<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" level="3" version="1">
  <model id="U2019_3" name="U2019_3" substanceUnits="substance" timeUnits="time_unit" volumeUnits="volume" areaUnits="area" lengthUnits="length" extentUnits="extent">
    <listOfUnitDefinitions>
      <unitDefinition id="substance" name="nM (default)">
        <listOfUnits>
          <unit kind="mole" exponent="1" scale="-9" multiplier="1"/>
        </listOfUnits>
      </unitDefinition>
      <unitDefinition id="extent">
        <listOfUnits>
          <unit kind="mole" exponent="1" scale="-9" multiplier="1"/>
        </listOfUnits>
      </unitDefinition>
      <unitDefinition id="time_unit" name="hour (default)">
        <listOfUnits>
          <unit kind="second" exponent="1" scale="3" multiplier="3.6"/>
        </listOfUnits>
      </unitDefinition>
      <unitDefinition id="area">
        <listOfUnits>
          <unit kind="metre" exponent="2" scale="0" multiplier="1"/>
        </listOfUnits>
      </unitDefinition>
      <unitDefinition id="length">
        <listOfUnits>
          <unit kind="metre" exponent="1" scale="0" multiplier="1"/>
        </listOfUnits>
      </unitDefinition>
      <unitDefinition id="volume">
        <listOfUnits>
          <unit kind="litre" exponent="1" scale="0" multiplier="1"/>
        </listOfUnits>
      </unitDefinition>
    </listOfUnitDefinitions>
    <listOfCompartments>
      <compartment id="cell" spatialDimensions="3" size="1" constant="true"/>
    </listOfCompartments>
    <listOfSpecies>
      <species id="cL_m" compartment="cell" initialConcentration="49.192476092821" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cL" compartment="cell" initialConcentration="19533.8310652939" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cLmod" compartment="cell" initialConcentration="8150.22054965586" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP" compartment="cell" initialConcentration="1.97436241658655e-42" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP9_m" compartment="cell" initialConcentration="0.213314427682685" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP9" compartment="cell" initialConcentration="352.668641024508" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP7_m" compartment="cell" initialConcentration="4.56739071270852" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP7" compartment="cell" initialConcentration="5874.97410210038" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP5_m" compartment="cell" initialConcentration="1.62834213617423" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cP5" compartment="cell" initialConcentration="12683.8948734885" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cT_m" compartment="cell" initialConcentration="15.8361406037331" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cT" compartment="cell" initialConcentration="14503.8176761878" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cE4_m" compartment="cell" initialConcentration="12.0931816761446" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cE4" compartment="cell" initialConcentration="9587.14673565149" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cE3_m" compartment="cell" initialConcentration="34.2766722813638" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cE3c" compartment="cell" initialConcentration="9212.33015518463" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cE3n" compartment="cell" initialConcentration="2488.53477931516" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cLUX_m" compartment="cell" initialConcentration="12.0931816761446" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cLUX" compartment="cell" initialConcentration="49965.5773369801" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cCOP1c" compartment="cell" initialConcentration="0.23" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cCOP1n" compartment="cell" initialConcentration="0.276" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cCOP1d" compartment="cell" initialConcentration="0.0920000000003795" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cEGc" compartment="cell" initialConcentration="530.047804103971" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cEC" compartment="cell" initialConcentration="7883.1682456967" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cZTL" compartment="cell" initialConcentration="6323.48089150664" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cZG" compartment="cell" initialConcentration="18083.4327227666" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cG_m" compartment="cell" initialConcentration="5.28138370593544" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cGc" compartment="cell" initialConcentration="34.1471628685757" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cGn" compartment="cell" initialConcentration="107.772736674339" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cEGn" compartment="cell" initialConcentration="364.113477804229" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
      <species id="cE34" compartment="cell" initialConcentration="4922.42832208483" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false"/>
    </listOfSpecies>
    <listOfParameters>
      <parameter id="cGn_tot" value="471.886214478568" constant="false"/>
      <parameter id="q1" value="224.070236452074" constant="true"/>
      <parameter id="L" value="1" constant="false"/>
      <parameter id="gml" value="1" constant="true"/>
      <parameter id="n1" value="1012.37718630491" constant="true"/>
      <parameter id="gp7" value="1" constant="true"/>
      <parameter id="g1" value="6709.15294882555" constant="true"/>
      <parameter id="m1" value="0.472478224440627" constant="true"/>
      <parameter id="m2" value="0.270383383879274" constant="true"/>
      <parameter id="p2" value="135.121073018697" constant="true"/>
      <parameter id="p1" value="97.9092290456145" constant="true"/>
      <parameter id="gl" value="1" constant="true"/>
      <parameter id="m3" value="0.209726654834423" constant="true"/>
      <parameter id="p3" value="15230.6518166006" constant="true"/>
      <parameter id="g3" value="44194.9042058677" constant="true"/>
      <parameter id="p7" value="0.3" constant="true"/>
      <parameter id="m11" value="1" constant="true"/>
      <parameter id="q3" value="175.758127101537" constant="true"/>
      <parameter id="gm9" value="1" constant="true"/>
      <parameter id="ge3" value="1" constant="true"/>
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      <parameter id="n4" value="3.79395856628938" constant="true"/>
      <parameter id="n7" value="14.2167613360537" constant="true"/>
      <parameter id="g9" value="33341.5724338571" constant="true"/>
      <parameter id="m12" value="1.51872508902782" constant="true"/>
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      <parameter id="m13" value="0.500914464916436" constant="true"/>
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      <parameter id="n8" value="18.403678260775" constant="true"/>
