In [2]:
options(warn = -1)

suppressPackageStartupMessages({
library(minfi)
library(ggplot2)
library(tidyverse)
library(openxlsx)
library(ggrepel)
library(patchwork)
library(gridExtra) 
library(scatterplot3d)
library(corrplot)
library(dplyr)
library(IlluminaHumanMethylationEPICanno.ilm10b4.hg19)
library(tibble)
library(clusterProfiler)
library(org.Hs.eg.db)
library(tidyverse)
library(data.table)
library(pheatmap)
library(biomaRt)
})
In [3]:
setwd("/nfs_data/aismail_work/20250610_iwohlers_dnamethyl_alliance_weckmann/ERA DNAm and RNA/meqtl")
In [3]:
list.files()
  1. 'cis_eqtl_hits.tsv'
  2. 'cis_eQTL_IRN_hits.tsv'
  3. 'cis_mQTL_all_hits.tsv'
  4. 'cis_mQTL_hits.tsv'
  5. 'cis_mQTL_IRN_hits.tsv'
  6. 'cov_mat.tsv'
  7. 'expr.tsv'
  8. 'expression_IRN.tsv'
  9. 'expression_IRN.txt'
  10. 'genepos.tsv'
  11. 'geni_M.tsv'
  12. 'geno.tsv'
  13. 'mqtl_assoc.txt'
  14. 'mqtl_clumped.log'
In [29]:
read_df <- function(path) {
  read.delim(path, header = TRUE, row.names = 1, check.names = FALSE)
}


# Load all files
expr     <- read_df("expr.tsv")
cov      <- read_df("cov_mat.tsv")
genopos  <- read_df("genepos.tsv")
geno     <- read_df("geno.tsv")
snpspos  <- read_df("/nfs_data/aismail_work/20250610_iwohlers_dnamethyl_alliance_weckmann/ERA DNAm and RNA/snpspos.tsv")
In [5]:
head(expr)
dim(expr)
head(cov)
dim(cov)
head(genopos)
dim(genopos)
head(geno)
dim(geno)
head(snpspos)
dim(snpspos)
A data.frame: 6 × 139
ID0022ID0251ID0262ID0393ID0439ID0479ID0494ID0511ID0805ID0824⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>⋯<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>
A_33_P3396872_CPED1-1.3689394 3.35107900-1.5051055-0.39192100.3850131 2.5947420 0.03072715-1.4636159 0.3961468-1.2659259⋯ 0.630114100 0.40203762-1.0073109-0.04738903-0.084532260.7277513 0.7365842 1.5147915-0.48138620.9984970
A_33_P3267760_BCOR 0.3959370 2.06494450-0.3671009-1.20937301.0980093 2.3443660-0.12487650-1.0065427 0.5497692-0.8935125⋯ 0.077516080-0.41262817-1.8239913-0.86885524-0.907292370.3081295 1.0509560 0.9189892 0.11459850.1810920
A_32_P194264_CHAC2-0.1801887-0.01972044-0.5567336 0.33784960.8185678-0.0987730-0.44758940-0.3977628 0.3122244-0.3372707⋯-0.003941298 0.38526940-0.5616155 0.17150330 0.466360100.5097628-0.3861752-0.7476590 0.36443660.3454075
A_23_P153745_IFI30-0.1421785 0.20207262 0.9367528 1.73634241.0529761-0.3199029-0.03545046 1.0249705 0.5785976-0.7004619⋯ 1.114379400-0.09802437 1.4124017-0.04797649 0.655091760.5061412-0.2821751-0.2783618 1.12284900.6665168
A_21_P0014180_GPR146-0.7417617 2.71373770-0.8150744-0.97163770.8826017 3.3624630-0.26760864-0.3405328 0.2833872-1.5254574⋯ 0.044141054 1.34398890-1.5810790-0.64827347-0.695132500.1501574 0.5867124-0.1551046-0.81556850.4210672
A_24_P944991_SREK1IP1-1.0763819 0.27145565-0.3387217 0.40003230.8925309 1.3142984-0.80259420-0.8872940-1.2592742-2.9163077⋯-1.033968700 0.95221496 0.1884344-0.32434702-0.262824770.6718693 0.2276502-0.2446258 0.18077540.7313895
  1. 29851
  2. 139
A data.frame: 2 × 139
ID0022ID0251ID0262ID0393ID0439ID0479ID0494ID0511ID0805ID0824⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<int><int><int><int><int><int><int><int><int><int>⋯<int><int><int><int><int><int><int><int><int><int>
age68556769273928474965⋯70215467606649765345
sex 1 1 1 0 0 1 1 1 1 1⋯ 1 1 1 0 0 0 0 0 1 0
  1. 2
  2. 139
A data.frame: 6 × 3
ChromosomeStartEnd
<chr><int><int>
A_33_P3396872_CPED17 120628731120937498
A_33_P3267760_BCORX 39909068 40036582
A_32_P194264_CHAC22 53994929 54002333
A_23_P153745_IFI3019 18283972 18288927
A_21_P0014180_GPR1467 1084212 1098897
A_24_P944991_SREK1IP15 64013971 64064512
  1. 29851
  2. 3
A data.frame: 6 × 139
ID0022ID0251ID0262ID0393ID0439ID0479ID0494ID0511ID0805ID0824⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<int><int><int><int><int><int><int><int><int><int>⋯<int><int><int><int><int><int><int><int><int><int>
rs5752721510000000001⋯0000010011
rs5444190190000000001⋯0000010011
rs626352860000101000⋯0100000010
rs2005799490000101000⋯0100000010
rs5317308561010000000⋯1000001000
rs5461694440000000011⋯0001000001
  1. 5967986
  2. 139
A data.frame: 6 × 2
ChromosomePosition
<int><int>
rs575272151111008
rs544419019111012
rs62635286113116
rs200579949113118
rs531730856113273
rs546169444114464
  1. 5967986
  2. 2

MQTL

In [30]:
load('/nfs_data/aismail_work/20250610_iwohlers_dnamethyl_alliance_weckmann/ERA DNAm and RNA/250610 ERA dasen DNA methlation.RData')
In [31]:
ls()
  1. 'cov'
  2. 'ERA_phenodata.filtered'
  3. 'ERA.beta.dasen'
  4. 'ERA.M.dasen'
  5. 'expr'
  6. 'fdr_threshold'
  7. 'fdr_y'
  8. 'geno'
  9. 'genopos'
  10. 'hits_pos'
  11. 'mqtl_hits'
  12. 'mqtl_manhattan'
  13. 'read_df'
  14. 'sig_mqtls'
  15. 'snpspos'
  16. 'top_hits'
In [32]:
head(ERA.beta.dasen)
A data.frame: 6 × 219
ID0051.t00ID5100.t00ID2828.t00ID7549.t00ID8478.t00ID5228.t00ID9318.t00ID1520.t00ID2847.t00ID9621.t00⋯ID3473.t00ID1542.t00ID9565.t00ID3545.t00ID9735.t00ID8754.t00ID0229.t00ID1388.t12ID6934.t12ID8931.t24
<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>⋯<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>
cg184781050.052463910.051413240.049818310.049122960.058043810.049152640.048318160.042812720.045803490.05362467⋯0.054817130.055317510.057173900.049928400.054121320.056027770.041745850.044040450.050316410.05245847
cg143616720.667866200.733333240.715529350.782500250.704248750.691572600.651755090.676930480.628792460.71071180⋯0.718997520.710370910.675272130.642528110.726936180.756486730.750160150.760132880.745656720.71552075
cg017636660.823185260.834570930.861326560.825507090.818356160.841787530.855310050.854370480.847614350.87229842⋯0.861016740.836394590.841946990.852776810.824864550.867781610.856171320.833448510.829621360.83395663
cg129503820.810362870.835689330.839708450.803072350.868158010.827669230.888611670.809674220.837555440.83384756⋯0.887577710.879653190.876108360.898723030.897543680.883884180.655361110.820244930.838203590.81655352
cg021153940.113237650.106884390.083799360.094426200.076237520.072067150.097126650.093726040.083403900.11567143⋯0.133857050.146993000.115358510.103040620.095862710.103522470.109822180.120443520.115815790.12423598
cg134174200.071554510.053524230.062017580.078511780.088464240.075732970.086332240.069737100.085846600.05953231⋯0.084781950.061992420.073713770.072737290.092396930.063155140.051619260.054792390.104986210.07736405
In [33]:
colnames(ERA.beta.dasen) <- gsub("\\.t.*", "",colnames(ERA.beta.dasen))
head(ERA.beta.dasen)
A data.frame: 6 × 219
ID0051ID5100ID2828ID7549ID8478ID5228ID9318ID1520ID2847ID9621⋯ID3473ID1542ID9565ID3545ID9735ID8754ID0229ID1388ID6934ID8931
<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>⋯<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>
cg184781050.052463910.051413240.049818310.049122960.058043810.049152640.048318160.042812720.045803490.05362467⋯0.054817130.055317510.057173900.049928400.054121320.056027770.041745850.044040450.050316410.05245847
cg143616720.667866200.733333240.715529350.782500250.704248750.691572600.651755090.676930480.628792460.71071180⋯0.718997520.710370910.675272130.642528110.726936180.756486730.750160150.760132880.745656720.71552075
cg017636660.823185260.834570930.861326560.825507090.818356160.841787530.855310050.854370480.847614350.87229842⋯0.861016740.836394590.841946990.852776810.824864550.867781610.856171320.833448510.829621360.83395663
cg129503820.810362870.835689330.839708450.803072350.868158010.827669230.888611670.809674220.837555440.83384756⋯0.887577710.879653190.876108360.898723030.897543680.883884180.655361110.820244930.838203590.81655352
cg021153940.113237650.106884390.083799360.094426200.076237520.072067150.097126650.093726040.083403900.11567143⋯0.133857050.146993000.115358510.103040620.095862710.103522470.109822180.120443520.115815790.12423598
cg134174200.071554510.053524230.062017580.078511780.088464240.075732970.086332240.069737100.085846600.05953231⋯0.084781950.061992420.073713770.072737290.092396930.063155140.051619260.054792390.104986210.07736405
In [34]:
com<- Reduce(intersect, list(colnames(geno), colnames(ERA.beta.dasen)))
meth  <- ERA.beta.dasen[, com, drop = FALSE]
head(meth)
dim(meth)
A data.frame: 6 × 130
ID0022ID0262ID0393ID0439ID0479ID0494ID0511ID0824ID0879ID1075⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>⋯<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>
cg184781050.044937370.066761490.05069250.058392700.046561210.050411940.051938090.046584070.050605910.06310769⋯0.045625120.056042840.056134250.050653790.053624670.054163640.055906490.053412710.051632740.06120382
cg143616720.721733590.759846160.69230650.715978440.742338130.723293600.715620720.679430870.745100080.71969152⋯0.726706730.737098090.705352130.745818810.710711800.718692740.741084820.734338090.740714820.72361315
cg017636660.850854610.827507910.82976220.853815590.797000730.817304330.806208850.843390060.854725440.81193033⋯0.859207450.839721260.833400570.846646520.872298420.845204400.868964510.854316790.835421130.84568474
cg129503820.834233980.930070210.82916150.904139600.854069830.819054000.831567670.848787160.852507700.85984169⋯0.821294880.872148150.916340150.868005390.833847560.874383360.868753120.859441780.915559110.81581543
cg021153940.071682390.108149580.15305760.100834330.127769260.100710090.079348270.105522870.111188010.10977465⋯0.090399460.075309700.089627270.110693870.115671430.078814270.089382070.057794520.102840750.10721822
cg134174200.060761400.075543130.14288110.057981940.065471890.102195980.092891600.051792870.091675240.09668951⋯0.064694730.068313970.077296470.074517280.059532310.077866670.078823500.100279220.074192880.06533796
  1. 786553
  2. 130
In [35]:
beta <- meth   

library(IlluminaHumanMethylationEPICanno.ilm10b4.hg19)
anno <- getAnnotation(IlluminaHumanMethylationEPICanno.ilm10b4.hg19)

# Keep only annotation entries that exist in beta
anno <- anno[rownames(anno) %in% rownames(beta), ]

#  ALIGN beta rows to annotation rows
beta <- beta[rownames(anno), ]

# Filter for autosomal chromosomes (chr1–chr22)
autosomal_idx <- anno$chr %in% paste0("chr", 1:22)

anno <- anno[autosomal_idx, ]     # <- filter annotation
beta <- beta[autosomal_idx, ]     # <- apply the same filter to beta

# 4. Build anno_df AFTER filtering so they match exactly
anno_df <- as.data.frame(anno)[, c("Name", "chr", "pos")]

dim(beta)
dim(anno_df)
rownames(anno_df) <- NULL
head(anno_df)
  1. 786553
  2. 130
  1. 786553
  2. 3
A data.frame: 6 × 3
Namechrpos
<chr><chr><int>
1cg18478105chr20 61847650
2cg14361672chr9 131463936
3cg01763666chr17 80159506
4cg12950382chr14105176736
5cg02115394chr13115000168
6cg13417420chr12 12849159
In [36]:
head(beta)
dim(beta)
A data.frame: 6 × 130
ID0022ID0262ID0393ID0439ID0479ID0494ID0511ID0824ID0879ID1075⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>⋯<dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl><dbl>
cg184781050.044937370.066761490.05069250.058392700.046561210.050411940.051938090.046584070.050605910.06310769⋯0.045625120.056042840.056134250.050653790.053624670.054163640.055906490.053412710.051632740.06120382
cg143616720.721733590.759846160.69230650.715978440.742338130.723293600.715620720.679430870.745100080.71969152⋯0.726706730.737098090.705352130.745818810.710711800.718692740.741084820.734338090.740714820.72361315
cg017636660.850854610.827507910.82976220.853815590.797000730.817304330.806208850.843390060.854725440.81193033⋯0.859207450.839721260.833400570.846646520.872298420.845204400.868964510.854316790.835421130.84568474
cg129503820.834233980.930070210.82916150.904139600.854069830.819054000.831567670.848787160.852507700.85984169⋯0.821294880.872148150.916340150.868005390.833847560.874383360.868753120.859441780.915559110.81581543
cg021153940.071682390.108149580.15305760.100834330.127769260.100710090.079348270.105522870.111188010.10977465⋯0.090399460.075309700.089627270.110693870.115671430.078814270.089382070.057794520.102840750.10721822
cg134174200.060761400.075543130.14288110.057981940.065471890.102195980.092891600.051792870.091675240.09668951⋯0.064694730.068313970.077296470.074517280.059532310.077866670.078823500.100279220.074192880.06533796
  1. 786553
  2. 130
In [13]:
colnames(ERA_phenodata.filtered)
  1. 'visit'
  2. 'follow_up'
  3. 't'
  4. 'studygroup'
  5. 'D_SEX'
  6. 'D_AGE'
  7. 'D_HEIGHT'
  8. 'D_WEIGHT'
  9. 'D_YN_HEALTHY'
  10. 'D_YN_ASTHMA'
  11. 'G_SEVERE_re'
  12. 'G_EOSINOPHILIC_ASTHMA'
  13. 'G_EOSINOPHILIC_ASTHMA_subset'
  14. 'D_ASTHMA_SEVERITYGRADE_SCREEN'
  15. 'D_ASTHMA_SEVERITYGRADE_SCREEN_subset'
  16. 'D_ASTHMA_ALLERGIC_SCREEN'
  17. 'D_GINA_Asthmakontrolle'
  18. 'D_GINA_Asthmakontrolle_re'
  19. 'D_GINA_Asthmakontrolle_re2'
  20. 'D_ALLERGIC_STATUS'
  21. 'Q2P_Exacerbations'
  22. 'Q2P_n_Exacerbations'
  23. 'Q2P_Exacerbations_12m_re'
  24. 'Q2P_EXACERBATIONS_12m_YN'
  25. 'D_ExSmoker_SinceYear'
  26. 'D_ExSmoker_SinceYear_subset'
  27. 'D_SmokingStatus'
  28. 'D_SmokingStatus_subset'
  29. 'D_YearsSmoked'
  30. 'D_CigarettesPerDay'
  31. 'D_Packyears'
  32. 'D_Packyears_subset'
  33. 'D_Packyears_re'
  34. 'D_Packyears_re2'
  35. 'D_Packyears_re3'
  36. 'D_SmokingStatus_re'
  37. 'D_SmokingStatus_re2'
  38. 'D_SmokingStatus_re3'
  39. 'D_SmokingStatus_re4'
  40. 'D_YN_CURRENTSMOKER'
  41. 'D_SMOKINGSTATUS_YN_CHANGES'
  42. 'D_CigarettesPerDay_Active'
  43. 'MB_DIFF_EOS_abs'
  44. 'MB_DIFF_EOS_abs_re'
  45. 'MB_DIFF_EOS_perc'
  46. 'MS_DIFF_EOS_YN'
  47. 'MS_DIFF_EOS'
  48. 'MS_DIFF_EOS_re'
  49. 'MS_DIFF_EOS_re2'
  50. 'MS_DIFF_EOS_re3'
  51. 'L_SPIRO_FEV1perc'
  52. 'L_SPIRO_FEV1_POST'
  53. 'L_SPIRO_FEV1perc_re'
  54. 'L_SPIRO_FEV1_FVC'
  55. 'L_SPIRO_FEV1_FVC_re'
  56. 'L_SPIRO_FVC'
  57. 'L_SPIRO_FVCperc'
  58. 'L_SPIRO_FEV1_POSTperc'
  59. 'L_SPIRO_FEF50'
  60. 'L_SPIRO_FEF50perc'
  61. 'L_BODY_RV_TLC'
  62. 'S_ACQ_SCORE_Q1'
  63. 'S_ACQ_SCORE_Q2'
  64. 'S_ACQ_SCORE_Q3'
  65. 'S_ACQ_SCORE_Q4'
  66. 'S_ACQ_SCORE_Q5'
  67. 'S_ACQ_SCORE_Q6'
  68. 'S_ACQ_6_TOTAL'
  69. 'S_ACQ_6_TOTAL_YN_UNCONTROLLED'
  70. 'S_ACQ_7_TOTAL'
  71. 'S_ACQ_7_YN_UNCONTROLLED'
  72. 'pseudo_ID'
  73. 'Sample_Plate'
  74. 'barcome'
  75. 'Array'
  76. 'Slide'
  77. 'id'
  78. 'Horvath'
  79. 'ageAcc.Horvath'
  80. 'residual.Horvath'
  81. 'Hannum'
  82. 'ageAcc.Hannum'
  83. 'residual.Hannum'
  84. 'Levine'
  85. 'ageAcc.Levine'
  86. 'residual.Levine'
  87. 'BNN'
  88. 'skinHorvath'
  89. 'ageAcc.skinHorvath'
  90. 'residual.skinHorvath'
  91. 'PedBE'
  92. 'ageAcc.PedBE'
  93. 'residual.PedBE'
  94. 'Wu'
  95. 'ageAcc.Wu'
  96. 'residual.Wu'
  97. 'TL'
  98. 'ageAcc.TL'
  99. 'residual.TL'
  100. 'BLUP'
  101. 'ageAcc.BLUP'
  102. 'residual.BLUP'
  103. 'EN'
  104. 'ageAcc.EN'
  105. 'residual.EN'
In [37]:
#preparing covaruate matrix for meqtl
pheno <- ERA_phenodata.filtered %>%
filter(pseudo_ID %in% colnames(beta)) %>%
distinct(pseudo_ID, .keep_all = TRUE) %>%
dplyr::select(D_AGE, D_SEX,  pseudo_ID, Sample_Plate)
pheno$Sample_Plate <- as.factor(pheno$Sample_Plate)
length(pheno$pseudo_ID)
130
In [15]:
head(pheno)
A data.frame: 6 × 4
D_AGED_SEXpseudo_IDSample_Plate
<int><int><chr><fct>
ID5100.t00651ID5100WG6997856-BCD
ID2828.t00730ID2828WG7006706-BCD
ID7549.t00711ID7549WG6997856-BCD
ID8478.t00671ID8478WG6997856-BCD
ID9318.t00640ID9318WG6997856-BCD
ID1520.t00680ID1520WG7006706-BCD
In [38]:
pheno$D_AGE <- as.numeric(pheno$D_AGE)
pheno$D_SEX <- as.numeric(pheno$D_SEX)
pheno$Sample_Plate <- as.factor(pheno$Sample_Plate)
In [39]:
row.names(pheno) <- pheno$pseudo_ID
pheno$pseudo_ID <- NULL
In [18]:
plate_dummy <- model.matrix(~ Sample_Plate, data = pheno)[, -1]
In [19]:
covariates <- cbind(
  D_AGE = pheno$D_AGE,
  D_SEX = pheno$D_SEX,
  plate_dummy
)

row.names(covariates) <- row.names(pheno)
In [20]:
head(covariates)
A matrix: 6 × 4 of type dbl
D_AGED_SEXSample_PlateWG7006706-BCDSample_PlateWG7011387-BCD
ID510065100
ID282873010
ID754971100
ID847867100
ID931864000
ID152068010
In [21]:
cvrt <- t(covariates)
head(cvrt)
A matrix: 4 × 130 of type dbl
ID5100ID2828ID7549ID8478ID9318ID1520ID9621ID5371ID1415ID0393⋯ID1467ID3972ID0439ID7438ID1295ID1267ID3404ID2230ID2386ID4803
D_AGE65737167646860595269⋯27292722656454495752
D_SEX 1 0 1 1 0 0 0 1 0 0⋯ 0 1 0 1 0 0 1 0 0 1
Sample_PlateWG7006706-BCD 0 1 0 0 0 1 0 0 1 0⋯ 0 0 1 1 1 0 0 1 1 0
Sample_PlateWG7011387-BCD 0 0 0 0 0 0 0 0 0 1⋯ 0 0 0 0 0 1 1 0 0 1
In [40]:
geno_M  <- geno[, com, drop = FALSE]
dim(geno_M)
  1. 5967986
  2. 130
In [41]:
head(geno_M)
head(snpspos)
A data.frame: 6 × 130
ID0022ID0262ID0393ID0439ID0479ID0494ID0511ID0824ID0879ID1075⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<int><int><int><int><int><int><int><int><int><int>⋯<int><int><int><int><int><int><int><int><int><int>
rs5752721510000000100⋯0000010011
rs5444190190000000100⋯0000010011
rs626352860001010010⋯0100000010
rs2005799490001010010⋯0100000010
rs5317308561100000000⋯1000001000
rs5461694440000000100⋯0001000001
A data.frame: 6 × 2
ChromosomePosition
<int><int>
rs575272151111008
rs544419019111012
rs62635286113116
rs200579949113118
rs531730856113273
rs546169444114464
In [42]:
snpspos <- cbind(id = rownames(snpspos), snpspos)
rownames(snpspos) <- NULL
head(snpspos)
A data.frame: 6 × 3
idChromosomePosition
<chr><int><int>
1rs575272151111008
2rs544419019111012
3rs62635286 113116
4rs200579949113118
5rs531730856113273
6rs546169444114464

Filtering CPGs overlapping snps

In [45]:
cpg_gr <- GRanges(
  seqnames = anno_df$chr,                 # e.g. "chr1"
  ranges   = IRanges(start = anno_df$pos, end = anno_df$pos),
  CpG      = anno_df$Name
)
In [46]:
snpspos$Chromosome <- paste0("chr", snpspos$Chromosome)

snp_gr <- GRanges(
  seqnames = snpspos$Chromosome,
  ranges   = IRanges(start = snpspos$Position, end = snpspos$Position),
  SNP      = snpspos$SNP
)
In [47]:
hits <- findOverlaps(cpg_gr, snp_gr)

