Table S4. Overview of patient characteristics
Patient characteristics pertaining to fibroblasts used for modle personalisation.
SEEK ID: https://fairdomhub.org/documents/4158?version=4
Filename: Table S4. Overview of patient characteristics.xlsx
Format: Spreadsheet
Size: 11.6 KB
Export PNG
Download
Creators and SubmitterCreators
Additional credit
Anne-Claire Martines; Karin Wolters
Submitter
Views: 83 Downloads: 3
Created: 7th Mar 2023 at 14:50
Last updated: 9th Jun 2023 at 14:55
TagsThis item has not yet been tagged.
AttributionsNone
Version History
Version 4 (latest) Created 9th Jun 2023 at 14:55 by Christoff Odendaal
No revision comments
Version 3 Created 9th Jun 2023 at 14:03 by Christoff Odendaal
No revision comments
Version 2 Created 7th Jun 2023 at 16:44 by Christoff Odendaal
No revision comments
Version 1 (earliest) Created 7th Mar 2023 at 14:50 by Christoff Odendaal
No revision comments
Related items
https://orcid.org/0000-0001-6274-3633I am a Professor in Medical Systems Biology and the University Medical Centre Groningen. The research in my lab is focused on complex regulation of mammalian lipid and carbohydrate metabolism, eventually aiming at network-based therapies. We combine dynamic computer simulations with quantitative metabolomics, 13C fluxomics, proteomics and transcriptome analysis, and in depth biochemical analysis. This allows to predict and understand ‘emergent’ properties, those properties that are counterintuitive ...
Projects: PoLiMeR - Polymers in the Liver: Metabolism and Regulation
Institutions: University of Leiden
Projects: PoLiMeR - Polymers in the Liver: Metabolism and Regulation
Institutions: University Medical Centre Groningen
PoLiMeR is funded through the EU Marie Skłodowska-Curie Innovative Training Network (ITN), which drives scientific excellence and innovation. ITNs bring together universities, research institutes, industry and clinical partners from across the world to train researchers to doctorate level.
Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease ...
Programme: This Project is not associated with a Programme
Public web page: http://polimer-itn.eu/
Creation of personalised models of control, symptomatic MCADD, asymptomatic MCADD, and early diagnosis MCADD individuals using fibroblast proteomics to adjust model Vmaxes. Generates Fig. 7 and S7.
Download and unzip "Model_notebooks.rar" and run "13, Fig7-personalised-models-[needs-(1-and-12)]-20221109.nb" after running "1, generate-model-20221109.nb" and "12, Fig7-S7-preprocessing-[needs-(1)-]-20221109.nb".
Submitter: Christoff Odendaal
Biological problem addressed: Model Analysis Type
Investigation: Mitochondrial fatty acid oxidation in human liver
Study: Model analysis