      <parameter id="g10" value="67504.9266768149" constant="true"/>
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      <parameter id="n9" value="5.88499980572144" constant="true"/>
      <parameter id="g11" value="59994.4134510773" constant="true"/>
      <parameter id="m14" value="0.440879974257324" constant="true"/>
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      <parameter id="m23" value="1.48057704025775" constant="true"/>
      <parameter id="n10" value="5.01512745875978" constant="true"/>
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      <parameter id="dZG" value="29717.820753307" constant="true"/>
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      <parameter id="g2" value="595.533664539628" constant="true"/>
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      <parameter id="p26" value="6.03985788533193e-06" constant="true"/>
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      <parameter id="p6" value="0.6" constant="true"/>
      <parameter id="m27" value="0.1" constant="true"/>
      <parameter id="p15" value="3" constant="true"/>
      <parameter id="n6" value="20" constant="true"/>
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      <parameter id="m36" value="0.0988627559324387" constant="true"/>
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      <parameter id="q2" value="149.393841965426" constant="true"/>
      <parameter id="gmg" value="1" constant="true"/>
      <parameter id="n12" value="1047.3417892582" constant="true"/>
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      <parameter id="m18" value="4.17528060369758" constant="true"/>
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      <parameter id="m19" value="1.18499836603551" constant="true"/>
      <parameter id="p28" value="21.5197740727555" constant="true"/>
      <parameter id="p29" value="0.305804164480483" constant="true"/>
      <parameter id="m10" value="4.16475304417486" constant="true"/>
      <parameter id="cEG" value="0.00381490790681182" constant="true"/>
      <parameter id="m4" value="0.2" constant="true"/>
    </listOfParameters>
    <listOfInitialAssignments>
      <initialAssignment symbol="cL_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 1.05129004396331 </cn>
            <cn> 240.398303596736 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cP9_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.0656063461084473 </cn>
            <cn> 69.5228161344057 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cP7_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.429686087062748 </cn>
            <cn> 36.7151462664629 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cP5_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.778001394975754 </cn>
            <cn> 10.8150058554228 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cT_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.0928798167556545 </cn>
            <cn> 98.7139376747197 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cE4_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.0949886368399 </cn>
            <cn> 59.100196230293 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cE3_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.282857048667234 </cn>
            <cn> 37.4270777712061 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cLUX_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.0949886368399 </cn>
            <cn> 59.100196230293 </cn>
          </apply>
        </math>
      </initialAssignment>
      <initialAssignment symbol="cG_m">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <cn> 0.096830093091897 </cn>
            <cn> 71.2315112597985 </cn>
          </apply>
        </math>
      </initialAssignment>
    </listOfInitialAssignments>
    <listOfRules>
      <assignmentRule variable="cGn_tot">
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <plus/>
            <ci> cGn </ci>
            <ci> cEGn </ci>
          </apply>
        </math>
      </assignmentRule>
    </listOfRules>
    <listOfReactions>
      <reaction id="cL_m_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cL_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cP"/>
          <modifierSpeciesReference species="cP7"/>
          <modifierSpeciesReference species="cT"/>
          <modifierSpeciesReference species="cP9"/>
          <modifierSpeciesReference species="cP5"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <ci> q1 </ci>
                    <ci> L </ci>
                    <ci> cP </ci>
                    <ci> gml </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> n1 </ci>
                        <apply>
                          <power/>
                          <ci> gp7 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                        <apply>
                          <power/>
                          <ci> g1 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> gp7 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g1 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <apply>
                            <plus/>
                            <ci> cP9 </ci>
                            <ci> cP7 </ci>
                            <ci> cP5 </ci>
                            <ci> cT </ci>
                          </apply>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gml </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <apply>
                      <times/>
                      <ci> m1 </ci>
                      <ci> L </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m2 </ci>
                      <apply>
                        <minus/>
                        <cn type="integer"> 1 </cn>
                        <ci> L </ci>
                      </apply>
                    </apply>
                  </apply>
                  <ci> cL_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cL_m_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cL" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> p2 </ci>
                          <apply>
                            <times/>
                            <ci> p1 </ci>
                            <ci> L </ci>
                          </apply>
                        </apply>
                        <ci> cL_m </ci>
                      </apply>
                      <ci> gml </ci>
                    </apply>
                    <ci> gl </ci>
                  </apply>
                  <apply>
                    <times/>
                    <ci> m3 </ci>
                    <ci> cL </ci>
                  </apply>
                </apply>
                <apply>
                  <divide/>
                  <apply>
                    <times/>
                    <ci> p3 </ci>
                    <ci> gl </ci>
                    <apply>
                      <power/>
                      <ci> cL </ci>
                      <cn type="integer"> 2 </cn>
                    </apply>
                  </apply>