# CpG IDs that have a SNP exactly at their CpG coordinate
bad_cpgs <- unique(mcols(cpg_gr)$CpG[queryHits(hits)])

head(bad_cpgs)
length(bad_cpgs)   # just to see how many are removed
  1. 'cg06559364'
  2. 'cg03110633'
  3. 'cg06697073'
  4. 'cg24694947'
  5. 'cg14041264'
  6. 'cg23851359'
1004
In [48]:
beta_filtered <- beta[!(rownames(beta) %in% bad_cpgs), ]
dim(beta_filtered)
  1. 785549
  2. 130
In [49]:
# Convert to long format
beta_long_f <- beta_filtered %>%
  as.data.frame() %>%
  mutate(CpG = rownames(.)) %>%
  pivot_longer(-CpG, names_to = "Sample", values_to = "Beta")
In [39]:
ggplot(beta_long_f, aes(x = Beta)) +
 scale_fill_viridis_c() +
  geom_histogram(bins = 60, color = "white") +
  labs(
    title = "Distribution of Dasen Normalized Beta Values",
    x = "Beta value",
    y = "Frequency"
  ) +
  theme_minimal()
In [29]:
anno_df <- anno_df[anno_df$Name %in% rownames(beta_filtered), ]
dim(anno_df)
  1. 785549
  2. 3
In [50]:
library(RNOmni)

beta_int <- t(apply(beta_filtered, 1, RankNorm))
In [31]:
head(beta_int)
A matrix: 6 × 130 of type dbl
ID0022ID0262ID0393ID0439ID0479ID0494ID0511ID0824ID0879ID1075⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
cg18478105-1.06696313 2.2421448-0.04813044 0.9699855-0.85333404-0.14484044 0.1838557-0.825955784-0.086709895 1.71485202⋯-1.0012651 0.7472802 0.8259558-0.06740763 0.4904714 0.55669604 0.7220731 0.4053494 0.067407627 1.50455851
cg14361672-0.04813044 1.2557323-0.79918308-0.1838557 0.67298051 0.02887113-0.2034650-1.345378982 0.772971331-0.08670989⋯ 0.2627979 0.4688799-0.4475049 0.82595578-0.3028605-0.12541888 0.6022241 0.4263324 0.556696037 0.04813044
cg01763666 0.44750489-0.6729805-0.60222414 0.6022241-1.91367115-1.21447042-1.5045585 0.009622522 0.772971331-1.39456256⋯ 0.9396272-0.1060445-0.3230715 0.16431679 1.9136711 0.06740763 1.7148520 0.6973167-0.223152902 0.12541888
cg12950382-0.46887992 2.5900238-0.62545898 1.9136711 0.06740763-0.77297133-0.5793100-0.028871131 0.009622522 0.26279793⋯-0.7472802 0.6022241 2.2421448 0.42633241-0.5343633 0.72207313 0.4904714 0.2231529 2.050587838-0.79918308
cg02115394-1.91367115 0.3434154 1.91367115-0.1254189 1.21447042-0.14484044-1.5671376 0.144840440 0.534363291 0.42633241⋯-0.7991831-1.8053670-0.8533340 0.51229395 0.8533340-1.63653605-0.8813674-2.5900238-0.009622522 0.28277249
cg13417420-1.00126511 0.2627979 1.56713759-1.2144704-0.60222414 1.06696313 0.7729713-2.242144800 0.747280213 0.91011111⋯-0.6729805-0.4263324 0.3434154 0.16431679-1.1376221 0.38454329 0.4263324 1.0012651 0.106044526-0.62545898
In [32]:
# Convert to long format
beta_long <- beta_int %>%
  as.data.frame() %>%
  mutate(CpG = rownames(.)) %>%
  pivot_longer(-CpG, names_to = "Sample", values_to = "Beta")
In [35]:
ggplot(beta_long, aes(x = Beta)) +
 scale_fill_viridis_c() +
  geom_histogram(bins = 60, color = "white") +
  labs(
    title = "Distribution of Inverse Rank Normalized Beta Values",
    x = "Beta value",
    y = "Frequency"
  ) +
  theme_minimal()
In [31]:
cpgpos <- data.frame(
  cpgid = anno_df$Name,
  chr    = anno_df$chr,
  s1     = anno_df$pos,
  s2     = anno_df$pos)   # CpGs are single positions, so start = end
head(cpgpos)
A data.frame: 6 × 4
cpgidchrs1s2
<chr><chr><int><int>
1cg18478105chr20 61847650 61847650
2cg14361672chr9 131463936131463936
3cg01763666chr17 80159506 80159506
4cg12950382chr14105176736105176736
5cg02115394chr13115000168115000168
6cg13417420chr12 12849159 12849159
In [32]:
library(MatrixEQTL)

as_sliced <- function(m, slice = 2000L) {
  sd <- SlicedData$new()
  sd$CreateFromMatrix(as.matrix(m))
  sd$ResliceCombined(slice)
  sd
}
snps_M <- as_sliced(geno_M)            # rows=SNPs, cols=samples
cvrt_M <- as_sliced(cvrt)  
beta_sliced <- as_sliced(beta_int)       # rows=probes, cols=samples
In [33]:
mqtls <- Matrix_eQTL_main(
  snps      = snps_M,
  gene      = beta_sliced,
  cvrt      = cvrt_M,
  useModel  = modelLINEAR,
  output_file_name      = "",
  pvOutputThreshold     = 0,          # cis only
  output_file_name.cis  = "cis_mQTL_IRN_hits.tsv",
  pvOutputThreshold.cis = 1,
  snpspos   = snpspos,
  genepos   = cpgpos,
  cisDist   = 5e5,
  errorCovariance = numeric(), 
	verbose = TRUE,
  pvalue.hist = "qqplot",
	min.pv.by.genesnp = FALSE,
	noFDRsaveMemory = FALSE)
Matching data files and location files

785549 of 785549 genes matched

5967986 of 5967986 SNPs matched


Task finished in 0.856 seconds

Reordering genes

Task finished in 6.658 seconds

Processing covariates

Task finished in 0.004 seconds

Processing gene expression data (imputation, residualization)

Task finished in 1.76 seconds

Creating output file(s)

