As used in A.P. Kupinski, I. Raabe, M. Michel, D. Ail, L. Brusch, T. Weidemann, C. Bökel (2013) Phosphorylation of the Smo tail is controlled by membrane localization and is dispensable for clustering, J. Cell Sci., 126, 20, 4684-4697 doi: 10.1242/​jcs.128926

- 1 * (PM_k1 * PMSmo - PM_k2 * PMSmoP) - 1 * ((k0 + k1_2 * Ptc) * PMSmo - Smo_k2 * EESmo) 1 * (PM_k1 * PMSmo - PM_k2 * PMSmoP) - 1 * ((SmoP_k0 + k1_3 * Ptc) * PMSmoP - k2_3 * EESmoP) - 1 * (k1 * EESmo - k2 * EESmoP) + 1 * ((k0 + k1_2 * Ptc) * PMSmo - Smo_k2 * EESmo) 1 * (k1 * EESmo - k2 * EESmoP) + 1 * ((SmoP_k0 + k1_3 * Ptc) * PMSmoP - k2_3 * EESmoP) 1 * (k - Hh * Ptc) EESmoP + EESmo + PMSmoP + PMSmo Smototal / (1 + PM_k2 / PM_k1 + (SmoP_k0 + PM_k2 / PM_k1 / Hh) / Smo_k2)