                  <apply>
                    <plus/>
                    <apply>
                      <power/>
                      <ci> cL </ci>
                      <cn type="integer"> 2 </cn>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <power/>
                        <ci> gl </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                      <apply>
                        <power/>
                        <ci> g3 </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cL_mod_pro" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cLmod" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <apply>
                    <times/>
                    <ci> p3 </ci>
                    <ci> gl </ci>
                    <apply>
                      <power/>
                      <ci> cL </ci>
                      <cn type="integer"> 2 </cn>
                    </apply>
                  </apply>
                  <apply>
                    <plus/>
                    <apply>
                      <power/>
                      <ci> cL </ci>
                      <cn type="integer"> 2 </cn>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <power/>
                        <ci> gl </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                      <apply>
                        <power/>
                        <ci> g3 </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m3 </ci>
                  <ci> cLmod </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP_prod" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <ci> p7 </ci>
                  <apply>
                    <minus/>
                    <cn type="integer"> 1 </cn>
                    <ci> L </ci>
                  </apply>
                  <apply>
                    <minus/>
                    <cn type="integer"> 1 </cn>
                    <ci> cP </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m11 </ci>
                  <ci> cP </ci>
                  <ci> L </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP9_m_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP9_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
          <modifierSpeciesReference species="cP"/>
          <modifierSpeciesReference species="cEC"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <ci> L </ci>
                    <ci> q3 </ci>
                    <ci> cP </ci>
                    <ci> gm9 </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> ge3 </ci>
                        <ci> g8 </ci>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <ci> ge3 </ci>
                          <ci> g8 </ci>
                        </apply>
                        <ci> cEC </ci>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> n4 </ci>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> n7 </ci>
                          <apply>
                            <power/>
                            <ci> cL </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <plus/>
                          <apply>
                            <power/>
                            <ci> cL </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <times/>
                            <apply>
                              <power/>
                              <ci> gl </ci>
                              <cn type="integer"> 2 </cn>
                            </apply>
                            <apply>
                              <power/>
                              <ci> g9 </ci>
                              <cn type="integer"> 2 </cn>
                            </apply>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gm9 </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m12 </ci>
                  <ci> cP9_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP9_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP9" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cP9_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <apply>
                    <times/>
                    <ci> gp7 </ci>
                    <ci> p8 </ci>
                    <ci> cP9_m </ci>
                  </apply>
                  <ci> gm9 </ci>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <ci> m13 </ci>
                    <apply>
                      <times/>
                      <ci> m22 </ci>
                      <apply>
                        <minus/>
                        <cn type="integer"> 1 </cn>
                        <ci> L </ci>
                      </apply>
                    </apply>
                  </apply>
                  <ci> cP9 </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP7_m_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP7_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
          <modifierSpeciesReference species="cLmod"/>
          <modifierSpeciesReference species="cP9"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> n8 </ci>
                        <apply>
                          <power/>
                          <apply>
                            <plus/>
                            <ci> cL </ci>
                            <ci> cLmod </ci>
                          </apply>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> gl </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g10 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <apply>
                            <plus/>
                            <ci> cL </ci>
                            <ci> cLmod </ci>
                          </apply>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gm7 </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> n9 </ci>
                        <apply>
                          <power/>
                          <ci> cP9 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> gp7 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g11 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <ci> cP9 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gm7 </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m14 </ci>
                  <ci> cP7_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP7_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP7" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cP7_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <apply>
                    <times/>
                    <ci> gp7 </ci>
                    <ci> p9 </ci>
                    <ci> cP7_m </ci>
                  </apply>
                  <ci> gm7 </ci>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <ci> m15 </ci>
                    <apply>
                      <times/>
                      <ci> m23 </ci>
                      <apply>
                        <minus/>
                        <cn type="integer"> 1 </cn>
                        <ci> L </ci>
                      </apply>
                    </apply>
                  </apply>
                  <ci> cP7 </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP5_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP5_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cP7"/>