Task finished in 26.906 seconds

Performing eQTL analysis

 0.00% done, 2,599,728 cis-eQTLs

 0.00% done, 2,635,909 cis-eQTLs

 0.03% done, 3,916,609 cis-eQTLs

 0.03% done, 5,656,805 cis-eQTLs

 0.06% done, 5,661,840 cis-eQTLs

 0.06% done, 8,011,129 cis-eQTLs

 0.06% done, 8,390,004 cis-eQTLs

 0.10% done, 9,163,912 cis-eQTLs

 0.10% done, 10,455,072 cis-eQTLs

 0.13% done, 11,092,502 cis-eQTLs

 0.16% done, 11,526,117 cis-eQTLs

 0.20% done, 12,384,372 cis-eQTLs

 0.23% done, 13,817,654 cis-eQTLs

 0.23% done, 14,264,474 cis-eQTLs

 0.26% done, 14,281,653 cis-eQTLs

 0.26% done, 15,263,897 cis-eQTLs

 0.30% done, 16,460,278 cis-eQTLs

 0.33% done, 17,677,304 cis-eQTLs

 0.33% done, 17,799,983 cis-eQTLs

 0.36% done, 17,835,945 cis-eQTLs

 0.36% done, 19,205,976 cis-eQTLs

 0.40% done, 20,721,022 cis-eQTLs

 0.43% done, 21,083,880 cis-eQTLs

 0.43% done, 21,220,919 cis-eQTLs

 0.46% done, 21,283,601 cis-eQTLs

 0.46% done, 21,742,488 cis-eQTLs

 0.50% done, 22,502,500 cis-eQTLs

 0.53% done, 23,924,670 cis-eQTLs

 0.57% done, 25,325,017 cis-eQTLs

 0.60% done, 26,203,171 cis-eQTLs

 0.60% done, 26,513,734 cis-eQTLs

 0.63% done, 26,670,250 cis-eQTLs

 0.63% done, 27,452,276 cis-eQTLs

 0.67% done, 28,506,798 cis-eQTLs

 0.70% done, 29,712,862 cis-eQTLs

 0.73% done, 30,810,307 cis-eQTLs

 0.77% done, 31,218,497 cis-eQTLs

 0.77% done, 31,870,367 cis-eQTLs

 0.80% done, 31,875,999 cis-eQTLs

 0.80% done, 33,031,623 cis-eQTLs

 0.83% done, 34,109,662 cis-eQTLs

 0.87% done, 35,270,992 cis-eQTLs

 0.87% done, 35,396,255 cis-eQTLs

 0.90% done, 35,570,235 cis-eQTLs

 0.90% done, 36,558,198 cis-eQTLs

 0.93% done, 38,132,128 cis-eQTLs

 0.93% done, 38,132,129 cis-eQTLs

 0.97% done, 38,446,723 cis-eQTLs

 0.97% done, 39,396,905 cis-eQTLs

 1.00% done, 40,163,445 cis-eQTLs

 1.03% done, 40,603,556 cis-eQTLs

 1.07% done, 41,493,126 cis-eQTLs

 1.07% done, 41,517,120 cis-eQTLs

 1.10% done, 41,891,106 cis-eQTLs

 1.10% done, 42,845,516 cis-eQTLs

 1.14% done, 43,643,715 cis-eQTLs

 1.17% done, 44,209,051 cis-eQTLs

 1.20% done, 44,356,619 cis-eQTLs

 1.20% done, 45,166,915 cis-eQTLs

 1.24% done, 46,137,640 cis-eQTLs

 1.27% done, 47,006,911 cis-eQTLs

 1.30% done, 47,711,656 cis-eQTLs

 1.30% done, 48,090,109 cis-eQTLs

 1.34% done, 48,115,606 cis-eQTLs

 1.34% done, 49,226,836 cis-eQTLs

 1.37% done, 50,167,489 cis-eQTLs

 1.40% done, 51,158,097 cis-eQTLs

 1.40% done, 51,167,402 cis-eQTLs

 1.44% done, 51,652,504 cis-eQTLs

 1.44% done, 52,570,047 cis-eQTLs

 1.47% done, 53,658,472 cis-eQTLs

 1.50% done, 54,701,380 cis-eQTLs

 1.50% done, 54,721,574 cis-eQTLs

 1.54% done, 54,943,327 cis-eQTLs

 1.54% done, 55,635,742 cis-eQTLs

 1.57% done, 56,074,887 cis-eQTLs

 1.60% done, 56,511,729 cis-eQTLs

 1.64% done, 57,342,317 cis-eQTLs

 1.64% done, 57,344,368 cis-eQTLs

 1.67% done, 57,823,995 cis-eQTLs

 1.67% done, 58,473,241 cis-eQTLs

 1.71% done, 59,656,484 cis-eQTLs

 1.74% done, 60,195,942 cis-eQTLs

 1.77% done, 60,636,871 cis-eQTLs

 1.81% done, 60,983,533 cis-eQTLs

 1.84% done, 61,337,695 cis-eQTLs

 1.87% done, 61,968,662 cis-eQTLs

 1.91% done, 62,207,694 cis-eQTLs

 1.91% done, 62,314,108 cis-eQTLs

 1.94% done, 62,752,980 cis-eQTLs

 1.97% done, 63,199,555 cis-eQTLs

 2.01% done, 63,739,836 cis-eQTLs

 2.04% done, 64,270,944 cis-eQTLs

 2.07% done, 64,886,064 cis-eQTLs

 2.11% done, 65,290,504 cis-eQTLs

 2.14% done, 65,857,021 cis-eQTLs

 2.17% done, 66,396,629 cis-eQTLs

 2.17% done, 66,467,779 cis-eQTLs

 2.21% done, 66,558,996 cis-eQTLs

 2.21% done, 66,766,793 cis-eQTLs

 2.24% done, 66,967,917 cis-eQTLs

 2.28% done, 67,230,479 cis-eQTLs

 2.31% done, 67,324,309 cis-eQTLs

 2.34% done, 67,386,376 cis-eQTLs

 2.38% done, 67,615,597 cis-eQTLs

 2.41% done, 67,977,542 cis-eQTLs

 2.44% done, 68,272,604 cis-eQTLs

 2.48% done, 68,649,535 cis-eQTLs

 2.51% done, 69,043,958 cis-eQTLs

 2.54% done, 69,203,165 cis-eQTLs

 2.58% done, 69,278,618 cis-eQTLs

 2.61% done, 69,411,512 cis-eQTLs

 2.64% done, 69,643,662 cis-eQTLs

 2.68% done, 69,730,277 cis-eQTLs

 2.71% done, 69,888,058 cis-eQTLs

 2.74% done, 70,364,301 cis-eQTLs

 2.74% done, 70,470,799 cis-eQTLs

 2.78% done, 70,576,568 cis-eQTLs

 2.78% done, 71,125,775 cis-eQTLs

 2.81% done, 71,462,172 cis-eQTLs

 2.85% done, 71,906,093 cis-eQTLs

 2.88% done, 72,153,688 cis-eQTLs

 2.91% done, 72,695,849 cis-eQTLs

 2.95% done, 73,156,285 cis-eQTLs

 2.98% done, 73,683,155 cis-eQTLs

 3.01% done, 74,274,821 cis-eQTLs

 3.01% done, 74,294,967 cis-eQTLs

 3.05% done, 74,412,815 cis-eQTLs

 3.05% done, 75,078,143 cis-eQTLs

 3.08% done, 75,744,473 cis-eQTLs

 3.11% done, 76,029,613 cis-eQTLs

 3.15% done, 76,200,444 cis-eQTLs

 3.18% done, 76,384,437 cis-eQTLs

 3.21% done, 76,583,343 cis-eQTLs

 3.25% done, 77,075,625 cis-eQTLs

 3.28% done, 77,563,312 cis-eQTLs

 3.31% done, 77,781,889 cis-eQTLs

 3.35% done, 77,841,446 cis-eQTLs

 3.38% done, 77,924,880 cis-eQTLs

 3.41% done, 77,954,027 cis-eQTLs

 3.45% done, 77,978,407 cis-eQTLs

 3.48% done, 78,036,107 cis-eQTLs

 3.52% done, 78,238,832 cis-eQTLs

 3.52% done, 78,262,853 cis-eQTLs

 3.55% done, 78,331,541 cis-eQTLs

 3.55% done, 78,602,972 cis-eQTLs

 3.58% done, 79,590,341 cis-eQTLs

 3.62% done, 80,891,574 cis-eQTLs

 3.65% done, 81,761,562 cis-eQTLs

 3.68% done, 82,470,254 cis-eQTLs

 3.68% done, 82,562,678 cis-eQTLs

 3.72% done, 82,633,065 cis-eQTLs

 3.72% done, 83,253,660 cis-eQTLs

 3.75% done, 83,877,298 cis-eQTLs

 3.78% done, 84,448,201 cis-eQTLs

 3.82% done, 85,086,611 cis-eQTLs

 3.85% done, 85,739,018 cis-eQTLs

 3.88% done, 85,972,934 cis-eQTLs

 3.88% done, 86,056,358 cis-eQTLs

 3.92% done, 86,114,319 cis-eQTLs

 3.92% done, 86,573,642 cis-eQTLs

 3.95% done, 86,686,241 cis-eQTLs

 3.98% done, 87,145,442 cis-eQTLs

 4.02% done, 87,548,283 cis-eQTLs

 4.05% done, 88,407,124 cis-eQTLs

 4.05% done, 88,434,301 cis-eQTLs

 4.09% done, 88,672,329 cis-eQTLs

 4.09% done, 89,748,099 cis-eQTLs

 4.12% done, 90,537,222 cis-eQTLs

 4.15% done, 91,753,725 cis-eQTLs

 4.15% done, 91,862,000 cis-eQTLs

 4.19% done, 92,028,149 cis-eQTLs

 4.19% done, 93,487,895 cis-eQTLs

 4.22% done, 94,420,963 cis-eQTLs

 4.22% done, 95,146,406 cis-eQTLs

 4.25% done, 95,766,023 cis-eQTLs

 4.29% done, 96,331,697 cis-eQTLs

 4.32% done, 96,832,686 cis-eQTLs

 4.35% done, 97,944,716 cis-eQTLs

 4.39% done, 98,643,292 cis-eQTLs

 4.39% done, 99,293,732 cis-eQTLs

 4.42% done, 99,335,067 cis-eQTLs

 4.42% done, 100,233,051 cis-eQTLs

 4.45% done, 100,823,836 cis-eQTLs

 4.49% done, 101,094,458 cis-eQTLs

 4.52% done, 101,386,993 cis-eQTLs

 4.55% done, 102,016,766 cis-eQTLs

 4.59% done, 102,510,594 cis-eQTLs

 4.62% done, 103,101,650 cis-eQTLs

 4.62% done, 103,146,855 cis-eQTLs

 4.66% done, 103,391,018 cis-eQTLs

 4.66% done, 103,926,140 cis-eQTLs

 4.69% done, 104,368,051 cis-eQTLs

 4.72% done, 104,893,725 cis-eQTLs

 4.76% done, 105,326,197 cis-eQTLs

 4.79% done, 105,773,032 cis-eQTLs

 4.82% done, 106,259,769 cis-eQTLs

 4.86% done, 106,724,438 cis-eQTLs

 4.89% done, 107,184,029 cis-eQTLs

 4.92% done, 107,619,844 cis-eQTLs

 4.92% done, 107,695,037 cis-eQTLs

 4.96% done, 107,717,059 cis-eQTLs

 4.96% done, 107,948,785 cis-eQTLs

 4.99% done, 108,250,198 cis-eQTLs

 5.02% done, 108,769,264 cis-eQTLs

 5.06% done, 109,432,392 cis-eQTLs

 5.09% done, 110,120,749 cis-eQTLs

 5.12% done, 110,801,333 cis-eQTLs

 5.16% done, 111,357,719 cis-eQTLs

 5.19% done, 111,831,700 cis-eQTLs

 5.19% done, 112,104,331 cis-eQTLs

 5.23% done, 112,107,900 cis-eQTLs

 5.23% done, 112,681,644 cis-eQTLs

 5.26% done, 113,155,067 cis-eQTLs

 5.29% done, 113,465,585 cis-eQTLs

 5.33% done, 113,594,798 cis-eQTLs

 5.36% done, 113,668,534 cis-eQTLs

 5.39% done, 113,732,813 cis-eQTLs

 5.43% done, 113,825,008 cis-eQTLs

 5.46% done, 113,901,877 cis-eQTLs

 5.49% done, 113,963,460 cis-eQTLs

 5.53% done, 114,324,491 cis-eQTLs

 5.56% done, 114,433,424 cis-eQTLs

 5.59% done, 114,477,632 cis-eQTLs

 5.63% done, 114,537,071 cis-eQTLs

 5.66% done, 114,707,237 cis-eQTLs

 5.69% done, 115,133,678 cis-eQTLs

 5.73% done, 115,390,936 cis-eQTLs

 5.73% done, 115,517,091 cis-eQTLs

 5.76% done, 115,871,136 cis-eQTLs

 5.80% done, 116,663,573 cis-eQTLs

 5.83% done, 118,026,878 cis-eQTLs

 5.86% done, 119,142,619 cis-eQTLs

 5.86% done, 119,158,841 cis-eQTLs

 5.90% done, 119,634,123 cis-eQTLs

 5.90% done, 120,336,963 cis-eQTLs

 5.93% done, 121,537,301 cis-eQTLs

 5.96% done, 122,760,200 cis-eQTLs

 6.00% done, 123,355,327 cis-eQTLs

 6.00% done, 123,624,475 cis-eQTLs

 6.03% done, 123,624,760 cis-eQTLs

 6.03% done, 124,288,229 cis-eQTLs

 6.06% done, 124,703,951 cis-eQTLs

 6.10% done, 125,342,360 cis-eQTLs

 6.13% done, 125,736,614 cis-eQTLs

 6.16% done, 126,508,665 cis-eQTLs

 6.20% done, 127,323,542 cis-eQTLs

 6.20% done, 127,359,165 cis-eQTLs

 6.23% done, 127,375,067 cis-eQTLs

 6.23% done, 127,860,622 cis-eQTLs

 6.26% done, 128,304,090 cis-eQTLs

 6.30% done, 128,505,557 cis-eQTLs

 6.33% done, 128,806,450 cis-eQTLs

 6.37% done, 129,100,598 cis-eQTLs

 6.40% done, 129,449,826 cis-eQTLs

 6.43% done, 129,815,620 cis-eQTLs

 6.47% done, 130,385,488 cis-eQTLs

 6.50% done, 130,846,187 cis-eQTLs

 6.53% done, 131,327,188 cis-eQTLs

 6.53% done, 131,354,821 cis-eQTLs

 6.57% done, 131,536,003 cis-eQTLs

 6.57% done, 131,973,304 cis-eQTLs

 6.60% done, 132,539,144 cis-eQTLs

 6.63% done, 133,193,404 cis-eQTLs

 6.67% done, 134,176,038 cis-eQTLs

 6.70% done, 134,846,635 cis-eQTLs

 6.73% done, 135,614,264 cis-eQTLs

 6.73% done, 136,149,474 cis-eQTLs

 6.77% done, 136,150,305 cis-eQTLs

 6.77% done, 137,016,553 cis-eQTLs

 6.80% done, 137,844,406 cis-eQTLs

 6.83% done, 138,750,896 cis-eQTLs

 6.87% done, 139,292,805 cis-eQTLs

 6.90% done, 139,784,359 cis-eQTLs

 6.90% done, 139,837,797 cis-eQTLs

 6.94% done, 139,951,179 cis-eQTLs

 6.94% done, 140,263,401 cis-eQTLs

 6.97% done, 140,995,584 cis-eQTLs

 7.00% done, 141,844,317 cis-eQTLs

 7.04% done, 142,678,279 cis-eQTLs

 7.07% done, 143,279,058 cis-eQTLs

 7.10% done, 143,539,134 cis-eQTLs

 7.14% done, 143,704,434 cis-eQTLs

 7.17% done, 143,846,068 cis-eQTLs

 7.20% done, 144,215,712 cis-eQTLs

 7.24% done, 144,610,157 cis-eQTLs

 7.27% done, 144,888,527 cis-eQTLs

 7.27% done, 145,044,603 cis-eQTLs

 7.30% done, 145,100,893 cis-eQTLs

 7.30% done, 145,408,755 cis-eQTLs

 7.34% done, 145,630,947 cis-eQTLs

 7.37% done, 146,193,792 cis-eQTLs

 7.40% done, 146,904,185 cis-eQTLs

 7.44% done, 147,616,180 cis-eQTLs

 7.47% done, 148,239,988 cis-eQTLs

 7.50% done, 149,021,250 cis-eQTLs

 7.54% done, 149,859,499 cis-eQTLs

 7.57% done, 150,359,787 cis-eQTLs

 7.57% done, 150,393,371 cis-eQTLs

 7.61% done, 150,480,149 cis-eQTLs

 7.61% done, 150,916,778 cis-eQTLs

 7.64% done, 152,179,921 cis-eQTLs

 7.67% done, 153,329,567 cis-eQTLs

 7.71% done, 154,492,527 cis-eQTLs

 7.74% done, 155,162,555 cis-eQTLs

 7.77% done, 155,910,768 cis-eQTLs

 7.77% done, 156,557,845 cis-eQTLs

 7.81% done, 156,662,965 cis-eQTLs

 7.81% done, 157,521,486 cis-eQTLs

 7.84% done, 157,639,804 cis-eQTLs

 7.87% done, 157,877,573 cis-eQTLs

 7.91% done, 158,227,226 cis-eQTLs

 7.94% done, 158,712,261 cis-eQTLs

 7.97% done, 159,229,635 cis-eQTLs

 8.01% done, 160,168,724 cis-eQTLs

 8.01% done, 160,172,214 cis-eQTLs

 8.04% done, 160,756,199 cis-eQTLs

 8.04% done, 161,367,144 cis-eQTLs

 8.07% done, 161,419,477 cis-eQTLs

 8.07% done, 162,618,821 cis-eQTLs

 8.11% done, 163,699,797 cis-eQTLs

 8.14% done, 164,583,383 cis-eQTLs

 8.18% done, 164,948,885 cis-eQTLs

 8.21% done, 165,060,540 cis-eQTLs

 8.24% done, 165,184,604 cis-eQTLs

 8.28% done, 165,493,368 cis-eQTLs

 8.31% done, 166,035,368 cis-eQTLs

 8.31% done, 166,035,382 cis-eQTLs

 8.34% done, 166,251,076 cis-eQTLs

 8.34% done, 166,349,147 cis-eQTLs

 8.38% done, 166,349,171 cis-eQTLs

 8.38% done, 166,730,695 cis-eQTLs

 8.41% done, 167,036,134 cis-eQTLs

 8.44% done, 167,576,599 cis-eQTLs

 8.48% done, 168,439,744 cis-eQTLs

 8.51% done, 168,733,440 cis-eQTLs

 8.54% done, 168,981,964 cis-eQTLs

 8.58% done, 169,761,141 cis-eQTLs

 8.61% done, 170,361,173 cis-eQTLs

 8.61% done, 170,666,087 cis-eQTLs

 8.64% done, 170,672,333 cis-eQTLs

 8.64% done, 171,676,762 cis-eQTLs

 8.68% done, 172,909,977 cis-eQTLs

 8.68% done, 172,919,023 cis-eQTLs

 8.71% done, 173,279,650 cis-eQTLs

 8.71% done, 173,707,391 cis-eQTLs

 8.75% done, 173,707,820 cis-eQTLs

 8.75% done, 174,165,965 cis-eQTLs

 8.78% done, 174,702,434 cis-eQTLs

 8.81% done, 175,168,125 cis-eQTLs

 8.85% done, 175,616,540 cis-eQTLs

 8.88% done, 176,031,726 cis-eQTLs

 8.91% done, 176,211,649 cis-eQTLs

 8.95% done, 176,275,222 cis-eQTLs

 8.98% done, 176,337,005 cis-eQTLs

 9.01% done, 176,475,343 cis-eQTLs

 9.05% done, 177,011,671 cis-eQTLs

 9.08% done, 177,711,619 cis-eQTLs

 9.08% done, 177,767,259 cis-eQTLs

 9.11% done, 178,097,719 cis-eQTLs

 9.11% done, 178,572,617 cis-eQTLs

 9.15% done, 179,137,540 cis-eQTLs

 9.18% done, 179,433,026 cis-eQTLs

 9.21% done, 179,570,834 cis-eQTLs

 9.25% done, 180,051,274 cis-eQTLs

 9.28% done, 180,810,590 cis-eQTLs

 9.32% done, 181,697,896 cis-eQTLs

 9.35% done, 182,288,515 cis-eQTLs

 9.38% done, 182,784,216 cis-eQTLs

 9.38% done, 183,059,456 cis-eQTLs

 9.42% done, 183,167,628 cis-eQTLs

 9.42% done, 183,777,093 cis-eQTLs

 9.45% done, 184,663,126 cis-eQTLs

 9.48% done, 185,645,490 cis-eQTLs

 9.52% done, 186,177,067 cis-eQTLs

 9.55% done, 186,521,938 cis-eQTLs

 9.58% done, 186,619,176 cis-eQTLs

 9.62% done, 186,778,685 cis-eQTLs

 9.65% done, 186,964,368 cis-eQTLs

 9.68% done, 187,038,086 cis-eQTLs

 9.72% done, 187,134,895 cis-eQTLs

 9.75% done, 187,331,956 cis-eQTLs

 9.78% done, 187,781,815 cis-eQTLs

 9.78% done, 187,845,584 cis-eQTLs

 9.82% done, 188,019,145 cis-eQTLs

 9.82% done, 188,596,733 cis-eQTLs

 9.85% done, 189,128,134 cis-eQTLs

 9.89% done, 189,272,747 cis-eQTLs

 9.92% done, 189,332,645 cis-eQTLs

 9.95% done, 189,562,820 cis-eQTLs

 9.99% done, 189,733,647 cis-eQTLs

10.02% done, 190,176,420 cis-eQTLs

10.05% done, 190,764,518 cis-eQTLs

10.09% done, 191,274,261 cis-eQTLs

10.12% done, 191,678,539 cis-eQTLs

10.12% done, 191,898,722 cis-eQTLs

10.15% done, 191,910,798 cis-eQTLs

10.15% done, 192,722,998 cis-eQTLs

10.19% done, 193,149,707 cis-eQTLs

10.22% done, 193,557,431 cis-eQTLs

10.25% done, 193,943,654 cis-eQTLs

10.29% done, 194,600,211 cis-eQTLs

10.32% done, 195,400,304 cis-eQTLs

10.32% done, 195,411,209 cis-eQTLs

10.35% done, 195,800,701 cis-eQTLs

10.35% done, 196,422,442 cis-eQTLs

10.39% done, 196,426,382 cis-eQTLs

10.39% done, 197,334,338 cis-eQTLs

10.42% done, 197,900,245 cis-eQTLs

10.45% done, 198,961,210 cis-eQTLs

10.46% done, 198,969,216 cis-eQTLs

10.49% done, 199,364,289 cis-eQTLs

10.49% done, 199,853,920 cis-eQTLs

10.52% done, 200,183,031 cis-eQTLs

10.56% done, 200,266,670 cis-eQTLs

10.59% done, 200,336,242 cis-eQTLs

10.62% done, 200,386,083 cis-eQTLs

10.66% done, 200,537,190 cis-eQTLs

10.69% done, 200,789,505 cis-eQTLs

10.72% done, 201,001,956 cis-eQTLs

10.76% done, 201,093,200 cis-eQTLs

10.79% done, 201,157,503 cis-eQTLs

10.82% done, 201,204,484 cis-eQTLs

10.86% done, 201,351,275 cis-eQTLs

10.89% done, 202,403,309 cis-eQTLs

10.92% done, 203,458,333 cis-eQTLs

10.96% done, 203,573,536 cis-eQTLs

10.96% done, 203,749,288 cis-eQTLs

10.99% done, 204,096,404 cis-eQTLs

11.02% done, 204,602,957 cis-eQTLs

11.06% done, 205,321,250 cis-eQTLs

11.09% done, 205,701,097 cis-eQTLs

11.09% done, 205,981,793 cis-eQTLs

11.13% done, 206,548,481 cis-eQTLs

11.16% done, 207,372,413 cis-eQTLs

11.19% done, 208,173,404 cis-eQTLs

11.23% done, 208,621,681 cis-eQTLs

11.26% done, 208,966,899 cis-eQTLs

11.29% done, 209,732,392 cis-eQTLs

11.29% done, 209,807,544 cis-eQTLs

11.33% done, 210,072,210 cis-eQTLs

11.33% done, 210,462,699 cis-eQTLs

11.36% done, 210,751,420 cis-eQTLs

11.39% done, 211,002,202 cis-eQTLs

11.43% done, 211,625,021 cis-eQTLs

11.46% done, 212,092,797 cis-eQTLs

11.49% done, 212,593,140 cis-eQTLs

11.53% done, 213,530,871 cis-eQTLs

11.53% done, 213,531,231 cis-eQTLs

11.56% done, 213,859,595 cis-eQTLs

11.56% done, 214,093,387 cis-eQTLs

11.59% done, 214,095,411 cis-eQTLs

11.59% done, 214,276,646 cis-eQTLs

11.63% done, 214,335,863 cis-eQTLs

11.66% done, 214,376,738 cis-eQTLs

11.70% done, 214,693,446 cis-eQTLs

11.73% done, 215,274,740 cis-eQTLs

11.76% done, 216,090,019 cis-eQTLs

11.80% done, 217,196,325 cis-eQTLs

11.83% done, 217,694,397 cis-eQTLs

11.86% done, 217,758,354 cis-eQTLs

11.86% done, 217,784,786 cis-eQTLs

11.90% done, 217,785,667 cis-eQTLs

11.90% done, 217,854,616 cis-eQTLs

11.93% done, 217,953,127 cis-eQTLs

11.96% done, 218,015,914 cis-eQTLs

12.00% done, 218,098,171 cis-eQTLs

12.03% done, 218,668,301 cis-eQTLs

12.06% done, 219,752,491 cis-eQTLs

12.10% done, 220,391,502 cis-eQTLs

12.13% done, 220,656,700 cis-eQTLs

12.16% done, 221,164,096 cis-eQTLs

12.20% done, 221,479,319 cis-eQTLs

12.23% done, 221,790,435 cis-eQTLs

12.27% done, 221,936,771 cis-eQTLs

12.27% done, 222,158,786 cis-eQTLs

12.30% done, 222,159,922 cis-eQTLs

12.30% done, 222,638,441 cis-eQTLs

12.33% done, 223,087,708 cis-eQTLs

12.37% done, 223,293,077 cis-eQTLs

12.40% done, 223,430,137 cis-eQTLs

12.43% done, 223,672,715 cis-eQTLs

12.47% done, 223,753,919 cis-eQTLs

12.50% done, 223,827,055 cis-eQTLs

12.53% done, 223,901,615 cis-eQTLs

12.57% done, 224,000,495 cis-eQTLs

12.60% done, 224,187,739 cis-eQTLs

12.63% done, 224,621,818 cis-eQTLs

12.67% done, 224,794,651 cis-eQTLs

12.70% done, 225,003,207 cis-eQTLs

12.73% done, 225,199,422 cis-eQTLs

12.73% done, 225,339,070 cis-eQTLs

12.77% done, 225,342,119 cis-eQTLs

12.77% done, 225,648,078 cis-eQTLs

12.80% done, 225,998,646 cis-eQTLs

12.83% done, 226,469,775 cis-eQTLs

12.87% done, 226,844,995 cis-eQTLs

12.90% done, 227,032,608 cis-eQTLs

12.94% done, 227,185,373 cis-eQTLs

12.97% done, 227,270,975 cis-eQTLs

13.00% done, 227,595,986 cis-eQTLs

13.04% done, 227,980,367 cis-eQTLs

13.07% done, 228,437,451 cis-eQTLs

13.10% done, 228,922,079 cis-eQTLs

13.10% done, 228,949,439 cis-eQTLs

13.14% done, 229,156,365 cis-eQTLs

13.14% done, 229,460,014 cis-eQTLs

13.17% done, 229,877,710 cis-eQTLs

13.20% done, 230,037,278 cis-eQTLs

13.24% done, 230,331,698 cis-eQTLs

13.27% done, 230,686,394 cis-eQTLs

13.30% done, 230,911,407 cis-eQTLs

13.34% done, 231,187,838 cis-eQTLs

13.37% done, 231,692,608 cis-eQTLs

13.40% done, 232,267,153 cis-eQTLs

13.44% done, 232,803,780 cis-eQTLs

13.44% done, 232,806,382 cis-eQTLs

13.47% done, 233,098,522 cis-eQTLs

13.47% done, 233,418,395 cis-eQTLs

13.51% done, 234,197,825 cis-eQTLs

13.54% done, 234,776,207 cis-eQTLs

13.57% done, 235,392,731 cis-eQTLs

13.61% done, 235,930,622 cis-eQTLs

