> <ci> cEGc </ci> </apply> <apply> <times/> <apply> <divide/> <ci> p17 </ci> <ci> ge3 </ci> </apply> <ci> cE3n </ci> <ci> cGn </ci> </apply> </apply> <apply> <times/> <apply> <plus/> <apply> <times/> <ci> m9 </ci> <ci> cCOP1n </ci> </apply> <apply> <times/> <ci> m10 </ci> <ci> cCOP1d </ci> </apply> <ci> p31 </ci> </apply> <ci> cEGn </ci> </apply> </apply> </apply> </math> </kineticLaw> </reaction> </listOfReactions> <listOfEvents> <event id="_E0" useValuesFromTriggerTime="true"> <trigger initialValue="true" persistent="true"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <and/> <apply> <geq/> <piecewise> <piece> <apply> <minus/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <apply> <ceiling/> <apply> <divide/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <cn type="integer"> 24 </cn> </apply> </apply> </apply> </apply> <apply> <xor/> <apply> <lt/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <cn type="integer"> 0 </cn> </apply> <apply> <lt/> <cn type="integer"> 24 </cn> <cn type="integer"> 0 </cn> </apply> </apply> </piece> <otherwise> <apply> <minus/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <apply> <floor/> <apply> <divide/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <cn type="integer"> 24 </cn> </apply> </apply> </apply> </apply> </otherwise> </piecewise> <cn type="integer"> 12 </cn> </apply> <apply> <lt/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <cn type="integer"> 11 </cn> </apply> </apply> </apply> </math> </trigger> <listOfEventAssignments> <eventAssignment variable="L"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <cn type="integer"> 0 </cn> </math> </eventAssignment> </listOfEventAssignments> </event> <event id="_E1" useValuesFromTriggerTime="true"> <trigger initialValue="true" persistent="true"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <and/> <apply> <lt/> <piecewise> <piece> <apply> <minus/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <apply> <ceiling/> <apply> <divide/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <cn type="integer"> 24 </cn> </apply> </apply> </apply> </apply> <apply> <xor/> <apply> <lt/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <cn type="integer"> 0 </cn> </apply> <apply> <lt/> <cn type="integer"> 24 </cn> <cn type="integer"> 0 </cn> </apply> </apply> </piece> <otherwise> <apply> <minus/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <apply> <floor/> <apply> <divide/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <cn type="integer"> 24 </cn> </apply> </apply> </apply> </apply> </otherwise> </piecewise> <cn type="integer"> 12 </cn> </apply> <apply> <lt/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <cn type="integer"> 11 </cn> </apply> </apply> </apply> </math> </trigger> <listOfEventAssignments> <eventAssignment variable="L"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <cn type="integer"> 1 </cn> </math> </eventAssignment> </listOfEventAssignments> </event> <event id="_E2" useValuesFromTriggerTime="true"> <trigger initialValue="true" persistent="true"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <apply> <geq/> <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol> <apply> <times/> <cn type="integer"> 24 </cn> <cn type="integer"> 11 </cn> </apply> </apply> </math> </trigger> <listOfEventAssignments> <eventAssignment variable="L"> <math xmlns="http://www.w3.org/1998/Math/MathML"> <cn type="integer"> 1 </cn> </math> </eventAssignment> </listOfEventAssignments> </event> </listOfEvents> </model> </sbml>