          <modifierSpeciesReference species="cLmod"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> n10 </ci>
                        <apply>
                          <power/>
                          <ci> cLmod </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> gl </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g12 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <ci> cLmod </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gm5 </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> n11 </ci>
                        <apply>
                          <power/>
                          <ci> cP7 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> gp7 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g13 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <ci> cP7 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gm5 </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m16 </ci>
                  <ci> cP5_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cP5_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cP5" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cP5_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <apply>
                    <times/>
                    <ci> gp7 </ci>
                    <ci> p10 </ci>
                    <ci> cP5_m </ci>
                  </apply>
                  <ci> gm5 </ci>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <ci> m17 </ci>
                    <apply>
                      <times/>
                      <ci> m24 </ci>
                      <apply>
                        <minus/>
                        <cn type="integer"> 1 </cn>
                        <ci> L </ci>
                      </apply>
                    </apply>
                  </apply>
                  <ci> cP5 </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cT_m_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cT_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
          <modifierSpeciesReference species="cEC"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> n2 </ci>
                          <ci> ge3 </ci>
                          <ci> g4 </ci>
                        </apply>
                        <apply>
                          <plus/>
                          <apply>
                            <times/>
                            <ci> ge3 </ci>
                            <ci> g4 </ci>
                          </apply>
                          <ci> cEC </ci>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> gl </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                      <apply>
                        <power/>
                        <ci> g5 </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <power/>
                          <ci> gl </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                        <apply>
                          <power/>
                          <ci> g5 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> cL </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                  </apply>
                  <ci> gmt </ci>
                </apply>
                <apply>
                  <times/>
                  <ci> m5 </ci>
                  <ci> cT_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cT_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cT" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cZTL"/>
          <modifierSpeciesReference species="cZG"/>
          <modifierSpeciesReference species="cT_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> gp7 </ci>
                      <ci> p4 </ci>
                      <ci> cT_m </ci>
                    </apply>
                    <ci> gmt </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <plus/>
                      <ci> m6 </ci>
                      <apply>
                        <times/>
                        <ci> m7 </ci>
                        <apply>
                          <minus/>
                          <cn type="integer"> 1 </cn>
                          <ci> L </ci>
                        </apply>
                      </apply>
                    </apply>
                    <ci> cT </ci>
                    <apply>
                      <plus/>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> cZTL </ci>
                          <ci> p5 </ci>
                        </apply>
                        <ci> ge3 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <ci> cZG </ci>
                        <apply>
                          <times/>
                          <ci> dZG </ci>
                          <ci> ge3 </ci>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m8 </ci>
                  <ci> cT </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cE4_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cE4_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
          <modifierSpeciesReference species="cEC"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> n13 </ci>
                          <ci> ge3 </ci>
                          <ci> g2 </ci>
                        </apply>
                        <apply>
                          <plus/>
                          <apply>
                            <times/>
                            <ci> ge3 </ci>
                            <ci> g2 </ci>
                          </apply>
                          <ci> cEC </ci>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> gl </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                      <apply>
                        <power/>
                        <ci> g6 </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <power/>
                          <ci> gl </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                        <apply>
                          <power/>
                          <ci> g6 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> cL </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                  </apply>
                  <ci> gm4 </ci>
                </apply>
                <apply>
                  <times/>
                  <ci> m34 </ci>
                  <ci> cE4_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cE4_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cE4" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cE4_m"/>
          <modifierSpeciesReference species="cE34"/>
          <modifierSpeciesReference species="cE3n"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <plus/>
                <apply>
                  <minus/>
                  <apply>
                    <minus/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> p23 </ci>
                        <ci> ge3 </ci>
                        <ci> cE4_m </ci>
                      </apply>
                      <ci> gm4 </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m35 </ci>