13.64% done, 236,966,599 cis-eQTLs

13.67% done, 237,167,483 cis-eQTLs

13.67% done, 237,476,264 cis-eQTLs

13.71% done, 238,015,131 cis-eQTLs

13.74% done, 238,371,063 cis-eQTLs

13.77% done, 238,624,590 cis-eQTLs

13.81% done, 238,865,164 cis-eQTLs

13.84% done, 239,287,681 cis-eQTLs

13.87% done, 239,613,470 cis-eQTLs

13.91% done, 239,755,111 cis-eQTLs

13.94% done, 239,830,717 cis-eQTLs

13.97% done, 239,945,917 cis-eQTLs

14.01% done, 240,215,109 cis-eQTLs

14.04% done, 240,394,934 cis-eQTLs

14.08% done, 240,762,570 cis-eQTLs

14.08% done, 240,766,179 cis-eQTLs

14.11% done, 240,907,171 cis-eQTLs

14.11% done, 241,409,729 cis-eQTLs

14.14% done, 241,876,456 cis-eQTLs

14.18% done, 241,938,708 cis-eQTLs

14.21% done, 242,035,331 cis-eQTLs

14.24% done, 242,441,023 cis-eQTLs

14.28% done, 243,005,298 cis-eQTLs

14.31% done, 243,246,286 cis-eQTLs

14.34% done, 243,882,464 cis-eQTLs

14.34% done, 244,022,669 cis-eQTLs

14.38% done, 244,070,838 cis-eQTLs

14.38% done, 244,853,550 cis-eQTLs

14.41% done, 245,322,121 cis-eQTLs

14.44% done, 245,619,198 cis-eQTLs

14.48% done, 246,044,351 cis-eQTLs

14.51% done, 246,644,838 cis-eQTLs

14.54% done, 247,325,886 cis-eQTLs

14.54% done, 247,425,152 cis-eQTLs

14.58% done, 247,539,375 cis-eQTLs

14.58% done, 247,799,740 cis-eQTLs

14.61% done, 248,025,918 cis-eQTLs

14.65% done, 248,314,975 cis-eQTLs

14.68% done, 248,394,175 cis-eQTLs

14.71% done, 248,504,424 cis-eQTLs

14.75% done, 248,794,613 cis-eQTLs

14.78% done, 248,892,704 cis-eQTLs

14.81% done, 249,182,664 cis-eQTLs

14.85% done, 249,922,407 cis-eQTLs

14.88% done, 250,664,339 cis-eQTLs

14.91% done, 251,295,027 cis-eQTLs

14.91% done, 251,562,895 cis-eQTLs

14.95% done, 251,600,365 cis-eQTLs

14.95% done, 253,288,778 cis-eQTLs

14.98% done, 253,715,850 cis-eQTLs

15.01% done, 253,891,856 cis-eQTLs

15.05% done, 254,347,571 cis-eQTLs

15.08% done, 254,712,027 cis-eQTLs

15.08% done, 254,809,578 cis-eQTLs

15.11% done, 254,832,551 cis-eQTLs

15.11% done, 255,268,940 cis-eQTLs

15.15% done, 255,697,676 cis-eQTLs

15.18% done, 255,915,928 cis-eQTLs

15.22% done, 256,329,161 cis-eQTLs

15.25% done, 256,903,888 cis-eQTLs

15.28% done, 257,221,907 cis-eQTLs

15.32% done, 257,411,842 cis-eQTLs

15.35% done, 257,925,149 cis-eQTLs

15.38% done, 258,775,593 cis-eQTLs

15.42% done, 259,493,135 cis-eQTLs

15.42% done, 259,848,300 cis-eQTLs

15.45% done, 259,858,046 cis-eQTLs

15.45% done, 260,869,754 cis-eQTLs

15.48% done, 261,955,314 cis-eQTLs

15.52% done, 262,642,645 cis-eQTLs

15.55% done, 263,314,047 cis-eQTLs

15.58% done, 264,131,681 cis-eQTLs

15.58% done, 264,268,084 cis-eQTLs

15.62% done, 264,430,839 cis-eQTLs

15.62% done, 265,165,832 cis-eQTLs

15.65% done, 266,201,268 cis-eQTLs

15.68% done, 267,606,005 cis-eQTLs

15.72% done, 268,827,570 cis-eQTLs

15.72% done, 269,007,523 cis-eQTLs

15.75% done, 269,596,706 cis-eQTLs

15.75% done, 270,527,437 cis-eQTLs

15.78% done, 271,825,893 cis-eQTLs

15.82% done, 273,604,558 cis-eQTLs

15.85% done, 275,098,023 cis-eQTLs

15.85% done, 275,697,131 cis-eQTLs

15.89% done, 275,971,022 cis-eQTLs

15.89% done, 276,636,308 cis-eQTLs

15.92% done, 276,767,478 cis-eQTLs

15.95% done, 276,835,860 cis-eQTLs

15.99% done, 276,930,971 cis-eQTLs

16.02% done, 277,087,960 cis-eQTLs

16.05% done, 277,381,041 cis-eQTLs

16.09% done, 277,658,436 cis-eQTLs

16.12% done, 278,013,691 cis-eQTLs

16.15% done, 278,711,535 cis-eQTLs

16.19% done, 278,962,963 cis-eQTLs

16.22% done, 279,050,532 cis-eQTLs

16.25% done, 279,182,618 cis-eQTLs

16.29% done, 279,299,308 cis-eQTLs

16.32% done, 279,572,653 cis-eQTLs

16.35% done, 280,242,153 cis-eQTLs

16.39% done, 280,669,726 cis-eQTLs

16.39% done, 281,442,120 cis-eQTLs

16.42% done, 281,446,652 cis-eQTLs

16.42% done, 282,571,356 cis-eQTLs

16.46% done, 283,339,726 cis-eQTLs

16.49% done, 284,215,940 cis-eQTLs

16.52% done, 285,074,510 cis-eQTLs

16.52% done, 285,421,431 cis-eQTLs

16.56% done, 285,515,841 cis-eQTLs

16.56% done, 286,412,074 cis-eQTLs

16.59% done, 287,413,217 cis-eQTLs

16.62% done, 288,123,733 cis-eQTLs

16.66% done, 288,740,119 cis-eQTLs

16.69% done, 289,041,463 cis-eQTLs

16.72% done, 289,259,749 cis-eQTLs

16.76% done, 289,529,552 cis-eQTLs

16.79% done, 289,645,278 cis-eQTLs

16.79% done, 289,647,104 cis-eQTLs

16.82% done, 289,689,290 cis-eQTLs

16.82% done, 289,774,110 cis-eQTLs

16.86% done, 289,784,446 cis-eQTLs

16.86% done, 289,938,031 cis-eQTLs

16.89% done, 290,074,234 cis-eQTLs

16.92% done, 290,414,916 cis-eQTLs

16.96% done, 290,907,690 cis-eQTLs

16.99% done, 291,194,908 cis-eQTLs

17.03% done, 291,519,432 cis-eQTLs

17.06% done, 291,683,488 cis-eQTLs

17.09% done, 292,122,870 cis-eQTLs

17.13% done, 292,387,740 cis-eQTLs

17.16% done, 292,590,372 cis-eQTLs

17.19% done, 292,831,151 cis-eQTLs

17.23% done, 293,187,795 cis-eQTLs

17.26% done, 293,757,006 cis-eQTLs

17.29% done, 294,360,194 cis-eQTLs

17.29% done, 294,461,663 cis-eQTLs

17.33% done, 294,541,712 cis-eQTLs

17.33% done, 294,904,528 cis-eQTLs

17.36% done, 294,983,249 cis-eQTLs

17.39% done, 295,177,208 cis-eQTLs

17.43% done, 295,518,908 cis-eQTLs

17.46% done, 296,244,626 cis-eQTLs

17.49% done, 296,998,704 cis-eQTLs

17.53% done, 297,523,137 cis-eQTLs

17.56% done, 297,876,799 cis-eQTLs

17.60% done, 298,101,140 cis-eQTLs

17.60% done, 298,475,981 cis-eQTLs

17.63% done, 298,507,340 cis-eQTLs

17.63% done, 299,439,655 cis-eQTLs

17.66% done, 300,129,699 cis-eQTLs

17.70% done, 301,018,440 cis-eQTLs

17.73% done, 301,843,787 cis-eQTLs

17.73% done, 302,047,631 cis-eQTLs

17.76% done, 302,224,001 cis-eQTLs

17.76% done, 303,153,374 cis-eQTLs

17.80% done, 303,996,977 cis-eQTLs

17.80% done, 304,864,766 cis-eQTLs

17.83% done, 305,857,416 cis-eQTLs

17.83% done, 305,942,915 cis-eQTLs

17.86% done, 306,145,433 cis-eQTLs

17.86% done, 306,899,478 cis-eQTLs

17.90% done, 307,325,852 cis-eQTLs

17.93% done, 307,798,644 cis-eQTLs

17.96% done, 308,171,492 cis-eQTLs

18.00% done, 308,824,109 cis-eQTLs

18.03% done, 309,678,827 cis-eQTLs

18.06% done, 310,096,849 cis-eQTLs

18.06% done, 310,120,453 cis-eQTLs

18.10% done, 310,178,705 cis-eQTLs

18.10% done, 310,290,623 cis-eQTLs

18.13% done, 310,290,713 cis-eQTLs

18.13% done, 310,427,386 cis-eQTLs

18.17% done, 310,644,422 cis-eQTLs

18.20% done, 311,112,114 cis-eQTLs

18.23% done, 311,510,054 cis-eQTLs

18.27% done, 311,990,036 cis-eQTLs

18.30% done, 312,545,146 cis-eQTLs

18.33% done, 312,870,654 cis-eQTLs

18.37% done, 313,333,730 cis-eQTLs

18.40% done, 313,666,757 cis-eQTLs

18.43% done, 313,845,707 cis-eQTLs

18.47% done, 314,106,097 cis-eQTLs

18.50% done, 314,593,742 cis-eQTLs

18.53% done, 314,804,181 cis-eQTLs

18.53% done, 314,905,496 cis-eQTLs

18.57% done, 314,944,484 cis-eQTLs

18.57% done, 315,654,440 cis-eQTLs

18.60% done, 316,307,061 cis-eQTLs

18.63% done, 316,717,096 cis-eQTLs

18.67% done, 316,848,648 cis-eQTLs

18.70% done, 316,907,164 cis-eQTLs

18.73% done, 316,981,580 cis-eQTLs

18.77% done, 317,129,488 cis-eQTLs

18.80% done, 317,264,842 cis-eQTLs

18.84% done, 317,414,694 cis-eQTLs

18.87% done, 317,482,750 cis-eQTLs

18.90% done, 317,620,835 cis-eQTLs

18.94% done, 317,699,026 cis-eQTLs

18.97% done, 317,730,747 cis-eQTLs

19.00% done, 317,805,567 cis-eQTLs

19.04% done, 317,892,820 cis-eQTLs

19.07% done, 317,962,494 cis-eQTLs

19.10% done, 318,166,475 cis-eQTLs

19.14% done, 318,378,403 cis-eQTLs

19.17% done, 318,481,747 cis-eQTLs

19.20% done, 318,585,623 cis-eQTLs

19.24% done, 318,658,810 cis-eQTLs

19.27% done, 318,707,428 cis-eQTLs

19.30% done, 318,795,103 cis-eQTLs

19.30% done, 318,795,274 cis-eQTLs

19.34% done, 318,829,189 cis-eQTLs

19.34% done, 319,180,675 cis-eQTLs

19.37% done, 319,180,803 cis-eQTLs

19.37% done, 319,641,558 cis-eQTLs

19.41% done, 320,025,700 cis-eQTLs

19.44% done, 320,547,635 cis-eQTLs

19.47% done, 321,077,417 cis-eQTLs

19.51% done, 321,364,645 cis-eQTLs

19.54% done, 321,407,075 cis-eQTLs

19.57% done, 321,471,494 cis-eQTLs

19.61% done, 321,595,267 cis-eQTLs

19.64% done, 321,870,729 cis-eQTLs

19.67% done, 322,049,128 cis-eQTLs

19.71% done, 322,425,068 cis-eQTLs

19.74% done, 322,851,286 cis-eQTLs

19.77% done, 323,051,308 cis-eQTLs

19.81% done, 323,151,204 cis-eQTLs

19.81% done, 323,179,897 cis-eQTLs

19.84% done, 323,187,435 cis-eQTLs

19.84% done, 323,675,184 cis-eQTLs

19.87% done, 324,358,212 cis-eQTLs

19.91% done, 325,058,542 cis-eQTLs

19.94% done, 325,542,001 cis-eQTLs

19.98% done, 325,771,079 cis-eQTLs

20.01% done, 325,921,457 cis-eQTLs

20.04% done, 326,099,400 cis-eQTLs

20.08% done, 326,354,312 cis-eQTLs

20.11% done, 327,047,738 cis-eQTLs

20.11% done, 327,077,891 cis-eQTLs

20.14% done, 327,172,065 cis-eQTLs

20.14% done, 327,505,439 cis-eQTLs

20.18% done, 327,955,306 cis-eQTLs

20.21% done, 328,756,546 cis-eQTLs

20.24% done, 329,558,809 cis-eQTLs

20.28% done, 330,234,764 cis-eQTLs

20.31% done, 330,924,505 cis-eQTLs

20.34% done, 331,517,860 cis-eQTLs

20.34% done, 331,740,506 cis-eQTLs

20.38% done, 331,971,871 cis-eQTLs

20.38% done, 332,783,711 cis-eQTLs

20.41% done, 333,918,147 cis-eQTLs

20.44% done, 335,146,085 cis-eQTLs

20.44% done, 335,156,910 cis-eQTLs

20.48% done, 335,465,426 cis-eQTLs

20.48% done, 335,750,499 cis-eQTLs

20.51% done, 336,124,926 cis-eQTLs

20.55% done, 336,415,435 cis-eQTLs

20.58% done, 336,800,173 cis-eQTLs

20.61% done, 337,442,456 cis-eQTLs

20.65% done, 338,187,971 cis-eQTLs

20.68% done, 338,436,344 cis-eQTLs

20.71% done, 338,816,555 cis-eQTLs

20.75% done, 339,296,095 cis-eQTLs

20.75% done, 339,310,436 cis-eQTLs

20.78% done, 339,420,453 cis-eQTLs

20.78% done, 340,014,867 cis-eQTLs

20.81% done, 340,352,456 cis-eQTLs

20.85% done, 340,929,753 cis-eQTLs

20.88% done, 341,517,234 cis-eQTLs

20.91% done, 342,053,091 cis-eQTLs

20.95% done, 342,236,397 cis-eQTLs

20.98% done, 342,273,480 cis-eQTLs

21.01% done, 342,463,186 cis-eQTLs

21.05% done, 342,774,794 cis-eQTLs

21.08% done, 343,215,346 cis-eQTLs

21.11% done, 343,281,829 cis-eQTLs

21.11% done, 343,544,156 cis-eQTLs

21.15% done, 343,544,820 cis-eQTLs

21.15% done, 344,334,184 cis-eQTLs

21.18% done, 345,019,000 cis-eQTLs

21.22% done, 345,529,094 cis-eQTLs

21.25% done, 345,955,457 cis-eQTLs

21.28% done, 346,231,344 cis-eQTLs

21.32% done, 346,499,906 cis-eQTLs

21.35% done, 346,827,526 cis-eQTLs

21.38% done, 347,284,534 cis-eQTLs

21.38% done, 347,343,191 cis-eQTLs

21.42% done, 347,457,019 cis-eQTLs

21.42% done, 347,945,843 cis-eQTLs

21.45% done, 348,351,976 cis-eQTLs

21.48% done, 348,733,516 cis-eQTLs

21.52% done, 349,226,617 cis-eQTLs

21.55% done, 349,550,048 cis-eQTLs

21.58% done, 349,601,181 cis-eQTLs

21.62% done, 349,643,810 cis-eQTLs

21.65% done, 349,696,900 cis-eQTLs

21.68% done, 349,735,966 cis-eQTLs

21.72% done, 349,803,798 cis-eQTLs

21.75% done, 349,889,010 cis-eQTLs

21.79% done, 349,964,084 cis-eQTLs

21.82% done, 350,216,070 cis-eQTLs

21.85% done, 350,521,851 cis-eQTLs

21.89% done, 351,124,609 cis-eQTLs

21.89% done, 351,173,586 cis-eQTLs

21.92% done, 351,284,320 cis-eQTLs

21.92% done, 351,784,021 cis-eQTLs

21.95% done, 352,392,289 cis-eQTLs

21.99% done, 352,937,599 cis-eQTLs

22.02% done, 353,131,798 cis-eQTLs

22.05% done, 353,261,498 cis-eQTLs

22.09% done, 353,406,308 cis-eQTLs

22.12% done, 353,518,059 cis-eQTLs

22.15% done, 353,822,809 cis-eQTLs

22.19% done, 354,209,163 cis-eQTLs

22.22% done, 354,590,331 cis-eQTLs

22.25% done, 355,096,283 cis-eQTLs

22.29% done, 355,300,645 cis-eQTLs

22.29% done, 355,445,853 cis-eQTLs

22.32% done, 355,449,089 cis-eQTLs

22.32% done, 356,006,757 cis-eQTLs

22.36% done, 357,150,777 cis-eQTLs

22.39% done, 358,554,889 cis-eQTLs

22.42% done, 359,201,696 cis-eQTLs

22.42% done, 359,287,462 cis-eQTLs

22.46% done, 359,386,163 cis-eQTLs

22.46% done, 360,175,700 cis-eQTLs

22.49% done, 360,884,830 cis-eQTLs

22.52% done, 361,548,523 cis-eQTLs

22.56% done, 361,976,085 cis-eQTLs

22.59% done, 362,500,778 cis-eQTLs

22.62% done, 362,936,700 cis-eQTLs

22.66% done, 363,221,265 cis-eQTLs

22.69% done, 363,476,962 cis-eQTLs

22.72% done, 363,876,418 cis-eQTLs

22.76% done, 364,245,020 cis-eQTLs

22.76% done, 364,673,255 cis-eQTLs

22.79% done, 364,714,303 cis-eQTLs

22.79% done, 365,925,993 cis-eQTLs

22.82% done, 367,010,541 cis-eQTLs

22.86% done, 368,118,140 cis-eQTLs

22.89% done, 369,321,244 cis-eQTLs

22.93% done, 370,060,876 cis-eQTLs

22.93% done, 370,319,368 cis-eQTLs

22.96% done, 370,401,685 cis-eQTLs

22.96% done, 371,195,662 cis-eQTLs

22.99% done, 373,856,466 cis-eQTLs

22.99% done, 373,992,239 cis-eQTLs

23.03% done, 374,952,802 cis-eQTLs

23.03% done, 376,315,200 cis-eQTLs

23.06% done, 377,907,389 cis-eQTLs

23.06% done, 377,926,276 cis-eQTLs

23.09% done, 379,056,328 cis-eQTLs

23.09% done, 379,465,910 cis-eQTLs

23.13% done, 379,677,961 cis-eQTLs

23.13% done, 380,439,678 cis-eQTLs

23.16% done, 381,227,633 cis-eQTLs

23.19% done, 381,805,635 cis-eQTLs

23.23% done, 382,685,142 cis-eQTLs

23.26% done, 384,142,741 cis-eQTLs

23.29% done, 385,420,577 cis-eQTLs

23.29% done, 385,652,241 cis-eQTLs

23.33% done, 386,227,099 cis-eQTLs

23.33% done, 387,221,528 cis-eQTLs

23.36% done, 387,258,496 cis-eQTLs

23.36% done, 388,882,164 cis-eQTLs

23.39% done, 389,457,565 cis-eQTLs

23.43% done, 389,741,306 cis-eQTLs

23.46% done, 390,250,875 cis-eQTLs

23.50% done, 390,540,444 cis-eQTLs

23.53% done, 390,796,914 cis-eQTLs

23.56% done, 390,918,151 cis-eQTLs

23.60% done, 391,172,941 cis-eQTLs

23.63% done, 391,516,647 cis-eQTLs

23.66% done, 391,775,216 cis-eQTLs

23.70% done, 392,063,344 cis-eQTLs

23.70% done, 392,328,397 cis-eQTLs

23.73% done, 392,335,484 cis-eQTLs

23.73% done, 392,781,310 cis-eQTLs

23.76% done, 393,185,132 cis-eQTLs

23.80% done, 393,389,677 cis-eQTLs

23.83% done, 393,456,301 cis-eQTLs

23.86% done, 393,591,886 cis-eQTLs

23.90% done, 393,820,232 cis-eQTLs

23.93% done, 393,970,199 cis-eQTLs

23.96% done, 394,165,901 cis-eQTLs

24.00% done, 394,347,676 cis-eQTLs

24.03% done, 394,693,283 cis-eQTLs

24.06% done, 395,293,158 cis-eQTLs

24.10% done, 395,885,654 cis-eQTLs

24.13% done, 396,165,091 cis-eQTLs

24.17% done, 396,235,995 cis-eQTLs

24.20% done, 396,309,468 cis-eQTLs

24.23% done, 396,349,492 cis-eQTLs

24.27% done, 396,419,020 cis-eQTLs

24.27% done, 396,437,714 cis-eQTLs

24.30% done, 396,471,476 cis-eQTLs

24.30% done, 396,540,514 cis-eQTLs

24.33% done, 396,588,598 cis-eQTLs

24.37% done, 396,632,117 cis-eQTLs

24.40% done, 396,692,371 cis-eQTLs

24.43% done, 396,731,419 cis-eQTLs

24.47% done, 396,775,112 cis-eQTLs

24.50% done, 396,977,679 cis-eQTLs

24.53% done, 397,145,612 cis-eQTLs

24.57% done, 397,560,167 cis-eQTLs

24.60% done, 398,224,699 cis-eQTLs

24.63% done, 398,952,990 cis-eQTLs

24.67% done, 399,656,050 cis-eQTLs

24.70% done, 400,416,089 cis-eQTLs

24.74% done, 401,128,873 cis-eQTLs

24.77% done, 401,426,785 cis-eQTLs

24.77% done, 401,627,470 cis-eQTLs

24.80% done, 401,630,926 cis-eQTLs

24.80% done, 401,791,862 cis-eQTLs

24.84% done, 401,875,785 cis-eQTLs

24.87% done, 402,001,526 cis-eQTLs

24.90% done, 402,070,664 cis-eQTLs

24.94% done, 402,335,893 cis-eQTLs

24.97% done, 402,846,652 cis-eQTLs

25.00% done, 403,166,961 cis-eQTLs

25.04% done, 403,495,427 cis-eQTLs

25.07% done, 404,018,313 cis-eQTLs

25.10% done, 404,530,573 cis-eQTLs

25.14% done, 405,032,835 cis-eQTLs

25.17% done, 405,478,995 cis-eQTLs

25.17% done, 405,628,148 cis-eQTLs

25.20% done, 405,709,688 cis-eQTLs

25.20% done, 406,328,614 cis-eQTLs

25.24% done, 406,617,162 cis-eQTLs

25.27% done, 406,661,069 cis-eQTLs

25.31% done, 406,701,649 cis-eQTLs

25.34% done, 406,736,244 cis-eQTLs

25.37% done, 406,770,737 cis-eQTLs

25.41% done, 406,866,618 cis-eQTLs

25.44% done, 406,962,329 cis-eQTLs

25.47% done, 406,998,255 cis-eQTLs

25.51% done, 407,032,281 cis-eQTLs

25.54% done, 407,085,177 cis-eQTLs

25.57% done, 407,175,155 cis-eQTLs

25.61% done, 407,278,663 cis-eQTLs

25.64% done, 407,349,701 cis-eQTLs

25.67% done, 407,621,155 cis-eQTLs

25.71% done, 407,857,145 cis-eQTLs

25.74% done, 407,961,134 cis-eQTLs

25.77% done, 408,117,747 cis-eQTLs

25.81% done, 408,481,543 cis-eQTLs

25.84% done, 408,838,385 cis-eQTLs

25.87% done, 409,042,040 cis-eQTLs

25.91% done, 409,490,086 cis-eQTLs

25.94% done, 409,795,498 cis-eQTLs

25.94% done, 409,799,580 cis-eQTLs

25.98% done, 410,047,635 cis-eQTLs

25.98% done, 410,318,009 cis-eQTLs

26.01% done, 410,354,510 cis-eQTLs

26.01% done, 411,092,506 cis-eQTLs

26.04% done, 411,713,272 cis-eQTLs

26.08% done, 412,109,546 cis-eQTLs

26.11% done, 412,492,101 cis-eQTLs

26.14% done, 412,864,488 cis-eQTLs

26.18% done, 413,177,582 cis-eQTLs

26.21% done, 413,468,847 cis-eQTLs

26.24% done, 414,180,487 cis-eQTLs

26.28% done, 414,594,593 cis-eQTLs

26.28% done, 414,615,488 cis-eQTLs

26.31% done, 414,671,295 cis-eQTLs

26.31% done, 414,897,504 cis-eQTLs

26.34% done, 415,171,323 cis-eQTLs

26.38% done, 415,700,599 cis-eQTLs

26.41% done, 416,261,431 cis-eQTLs

26.44% done, 416,791,931 cis-eQTLs

26.48% done, 417,086,173 cis-eQTLs

26.51% done, 417,195,806 cis-eQTLs

26.55% done, 417,258,009 cis-eQTLs

26.58% done, 417,360,900 cis-eQTLs

26.61% done, 417,612,562 cis-eQTLs

26.65% done, 417,919,208 cis-eQTLs

26.68% done, 418,132,851 cis-eQTLs

26.71% done, 418,200,753 cis-eQTLs

26.75% done, 418,261,532 cis-eQTLs

26.78% done, 418,554,523 cis-eQTLs

26.78% done, 418,560,336 cis-eQTLs

26.81% done, 418,819,856 cis-eQTLs

26.81% done, 419,033,840 cis-eQTLs

26.85% done, 419,036,773 cis-eQTLs

26.85% done, 419,394,711 cis-eQTLs

26.88% done, 419,638,331 cis-eQTLs

26.91% done, 419,902,516 cis-eQTLs

26.95% done, 420,325,232 cis-eQTLs

26.98% done, 420,466,960 cis-eQTLs

27.01% done, 420,778,583 cis-eQTLs

27.05% done, 421,090,474 cis-eQTLs

27.08% done, 421,340,784 cis-eQTLs

27.11% done, 421,763,930 cis-eQTLs

27.15% done, 422,167,628 cis-eQTLs

27.18% done, 422,708,415 cis-eQTLs

27.18% done, 422,708,942 cis-eQTLs

27.22% done, 422,832,952 cis-eQTLs

27.22% done, 422,877,986 cis-eQTLs

27.25% done, 423,348,507 cis-eQTLs

27.28% done, 423,735,312 cis-eQTLs

27.32% done, 423,955,231 cis-eQTLs

27.35% done, 424,022,270 cis-eQTLs

27.38% done, 424,083,673 cis-eQTLs

27.42% done, 424,188,865 cis-eQTLs

27.45% done, 424,288,160 cis-eQTLs

27.48% done, 424,638,322 cis-eQTLs

27.52% done, 425,047,495 cis-eQTLs

27.55% done, 425,254,187 cis-eQTLs

27.58% done, 425,524,576 cis-eQTLs

27.62% done, 426,034,303 cis-eQTLs

27.65% done, 426,473,551 cis-eQTLs

27.68% done, 426,842,614 cis-eQTLs

27.72% done, 427,020,617 cis-eQTLs

27.75% done, 427,182,304 cis-eQTLs

27.79% done, 427,246,635 cis-eQTLs

27.82% done, 427,336,566 cis-eQTLs

27.82% done, 427,367,538 cis-eQTLs

27.85% done, 427,371,644 cis-eQTLs

27.85% done, 427,802,982 cis-eQTLs