                      <ci> cE4 </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <ci> p25 </ci>
                      <ci> ge3 </ci>
                    </apply>
                    <ci> cE4 </ci>
                    <ci> cE3n </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> p21 </ci>
                  <ci> cE34 </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cE3_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cE3_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> n3 </ci>
                      <apply>
                        <power/>
                        <ci> gl </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                      <apply>
                        <power/>
                        <ci> g16 </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <power/>
                          <ci> gl </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                        <apply>
                          <power/>
                          <ci> g16 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> cL </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                  </apply>
                  <ci> gm3 </ci>
                </apply>
                <apply>
                  <times/>
                  <ci> m26 </ci>
                  <ci> cE3_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cE3c_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cE3c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cE3_m"/>
          <modifierSpeciesReference species="cGc"/>
          <modifierSpeciesReference species="cCOP1c"/>
          <modifierSpeciesReference species="cE3n"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <plus/>
                <apply>
                  <minus/>
                  <apply>
                    <minus/>
                    <apply>
                      <minus/>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> p16 </ci>
                          <ci> ge3 </ci>
                          <ci> cE3_m </ci>
                        </apply>
                        <ci> gm3 </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> m9 </ci>
                        <ci> cE3c </ci>
                        <ci> cCOP1c </ci>
                      </apply>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p17 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> cE3c </ci>
                      <ci> cGc </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> p19 </ci>
                    <ci> cE3c </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> p20 </ci>
                  <ci> cE3n </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cE3n_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cE3n" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cGn"/>
          <modifierSpeciesReference species="cCOP1n"/>
          <modifierSpeciesReference species="cCOP1d"/>
          <modifierSpeciesReference species="cE3c"/>
          <modifierSpeciesReference species="cE4"/>
          <modifierSpeciesReference species="cE34"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <minus/>
                    <apply>
                      <minus/>
                      <apply>
                        <minus/>
                        <apply>
                          <minus/>
                          <apply>
                            <times/>
                            <ci> p19 </ci>
                            <ci> cE3c </ci>
                          </apply>
                          <apply>
                            <times/>
                            <ci> p20 </ci>
                            <ci> cE3n </ci>
                          </apply>
                        </apply>
                        <apply>
                          <times/>
                          <apply>
                            <divide/>
                            <ci> p17 </ci>
                            <ci> ge3 </ci>
                          </apply>
                          <ci> cE3n </ci>
                          <ci> cGn </ci>
                        </apply>
                      </apply>
                      <apply>
                        <times/>
                        <ci> m30 </ci>
                        <ci> cE3n </ci>
                        <ci> cCOP1d </ci>
                      </apply>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m29 </ci>
                      <ci> cE3n </ci>
                      <ci> cCOP1n </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> p21 </ci>
                    <ci> cE34 </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <ci> p25 </ci>
                    <ci> ge3 </ci>
                  </apply>
                  <ci> cE4 </ci>
                  <ci> cE3n </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cLUX_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cLUX_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
          <modifierSpeciesReference species="cEC"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> n13 </ci>
                          <ci> ge3 </ci>
                          <ci> g2 </ci>
                        </apply>
                        <apply>
                          <plus/>
                          <apply>
                            <times/>
                            <ci> ge3 </ci>
                            <ci> g2 </ci>
                          </apply>
                          <ci> cEC </ci>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> gl </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                      <apply>
                        <power/>
                        <ci> g6 </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <power/>
                          <ci> gl </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                        <apply>
                          <power/>
                          <ci> g6 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <power/>
                        <ci> cL </ci>
                        <cn type="integer"> 2 </cn>
                      </apply>
                    </apply>
                  </apply>
                  <ci> gm4 </ci>
                </apply>
                <apply>
                  <times/>
                  <ci> m34 </ci>
                  <ci> cLUX_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cLUX_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cLUX" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cE34"/>
          <modifierSpeciesReference species="cLUX_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> p27 </ci>
                      <ci> ge3 </ci>
                      <ci> cLUX_m </ci>
                    </apply>
                    <ci> gm4 </ci>
                  </apply>
                  <apply>
                    <times/>
                    <ci> m39 </ci>
                    <ci> cLUX </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <ci> p26 </ci>
                    <ci> ge3 </ci>
                  </apply>