27.89% done, 427,968,807 cis-eQTLs

27.92% done, 428,021,356 cis-eQTLs

27.95% done, 428,054,632 cis-eQTLs

27.99% done, 428,117,046 cis-eQTLs

28.02% done, 428,214,451 cis-eQTLs

28.05% done, 428,304,456 cis-eQTLs

28.09% done, 428,385,068 cis-eQTLs

28.12% done, 428,450,657 cis-eQTLs

28.15% done, 428,533,233 cis-eQTLs

28.19% done, 428,658,831 cis-eQTLs

28.22% done, 428,897,203 cis-eQTLs

28.25% done, 429,380,850 cis-eQTLs

28.29% done, 430,117,530 cis-eQTLs

28.32% done, 430,630,565 cis-eQTLs

28.36% done, 430,887,996 cis-eQTLs

28.39% done, 431,106,343 cis-eQTLs

28.39% done, 431,113,769 cis-eQTLs

28.42% done, 431,277,001 cis-eQTLs

28.42% done, 431,412,497 cis-eQTLs

28.46% done, 431,413,198 cis-eQTLs

28.46% done, 431,673,120 cis-eQTLs

28.49% done, 432,200,731 cis-eQTLs

28.52% done, 432,563,227 cis-eQTLs

28.56% done, 432,843,649 cis-eQTLs

28.59% done, 433,001,892 cis-eQTLs

28.62% done, 433,402,938 cis-eQTLs

28.66% done, 433,898,882 cis-eQTLs

28.69% done, 434,555,271 cis-eQTLs

28.69% done, 434,627,344 cis-eQTLs

28.72% done, 434,748,564 cis-eQTLs

28.72% done, 435,088,725 cis-eQTLs

28.76% done, 435,463,604 cis-eQTLs

28.79% done, 435,744,071 cis-eQTLs

28.82% done, 436,008,134 cis-eQTLs

28.86% done, 436,228,029 cis-eQTLs

28.89% done, 436,646,247 cis-eQTLs

28.92% done, 436,864,781 cis-eQTLs

28.96% done, 436,907,186 cis-eQTLs

28.99% done, 436,957,669 cis-eQTLs

29.03% done, 437,030,266 cis-eQTLs

29.06% done, 437,108,450 cis-eQTLs

29.09% done, 437,381,548 cis-eQTLs

29.13% done, 437,561,108 cis-eQTLs

29.16% done, 437,935,386 cis-eQTLs

29.19% done, 438,385,607 cis-eQTLs

29.23% done, 438,508,537 cis-eQTLs

29.26% done, 438,602,458 cis-eQTLs

29.29% done, 438,896,419 cis-eQTLs

29.29% done, 438,896,771 cis-eQTLs

29.33% done, 439,249,424 cis-eQTLs

29.33% done, 439,483,877 cis-eQTLs

29.36% done, 439,862,542 cis-eQTLs

29.39% done, 439,930,996 cis-eQTLs

29.43% done, 440,022,873 cis-eQTLs

29.46% done, 440,561,193 cis-eQTLs

29.49% done, 440,955,176 cis-eQTLs

29.53% done, 441,181,727 cis-eQTLs

29.56% done, 441,530,031 cis-eQTLs

29.60% done, 441,815,392 cis-eQTLs

29.63% done, 442,033,682 cis-eQTLs

29.66% done, 442,086,729 cis-eQTLs

29.70% done, 442,134,065 cis-eQTLs

29.73% done, 442,205,956 cis-eQTLs

29.76% done, 442,282,433 cis-eQTLs

29.80% done, 442,403,152 cis-eQTLs

29.83% done, 442,641,753 cis-eQTLs

29.86% done, 443,175,489 cis-eQTLs

29.90% done, 443,763,651 cis-eQTLs

29.90% done, 443,958,814 cis-eQTLs

29.93% done, 444,125,155 cis-eQTLs

29.93% done, 444,796,418 cis-eQTLs

29.96% done, 445,826,562 cis-eQTLs

30.00% done, 446,886,621 cis-eQTLs

30.03% done, 447,769,248 cis-eQTLs

30.06% done, 448,622,369 cis-eQTLs

30.10% done, 449,120,899 cis-eQTLs

30.13% done, 449,501,504 cis-eQTLs

30.17% done, 449,890,556 cis-eQTLs

30.20% done, 450,108,391 cis-eQTLs

30.20% done, 450,140,196 cis-eQTLs

30.23% done, 450,237,283 cis-eQTLs

30.23% done, 450,407,295 cis-eQTLs

30.27% done, 450,411,336 cis-eQTLs

30.27% done, 450,917,952 cis-eQTLs

30.30% done, 452,783,945 cis-eQTLs

30.33% done, 455,174,909 cis-eQTLs

30.33% done, 455,409,384 cis-eQTLs

30.37% done, 456,419,689 cis-eQTLs

30.37% done, 457,712,876 cis-eQTLs

30.40% done, 457,725,790 cis-eQTLs

30.40% done, 459,076,646 cis-eQTLs

30.43% done, 459,872,704 cis-eQTLs

30.47% done, 460,595,894 cis-eQTLs

30.50% done, 461,066,289 cis-eQTLs

30.53% done, 461,506,732 cis-eQTLs

30.57% done, 461,914,163 cis-eQTLs

30.60% done, 462,498,470 cis-eQTLs

30.60% done, 462,565,757 cis-eQTLs

30.63% done, 462,858,954 cis-eQTLs

30.63% done, 463,096,346 cis-eQTLs

30.67% done, 463,475,117 cis-eQTLs

30.70% done, 463,703,472 cis-eQTLs

30.74% done, 463,998,410 cis-eQTLs

30.77% done, 464,564,852 cis-eQTLs

30.80% done, 465,216,321 cis-eQTLs

30.84% done, 465,391,225 cis-eQTLs

30.87% done, 465,504,027 cis-eQTLs

30.90% done, 465,959,131 cis-eQTLs

30.94% done, 466,678,781 cis-eQTLs

30.97% done, 467,074,877 cis-eQTLs

30.97% done, 467,089,485 cis-eQTLs

31.00% done, 467,373,119 cis-eQTLs

31.00% done, 467,724,722 cis-eQTLs

31.04% done, 467,724,749 cis-eQTLs

31.04% done, 467,870,072 cis-eQTLs

31.07% done, 467,920,836 cis-eQTLs

31.10% done, 468,002,560 cis-eQTLs

31.14% done, 468,109,221 cis-eQTLs

31.17% done, 468,192,894 cis-eQTLs

31.20% done, 468,277,047 cis-eQTLs

31.24% done, 468,381,141 cis-eQTLs

31.27% done, 468,513,442 cis-eQTLs

31.30% done, 468,602,472 cis-eQTLs

31.34% done, 468,662,942 cis-eQTLs

31.37% done, 468,750,671 cis-eQTLs

31.41% done, 468,824,839 cis-eQTLs

31.44% done, 468,911,250 cis-eQTLs

31.47% done, 468,991,949 cis-eQTLs

31.51% done, 469,044,408 cis-eQTLs

31.54% done, 469,231,026 cis-eQTLs

31.57% done, 469,862,799 cis-eQTLs

31.61% done, 470,411,867 cis-eQTLs

31.64% done, 470,846,555 cis-eQTLs

31.67% done, 471,332,070 cis-eQTLs

31.71% done, 471,800,069 cis-eQTLs

31.71% done, 471,848,573 cis-eQTLs

31.74% done, 471,912,370 cis-eQTLs

31.74% done, 472,348,064 cis-eQTLs

31.77% done, 472,801,636 cis-eQTLs

31.81% done, 473,404,064 cis-eQTLs

31.84% done, 473,847,870 cis-eQTLs

31.87% done, 474,166,043 cis-eQTLs

31.91% done, 474,595,738 cis-eQTLs

31.94% done, 474,910,780 cis-eQTLs

31.98% done, 475,590,475 cis-eQTLs

32.01% done, 475,831,709 cis-eQTLs

32.01% done, 475,848,853 cis-eQTLs

32.04% done, 475,863,872 cis-eQTLs

32.04% done, 475,938,283 cis-eQTLs

32.08% done, 476,018,011 cis-eQTLs

32.11% done, 476,288,209 cis-eQTLs

32.14% done, 476,424,350 cis-eQTLs

32.18% done, 476,832,211 cis-eQTLs

32.21% done, 477,194,304 cis-eQTLs

32.24% done, 477,626,761 cis-eQTLs

32.28% done, 478,308,365 cis-eQTLs

32.31% done, 478,952,579 cis-eQTLs

32.34% done, 479,437,285 cis-eQTLs

32.38% done, 479,773,522 cis-eQTLs

32.41% done, 480,170,493 cis-eQTLs

32.44% done, 480,404,294 cis-eQTLs

32.44% done, 480,534,058 cis-eQTLs

32.48% done, 480,535,382 cis-eQTLs

32.48% done, 480,948,360 cis-eQTLs

32.51% done, 481,278,969 cis-eQTLs

32.55% done, 481,372,761 cis-eQTLs

32.58% done, 481,535,605 cis-eQTLs

32.61% done, 481,931,273 cis-eQTLs

32.65% done, 482,348,334 cis-eQTLs

32.68% done, 482,734,711 cis-eQTLs

32.71% done, 483,126,991 cis-eQTLs

32.75% done, 483,604,003 cis-eQTLs

32.78% done, 483,925,796 cis-eQTLs

32.78% done, 484,069,265 cis-eQTLs

32.81% done, 484,101,026 cis-eQTLs

32.81% done, 484,837,562 cis-eQTLs

32.85% done, 485,404,708 cis-eQTLs

32.88% done, 485,934,165 cis-eQTLs

32.91% done, 486,342,294 cis-eQTLs

32.95% done, 486,965,335 cis-eQTLs

32.98% done, 487,571,403 cis-eQTLs

33.01% done, 488,078,453 cis-eQTLs

33.01% done, 488,168,488 cis-eQTLs

33.05% done, 488,255,474 cis-eQTLs

33.05% done, 488,679,077 cis-eQTLs

33.08% done, 489,198,875 cis-eQTLs

33.11% done, 489,649,930 cis-eQTLs

33.15% done, 489,992,618 cis-eQTLs

33.18% done, 490,315,058 cis-eQTLs

33.22% done, 490,501,223 cis-eQTLs

33.25% done, 490,550,907 cis-eQTLs

33.28% done, 490,598,236 cis-eQTLs

33.32% done, 490,805,529 cis-eQTLs

33.35% done, 491,231,855 cis-eQTLs

33.38% done, 491,502,380 cis-eQTLs

33.38% done, 491,502,499 cis-eQTLs

33.42% done, 491,666,926 cis-eQTLs

33.42% done, 491,763,419 cis-eQTLs

33.45% done, 492,017,337 cis-eQTLs

33.48% done, 492,345,761 cis-eQTLs

33.52% done, 493,018,638 cis-eQTLs

33.55% done, 493,582,302 cis-eQTLs

33.58% done, 493,703,586 cis-eQTLs

33.62% done, 493,942,593 cis-eQTLs

33.65% done, 494,035,825 cis-eQTLs

33.68% done, 494,184,513 cis-eQTLs

33.72% done, 494,270,901 cis-eQTLs

33.75% done, 494,484,182 cis-eQTLs

33.79% done, 494,745,818 cis-eQTLs

33.82% done, 494,818,554 cis-eQTLs

33.85% done, 494,881,261 cis-eQTLs

33.89% done, 494,948,786 cis-eQTLs

33.92% done, 495,147,014 cis-eQTLs

33.92% done, 495,251,671 cis-eQTLs

33.95% done, 495,284,864 cis-eQTLs

33.95% done, 495,501,328 cis-eQTLs

33.99% done, 495,757,310 cis-eQTLs

34.02% done, 496,004,769 cis-eQTLs

34.05% done, 496,400,026 cis-eQTLs

34.09% done, 496,864,900 cis-eQTLs

34.12% done, 497,465,746 cis-eQTLs

34.15% done, 497,828,807 cis-eQTLs

34.19% done, 498,014,153 cis-eQTLs

34.22% done, 498,454,919 cis-eQTLs

34.25% done, 499,064,175 cis-eQTLs

34.29% done, 499,451,249 cis-eQTLs

34.32% done, 499,524,834 cis-eQTLs

34.36% done, 499,634,871 cis-eQTLs

34.39% done, 499,848,973 cis-eQTLs

34.39% done, 500,006,752 cis-eQTLs

34.42% done, 500,011,104 cis-eQTLs

34.42% done, 500,195,085 cis-eQTLs

34.46% done, 500,328,482 cis-eQTLs

34.49% done, 500,537,053 cis-eQTLs

34.52% done, 501,075,079 cis-eQTLs

34.56% done, 501,459,360 cis-eQTLs

34.59% done, 501,871,831 cis-eQTLs

34.62% done, 502,248,363 cis-eQTLs

34.66% done, 502,529,811 cis-eQTLs

34.69% done, 503,103,971 cis-eQTLs

34.72% done, 503,433,625 cis-eQTLs

34.76% done, 503,648,112 cis-eQTLs

34.79% done, 503,832,274 cis-eQTLs

34.82% done, 504,002,151 cis-eQTLs

34.82% done, 504,155,158 cis-eQTLs

34.86% done, 504,155,229 cis-eQTLs

34.86% done, 505,335,720 cis-eQTLs

34.89% done, 506,060,496 cis-eQTLs

34.92% done, 507,059,231 cis-eQTLs

34.92% done, 507,120,928 cis-eQTLs

34.96% done, 507,387,027 cis-eQTLs

34.96% done, 508,031,741 cis-eQTLs

34.99% done, 508,322,882 cis-eQTLs

35.03% done, 509,151,181 cis-eQTLs

35.06% done, 509,975,001 cis-eQTLs

35.06% done, 510,488,639 cis-eQTLs

35.09% done, 510,494,683 cis-eQTLs

35.09% done, 512,346,554 cis-eQTLs

35.13% done, 513,221,748 cis-eQTLs

35.13% done, 513,232,712 cis-eQTLs

35.16% done, 513,458,662 cis-eQTLs

35.16% done, 513,770,003 cis-eQTLs

35.19% done, 513,899,800 cis-eQTLs

35.23% done, 514,244,880 cis-eQTLs

35.26% done, 514,767,320 cis-eQTLs

35.29% done, 515,224,909 cis-eQTLs

35.33% done, 515,884,589 cis-eQTLs

35.36% done, 516,971,417 cis-eQTLs

35.36% done, 517,015,051 cis-eQTLs

35.39% done, 517,331,131 cis-eQTLs

35.39% done, 518,188,346 cis-eQTLs

35.43% done, 518,933,837 cis-eQTLs

35.46% done, 519,100,280 cis-eQTLs

35.49% done, 519,270,307 cis-eQTLs

35.53% done, 519,854,796 cis-eQTLs

35.56% done, 520,357,806 cis-eQTLs

35.60% done, 520,476,132 cis-eQTLs

35.63% done, 521,078,732 cis-eQTLs

35.66% done, 521,688,148 cis-eQTLs

35.66% done, 521,688,802 cis-eQTLs

35.70% done, 521,816,634 cis-eQTLs

35.70% done, 522,136,999 cis-eQTLs

35.73% done, 522,763,630 cis-eQTLs

35.76% done, 523,281,014 cis-eQTLs

35.80% done, 523,485,044 cis-eQTLs

35.83% done, 523,583,734 cis-eQTLs

35.86% done, 523,874,584 cis-eQTLs

35.90% done, 524,080,553 cis-eQTLs

35.93% done, 524,170,301 cis-eQTLs

35.96% done, 524,260,958 cis-eQTLs

36.00% done, 524,527,268 cis-eQTLs

36.03% done, 525,146,010 cis-eQTLs

36.06% done, 525,626,187 cis-eQTLs

36.10% done, 525,993,274 cis-eQTLs

36.10% done, 526,263,368 cis-eQTLs

36.13% done, 526,298,220 cis-eQTLs

36.13% done, 526,834,119 cis-eQTLs

36.17% done, 527,787,571 cis-eQTLs

36.20% done, 529,075,430 cis-eQTLs

36.23% done, 530,022,045 cis-eQTLs

36.27% done, 530,584,050 cis-eQTLs

36.27% done, 530,593,542 cis-eQTLs

36.30% done, 530,730,954 cis-eQTLs

36.30% done, 531,058,664 cis-eQTLs

36.33% done, 532,235,788 cis-eQTLs

36.37% done, 533,462,879 cis-eQTLs

36.40% done, 534,288,422 cis-eQTLs

36.40% done, 534,576,132 cis-eQTLs

36.43% done, 534,801,171 cis-eQTLs

36.43% done, 535,793,983 cis-eQTLs

36.47% done, 537,212,819 cis-eQTLs

36.50% done, 538,432,559 cis-eQTLs

36.53% done, 539,247,624 cis-eQTLs

36.53% done, 539,315,972 cis-eQTLs

36.57% done, 539,602,538 cis-eQTLs

36.57% done, 540,211,137 cis-eQTLs

36.60% done, 541,121,276 cis-eQTLs

36.63% done, 541,972,009 cis-eQTLs

36.67% done, 543,229,414 cis-eQTLs

36.70% done, 544,081,467 cis-eQTLs

36.74% done, 544,728,939 cis-eQTLs

36.74% done, 544,753,079 cis-eQTLs

36.77% done, 545,063,584 cis-eQTLs

36.77% done, 545,327,439 cis-eQTLs

36.80% done, 545,847,002 cis-eQTLs

36.84% done, 546,603,789 cis-eQTLs

36.87% done, 547,385,124 cis-eQTLs

36.90% done, 547,795,273 cis-eQTLs

36.94% done, 547,943,549 cis-eQTLs

36.97% done, 548,261,541 cis-eQTLs

37.00% done, 549,183,161 cis-eQTLs

37.04% done, 549,916,063 cis-eQTLs

37.07% done, 550,320,648 cis-eQTLs

37.07% done, 550,499,892 cis-eQTLs

37.10% done, 550,507,522 cis-eQTLs

37.10% done, 551,107,896 cis-eQTLs

37.14% done, 551,778,583 cis-eQTLs

37.17% done, 552,454,577 cis-eQTLs

37.20% done, 553,122,905 cis-eQTLs

37.24% done, 553,663,380 cis-eQTLs

37.27% done, 554,174,993 cis-eQTLs

37.31% done, 554,413,893 cis-eQTLs

37.34% done, 554,567,229 cis-eQTLs

37.34% done, 554,632,381 cis-eQTLs

37.37% done, 554,684,479 cis-eQTLs

37.37% done, 555,033,578 cis-eQTLs

37.41% done, 555,443,160 cis-eQTLs

37.44% done, 555,832,263 cis-eQTLs

37.47% done, 556,040,552 cis-eQTLs

37.51% done, 556,149,123 cis-eQTLs

37.54% done, 556,598,684 cis-eQTLs

37.57% done, 557,390,151 cis-eQTLs

37.61% done, 558,330,244 cis-eQTLs

37.64% done, 559,614,181 cis-eQTLs

37.64% done, 559,688,961 cis-eQTLs

37.67% done, 559,800,341 cis-eQTLs

37.67% done, 560,732,427 cis-eQTLs

37.71% done, 562,562,180 cis-eQTLs

37.74% done, 563,852,450 cis-eQTLs

37.74% done, 564,739,408 cis-eQTLs

37.77% done, 565,080,228 cis-eQTLs

37.77% done, 568,085,666 cis-eQTLs

37.81% done, 568,338,217 cis-eQTLs

37.81% done, 571,678,608 cis-eQTLs

37.84% done, 571,767,425 cis-eQTLs

37.84% done, 575,347,280 cis-eQTLs

37.84% done, 575,360,533 cis-eQTLs

37.88% done, 578,268,174 cis-eQTLs

37.88% done, 579,855,251 cis-eQTLs

37.91% done, 580,448,499 cis-eQTLs

37.91% done, 583,613,932 cis-eQTLs

37.94% done, 586,954,042 cis-eQTLs

37.94% done, 587,583,362 cis-eQTLs

37.98% done, 590,227,942 cis-eQTLs

37.98% done, 591,881,376 cis-eQTLs

38.01% done, 594,466,954 cis-eQTLs

38.01% done, 596,543,644 cis-eQTLs

38.04% done, 598,777,838 cis-eQTLs

38.04% done, 601,540,527 cis-eQTLs

38.08% done, 602,352,438 cis-eQTLs

38.08% done, 605,732,008 cis-eQTLs

38.08% done, 607,100,773 cis-eQTLs

38.11% done, 608,374,680 cis-eQTLs

38.11% done, 611,341,918 cis-eQTLs

38.14% done, 612,000,968 cis-eQTLs

38.14% done, 615,572,799 cis-eQTLs

38.18% done, 616,083,197 cis-eQTLs

38.18% done, 619,717,701 cis-eQTLs

38.21% done, 619,806,823 cis-eQTLs

38.21% done, 623,512,377 cis-eQTLs

38.24% done, 627,021,302 cis-eQTLs

38.28% done, 630,305,416 cis-eQTLs

38.28% done, 630,313,802 cis-eQTLs

38.31% done, 633,174,413 cis-eQTLs

38.31% done, 633,513,631 cis-eQTLs

38.34% done, 635,951,492 cis-eQTLs

38.34% done, 637,138,517 cis-eQTLs

38.38% done, 639,176,334 cis-eQTLs

38.38% done, 642,063,091 cis-eQTLs

38.41% done, 642,982,958 cis-eQTLs

38.41% done, 646,436,306 cis-eQTLs

38.41% done, 646,441,881 cis-eQTLs

38.45% done, 647,554,118 cis-eQTLs

38.45% done, 648,009,681 cis-eQTLs

38.48% done, 648,951,319 cis-eQTLs

38.51% done, 650,027,946 cis-eQTLs

38.55% done, 651,056,321 cis-eQTLs

38.58% done, 651,459,160 cis-eQTLs

38.58% done, 651,650,048 cis-eQTLs

38.61% done, 651,656,699 cis-eQTLs

38.61% done, 652,215,325 cis-eQTLs

38.65% done, 652,701,096 cis-eQTLs

38.68% done, 653,500,301 cis-eQTLs

38.71% done, 654,741,528 cis-eQTLs

38.75% done, 655,589,699 cis-eQTLs

38.75% done, 656,058,961 cis-eQTLs

38.78% done, 656,058,962 cis-eQTLs

38.78% done, 657,307,766 cis-eQTLs

38.81% done, 657,771,366 cis-eQTLs

38.85% done, 658,279,973 cis-eQTLs

38.88% done, 658,851,590 cis-eQTLs

38.91% done, 659,116,665 cis-eQTLs

38.95% done, 659,223,606 cis-eQTLs

38.95% done, 659,227,623 cis-eQTLs

38.98% done, 659,364,201 cis-eQTLs

38.98% done, 659,523,091 cis-eQTLs

39.02% done, 659,816,241 cis-eQTLs

39.05% done, 660,126,254 cis-eQTLs

39.08% done, 660,808,927 cis-eQTLs

39.12% done, 661,505,059 cis-eQTLs

39.15% done, 661,835,652 cis-eQTLs

39.18% done, 662,023,022 cis-eQTLs

39.22% done, 662,243,240 cis-eQTLs

39.25% done, 662,719,714 cis-eQTLs

39.28% done, 662,972,805 cis-eQTLs

39.32% done, 663,025,218 cis-eQTLs

39.35% done, 663,052,010 cis-eQTLs

39.38% done, 663,088,848 cis-eQTLs

39.42% done, 663,148,249 cis-eQTLs

39.45% done, 663,359,977 cis-eQTLs

39.48% done, 663,414,211 cis-eQTLs

39.52% done, 663,465,017 cis-eQTLs

39.55% done, 663,518,511 cis-eQTLs

39.58% done, 663,554,850 cis-eQTLs

39.62% done, 663,594,583 cis-eQTLs

39.65% done, 663,664,898 cis-eQTLs

39.69% done, 663,777,509 cis-eQTLs

39.72% done, 663,872,450 cis-eQTLs

39.72% done, 663,879,116 cis-eQTLs

39.75% done, 663,956,235 cis-eQTLs

39.75% done, 664,128,849 cis-eQTLs

39.79% done, 664,132,714 cis-eQTLs

39.79% done, 664,517,076 cis-eQTLs

39.82% done, 664,814,486 cis-eQTLs

39.85% done, 665,104,640 cis-eQTLs

39.89% done, 665,699,604 cis-eQTLs

39.92% done, 665,894,480 cis-eQTLs

39.95% done, 666,253,698 cis-eQTLs

39.99% done, 666,374,204 cis-eQTLs

40.02% done, 666,457,748 cis-eQTLs

40.05% done, 666,550,108 cis-eQTLs

40.09% done, 666,669,221 cis-eQTLs

40.12% done, 666,998,160 cis-eQTLs

40.15% done, 667,266,363 cis-eQTLs

40.19% done, 667,348,710 cis-eQTLs

40.22% done, 667,512,989 cis-eQTLs

40.26% done, 667,805,615 cis-eQTLs

40.29% done, 668,085,356 cis-eQTLs

40.29% done, 668,177,772 cis-eQTLs

40.32% done, 668,179,282 cis-eQTLs

40.32% done, 668,447,234 cis-eQTLs

40.36% done, 668,760,032 cis-eQTLs

40.39% done, 668,847,385 cis-eQTLs

40.42% done, 669,268,419 cis-eQTLs

40.46% done, 669,680,490 cis-eQTLs

40.49% done, 670,208,139 cis-eQTLs

40.52% done, 670,836,502 cis-eQTLs

40.56% done, 671,046,266 cis-eQTLs

40.59% done, 671,122,475 cis-eQTLs

40.62% done, 671,197,395 cis-eQTLs

40.66% done, 671,283,009 cis-eQTLs

40.69% done, 671,331,078 cis-eQTLs

40.72% done, 671,457,199 cis-eQTLs

40.76% done, 671,715,120 cis-eQTLs

40.79% done, 671,900,067 cis-eQTLs

40.83% done, 672,222,304 cis-eQTLs

40.83% done, 672,436,552 cis-eQTLs

40.86% done, 672,493,041 cis-eQTLs

40.86% done, 672,914,904 cis-eQTLs

40.89% done, 673,117,001 cis-eQTLs

40.93% done, 673,169,204 cis-eQTLs

40.96% done, 673,190,105 cis-eQTLs

40.99% done, 673,233,873 cis-eQTLs

41.03% done, 673,517,989 cis-eQTLs

41.06% done, 674,105,279 cis-eQTLs

41.09% done, 674,733,021 cis-eQTLs

41.13% done, 675,397,935 cis-eQTLs

41.16% done, 676,039,628 cis-eQTLs

41.16% done, 676,141,823 cis-eQTLs

41.19% done, 676,223,114 cis-eQTLs

41.19% done, 676,664,572 cis-eQTLs

41.23% done, 677,358,233 cis-eQTLs

41.26% done, 677,842,029 cis-eQTLs

41.29% done, 678,170,746 cis-eQTLs

41.33% done, 678,361,995 cis-eQTLs

41.36% done, 678,434,402 cis-eQTLs

41.39% done, 678,981,963 cis-eQTLs

41.43% done, 679,386,219 cis-eQTLs

41.46% done, 679,679,975 cis-eQTLs

41.46% done, 679,692,713 cis-eQTLs

41.50% done, 679,844,860 cis-eQTLs

41.50% done, 679,991,990 cis-eQTLs

41.53% done, 680,042,786 cis-eQTLs

41.56% done, 680,158,460 cis-eQTLs

41.60% done, 680,401,027 cis-eQTLs

41.63% done, 680,716,423 cis-eQTLs

41.66% done, 680,852,322 cis-eQTLs

41.70% done, 681,081,554 cis-eQTLs

41.73% done, 681,511,037 cis-eQTLs

41.76% done, 681,862,392 cis-eQTLs