                  <ci> cLUX </ci>
                  <ci> cE34 </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cCOP1c_prod" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cCOP1c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <ci> n5 </ci>
                  <apply>
                    <times/>
                    <ci> p6 </ci>
                    <ci> cCOP1c </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m27 </ci>
                  <ci> cCOP1c </ci>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <times/>
                      <ci> p15 </ci>
                      <ci> L </ci>
                    </apply>
                  </apply>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cCOP1n_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cCOP1n" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cP"/>
          <modifierSpeciesReference species="cCOP1c"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <apply>
                    <minus/>
                    <apply>
                      <times/>
                      <ci> p6 </ci>
                      <ci> cCOP1c </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> n6 </ci>
                      <ci> L </ci>
                      <ci> cP </ci>
                      <ci> cCOP1n </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> n14 </ci>
                    <ci> cCOP1n </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m27 </ci>
                  <ci> cCOP1n </ci>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <times/>
                      <ci> p15 </ci>
                      <ci> L </ci>
                    </apply>
                  </apply>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cCOP1d_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cCOP1d" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cCOP1n"/>
          <modifierSpeciesReference species="cP"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <ci> n14 </ci>
                    <ci> cCOP1n </ci>
                  </apply>
                  <apply>
                    <times/>
                    <ci> n6 </ci>
                    <ci> L </ci>
                    <ci> cP </ci>
                    <ci> cCOP1n </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m31 </ci>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <times/>
                      <ci> m33 </ci>
                      <apply>
                        <minus/>
                        <cn type="integer"> 1 </cn>
                        <ci> L </ci>
                      </apply>
                    </apply>
                  </apply>
                  <ci> cCOP1d </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cEGc_prod" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cEGc" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cEGn"/>
          <modifierSpeciesReference species="cE3c"/>
          <modifierSpeciesReference species="cGc"/>
          <modifierSpeciesReference species="cCOP1c"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <plus/>
                <apply>
                  <minus/>
                  <apply>
                    <minus/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p17 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> cE3c </ci>
                      <ci> cGc </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m9 </ci>
                      <ci> cEGc </ci>
                      <ci> cCOP1c </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> p18 </ci>
                    <ci> cEGc </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> p31 </ci>
                  <ci> cEGn </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cEC_form" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cEC" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cCOP1n"/>
          <modifierSpeciesReference species="cCOP1d"/>
          <modifierSpeciesReference species="cE34"/>
          <modifierSpeciesReference species="cLUX"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <apply>
                    <minus/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p26 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> cLUX </ci>
                      <ci> cE34 </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m36 </ci>
                      <ci> cEC </ci>
                      <ci> cCOP1n </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> m37 </ci>
                    <ci> cEC </ci>
                    <ci> cCOP1d </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m32 </ci>
                  <ci> cEC </ci>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> p24 </ci>
                        <ci> L </ci>
                        <apply>
                          <power/>
                          <ci> cGn_tot </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> ge3 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g7 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <ci> cGn_tot </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cZTL_prod" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cZTL" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cZG"/>
          <modifierSpeciesReference species="cGc"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <minus/>
                    <apply>
                      <times/>
                      <ci> ge3 </ci>
                      <ci> p14 </ci>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p12 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> L </ci>
                      <ci> cZTL </ci>
                      <ci> cGc </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> p13 </ci>
                    <ci> cZG </ci>
                    <apply>
                      <minus/>
                      <cn type="integer"> 1 </cn>
                      <ci> L </ci>
                    </apply>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m20 </ci>
                  <ci> cZTL </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cZG_prod" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cZG" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cZTL"/>
          <modifierSpeciesReference species="cGc"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <minus/>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <ci> p12 </ci>
                      <ci> ge3 </ci>
                    </apply>
                    <ci> L </ci>
                    <ci> cZTL </ci>
                    <ci> cGc </ci>
                  </apply>
                  <apply>
                    <times/>
                    <ci> p13 </ci>
                    <ci> cZG </ci>
                    <apply>
                      <minus/>
                      <cn type="integer"> 1 </cn>
                      <ci> L </ci>
                    </apply>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m21 </ci>
                  <ci> cZG </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cG_m_trscr" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cG_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cL"/>