41.80% done, 682,124,971 cis-eQTLs

41.83% done, 682,541,405 cis-eQTLs

41.86% done, 682,931,654 cis-eQTLs

41.90% done, 683,328,112 cis-eQTLs

41.93% done, 683,678,072 cis-eQTLs

41.93% done, 683,833,477 cis-eQTLs

41.96% done, 683,861,036 cis-eQTLs

41.96% done, 684,326,531 cis-eQTLs

42.00% done, 684,948,959 cis-eQTLs

42.03% done, 685,491,004 cis-eQTLs

42.07% done, 686,151,525 cis-eQTLs

42.10% done, 686,884,524 cis-eQTLs

42.13% done, 687,315,491 cis-eQTLs

42.13% done, 687,503,094 cis-eQTLs

42.17% done, 687,515,215 cis-eQTLs

42.17% done, 687,713,111 cis-eQTLs

42.20% done, 687,878,859 cis-eQTLs

42.23% done, 688,349,295 cis-eQTLs

42.27% done, 689,026,900 cis-eQTLs

42.30% done, 689,270,001 cis-eQTLs

42.33% done, 689,579,944 cis-eQTLs

42.37% done, 689,877,621 cis-eQTLs

42.40% done, 690,307,890 cis-eQTLs

42.43% done, 690,942,364 cis-eQTLs

42.43% done, 690,970,355 cis-eQTLs

42.47% done, 691,255,554 cis-eQTLs

42.47% done, 691,892,718 cis-eQTLs

42.50% done, 692,508,404 cis-eQTLs

42.53% done, 693,242,910 cis-eQTLs

42.57% done, 693,748,178 cis-eQTLs

42.60% done, 694,168,199 cis-eQTLs

42.64% done, 694,367,030 cis-eQTLs

42.67% done, 694,766,360 cis-eQTLs

42.70% done, 695,310,442 cis-eQTLs

42.74% done, 695,550,641 cis-eQTLs

42.77% done, 695,970,374 cis-eQTLs

42.77% done, 696,204,679 cis-eQTLs

42.80% done, 696,230,454 cis-eQTLs

42.80% done, 697,149,922 cis-eQTLs

42.84% done, 698,084,314 cis-eQTLs

42.87% done, 698,829,478 cis-eQTLs

42.90% done, 699,563,956 cis-eQTLs

42.94% done, 700,073,397 cis-eQTLs

42.97% done, 700,425,254 cis-eQTLs

43.00% done, 700,604,190 cis-eQTLs

43.04% done, 700,976,559 cis-eQTLs

43.04% done, 700,977,473 cis-eQTLs

43.07% done, 701,361,838 cis-eQTLs

43.07% done, 701,532,945 cis-eQTLs

43.10% done, 701,555,641 cis-eQTLs

43.10% done, 701,753,728 cis-eQTLs

43.14% done, 701,942,963 cis-eQTLs

43.17% done, 702,692,707 cis-eQTLs

43.21% done, 703,987,589 cis-eQTLs

43.24% done, 705,106,955 cis-eQTLs

43.27% done, 706,258,045 cis-eQTLs

43.27% done, 706,284,941 cis-eQTLs

43.31% done, 707,470,896 cis-eQTLs

43.31% done, 708,041,414 cis-eQTLs

43.34% done, 708,268,904 cis-eQTLs

43.34% done, 709,425,759 cis-eQTLs

43.37% done, 710,674,720 cis-eQTLs

43.41% done, 712,173,465 cis-eQTLs

43.44% done, 713,044,171 cis-eQTLs

43.44% done, 713,312,516 cis-eQTLs

43.47% done, 713,898,824 cis-eQTLs

43.47% done, 716,125,817 cis-eQTLs

43.51% done, 716,145,452 cis-eQTLs

43.51% done, 719,135,928 cis-eQTLs

43.51% done, 719,482,581 cis-eQTLs

43.54% done, 720,168,970 cis-eQTLs

43.54% done, 722,465,769 cis-eQTLs

43.57% done, 724,371,833 cis-eQTLs

43.61% done, 725,099,144 cis-eQTLs

43.64% done, 725,502,003 cis-eQTLs

43.64% done, 725,896,562 cis-eQTLs

43.67% done, 726,035,985 cis-eQTLs

43.67% done, 727,343,299 cis-eQTLs

43.71% done, 729,022,143 cis-eQTLs

43.74% done, 730,246,462 cis-eQTLs

43.78% done, 731,076,719 cis-eQTLs

43.81% done, 731,399,604 cis-eQTLs

43.81% done, 731,536,725 cis-eQTLs

43.84% done, 731,612,710 cis-eQTLs

43.84% done, 732,041,601 cis-eQTLs

43.88% done, 732,283,667 cis-eQTLs

43.91% done, 732,341,032 cis-eQTLs

43.94% done, 732,392,992 cis-eQTLs

43.98% done, 732,468,059 cis-eQTLs

44.01% done, 732,662,670 cis-eQTLs

44.04% done, 732,875,209 cis-eQTLs

44.08% done, 733,210,615 cis-eQTLs

44.11% done, 733,610,176 cis-eQTLs

44.14% done, 733,804,309 cis-eQTLs

44.18% done, 733,990,938 cis-eQTLs

44.21% done, 734,150,411 cis-eQTLs

44.24% done, 734,313,040 cis-eQTLs

44.28% done, 734,651,975 cis-eQTLs

44.31% done, 735,144,890 cis-eQTLs

44.34% done, 735,530,007 cis-eQTLs

44.38% done, 735,890,534 cis-eQTLs

44.41% done, 736,199,195 cis-eQTLs

44.45% done, 736,636,533 cis-eQTLs

44.48% done, 736,972,930 cis-eQTLs

44.48% done, 736,973,380 cis-eQTLs

44.51% done, 737,134,486 cis-eQTLs

44.51% done, 737,337,762 cis-eQTLs

44.55% done, 737,354,851 cis-eQTLs

44.55% done, 737,911,552 cis-eQTLs

44.58% done, 738,606,286 cis-eQTLs

44.61% done, 739,005,336 cis-eQTLs

44.65% done, 739,566,029 cis-eQTLs

44.68% done, 740,048,795 cis-eQTLs

44.71% done, 740,862,834 cis-eQTLs

44.71% done, 740,893,187 cis-eQTLs

44.75% done, 741,864,967 cis-eQTLs

44.75% done, 742,306,781 cis-eQTLs

44.78% done, 742,923,717 cis-eQTLs

44.81% done, 743,579,519 cis-eQTLs

44.85% done, 744,306,072 cis-eQTLs

44.88% done, 745,082,050 cis-eQTLs

44.91% done, 745,459,129 cis-eQTLs

44.95% done, 745,898,978 cis-eQTLs

44.98% done, 746,325,995 cis-eQTLs

44.98% done, 746,347,118 cis-eQTLs

45.02% done, 746,432,664 cis-eQTLs

45.02% done, 746,686,395 cis-eQTLs

45.05% done, 747,018,377 cis-eQTLs

45.08% done, 747,573,097 cis-eQTLs

45.12% done, 748,145,765 cis-eQTLs

45.15% done, 748,617,726 cis-eQTLs

45.18% done, 749,078,289 cis-eQTLs

45.22% done, 749,516,878 cis-eQTLs

45.25% done, 749,896,990 cis-eQTLs

45.28% done, 750,204,556 cis-eQTLs

45.32% done, 750,626,778 cis-eQTLs

45.35% done, 750,914,415 cis-eQTLs

45.35% done, 751,158,345 cis-eQTLs

45.38% done, 751,175,065 cis-eQTLs

45.38% done, 752,262,038 cis-eQTLs

45.42% done, 753,147,998 cis-eQTLs

45.45% done, 753,612,701 cis-eQTLs

45.48% done, 753,972,074 cis-eQTLs

45.52% done, 754,740,562 cis-eQTLs

45.55% done, 755,313,442 cis-eQTLs

45.59% done, 755,447,870 cis-eQTLs

45.62% done, 755,547,234 cis-eQTLs

45.62% done, 755,607,368 cis-eQTLs

45.65% done, 755,630,358 cis-eQTLs

45.65% done, 756,320,207 cis-eQTLs

45.69% done, 756,805,292 cis-eQTLs

45.72% done, 756,942,573 cis-eQTLs

45.75% done, 757,050,593 cis-eQTLs

45.79% done, 757,174,209 cis-eQTLs

45.82% done, 757,318,488 cis-eQTLs

45.85% done, 757,693,199 cis-eQTLs

45.89% done, 758,471,932 cis-eQTLs

45.92% done, 759,065,224 cis-eQTLs

45.95% done, 759,261,473 cis-eQTLs

45.99% done, 759,420,749 cis-eQTLs

46.02% done, 759,443,544 cis-eQTLs

46.05% done, 759,528,071 cis-eQTLs

46.09% done, 759,849,016 cis-eQTLs

46.12% done, 760,198,350 cis-eQTLs

46.16% done, 760,355,249 cis-eQTLs

46.16% done, 760,691,108 cis-eQTLs

46.19% done, 761,029,151 cis-eQTLs

46.22% done, 761,162,337 cis-eQTLs

46.26% done, 761,254,164 cis-eQTLs

46.29% done, 761,372,635 cis-eQTLs

46.32% done, 761,656,729 cis-eQTLs

46.36% done, 761,983,334 cis-eQTLs

46.39% done, 762,153,473 cis-eQTLs

46.42% done, 762,604,359 cis-eQTLs

46.46% done, 763,556,690 cis-eQTLs

46.46% done, 763,586,598 cis-eQTLs

46.49% done, 763,759,297 cis-eQTLs

46.49% done, 764,444,431 cis-eQTLs

46.52% done, 764,851,552 cis-eQTLs

46.56% done, 765,305,383 cis-eQTLs

46.59% done, 765,564,240 cis-eQTLs

46.62% done, 765,764,966 cis-eQTLs

46.66% done, 766,044,886 cis-eQTLs

46.69% done, 766,318,633 cis-eQTLs

46.72% done, 766,544,268 cis-eQTLs

46.76% done, 766,720,273 cis-eQTLs

46.79% done, 766,920,937 cis-eQTLs

46.83% done, 767,108,118 cis-eQTLs

46.86% done, 767,162,715 cis-eQTLs

46.89% done, 767,390,615 cis-eQTLs

46.93% done, 767,784,663 cis-eQTLs

46.93% done, 767,830,635 cis-eQTLs

46.96% done, 767,863,336 cis-eQTLs

46.96% done, 767,968,553 cis-eQTLs

46.99% done, 768,084,453 cis-eQTLs

47.03% done, 768,493,628 cis-eQTLs

47.06% done, 768,784,574 cis-eQTLs

47.09% done, 769,306,079 cis-eQTLs

47.13% done, 769,793,069 cis-eQTLs

47.16% done, 770,279,158 cis-eQTLs

47.19% done, 770,734,241 cis-eQTLs

47.23% done, 771,116,166 cis-eQTLs

47.23% done, 771,132,927 cis-eQTLs

47.26% done, 771,466,418 cis-eQTLs

47.26% done, 771,940,045 cis-eQTLs

47.29% done, 771,941,587 cis-eQTLs

47.29% done, 773,345,725 cis-eQTLs

47.33% done, 774,321,516 cis-eQTLs

47.33% done, 775,056,429 cis-eQTLs

47.36% done, 775,063,319 cis-eQTLs

47.36% done, 776,236,506 cis-eQTLs

47.40% done, 776,899,679 cis-eQTLs

47.43% done, 777,189,480 cis-eQTLs

47.46% done, 777,441,185 cis-eQTLs

47.50% done, 778,092,448 cis-eQTLs

47.53% done, 778,589,014 cis-eQTLs

47.53% done, 778,597,461 cis-eQTLs

47.56% done, 778,756,047 cis-eQTLs

47.56% done, 779,159,798 cis-eQTLs

47.60% done, 779,643,541 cis-eQTLs

47.63% done, 779,702,666 cis-eQTLs

47.66% done, 779,792,122 cis-eQTLs

47.70% done, 780,102,522 cis-eQTLs

47.73% done, 780,424,741 cis-eQTLs

47.76% done, 780,599,334 cis-eQTLs

47.80% done, 780,890,152 cis-eQTLs

47.83% done, 781,512,929 cis-eQTLs

47.86% done, 781,714,969 cis-eQTLs

47.90% done, 781,775,074 cis-eQTLs

47.93% done, 781,957,797 cis-eQTLs

47.93% done, 782,124,021 cis-eQTLs

47.97% done, 782,503,675 cis-eQTLs

48.00% done, 782,851,391 cis-eQTLs

48.03% done, 783,150,935 cis-eQTLs

48.07% done, 783,354,047 cis-eQTLs

48.10% done, 783,411,584 cis-eQTLs

48.13% done, 783,509,219 cis-eQTLs

48.17% done, 784,070,027 cis-eQTLs

48.20% done, 785,124,464 cis-eQTLs

48.23% done, 785,882,196 cis-eQTLs

48.23% done, 786,045,612 cis-eQTLs

48.27% done, 786,137,232 cis-eQTLs

48.27% done, 786,894,645 cis-eQTLs

48.30% done, 787,408,136 cis-eQTLs

48.33% done, 787,814,532 cis-eQTLs

48.37% done, 788,184,515 cis-eQTLs

48.40% done, 788,875,757 cis-eQTLs

48.43% done, 789,507,784 cis-eQTLs

48.47% done, 789,762,275 cis-eQTLs

48.50% done, 789,982,339 cis-eQTLs

48.50% done, 790,132,364 cis-eQTLs

48.54% done, 790,138,008 cis-eQTLs

48.54% done, 790,744,205 cis-eQTLs

48.57% done, 791,602,442 cis-eQTLs

48.60% done, 792,386,282 cis-eQTLs

48.64% done, 792,869,984 cis-eQTLs

48.67% done, 793,488,264 cis-eQTLs

48.67% done, 793,514,426 cis-eQTLs

48.70% done, 793,615,045 cis-eQTLs

48.70% done, 793,861,474 cis-eQTLs

48.74% done, 793,967,393 cis-eQTLs

48.77% done, 794,031,812 cis-eQTLs

48.80% done, 794,113,076 cis-eQTLs

48.84% done, 794,216,663 cis-eQTLs

48.87% done, 794,479,815 cis-eQTLs

48.90% done, 795,364,596 cis-eQTLs

48.94% done, 796,252,065 cis-eQTLs

48.97% done, 797,695,096 cis-eQTLs

48.97% done, 797,765,707 cis-eQTLs

49.00% done, 798,558,288 cis-eQTLs

49.00% done, 799,620,851 cis-eQTLs

49.04% done, 800,327,378 cis-eQTLs

49.07% done, 800,599,333 cis-eQTLs

49.11% done, 800,754,198 cis-eQTLs

49.14% done, 801,114,300 cis-eQTLs

49.17% done, 802,248,768 cis-eQTLs

49.21% done, 803,524,786 cis-eQTLs

49.21% done, 803,572,752 cis-eQTLs

49.24% done, 803,889,866 cis-eQTLs

49.24% done, 804,551,679 cis-eQTLs

49.27% done, 806,493,039 cis-eQTLs

49.31% done, 808,922,042 cis-eQTLs

49.31% done, 809,031,573 cis-eQTLs

49.34% done, 810,006,683 cis-eQTLs

49.34% done, 810,888,280 cis-eQTLs

49.37% done, 810,912,551 cis-eQTLs

49.37% done, 811,831,182 cis-eQTLs

49.41% done, 813,091,932 cis-eQTLs

49.44% done, 815,047,990 cis-eQTLs

49.44% done, 815,051,654 cis-eQTLs

49.47% done, 816,508,618 cis-eQTLs

49.47% done, 817,265,233 cis-eQTLs

49.51% done, 817,724,450 cis-eQTLs

49.51% done, 818,931,787 cis-eQTLs

49.54% done, 818,933,783 cis-eQTLs

49.54% done, 819,744,591 cis-eQTLs

49.57% done, 819,993,844 cis-eQTLs

49.61% done, 820,159,855 cis-eQTLs

49.64% done, 820,304,222 cis-eQTLs

49.67% done, 820,423,604 cis-eQTLs

49.71% done, 820,523,570 cis-eQTLs

49.74% done, 820,656,254 cis-eQTLs

49.78% done, 820,795,056 cis-eQTLs

49.81% done, 820,930,131 cis-eQTLs

49.84% done, 821,011,719 cis-eQTLs

49.88% done, 821,202,611 cis-eQTLs

49.91% done, 821,697,838 cis-eQTLs

49.94% done, 822,340,779 cis-eQTLs

49.98% done, 822,777,690 cis-eQTLs

50.01% done, 823,513,924 cis-eQTLs

50.04% done, 824,137,983 cis-eQTLs

50.08% done, 824,682,759 cis-eQTLs

50.08% done, 824,701,173 cis-eQTLs

50.11% done, 825,109,049 cis-eQTLs

50.11% done, 825,618,052 cis-eQTLs

50.14% done, 825,697,597 cis-eQTLs

50.14% done, 826,797,828 cis-eQTLs

50.18% done, 827,957,544 cis-eQTLs

50.21% done, 828,441,565 cis-eQTLs

50.24% done, 828,938,034 cis-eQTLs

50.28% done, 829,226,105 cis-eQTLs

50.31% done, 829,377,460 cis-eQTLs

50.35% done, 829,446,345 cis-eQTLs

50.38% done, 829,535,150 cis-eQTLs

50.41% done, 829,681,103 cis-eQTLs

50.45% done, 829,832,765 cis-eQTLs

50.48% done, 830,114,684 cis-eQTLs

50.51% done, 830,791,732 cis-eQTLs

50.55% done, 831,514,418 cis-eQTLs

50.58% done, 831,853,292 cis-eQTLs

50.58% done, 831,936,537 cis-eQTLs

50.61% done, 832,029,513 cis-eQTLs

50.61% done, 832,461,895 cis-eQTLs

50.65% done, 832,462,716 cis-eQTLs

50.65% done, 833,157,892 cis-eQTLs

50.68% done, 833,718,808 cis-eQTLs

50.71% done, 833,947,360 cis-eQTLs

50.75% done, 834,848,649 cis-eQTLs

50.78% done, 836,318,669 cis-eQTLs

50.78% done, 836,333,377 cis-eQTLs

50.81% done, 837,046,390 cis-eQTLs

50.81% done, 837,392,457 cis-eQTLs

50.85% done, 837,468,305 cis-eQTLs

50.85% done, 837,864,489 cis-eQTLs

50.88% done, 838,400,762 cis-eQTLs

50.92% done, 839,047,688 cis-eQTLs

50.95% done, 839,690,180 cis-eQTLs

50.98% done, 840,599,396 cis-eQTLs

51.02% done, 841,499,236 cis-eQTLs

51.05% done, 841,878,354 cis-eQTLs

51.05% done, 842,255,318 cis-eQTLs

51.08% done, 842,900,577 cis-eQTLs

51.12% done, 843,128,515 cis-eQTLs

51.15% done, 843,398,327 cis-eQTLs

51.18% done, 843,774,440 cis-eQTLs

51.22% done, 843,879,695 cis-eQTLs

51.25% done, 844,068,746 cis-eQTLs

51.28% done, 844,867,870 cis-eQTLs

51.28% done, 845,046,455 cis-eQTLs

51.32% done, 845,148,939 cis-eQTLs

51.32% done, 845,669,151 cis-eQTLs

51.35% done, 845,992,181 cis-eQTLs

51.38% done, 846,318,780 cis-eQTLs

51.42% done, 847,182,926 cis-eQTLs

51.45% done, 847,900,796 cis-eQTLs

51.49% done, 848,103,898 cis-eQTLs

51.49% done, 848,114,454 cis-eQTLs

51.52% done, 848,177,350 cis-eQTLs

51.52% done, 848,751,182 cis-eQTLs

51.55% done, 848,945,839 cis-eQTLs

51.59% done, 849,037,771 cis-eQTLs

51.62% done, 849,277,796 cis-eQTLs

51.65% done, 849,682,558 cis-eQTLs

51.69% done, 850,067,989 cis-eQTLs

51.72% done, 850,588,859 cis-eQTLs

51.75% done, 850,945,746 cis-eQTLs

51.79% done, 851,517,369 cis-eQTLs

51.82% done, 851,840,820 cis-eQTLs

51.85% done, 852,119,294 cis-eQTLs

51.85% done, 852,156,382 cis-eQTLs

51.89% done, 852,245,074 cis-eQTLs

51.89% done, 852,619,040 cis-eQTLs

51.92% done, 852,868,992 cis-eQTLs

51.95% done, 853,434,984 cis-eQTLs

51.99% done, 853,844,269 cis-eQTLs

52.02% done, 854,057,396 cis-eQTLs

52.05% done, 854,308,639 cis-eQTLs

52.09% done, 854,592,614 cis-eQTLs

52.12% done, 855,082,873 cis-eQTLs

52.16% done, 855,536,325 cis-eQTLs

52.19% done, 855,712,406 cis-eQTLs

52.19% done, 855,757,034 cis-eQTLs

52.22% done, 855,768,169 cis-eQTLs

52.22% done, 856,066,019 cis-eQTLs

52.26% done, 856,555,617 cis-eQTLs

52.29% done, 856,858,188 cis-eQTLs

52.32% done, 857,258,939 cis-eQTLs

52.36% done, 857,645,042 cis-eQTLs

52.39% done, 858,210,057 cis-eQTLs

52.42% done, 858,505,281 cis-eQTLs

52.46% done, 858,642,250 cis-eQTLs

52.49% done, 858,900,223 cis-eQTLs

52.52% done, 858,972,144 cis-eQTLs

52.56% done, 859,143,217 cis-eQTLs

52.59% done, 859,490,843 cis-eQTLs

52.62% done, 859,838,753 cis-eQTLs

52.62% done, 860,033,913 cis-eQTLs

52.66% done, 860,035,843 cis-eQTLs

52.66% done, 860,423,582 cis-eQTLs

52.69% done, 860,492,468 cis-eQTLs

52.73% done, 860,538,611 cis-eQTLs

52.76% done, 860,642,381 cis-eQTLs

52.79% done, 860,998,475 cis-eQTLs

52.83% done, 861,240,030 cis-eQTLs

52.86% done, 861,342,051 cis-eQTLs

52.89% done, 861,472,844 cis-eQTLs

52.93% done, 861,741,068 cis-eQTLs

52.96% done, 862,040,416 cis-eQTLs

52.99% done, 862,347,878 cis-eQTLs

53.03% done, 862,899,191 cis-eQTLs

53.06% done, 863,321,962 cis-eQTLs

53.06% done, 863,573,910 cis-eQTLs

53.09% done, 863,605,711 cis-eQTLs

53.09% done, 863,970,906 cis-eQTLs

53.13% done, 864,458,160 cis-eQTLs

53.16% done, 864,965,942 cis-eQTLs

53.19% done, 865,465,275 cis-eQTLs

53.23% done, 866,249,939 cis-eQTLs

53.26% done, 866,972,630 cis-eQTLs

53.26% done, 867,004,790 cis-eQTLs

53.30% done, 867,110,997 cis-eQTLs

53.30% done, 867,716,452 cis-eQTLs

53.33% done, 868,452,380 cis-eQTLs

53.36% done, 868,822,332 cis-eQTLs

53.40% done, 869,143,505 cis-eQTLs

53.43% done, 869,397,402 cis-eQTLs

53.46% done, 869,661,111 cis-eQTLs

53.50% done, 869,885,516 cis-eQTLs

53.53% done, 870,162,380 cis-eQTLs

53.56% done, 870,545,276 cis-eQTLs

53.60% done, 870,617,240 cis-eQTLs

53.63% done, 870,674,454 cis-eQTLs

53.66% done, 870,805,632 cis-eQTLs

53.70% done, 870,883,999 cis-eQTLs

53.73% done, 871,034,400 cis-eQTLs

53.76% done, 871,269,902 cis-eQTLs

53.76% done, 871,446,275 cis-eQTLs

53.80% done, 871,452,390 cis-eQTLs

53.80% done, 871,900,693 cis-eQTLs

53.83% done, 872,396,652 cis-eQTLs

53.87% done, 872,873,760 cis-eQTLs

53.90% done, 873,261,055 cis-eQTLs

53.93% done, 873,540,646 cis-eQTLs

53.97% done, 873,899,261 cis-eQTLs

54.00% done, 874,845,252 cis-eQTLs

54.03% done, 875,319,518 cis-eQTLs

54.03% done, 875,586,225 cis-eQTLs

54.07% done, 875,650,431 cis-eQTLs

54.07% done, 876,424,895 cis-eQTLs

54.10% done, 876,909,868 cis-eQTLs

54.13% done, 877,417,380 cis-eQTLs

54.17% done, 878,160,413 cis-eQTLs

54.20% done, 878,651,715 cis-eQTLs

54.23% done, 879,065,069 cis-eQTLs

54.27% done, 879,680,662 cis-eQTLs

54.30% done, 879,938,587 cis-eQTLs

54.30% done, 879,940,821 cis-eQTLs

54.33% done, 880,004,211 cis-eQTLs

54.33% done, 880,213,126 cis-eQTLs

54.37% done, 880,218,463 cis-eQTLs

54.37% done, 880,837,586 cis-eQTLs

54.40% done, 881,651,473 cis-eQTLs

54.43% done, 882,066,643 cis-eQTLs

54.47% done, 882,474,978 cis-eQTLs

54.50% done, 882,675,407 cis-eQTLs

54.54% done, 882,790,294 cis-eQTLs

54.57% done, 882,877,087 cis-eQTLs

54.60% done, 882,991,706 cis-eQTLs

54.64% done, 883,271,426 cis-eQTLs

54.67% done, 883,875,634 cis-eQTLs

54.70% done, 884,860,727 cis-eQTLs

54.70% done, 885,097,651 cis-eQTLs

54.74% done, 885,147,837 cis-eQTLs

54.74% done, 886,705,434 cis-eQTLs

54.77% done, 887,992,187 cis-eQTLs

54.80% done, 889,546,171 cis-eQTLs

54.80% done, 889,756,488 cis-eQTLs

54.84% done, 890,435,579 cis-eQTLs

54.84% done, 892,425,164 cis-eQTLs

54.87% done, 892,430,103 cis-eQTLs

54.87% done, 893,749,340 cis-eQTLs

54.87% done, 894,166,972 cis-eQTLs

54.90% done, 894,548,837 cis-eQTLs

54.94% done, 895,003,781 cis-eQTLs

54.97% done, 895,241,122 cis-eQTLs

55.00% done, 895,532,255 cis-eQTLs

55.04% done, 895,846,659 cis-eQTLs

55.07% done, 896,085,768 cis-eQTLs

55.11% done, 896,492,648 cis-eQTLs

55.14% done, 896,960,393 cis-eQTLs

55.17% done, 897,362,256 cis-eQTLs

55.21% done, 897,766,292 cis-eQTLs

55.24% done, 898,044,920 cis-eQTLs

55.27% done, 898,164,076 cis-eQTLs

55.31% done, 898,260,907 cis-eQTLs

55.34% done, 898,362,360 cis-eQTLs

55.37% done, 898,393,587 cis-eQTLs

55.41% done, 898,433,015 cis-eQTLs

55.44% done, 898,477,748 cis-eQTLs

55.47% done, 898,501,606 cis-eQTLs

55.51% done, 898,515,876 cis-eQTLs

55.54% done, 898,628,824 cis-eQTLs

55.57% done, 898,830,067 cis-eQTLs

55.61% done, 898,974,960 cis-eQTLs

55.61% done, 899,098,904 cis-eQTLs

55.64% done, 899,135,344 cis-eQTLs

55.64% done, 899,461,568 cis-eQTLs

55.68% done, 899,765,055 cis-eQTLs

55.71% done, 900,060,015 cis-eQTLs

55.74% done, 900,278,001 cis-eQTLs

55.78% done, 900,408,684 cis-eQTLs

55.81% done, 900,596,775 cis-eQTLs

55.84% done, 900,928,925 cis-eQTLs

55.88% done, 901,177,314 cis-eQTLs

55.91% done, 901,447,458 cis-eQTLs

55.94% done, 901,782,842 cis-eQTLs

55.98% done, 901,931,062 cis-eQTLs

56.01% done, 902,051,836 cis-eQTLs

56.04% done, 902,093,759 cis-eQTLs

56.08% done, 902,142,018 cis-eQTLs

56.11% done, 902,295,251 cis-eQTLs

56.14% done, 902,617,101 cis-eQTLs

56.18% done, 902,713,026 cis-eQTLs

56.21% done, 902,771,777 cis-eQTLs

56.24% done, 902,826,975 cis-eQTLs

56.28% done, 902,858,201 cis-eQTLs

56.31% done, 902,905,052 cis-eQTLs

56.35% done, 902,953,452 cis-eQTLs

56.38% done, 903,141,402 cis-eQTLs

56.41% done, 903,728,112 cis-eQTLs

56.45% done, 904,120,208 cis-eQTLs

56.45% done, 904,293,164 cis-eQTLs

56.48% done, 904,319,282 cis-eQTLs

56.48% done, 905,096,779 cis-eQTLs

56.51% done, 905,980,036 cis-eQTLs

56.55% done, 906,610,393 cis-eQTLs

56.58% done, 907,240,523 cis-eQTLs

56.61% done, 907,417,364 cis-eQTLs

56.65% done, 907,424,670 cis-eQTLs

56.68% done, 907,438,119 cis-eQTLs

56.71% done, 907,687,876 cis-eQTLs

56.71% done, 907,727,614 cis-eQTLs

56.75% done, 907,896,427 cis-eQTLs

56.75% done, 908,186,819 cis-eQTLs

56.78% done, 908,503,293 cis-eQTLs

56.81% done, 908,709,815 cis-eQTLs

56.85% done, 909,071,206 cis-eQTLs

56.88% done, 909,210,598 cis-eQTLs

56.92% done, 909,395,291 cis-eQTLs

56.95% done, 909,561,802 cis-eQTLs

56.98% done, 909,793,670 cis-eQTLs

57.02% done, 910,148,800 cis-eQTLs

57.05% done, 910,467,134 cis-eQTLs

57.08% done, 910,632,616 cis-eQTLs

57.12% done, 910,799,747 cis-eQTLs

57.15% done, 910,866,400 cis-eQTLs

57.18% done, 910,975,487 cis-eQTLs

57.22% done, 911,152,285 cis-eQTLs

57.25% done, 911,424,680 cis-eQTLs

57.28% done, 911,754,378 cis-eQTLs

57.32% done, 911,945,539 cis-eQTLs

57.35% done, 912,065,168 cis-eQTLs

57.35% done, 912,277,812 cis-eQTLs

57.38% done, 912,731,763 cis-eQTLs

57.42% done, 913,126,984 cis-eQTLs

57.45% done, 913,610,161 cis-eQTLs

57.49% done, 914,025,971 cis-eQTLs

57.52% done, 914,347,929 cis-eQTLs

57.55% done, 914,819,780 cis-eQTLs

57.59% done, 915,426,252 cis-eQTLs

57.62% done, 916,207,887 cis-eQTLs

57.65% done, 916,598,163 cis-eQTLs

57.65% done, 916,747,557 cis-eQTLs

57.69% done, 916,774,202 cis-eQTLs

57.69% done, 917,438,267 cis-eQTLs

57.72% done, 918,071,201 cis-eQTLs

57.75% done, 918,729,916 cis-eQTLs

57.79% done, 919,359,277 cis-eQTLs

57.82% done, 919,799,521 cis-eQTLs

57.85% done, 920,052,443 cis-eQTLs

57.89% done, 920,314,087 cis-eQTLs

57.92% done, 920,359,810 cis-eQTLs

57.95% done, 920,375,132 cis-eQTLs

57.95% done, 920,380,305 cis-eQTLs

57.99% done, 920,383,735 cis-eQTLs

57.99% done, 920,424,601 cis-eQTLs

58.02% done, 920,607,256 cis-eQTLs

58.05% done, 921,001,330 cis-eQTLs

58.09% done, 921,228,120 cis-eQTLs

58.12% done, 921,580,981 cis-eQTLs

58.16% done, 921,885,433 cis-eQTLs

58.19% done, 922,246,438 cis-eQTLs

58.22% done, 922,770,247 cis-eQTLs

58.26% done, 923,239,873 cis-eQTLs

58.29% done, 923,599,541 cis-eQTLs

58.32% done, 924,005,916 cis-eQTLs

58.36% done, 924,487,903 cis-eQTLs

58.39% done, 925,153,824 cis-eQTLs

58.39% done, 925,165,574 cis-eQTLs

58.42% done, 925,426,433 cis-eQTLs

58.42% done, 925,989,804 cis-eQTLs

58.46% done, 926,506,155 cis-eQTLs

58.49% done, 926,761,165 cis-eQTLs

58.52% done, 927,021,076 cis-eQTLs

58.56% done, 927,226,179 cis-eQTLs

58.59% done, 927,324,140 cis-eQTLs

58.62% done, 927,442,473 cis-eQTLs

58.66% done, 928,007,514 cis-eQTLs

58.69% done, 928,856,761 cis-eQTLs

58.73% done, 929,238,377 cis-eQTLs

58.73% done, 929,520,250 cis-eQTLs

58.76% done, 930,257,622 cis-eQTLs

58.79% done, 930,946,843 cis-eQTLs

58.83% done, 931,913,316 cis-eQTLs

58.83% done, 931,933,878 cis-eQTLs

58.86% done, 932,316,224 cis-eQTLs

58.86% done, 933,424,267 cis-eQTLs

58.89% done, 934,580,985 cis-eQTLs

58.93% done, 935,487,875 cis-eQTLs

58.93% done, 935,540,861 cis-eQTLs

58.96% done, 935,824,359 cis-eQTLs

58.96% done, 936,577,804 cis-eQTLs

58.99% done, 937,546,840 cis-eQTLs

59.03% done, 938,911,824 cis-eQTLs

59.06% done, 940,155,400 cis-eQTLs

59.06% done, 940,156,642 cis-eQTLs

59.09% done, 940,802,353 cis-eQTLs

59.09% done, 941,307,075 cis-eQTLs

59.13% done, 941,373,840 cis-eQTLs

59.13% done, 942,542,778 cis-eQTLs

59.16% done, 944,339,583 cis-eQTLs

59.16% done, 944,343,314 cis-eQTLs

59.19% done, 945,580,092 cis-eQTLs

59.19% done, 946,712,323 cis-eQTLs

59.23% done, 947,984,891 cis-eQTLs

59.23% done, 947,996,601 cis-eQTLs

59.26% done, 949,144,531 cis-eQTLs

59.26% done, 949,781,209 cis-eQTLs

59.30% done, 949,922,811 cis-eQTLs

59.30% done, 950,865,117 cis-eQTLs

59.33% done, 951,333,864 cis-eQTLs

59.36% done, 952,269,904 cis-eQTLs

59.40% done, 953,399,249 cis-eQTLs

59.43% done, 954,057,154 cis-eQTLs

59.46% done, 954,570,825 cis-eQTLs

59.50% done, 955,391,946 cis-eQTLs

59.50% done, 955,504,427 cis-eQTLs

59.53% done, 955,874,762 cis-eQTLs

59.53% done, 956,710,589 cis-eQTLs

59.56% done, 957,285,599 cis-eQTLs

59.60% done, 958,054,276 cis-eQTLs

59.63% done, 958,736,411 cis-eQTLs

59.66% done, 958,988,793 cis-eQTLs

59.70% done, 959,083,245 cis-eQTLs

59.73% done, 959,291,989 cis-eQTLs

59.76% done, 960,042,912 cis-eQTLs

59.80% done, 960,859,163 cis-eQTLs

59.80% done, 960,859,563 cis-eQTLs

59.83% done, 961,218,074 cis-eQTLs

59.83% done, 961,458,819 cis-eQTLs

59.87% done, 961,505,233 cis-eQTLs

59.87% done, 962,319,346 cis-eQTLs

59.90% done, 963,069,247 cis-eQTLs

59.93% done, 963,861,890 cis-eQTLs

59.97% done, 964,475,290 cis-eQTLs

60.00% done, 964,790,499 cis-eQTLs

60.03% done, 965,320,875 cis-eQTLs

60.07% done, 965,652,423 cis-eQTLs

60.10% done, 966,005,324 cis-eQTLs

60.13% done, 966,192,490 cis-eQTLs

60.17% done, 966,402,059 cis-eQTLs

60.20% done, 966,546,452 cis-eQTLs

60.23% done, 966,734,572 cis-eQTLs

60.23% done, 967,031,524 cis-eQTLs

60.27% done, 967,623,110 cis-eQTLs

60.30% done, 967,963,444 cis-eQTLs

60.33% done, 968,336,459 cis-eQTLs

60.37% done, 968,592,254 cis-eQTLs

60.40% done, 969,044,678 cis-eQTLs

60.44% done, 969,623,150 cis-eQTLs

60.47% done, 970,118,573 cis-eQTLs

60.50% done, 970,688,157 cis-eQTLs

60.50% done, 970,689,708 cis-eQTLs

60.54% done, 971,008,827 cis-eQTLs

60.54% done, 971,255,809 cis-eQTLs

60.57% done, 971,306,017 cis-eQTLs

60.57% done, 971,905,265 cis-eQTLs

60.60% done, 972,526,062 cis-eQTLs

60.64% done, 973,042,879 cis-eQTLs

60.67% done, 973,495,657 cis-eQTLs

60.70% done, 974,012,249 cis-eQTLs

60.74% done, 974,416,752 cis-eQTLs

60.77% done, 975,060,063 cis-eQTLs

60.80% done, 975,260,205 cis-eQTLs

60.84% done, 975,392,800 cis-eQTLs

60.87% done, 975,638,287 cis-eQTLs

60.87% done, 975,666,019 cis-eQTLs

60.90% done, 975,724,144 cis-eQTLs

60.90% done, 975,764,257 cis-eQTLs

60.94% done, 975,795,506 cis-eQTLs

60.97% done, 976,035,852 cis-eQTLs

61.01% done, 976,928,585 cis-eQTLs

61.04% done, 977,687,731 cis-eQTLs

61.07% done, 978,278,125 cis-eQTLs

61.11% done, 978,858,269 cis-eQTLs

61.14% done, 979,096,191 cis-eQTLs

61.17% done, 979,771,584 cis-eQTLs

61.17% done, 979,858,589 cis-eQTLs

61.21% done, 980,043,529 cis-eQTLs

61.21% done, 980,572,107 cis-eQTLs

61.24% done, 980,975,672 cis-eQTLs

61.27% done, 981,181,419 cis-eQTLs

61.31% done, 981,415,005 cis-eQTLs

61.34% done, 981,593,641 cis-eQTLs

61.37% done, 981,670,430 cis-eQTLs

61.41% done, 981,734,484 cis-eQTLs

61.44% done, 981,800,655 cis-eQTLs

61.47% done, 981,875,332 cis-eQTLs

61.51% done, 981,941,077 cis-eQTLs

61.54% done, 981,967,423 cis-eQTLs

61.57% done, 982,089,172 cis-eQTLs

61.61% done, 982,474,360 cis-eQTLs

61.64% done, 982,869,204 cis-eQTLs

61.68% done, 983,352,192 cis-eQTLs

61.71% done, 983,822,772 cis-eQTLs

61.74% done, 984,084,674 cis-eQTLs

61.74% done, 984,349,031 cis-eQTLs

61.78% done, 984,352,395 cis-eQTLs

61.78% done, 984,763,454 cis-eQTLs

61.81% done, 984,836,613 cis-eQTLs

61.84% done, 984,891,387 cis-eQTLs

61.88% done, 984,948,796 cis-eQTLs

61.91% done, 985,038,838 cis-eQTLs

61.94% done, 985,225,059 cis-eQTLs

61.98% done, 985,911,782 cis-eQTLs

62.01% done, 986,854,636 cis-eQTLs

62.04% done, 987,941,205 cis-eQTLs

62.08% done, 988,912,394 cis-eQTLs

62.08% done, 989,042,596 cis-eQTLs

62.11% done, 989,297,184 cis-eQTLs

62.11% done, 990,062,894 cis-eQTLs

62.14% done, 991,141,050 cis-eQTLs

62.18% done, 992,015,721 cis-eQTLs

62.21% done, 992,476,317 cis-eQTLs

62.21% done, 992,663,980 cis-eQTLs

62.25% done, 992,971,710 cis-eQTLs

62.28% done, 993,693,717 cis-eQTLs

62.31% done, 994,515,667 cis-eQTLs

62.35% done, 995,290,148 cis-eQTLs

62.38% done, 995,918,550 cis-eQTLs

62.41% done, 996,306,395 cis-eQTLs

62.45% done, 996,398,880 cis-eQTLs

62.48% done, 996,515,137 cis-eQTLs

62.51% done, 996,632,568 cis-eQTLs

62.55% done, 996,937,407 cis-eQTLs

62.55% done, 997,009,852 cis-eQTLs

62.58% done, 997,165,607 cis-eQTLs

62.58% done, 997,351,879 cis-eQTLs

62.61% done, 997,535,611 cis-eQTLs

62.65% done, 998,202,246 cis-eQTLs

62.68% done, 998,784,629 cis-eQTLs

62.71% done, 999,443,769 cis-eQTLs

62.75% done, 1,000,077,034 cis-eQTLs

62.78% done, 1,000,367,691 cis-eQTLs

62.82% done, 1,000,885,826 cis-eQTLs

62.85% done, 1,001,123,965 cis-eQTLs

62.85% done, 1,001,518,351 cis-eQTLs

62.88% done, 1,002,243,386 cis-eQTLs

62.92% done, 1,002,756,954 cis-eQTLs

62.95% done, 1,003,339,575 cis-eQTLs

62.98% done, 1,004,106,122 cis-eQTLs

63.02% done, 1,005,051,304 cis-eQTLs

63.02% done, 1,005,195,068 cis-eQTLs

63.05% done, 1,005,354,869 cis-eQTLs

63.05% done, 1,005,882,766 cis-eQTLs

63.08% done, 1,006,437,885 cis-eQTLs

63.12% done, 1,007,616,096 cis-eQTLs

63.15% done, 1,008,778,031 cis-eQTLs

63.15% done, 1,009,080,634 cis-eQTLs

63.18% done, 1,010,268,750 cis-eQTLs

63.22% done, 1,011,248,896 cis-eQTLs

63.25% done, 1,011,365,892 cis-eQTLs

63.28% done, 1,011,473,702 cis-eQTLs

63.32% done, 1,011,647,830 cis-eQTLs

63.35% done, 1,011,744,215 cis-eQTLs

63.39% done, 1,011,841,734 cis-eQTLs

63.42% done, 1,011,971,344 cis-eQTLs

63.42% done, 1,012,080,379 cis-eQTLs

63.45% done, 1,012,105,479 cis-eQTLs

63.45% done, 1,012,895,878 cis-eQTLs

63.49% done, 1,013,135,529 cis-eQTLs

63.52% done, 1,013,733,838 cis-eQTLs

63.55% done, 1,014,446,963 cis-eQTLs

63.59% done, 1,015,106,896 cis-eQTLs

63.62% done, 1,015,366,915 cis-eQTLs

63.62% done, 1,015,367,533 cis-eQTLs

63.65% done, 1,015,691,647 cis-eQTLs

63.65% done, 1,016,150,697 cis-eQTLs

63.69% done, 1,016,709,251 cis-eQTLs

63.72% done, 1,017,539,823 cis-eQTLs

63.75% done, 1,018,222,993 cis-eQTLs

63.79% done, 1,018,540,144 cis-eQTLs

63.82% done, 1,019,194,065 cis-eQTLs

63.85% done, 1,020,010,951 cis-eQTLs

63.85% done, 1,020,077,567 cis-eQTLs

63.89% done, 1,020,246,645 cis-eQTLs

63.89% done, 1,020,906,564 cis-eQTLs

63.92% done, 1,021,815,201 cis-eQTLs

63.96% done, 1,022,972,994 cis-eQTLs

63.99% done, 1,023,714,904 cis-eQTLs

64.02% done, 1,024,247,931 cis-eQTLs

64.06% done, 1,024,664,918 cis-eQTLs

64.09% done, 1,025,154,614 cis-eQTLs

64.09% done, 1,025,274,890 cis-eQTLs

64.12% done, 1,025,478,236 cis-eQTLs

64.12% done, 1,025,986,353 cis-eQTLs

64.16% done, 1,026,737,271 cis-eQTLs

64.19% done, 1,027,922,868 cis-eQTLs

64.22% done, 1,028,530,222 cis-eQTLs

64.26% done, 1,029,180,037 cis-eQTLs

64.29% done, 1,030,265,872 cis-eQTLs

64.29% done, 1,030,330,593 cis-eQTLs

64.32% done, 1,031,373,106 cis-eQTLs

64.32% done, 1,032,705,444 cis-eQTLs

64.36% done, 1,032,725,908 cis-eQTLs

64.36% done, 1,035,848,802 cis-eQTLs

64.36% done, 1,035,978,303 cis-eQTLs

64.39% done, 1,036,452,985 cis-eQTLs

64.39% done, 1,038,178,206 cis-eQTLs

64.42% done, 1,040,901,168 cis-eQTLs

64.42% done, 1,041,312,890 cis-eQTLs

64.46% done, 1,041,858,261 cis-eQTLs

64.46% done, 1,043,994,152 cis-eQTLs

64.49% done, 1,046,667,713 cis-eQTLs

64.49% done, 1,046,856,606 cis-eQTLs

64.53% done, 1,047,467,133 cis-eQTLs

64.53% done, 1,048,809,290 cis-eQTLs

64.56% done, 1,049,804,490 cis-eQTLs

64.59% done, 1,050,424,067 cis-eQTLs

64.63% done, 1,050,950,187 cis-eQTLs

64.66% done, 1,051,613,741 cis-eQTLs

64.69% done, 1,052,298,245 cis-eQTLs

64.73% done, 1,053,307,286 cis-eQTLs

64.73% done, 1,053,361,587 cis-eQTLs

64.76% done, 1,053,912,823 cis-eQTLs

64.76% done, 1,054,312,973 cis-eQTLs

64.79% done, 1,055,042,284 cis-eQTLs

64.83% done, 1,055,956,144 cis-eQTLs

64.86% done, 1,056,957,889 cis-eQTLs

64.89% done, 1,057,711,084 cis-eQTLs

64.93% done, 1,058,546,888 cis-eQTLs

64.96% done, 1,059,014,089 cis-eQTLs

64.96% done, 1,059,128,449 cis-eQTLs

64.99% done, 1,059,241,705 cis-eQTLs

64.99% done, 1,060,004,729 cis-eQTLs

65.03% done, 1,060,753,170 cis-eQTLs

65.06% done, 1,061,240,317 cis-eQTLs

65.10% done, 1,061,783,666 cis-eQTLs

65.13% done, 1,062,176,718 cis-eQTLs

65.16% done, 1,062,948,342 cis-eQTLs

65.16% done, 1,062,948,579 cis-eQTLs

65.20% done, 1,063,398,576 cis-eQTLs

65.20% done, 1,063,878,323 cis-eQTLs

65.23% done, 1,063,879,629 cis-eQTLs

65.23% done, 1,064,642,281 cis-eQTLs

65.26% done, 1,065,301,223 cis-eQTLs

65.30% done, 1,065,844,796 cis-eQTLs

65.33% done, 1,066,000,172 cis-eQTLs

65.36% done, 1,066,144,309 cis-eQTLs

65.40% done, 1,066,435,972 cis-eQTLs

65.43% done, 1,066,543,280 cis-eQTLs

65.46% done, 1,066,647,664 cis-eQTLs

65.50% done, 1,066,728,677 cis-eQTLs

65.53% done, 1,066,754,672 cis-eQTLs

65.56% done, 1,066,847,250 cis-eQTLs

65.60% done, 1,067,059,167 cis-eQTLs

65.63% done, 1,067,569,349 cis-eQTLs

65.66% done, 1,067,832,304 cis-eQTLs

65.70% done, 1,067,988,061 cis-eQTLs

65.70% done, 1,068,038,736 cis-eQTLs

65.73% done, 1,068,073,841 cis-eQTLs

65.73% done, 1,068,413,120 cis-eQTLs

65.77% done, 1,069,140,276 cis-eQTLs

65.80% done, 1,069,817,594 cis-eQTLs

65.83% done, 1,070,679,903 cis-eQTLs

65.87% done, 1,071,457,818 cis-eQTLs

65.90% done, 1,072,108,503 cis-eQTLs

65.90% done, 1,072,171,359 cis-eQTLs

65.93% done, 1,072,382,189 cis-eQTLs

65.93% done, 1,072,606,571 cis-eQTLs

65.97% done, 1,072,648,493 cis-eQTLs

66.00% done, 1,072,701,109 cis-eQTLs

66.03% done, 1,072,751,680 cis-eQTLs

66.07% done, 1,072,849,761 cis-eQTLs

66.10% done, 1,072,969,994 cis-eQTLs

66.13% done, 1,073,039,541 cis-eQTLs

66.17% done, 1,073,389,131 cis-eQTLs

66.20% done, 1,074,329,271 cis-eQTLs

66.23% done, 1,075,393,982 cis-eQTLs

66.27% done, 1,076,332,599 cis-eQTLs

66.27% done, 1,076,632,168 cis-eQTLs

66.30% done, 1,077,643,179 cis-eQTLs

66.34% done, 1,077,790,576 cis-eQTLs

66.37% done, 1,077,867,173 cis-eQTLs

66.40% done, 1,077,959,330 cis-eQTLs

66.44% done, 1,078,022,693 cis-eQTLs

66.47% done, 1,078,031,452 cis-eQTLs

66.50% done, 1,078,064,829 cis-eQTLs

66.54% done, 1,078,207,268 cis-eQTLs

66.57% done, 1,078,417,347 cis-eQTLs

66.60% done, 1,078,672,498 cis-eQTLs

66.64% done, 1,079,140,968 cis-eQTLs

66.67% done, 1,079,878,760 cis-eQTLs

66.67% done, 1,079,992,304 cis-eQTLs

66.70% done, 1,080,017,809 cis-eQTLs

66.70% done, 1,080,548,736 cis-eQTLs

66.74% done, 1,081,259,727 cis-eQTLs

66.77% done, 1,082,568,509 cis-eQTLs

66.77% done, 1,082,568,751 cis-eQTLs

66.80% done, 1,083,259,390 cis-eQTLs

66.80% done, 1,084,194,505 cis-eQTLs

66.84% done, 1,085,540,978 cis-eQTLs

66.87% done, 1,086,316,580 cis-eQTLs

66.87% done, 1,088,043,450 cis-eQTLs

66.91% done, 1,088,986,789 cis-eQTLs

66.91% done, 1,090,274,488 cis-eQTLs

66.94% done, 1,091,742,360 cis-eQTLs

66.94% done, 1,091,864,653 cis-eQTLs

66.97% done, 1,092,049,006 cis-eQTLs

66.97% done, 1,093,356,301 cis-eQTLs

67.01% done, 1,094,896,092 cis-eQTLs

67.04% done, 1,096,194,929 cis-eQTLs

67.04% done, 1,096,441,715 cis-eQTLs

67.07% done, 1,096,523,777 cis-eQTLs

67.07% done, 1,097,421,816 cis-eQTLs

67.11% done, 1,098,477,273 cis-eQTLs

67.14% done, 1,099,328,001 cis-eQTLs

67.17% done, 1,099,759,949 cis-eQTLs

67.17% done, 1,100,301,616 cis-eQTLs

67.21% done, 1,100,301,775 cis-eQTLs

67.21% done, 1,101,281,948 cis-eQTLs

67.24% done, 1,102,140,436 cis-eQTLs

67.27% done, 1,102,838,194 cis-eQTLs

67.31% done, 1,103,158,139 cis-eQTLs

67.34% done, 1,103,248,116 cis-eQTLs

67.37% done, 1,103,296,538 cis-eQTLs

67.41% done, 1,103,354,904 cis-eQTLs

67.44% done, 1,103,474,926 cis-eQTLs

67.44% done, 1,103,749,777 cis-eQTLs

67.48% done, 1,103,751,289 cis-eQTLs

67.48% done, 1,104,088,138 cis-eQTLs

67.51% done, 1,104,240,189 cis-eQTLs

67.54% done, 1,104,855,424 cis-eQTLs

67.58% done, 1,105,451,986 cis-eQTLs

67.61% done, 1,105,733,084 cis-eQTLs

67.64% done, 1,105,942,098 cis-eQTLs

67.68% done, 1,106,134,621 cis-eQTLs

67.71% done, 1,106,283,458 cis-eQTLs

67.74% done, 1,106,379,577 cis-eQTLs

67.78% done, 1,106,461,559 cis-eQTLs

67.81% done, 1,106,714,996 cis-eQTLs

67.84% done, 1,107,284,804 cis-eQTLs

67.88% done, 1,107,811,945 cis-eQTLs

67.88% done, 1,107,972,052 cis-eQTLs

67.91% done, 1,107,995,071 cis-eQTLs

67.91% done, 1,108,501,782 cis-eQTLs

67.94% done, 1,108,782,381 cis-eQTLs

67.98% done, 1,108,824,458 cis-eQTLs

68.01% done, 1,108,858,095 cis-eQTLs

68.05% done, 1,108,934,863 cis-eQTLs

68.08% done, 1,109,010,373 cis-eQTLs

68.11% done, 1,109,081,353 cis-eQTLs

68.15% done, 1,109,335,444 cis-eQTLs

68.18% done, 1,109,610,834 cis-eQTLs

68.21% done, 1,110,210,037 cis-eQTLs

68.25% done, 1,110,689,927 cis-eQTLs

68.28% done, 1,110,943,632 cis-eQTLs

68.31% done, 1,111,180,087 cis-eQTLs

68.35% done, 1,111,446,236 cis-eQTLs

68.38% done, 1,111,671,174 cis-eQTLs

68.41% done, 1,111,950,587 cis-eQTLs

68.45% done, 1,112,327,587 cis-eQTLs

68.45% done, 1,112,553,492 cis-eQTLs

68.48% done, 1,112,865,167 cis-eQTLs

68.51% done, 1,113,277,694 cis-eQTLs

68.55% done, 1,114,079,127 cis-eQTLs

68.58% done, 1,114,644,135 cis-eQTLs

68.62% done, 1,115,415,681 cis-eQTLs

68.65% done, 1,115,923,137 cis-eQTLs

68.65% done, 1,115,965,833 cis-eQTLs

68.68% done, 1,116,018,462 cis-eQTLs

68.68% done, 1,116,443,971 cis-eQTLs

68.72% done, 1,117,158,997 cis-eQTLs

68.75% done, 1,118,335,278 cis-eQTLs

68.78% done, 1,119,651,635 cis-eQTLs

68.78% done, 1,119,714,472 cis-eQTLs

68.82% done, 1,120,286,126 cis-eQTLs

68.82% done, 1,121,280,416 cis-eQTLs

68.85% done, 1,122,278,567 cis-eQTLs

68.88% done, 1,122,988,930 cis-eQTLs

68.92% done, 1,123,626,428 cis-eQTLs

68.95% done, 1,124,339,025 cis-eQTLs

68.95% done, 1,124,470,747 cis-eQTLs

68.98% done, 1,124,605,735 cis-eQTLs

68.98% done, 1,125,087,159 cis-eQTLs

69.02% done, 1,126,040,107 cis-eQTLs

69.05% done, 1,127,062,234 cis-eQTLs

69.08% done, 1,128,079,206 cis-eQTLs

69.12% done, 1,128,504,149 cis-eQTLs

69.15% done, 1,128,776,524 cis-eQTLs

69.18% done, 1,129,432,382 cis-eQTLs

69.19% done, 1,129,711,901 cis-eQTLs

69.22% done, 1,129,731,174 cis-eQTLs

69.22% done, 1,130,448,609 cis-eQTLs

69.25% done, 1,131,150,737 cis-eQTLs