          <modifierSpeciesReference species="cP"/>
          <modifierSpeciesReference species="cEC"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <ci> L </ci>
                    <ci> q2 </ci>
                    <ci> cP </ci>
                    <ci> gmg </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> n12 </ci>
                            <ci> ge3 </ci>
                            <ci> g14 </ci>
                          </apply>
                          <apply>
                            <plus/>
                            <apply>
                              <times/>
                              <ci> ge3 </ci>
                              <ci> g14 </ci>
                            </apply>
                            <ci> cEC </ci>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <ci> gl </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                        <apply>
                          <power/>
                          <ci> g15 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <power/>
                            <ci> gl </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                          <apply>
                            <power/>
                            <ci> g15 </ci>
                            <cn type="integer"> 2 </cn>
                          </apply>
                        </apply>
                        <apply>
                          <power/>
                          <ci> cL </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                    <ci> gmg </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> m18 </ci>
                  <ci> cG_m </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cG_trans" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cGc" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cZTL"/>
          <modifierSpeciesReference species="cZG"/>
          <modifierSpeciesReference species="cGn"/>
          <modifierSpeciesReference species="cE3c"/>
          <modifierSpeciesReference species="cG_m"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <plus/>
                <apply>
                  <minus/>
                  <apply>
                    <minus/>
                    <apply>
                      <minus/>
                      <apply>
                        <plus/>
                        <apply>
                          <minus/>
                          <apply>
                            <divide/>
                            <apply>
                              <times/>
                              <ci> p11 </ci>
                              <ci> ge3 </ci>
                              <ci> cG_m </ci>
                            </apply>
                            <ci> gmg </ci>
                          </apply>
                          <apply>
                            <times/>
                            <apply>
                              <divide/>
                              <ci> p12 </ci>
                              <ci> ge3 </ci>
                            </apply>
                            <ci> L </ci>
                            <ci> cZTL </ci>
                            <ci> cGc </ci>
                          </apply>
                        </apply>
                        <apply>
                          <times/>
                          <ci> p13 </ci>
                          <ci> cZG </ci>
                          <apply>
                            <minus/>
                            <cn type="integer"> 1 </cn>
                            <ci> L </ci>
                          </apply>
                        </apply>
                      </apply>
                      <apply>
                        <times/>
                        <ci> m19 </ci>
                        <ci> cGc </ci>
                      </apply>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p17 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> cE3c </ci>
                      <ci> cGc </ci>
                    </apply>
                  </apply>
                  <apply>
                    <times/>
                    <ci> p28 </ci>
                    <ci> cGc </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <ci> p29 </ci>
                  <ci> cGn </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cGn_traspo" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cGn" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cGc"/>
          <modifierSpeciesReference species="cE3n"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <ci> p28 </ci>
                  <ci> cGc </ci>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <ci> p29 </ci>
                    <ci> m19 </ci>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p17 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> cE3n </ci>
                    </apply>
                  </apply>
                  <ci> cGn </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cE34_compl" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cE34" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cCOP1n"/>
          <modifierSpeciesReference species="cCOP1d"/>
          <modifierSpeciesReference species="cE4"/>
          <modifierSpeciesReference species="cLUX"/>
          <modifierSpeciesReference species="cE3n"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <times/>
                  <apply>
                    <divide/>
                    <ci> p25 </ci>
                    <ci> ge3 </ci>
                  </apply>
                  <ci> cE4 </ci>
                  <ci> cE3n </ci>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> p26 </ci>
                        <ci> ge3 </ci>
                      </apply>
                      <ci> cLUX </ci>
                    </apply>
                    <ci> p21 </ci>
                    <apply>
                      <times/>
                      <ci> m37 </ci>
                      <ci> cCOP1d </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m36 </ci>
                      <ci> cCOP1n </ci>
                    </apply>
                  </apply>
                  <ci> cE34 </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="cEGn_tranp" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cEGn" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="cGn"/>
          <modifierSpeciesReference species="cCOP1n"/>
          <modifierSpeciesReference species="cCOP1d"/>
          <modifierSpeciesReference species="cE3n"/>
          <modifierSpeciesReference species="cEGc"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> cell </ci>
              <apply>
                <minus/>
                <apply>
                  <plus/>
                  <apply>
                    <times/>
                    <ci> p18 </ci>
                    <ci> cEGc </ci>
                  </apply>
                  <apply>
                    <times/>
                    <apply>
                      <divide/>
                      <ci> p17 </ci>
                      <ci> ge3 </ci>
                    </apply>
                    <ci> cE3n </ci>
                    <ci> cGn </ci>
                  </apply>
                </apply>
                <apply>
                  <times/>
                  <apply>
                    <plus/>
                    <apply>
                      <times/>
                      <ci> m9 </ci>
                      <ci> cCOP1n </ci>
                    </apply>
                    <apply>
                      <times/>
                      <ci> m10 </ci>
                      <ci> cCOP1d </ci>
                    </apply>
                    <ci> p31 </ci>
                  </apply>
                  <ci> cEGn </ci>
                </apply>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
    </listOfReactions>
    <listOfEvents>
      <event id="_E0" useValuesFromTriggerTime="true">
        <trigger initialValue="true" persistent="true">
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <and/>
              <apply>
                <geq/>
                <piecewise>
                  <piece>
                    <apply>
                      <minus/>
                      <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                      <apply>
                        <times/>
                        <cn type="integer"> 24 </cn>
                        <apply>
                          <ceiling/>
                          <apply>
                            <divide/>
                            <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                            <cn type="integer"> 24 </cn>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <xor/>
                      <apply>
                        <lt/>
                        <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                        <cn type="integer"> 0 </cn>
                      </apply>
                      <apply>
                        <lt/>
                        <cn type="integer"> 24 </cn>
                        <cn type="integer"> 0 </cn>
                      </apply>
                    </apply>
                  </piece>
                  <otherwise>
                    <apply>
                      <minus/>
                      <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                      <apply>
                        <times/>
                        <cn type="integer"> 24 </cn>
                        <apply>
                          <floor/>
                          <apply>
                            <divide/>
                            <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                            <cn type="integer"> 24 </cn>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </otherwise>
                </piecewise>
                <cn type="integer"> 12 </cn>
              </apply>
              <apply>
                <lt/>
                <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                <apply>
                  <times/>
                  <cn type="integer"> 24 </cn>
                  <cn type="integer"> 11 </cn>
                </apply>
              </apply>
            </apply>
          </math>
        </trigger>
        <listOfEventAssignments>
          <eventAssignment variable="L">
            <math xmlns="http://www.w3.org/1998/Math/MathML">
              <cn type="integer"> 0 </cn>
            </math>
          </eventAssignment>
        </listOfEventAssignments>
      </event>
      <event id="_E1" useValuesFromTriggerTime="true">
        <trigger initialValue="true" persistent="true">
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <and/>
              <apply>
                <lt/>
                <piecewise>
                  <piece>
                    <apply>
                      <minus/>
                      <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                      <apply>
                        <times/>
                        <cn type="integer"> 24 </cn>
                        <apply>
                          <ceiling/>
                          <apply>
                            <divide/>
                            <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                            <cn type="integer"> 24 </cn>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <xor/>
                      <apply>
                        <lt/>
                        <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                        <cn type="integer"> 0 </cn>
                      </apply>
                      <apply>
                        <lt/>
                        <cn type="integer"> 24 </cn>
                        <cn type="integer"> 0 </cn>
                      </apply>
                    </apply>
                  </piece>
                  <otherwise>
                    <apply>
                      <minus/>
                      <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                      <apply>
                        <times/>
                        <cn type="integer"> 24 </cn>
                        <apply>
                          <floor/>
                          <apply>
                            <divide/>
                            <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                            <cn type="integer"> 24 </cn>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </otherwise>
                </piecewise>
                <cn type="integer"> 12 </cn>
              </apply>
              <apply>
                <lt/>
                <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
                <apply>
                  <times/>
                  <cn type="integer"> 24 </cn>
                  <cn type="integer"> 11 </cn>
                </apply>
              </apply>
            </apply>
          </math>
        </trigger>
        <listOfEventAssignments>
          <eventAssignment variable="L">
            <math xmlns="http://www.w3.org/1998/Math/MathML">
              <cn type="integer"> 1 </cn>
            </math>
          </eventAssignment>
        </listOfEventAssignments>
      </event>
      <event id="_E2" useValuesFromTriggerTime="true">
        <trigger initialValue="true" persistent="true">
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <geq/>
              <csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
              <apply>
                <times/>
                <cn type="integer"> 24 </cn>
                <cn type="integer"> 11 </cn>
              </apply>
            </apply>
          </math>
        </trigger>
        <listOfEventAssignments>
          <eventAssignment variable="L">
            <math xmlns="http://www.w3.org/1998/Math/MathML">
              <cn type="integer"> 1 </cn>
            </math>
          </eventAssignment>
        </listOfEventAssignments>
      </event>
    </listOfEvents>
  </model>
</sbml>