69.29% done, 1,131,639,882 cis-eQTLs

69.32% done, 1,132,092,891 cis-eQTLs

69.35% done, 1,132,504,163 cis-eQTLs

69.39% done, 1,133,536,964 cis-eQTLs

69.39% done, 1,133,553,857 cis-eQTLs

69.42% done, 1,134,228,151 cis-eQTLs

69.42% done, 1,134,371,937 cis-eQTLs

69.45% done, 1,134,414,472 cis-eQTLs

69.45% done, 1,135,154,830 cis-eQTLs

69.49% done, 1,136,066,684 cis-eQTLs

69.52% done, 1,137,188,153 cis-eQTLs

69.55% done, 1,138,339,119 cis-eQTLs

69.55% done, 1,138,363,509 cis-eQTLs

69.59% done, 1,138,858,807 cis-eQTLs

69.59% done, 1,139,317,804 cis-eQTLs

69.62% done, 1,139,318,276 cis-eQTLs

69.62% done, 1,140,200,408 cis-eQTLs

69.65% done, 1,140,832,895 cis-eQTLs

69.69% done, 1,142,297,304 cis-eQTLs

69.69% done, 1,142,324,262 cis-eQTLs

69.72% done, 1,143,212,416 cis-eQTLs

69.72% done, 1,143,991,815 cis-eQTLs

69.76% done, 1,144,591,696 cis-eQTLs

69.79% done, 1,145,201,323 cis-eQTLs

69.82% done, 1,145,807,341 cis-eQTLs

69.86% done, 1,146,498,624 cis-eQTLs

69.89% done, 1,147,004,214 cis-eQTLs

69.92% done, 1,147,594,689 cis-eQTLs

69.96% done, 1,148,080,328 cis-eQTLs

69.96% done, 1,148,545,591 cis-eQTLs

69.99% done, 1,148,557,089 cis-eQTLs

69.99% done, 1,149,063,078 cis-eQTLs

70.02% done, 1,149,491,806 cis-eQTLs

70.06% done, 1,150,022,876 cis-eQTLs

70.09% done, 1,150,255,887 cis-eQTLs

70.12% done, 1,150,331,098 cis-eQTLs

70.16% done, 1,150,533,795 cis-eQTLs

70.19% done, 1,150,872,553 cis-eQTLs

70.22% done, 1,151,133,184 cis-eQTLs

70.26% done, 1,151,339,646 cis-eQTLs

70.29% done, 1,151,686,713 cis-eQTLs

70.32% done, 1,152,056,486 cis-eQTLs

70.36% done, 1,152,234,354 cis-eQTLs

70.36% done, 1,152,247,709 cis-eQTLs

70.39% done, 1,152,301,917 cis-eQTLs

70.39% done, 1,152,683,404 cis-eQTLs

70.43% done, 1,153,235,673 cis-eQTLs

70.46% done, 1,153,808,471 cis-eQTLs

70.49% done, 1,154,429,008 cis-eQTLs

70.53% done, 1,155,080,792 cis-eQTLs

70.56% done, 1,155,376,100 cis-eQTLs

70.59% done, 1,155,719,497 cis-eQTLs

70.63% done, 1,155,992,082 cis-eQTLs

70.66% done, 1,156,317,009 cis-eQTLs

70.69% done, 1,156,920,390 cis-eQTLs

70.73% done, 1,157,524,343 cis-eQTLs

70.73% done, 1,157,564,303 cis-eQTLs

70.76% done, 1,157,841,472 cis-eQTLs

70.76% done, 1,158,109,400 cis-eQTLs

70.79% done, 1,158,124,119 cis-eQTLs

70.79% done, 1,158,411,372 cis-eQTLs

70.83% done, 1,158,610,554 cis-eQTLs

70.86% done, 1,158,820,855 cis-eQTLs

70.89% done, 1,158,956,811 cis-eQTLs

70.93% done, 1,159,203,025 cis-eQTLs

70.96% done, 1,159,466,153 cis-eQTLs

71.00% done, 1,159,649,540 cis-eQTLs

71.03% done, 1,159,913,132 cis-eQTLs

71.06% done, 1,160,307,082 cis-eQTLs

71.10% done, 1,160,571,200 cis-eQTLs

71.13% done, 1,160,864,135 cis-eQTLs

71.16% done, 1,161,370,563 cis-eQTLs

71.20% done, 1,161,844,305 cis-eQTLs

71.20% done, 1,161,894,524 cis-eQTLs

71.23% done, 1,162,210,679 cis-eQTLs

71.23% done, 1,162,888,769 cis-eQTLs

71.26% done, 1,162,917,024 cis-eQTLs

71.26% done, 1,164,136,619 cis-eQTLs

71.30% done, 1,165,596,744 cis-eQTLs

71.30% done, 1,165,602,067 cis-eQTLs

71.33% done, 1,165,768,514 cis-eQTLs

71.33% done, 1,166,542,640 cis-eQTLs

71.36% done, 1,168,083,342 cis-eQTLs

71.40% done, 1,169,634,308 cis-eQTLs

71.40% done, 1,169,642,319 cis-eQTLs

71.43% done, 1,170,090,284 cis-eQTLs

71.43% done, 1,171,520,878 cis-eQTLs

71.46% done, 1,172,156,723 cis-eQTLs

71.50% done, 1,173,151,614 cis-eQTLs

71.50% done, 1,173,563,659 cis-eQTLs

71.53% done, 1,175,026,418 cis-eQTLs

71.57% done, 1,175,309,000 cis-eQTLs

71.60% done, 1,175,508,409 cis-eQTLs

71.63% done, 1,175,545,555 cis-eQTLs

71.67% done, 1,175,617,658 cis-eQTLs

71.70% done, 1,176,014,315 cis-eQTLs

71.73% done, 1,176,264,154 cis-eQTLs

71.73% done, 1,176,331,551 cis-eQTLs

71.77% done, 1,176,342,786 cis-eQTLs

71.77% done, 1,176,811,813 cis-eQTLs

71.80% done, 1,177,411,723 cis-eQTLs

71.83% done, 1,177,777,117 cis-eQTLs

71.87% done, 1,178,143,291 cis-eQTLs

71.90% done, 1,178,719,654 cis-eQTLs

71.93% done, 1,179,296,850 cis-eQTLs

71.97% done, 1,179,736,445 cis-eQTLs

72.00% done, 1,180,085,041 cis-eQTLs

72.00% done, 1,180,089,614 cis-eQTLs

72.03% done, 1,180,293,524 cis-eQTLs

72.03% done, 1,180,500,362 cis-eQTLs

72.07% done, 1,180,575,063 cis-eQTLs

72.10% done, 1,180,647,665 cis-eQTLs

72.14% done, 1,180,864,369 cis-eQTLs

72.17% done, 1,181,410,030 cis-eQTLs

72.20% done, 1,181,810,331 cis-eQTLs

72.24% done, 1,182,034,197 cis-eQTLs

72.27% done, 1,182,245,581 cis-eQTLs

72.30% done, 1,182,555,564 cis-eQTLs

72.34% done, 1,182,854,099 cis-eQTLs

72.37% done, 1,183,038,737 cis-eQTLs

72.40% done, 1,183,163,754 cis-eQTLs

72.44% done, 1,183,214,760 cis-eQTLs

72.47% done, 1,183,390,759 cis-eQTLs

72.50% done, 1,183,513,074 cis-eQTLs

72.54% done, 1,183,580,314 cis-eQTLs

72.57% done, 1,183,824,924 cis-eQTLs

72.57% done, 1,183,844,691 cis-eQTLs

72.60% done, 1,183,931,989 cis-eQTLs

72.60% done, 1,184,277,331 cis-eQTLs

72.64% done, 1,184,508,369 cis-eQTLs

72.67% done, 1,184,898,337 cis-eQTLs

72.70% done, 1,185,517,634 cis-eQTLs

72.74% done, 1,186,239,793 cis-eQTLs

72.77% done, 1,186,866,255 cis-eQTLs

72.81% done, 1,187,583,514 cis-eQTLs

72.84% done, 1,188,332,383 cis-eQTLs

72.84% done, 1,188,332,999 cis-eQTLs

72.87% done, 1,188,555,534 cis-eQTLs

72.87% done, 1,188,695,267 cis-eQTLs

72.91% done, 1,188,699,563 cis-eQTLs

72.91% done, 1,188,907,749 cis-eQTLs

72.94% done, 1,189,352,251 cis-eQTLs

72.97% done, 1,189,622,348 cis-eQTLs

73.01% done, 1,190,049,468 cis-eQTLs

73.04% done, 1,190,598,102 cis-eQTLs

73.07% done, 1,190,979,049 cis-eQTLs

73.11% done, 1,191,668,155 cis-eQTLs

73.14% done, 1,192,439,650 cis-eQTLs

73.17% done, 1,192,873,090 cis-eQTLs

73.17% done, 1,192,972,856 cis-eQTLs

73.21% done, 1,192,997,186 cis-eQTLs

73.21% done, 1,193,612,918 cis-eQTLs

73.24% done, 1,194,200,763 cis-eQTLs

73.27% done, 1,195,013,814 cis-eQTLs

73.31% done, 1,196,227,525 cis-eQTLs

73.34% done, 1,196,788,504 cis-eQTLs

73.34% done, 1,197,386,840 cis-eQTLs

73.38% done, 1,198,334,230 cis-eQTLs

73.41% done, 1,199,367,422 cis-eQTLs

73.41% done, 1,199,371,223 cis-eQTLs

73.44% done, 1,199,759,090 cis-eQTLs

73.44% done, 1,200,199,191 cis-eQTLs

73.48% done, 1,200,234,496 cis-eQTLs

73.48% done, 1,200,797,982 cis-eQTLs

73.51% done, 1,201,309,800 cis-eQTLs

73.54% done, 1,202,256,485 cis-eQTLs

73.58% done, 1,202,888,900 cis-eQTLs

73.61% done, 1,203,380,684 cis-eQTLs

73.64% done, 1,203,968,383 cis-eQTLs

73.64% done, 1,204,007,510 cis-eQTLs

73.68% done, 1,204,247,513 cis-eQTLs

73.68% done, 1,205,394,658 cis-eQTLs

73.71% done, 1,206,791,033 cis-eQTLs

73.74% done, 1,207,852,104 cis-eQTLs

73.74% done, 1,208,137,355 cis-eQTLs

73.78% done, 1,208,181,687 cis-eQTLs

73.78% done, 1,209,501,663 cis-eQTLs

73.81% done, 1,211,129,251 cis-eQTLs

73.84% done, 1,211,800,502 cis-eQTLs

73.88% done, 1,212,102,717 cis-eQTLs

73.91% done, 1,212,360,073 cis-eQTLs

73.91% done, 1,212,433,486 cis-eQTLs

73.95% done, 1,212,471,442 cis-eQTLs

73.95% done, 1,212,713,336 cis-eQTLs

73.98% done, 1,213,115,683 cis-eQTLs

74.01% done, 1,213,624,739 cis-eQTLs

74.05% done, 1,214,071,598 cis-eQTLs

74.08% done, 1,215,139,204 cis-eQTLs

74.11% done, 1,216,603,786 cis-eQTLs

74.15% done, 1,217,980,366 cis-eQTLs

74.15% done, 1,217,983,847 cis-eQTLs

74.18% done, 1,218,912,088 cis-eQTLs

74.18% done, 1,220,055,958 cis-eQTLs

74.21% done, 1,220,061,153 cis-eQTLs

74.21% done, 1,222,671,673 cis-eQTLs

74.25% done, 1,223,019,702 cis-eQTLs

74.28% done, 1,223,320,618 cis-eQTLs

74.31% done, 1,223,804,841 cis-eQTLs

74.31% done, 1,224,015,336 cis-eQTLs

74.35% done, 1,224,150,591 cis-eQTLs

74.35% done, 1,224,856,983 cis-eQTLs

74.38% done, 1,225,536,364 cis-eQTLs

74.41% done, 1,225,816,527 cis-eQTLs

74.45% done, 1,226,125,633 cis-eQTLs

74.48% done, 1,226,700,115 cis-eQTLs

74.52% done, 1,227,475,152 cis-eQTLs

74.55% done, 1,228,193,876 cis-eQTLs

74.58% done, 1,228,803,551 cis-eQTLs

74.62% done, 1,229,244,390 cis-eQTLs

74.65% done, 1,229,671,779 cis-eQTLs

74.65% done, 1,229,799,828 cis-eQTLs

74.68% done, 1,229,887,118 cis-eQTLs

74.68% done, 1,230,711,424 cis-eQTLs

74.72% done, 1,231,464,345 cis-eQTLs

74.75% done, 1,231,894,535 cis-eQTLs

74.78% done, 1,232,550,772 cis-eQTLs

74.82% done, 1,233,277,737 cis-eQTLs

74.85% done, 1,233,699,119 cis-eQTLs

74.88% done, 1,234,224,063 cis-eQTLs

74.88% done, 1,234,231,261 cis-eQTLs

74.92% done, 1,234,402,732 cis-eQTLs

74.92% done, 1,234,607,768 cis-eQTLs

74.95% done, 1,234,802,420 cis-eQTLs

74.98% done, 1,235,255,456 cis-eQTLs

75.02% done, 1,235,789,849 cis-eQTLs

75.05% done, 1,236,037,672 cis-eQTLs

75.09% done, 1,236,296,178 cis-eQTLs

75.12% done, 1,236,622,589 cis-eQTLs

75.15% done, 1,237,149,600 cis-eQTLs

75.19% done, 1,237,695,577 cis-eQTLs

75.22% done, 1,238,172,701 cis-eQTLs

75.25% done, 1,238,550,184 cis-eQTLs

75.25% done, 1,238,620,012 cis-eQTLs

75.29% done, 1,238,662,076 cis-eQTLs

75.29% done, 1,239,241,905 cis-eQTLs

75.32% done, 1,239,916,320 cis-eQTLs

75.35% done, 1,240,515,580 cis-eQTLs

75.39% done, 1,240,786,268 cis-eQTLs

75.42% done, 1,241,231,292 cis-eQTLs

75.45% done, 1,241,907,510 cis-eQTLs

75.49% done, 1,242,353,259 cis-eQTLs

75.49% done, 1,242,490,305 cis-eQTLs

75.52% done, 1,242,508,638 cis-eQTLs

75.52% done, 1,243,169,891 cis-eQTLs

75.55% done, 1,243,505,499 cis-eQTLs

75.59% done, 1,243,582,127 cis-eQTLs

75.62% done, 1,243,638,022 cis-eQTLs

75.66% done, 1,243,670,970 cis-eQTLs

75.69% done, 1,243,740,529 cis-eQTLs

75.72% done, 1,243,803,799 cis-eQTLs

75.76% done, 1,243,923,062 cis-eQTLs

75.79% done, 1,244,167,137 cis-eQTLs

75.82% done, 1,244,308,232 cis-eQTLs

75.86% done, 1,244,409,401 cis-eQTLs

75.89% done, 1,244,472,491 cis-eQTLs

75.92% done, 1,244,515,694 cis-eQTLs

75.96% done, 1,244,572,273 cis-eQTLs

75.99% done, 1,244,621,043 cis-eQTLs

76.02% done, 1,244,702,460 cis-eQTLs

76.06% done, 1,244,866,957 cis-eQTLs

76.09% done, 1,244,929,516 cis-eQTLs

76.12% done, 1,244,971,095 cis-eQTLs

76.16% done, 1,245,037,709 cis-eQTLs

76.19% done, 1,245,128,709 cis-eQTLs

76.22% done, 1,245,188,335 cis-eQTLs

76.26% done, 1,245,355,213 cis-eQTLs

76.29% done, 1,245,666,999 cis-eQTLs

76.33% done, 1,245,975,491 cis-eQTLs

76.36% done, 1,246,159,789 cis-eQTLs

76.36% done, 1,246,179,973 cis-eQTLs

76.39% done, 1,246,219,086 cis-eQTLs

76.39% done, 1,246,630,241 cis-eQTLs

76.43% done, 1,246,883,299 cis-eQTLs

76.46% done, 1,247,319,508 cis-eQTLs

76.49% done, 1,247,679,483 cis-eQTLs

76.53% done, 1,247,964,614 cis-eQTLs

76.56% done, 1,248,166,435 cis-eQTLs

76.59% done, 1,248,234,288 cis-eQTLs

76.63% done, 1,248,269,519 cis-eQTLs

76.66% done, 1,248,312,294 cis-eQTLs

76.69% done, 1,248,390,106 cis-eQTLs

76.73% done, 1,248,462,183 cis-eQTLs

76.76% done, 1,248,565,036 cis-eQTLs

76.79% done, 1,248,618,594 cis-eQTLs

76.83% done, 1,248,694,388 cis-eQTLs

76.86% done, 1,248,807,214 cis-eQTLs

76.90% done, 1,248,877,022 cis-eQTLs

76.93% done, 1,248,958,595 cis-eQTLs

76.96% done, 1,249,082,999 cis-eQTLs

77.00% done, 1,249,268,229 cis-eQTLs

77.03% done, 1,249,371,420 cis-eQTLs

77.06% done, 1,249,573,027 cis-eQTLs

77.10% done, 1,249,971,921 cis-eQTLs

77.13% done, 1,250,417,276 cis-eQTLs

77.13% done, 1,250,523,376 cis-eQTLs

77.16% done, 1,250,644,028 cis-eQTLs

77.16% done, 1,250,867,442 cis-eQTLs

77.20% done, 1,251,275,409 cis-eQTLs

77.23% done, 1,252,062,547 cis-eQTLs

77.26% done, 1,252,966,733 cis-eQTLs

77.30% done, 1,253,851,141 cis-eQTLs

77.33% done, 1,254,300,695 cis-eQTLs

77.36% done, 1,254,608,195 cis-eQTLs

77.40% done, 1,254,882,767 cis-eQTLs

77.40% done, 1,255,111,533 cis-eQTLs

77.43% done, 1,255,136,730 cis-eQTLs

77.43% done, 1,255,338,947 cis-eQTLs

77.47% done, 1,255,408,201 cis-eQTLs

77.50% done, 1,255,503,659 cis-eQTLs

77.53% done, 1,255,761,617 cis-eQTLs

77.57% done, 1,256,186,164 cis-eQTLs

77.60% done, 1,256,450,269 cis-eQTLs

77.63% done, 1,256,748,084 cis-eQTLs

77.67% done, 1,257,147,665 cis-eQTLs

77.70% done, 1,257,974,755 cis-eQTLs

77.73% done, 1,259,400,075 cis-eQTLs

77.77% done, 1,260,317,511 cis-eQTLs

77.77% done, 1,260,645,292 cis-eQTLs

77.80% done, 1,260,736,880 cis-eQTLs

77.80% done, 1,262,155,256 cis-eQTLs

77.83% done, 1,264,563,745 cis-eQTLs

77.83% done, 1,264,767,634 cis-eQTLs

77.87% done, 1,265,468,309 cis-eQTLs

77.87% done, 1,266,813,513 cis-eQTLs

77.90% done, 1,267,345,027 cis-eQTLs

77.93% done, 1,268,005,490 cis-eQTLs

77.97% done, 1,269,329,220 cis-eQTLs

77.97% done, 1,269,330,671 cis-eQTLs

78.00% done, 1,270,035,708 cis-eQTLs

78.00% done, 1,270,303,967 cis-eQTLs

78.03% done, 1,270,373,915 cis-eQTLs

78.03% done, 1,271,165,847 cis-eQTLs

78.07% done, 1,272,753,283 cis-eQTLs

78.10% done, 1,274,322,514 cis-eQTLs

78.10% done, 1,274,412,320 cis-eQTLs

78.14% done, 1,275,165,479 cis-eQTLs

78.14% done, 1,275,800,232 cis-eQTLs

78.17% done, 1,276,030,503 cis-eQTLs

78.20% done, 1,276,160,188 cis-eQTLs

78.24% done, 1,276,267,279 cis-eQTLs

78.27% done, 1,276,372,124 cis-eQTLs

78.30% done, 1,276,610,309 cis-eQTLs

78.34% done, 1,276,940,987 cis-eQTLs

78.37% done, 1,277,376,043 cis-eQTLs

78.40% done, 1,277,699,714 cis-eQTLs

78.44% done, 1,277,957,571 cis-eQTLs

78.47% done, 1,278,402,098 cis-eQTLs

78.50% done, 1,278,999,682 cis-eQTLs

78.54% done, 1,279,353,971 cis-eQTLs

78.54% done, 1,279,562,565 cis-eQTLs

78.57% done, 1,279,573,764 cis-eQTLs

78.57% done, 1,280,145,786 cis-eQTLs

78.60% done, 1,280,441,296 cis-eQTLs

78.64% done, 1,280,793,020 cis-eQTLs

78.67% done, 1,280,944,544 cis-eQTLs

78.71% done, 1,280,979,701 cis-eQTLs

78.74% done, 1,281,045,729 cis-eQTLs

78.77% done, 1,281,122,294 cis-eQTLs

78.81% done, 1,281,157,453 cis-eQTLs

78.84% done, 1,281,205,892 cis-eQTLs

78.87% done, 1,281,377,330 cis-eQTLs

78.91% done, 1,281,544,897 cis-eQTLs

78.94% done, 1,281,616,517 cis-eQTLs

78.97% done, 1,281,714,455 cis-eQTLs

79.01% done, 1,281,772,733 cis-eQTLs

79.04% done, 1,281,845,989 cis-eQTLs

79.07% done, 1,282,582,163 cis-eQTLs

79.11% done, 1,283,232,095 cis-eQTLs

79.11% done, 1,283,366,292 cis-eQTLs

79.14% done, 1,283,448,526 cis-eQTLs

79.14% done, 1,284,056,884 cis-eQTLs

79.17% done, 1,284,643,094 cis-eQTLs

79.21% done, 1,285,082,190 cis-eQTLs

79.24% done, 1,285,707,134 cis-eQTLs

79.28% done, 1,286,443,256 cis-eQTLs

79.31% done, 1,286,928,632 cis-eQTLs

79.34% done, 1,287,427,956 cis-eQTLs

79.38% done, 1,287,778,304 cis-eQTLs

79.38% done, 1,287,833,013 cis-eQTLs

79.41% done, 1,287,898,459 cis-eQTLs

79.41% done, 1,288,398,716 cis-eQTLs

79.44% done, 1,288,995,207 cis-eQTLs

79.48% done, 1,289,752,294 cis-eQTLs

79.51% done, 1,290,300,556 cis-eQTLs

79.54% done, 1,290,571,924 cis-eQTLs

79.58% done, 1,291,277,596 cis-eQTLs

79.58% done, 1,291,353,278 cis-eQTLs

79.61% done, 1,291,627,241 cis-eQTLs

79.61% done, 1,292,377,095 cis-eQTLs

79.64% done, 1,292,713,710 cis-eQTLs

79.68% done, 1,293,362,698 cis-eQTLs

79.71% done, 1,294,340,626 cis-eQTLs

79.74% done, 1,295,220,019 cis-eQTLs

79.74% done, 1,295,339,077 cis-eQTLs

79.78% done, 1,295,485,197 cis-eQTLs

79.78% done, 1,296,051,682 cis-eQTLs

79.81% done, 1,296,634,745 cis-eQTLs

79.85% done, 1,297,122,482 cis-eQTLs

79.88% done, 1,298,103,080 cis-eQTLs

79.91% done, 1,299,215,719 cis-eQTLs

79.95% done, 1,299,655,561 cis-eQTLs

79.95% done, 1,300,408,353 cis-eQTLs

79.98% done, 1,301,293,954 cis-eQTLs

80.01% done, 1,302,506,997 cis-eQTLs

80.05% done, 1,303,257,140 cis-eQTLs

80.08% done, 1,303,542,575 cis-eQTLs

80.11% done, 1,303,715,429 cis-eQTLs

80.15% done, 1,303,947,582 cis-eQTLs

80.15% done, 1,304,059,381 cis-eQTLs

80.18% done, 1,304,103,083 cis-eQTLs

80.18% done, 1,304,311,395 cis-eQTLs

80.21% done, 1,304,378,482 cis-eQTLs

80.25% done, 1,304,449,379 cis-eQTLs

80.28% done, 1,304,519,917 cis-eQTLs

80.31% done, 1,304,762,485 cis-eQTLs

80.35% done, 1,304,868,712 cis-eQTLs

80.38% done, 1,305,010,848 cis-eQTLs

80.42% done, 1,305,570,130 cis-eQTLs

80.45% done, 1,306,217,624 cis-eQTLs

80.48% done, 1,306,973,833 cis-eQTLs

80.52% done, 1,307,904,258 cis-eQTLs

80.52% done, 1,307,911,412 cis-eQTLs

80.55% done, 1,308,283,667 cis-eQTLs

80.55% done, 1,308,709,784 cis-eQTLs

80.58% done, 1,308,714,482 cis-eQTLs

80.58% done, 1,309,696,379 cis-eQTLs

80.62% done, 1,310,589,193 cis-eQTLs

80.65% done, 1,311,590,151 cis-eQTLs

80.68% done, 1,312,522,307 cis-eQTLs

80.72% done, 1,313,439,675 cis-eQTLs

80.72% done, 1,313,457,769 cis-eQTLs

80.75% done, 1,313,813,634 cis-eQTLs

80.75% done, 1,314,344,936 cis-eQTLs

80.78% done, 1,314,819,913 cis-eQTLs

80.82% done, 1,315,013,329 cis-eQTLs

80.85% done, 1,315,458,446 cis-eQTLs

80.88% done, 1,316,749,082 cis-eQTLs

80.92% done, 1,317,826,579 cis-eQTLs

80.92% done, 1,318,815,443 cis-eQTLs

80.95% done, 1,318,877,099 cis-eQTLs

80.95% done, 1,320,329,315 cis-eQTLs

80.98% done, 1,321,555,352 cis-eQTLs

80.99% done, 1,321,813,614 cis-eQTLs

81.02% done, 1,321,957,396 cis-eQTLs

81.02% done, 1,323,442,545 cis-eQTLs

81.05% done, 1,325,504,304 cis-eQTLs

81.05% done, 1,325,578,159 cis-eQTLs

81.09% done, 1,326,268,267 cis-eQTLs

81.09% done, 1,327,016,002 cis-eQTLs

81.12% done, 1,327,462,403 cis-eQTLs

81.15% done, 1,327,662,250 cis-eQTLs

81.19% done, 1,327,946,688 cis-eQTLs

81.22% done, 1,328,219,923 cis-eQTLs

81.25% done, 1,328,388,410 cis-eQTLs

81.29% done, 1,328,666,214 cis-eQTLs

81.32% done, 1,329,723,315 cis-eQTLs

81.35% done, 1,330,310,224 cis-eQTLs

81.39% done, 1,330,747,008 cis-eQTLs

81.39% done, 1,330,754,106 cis-eQTLs

81.42% done, 1,330,910,200 cis-eQTLs

81.42% done, 1,331,256,054 cis-eQTLs

81.45% done, 1,331,256,177 cis-eQTLs

81.45% done, 1,331,721,341 cis-eQTLs

81.49% done, 1,332,150,500 cis-eQTLs

81.52% done, 1,332,849,857 cis-eQTLs

81.55% done, 1,333,262,293 cis-eQTLs

81.59% done, 1,333,729,099 cis-eQTLs

81.62% done, 1,334,266,132 cis-eQTLs

81.66% done, 1,334,820,512 cis-eQTLs

81.69% done, 1,335,057,002 cis-eQTLs

81.69% done, 1,335,065,306 cis-eQTLs

81.72% done, 1,335,180,252 cis-eQTLs

81.72% done, 1,335,532,647 cis-eQTLs

81.76% done, 1,335,829,397 cis-eQTLs

81.79% done, 1,336,285,745 cis-eQTLs

81.82% done, 1,336,944,797 cis-eQTLs

81.86% done, 1,338,439,711 cis-eQTLs

81.89% done, 1,339,040,258 cis-eQTLs

81.89% done, 1,339,638,773 cis-eQTLs

81.92% done, 1,340,600,999 cis-eQTLs

81.96% done, 1,341,467,423 cis-eQTLs

81.99% done, 1,341,801,285 cis-eQTLs

82.02% done, 1,341,900,532 cis-eQTLs

82.02% done, 1,341,969,184 cis-eQTLs

82.06% done, 1,341,990,876 cis-eQTLs

82.06% done, 1,342,476,763 cis-eQTLs

82.09% done, 1,342,907,207 cis-eQTLs

82.12% done, 1,343,401,206 cis-eQTLs

82.16% done, 1,344,097,841 cis-eQTLs

82.19% done, 1,344,827,332 cis-eQTLs

82.23% done, 1,345,039,953 cis-eQTLs

82.26% done, 1,345,162,941 cis-eQTLs

82.29% done, 1,345,345,119 cis-eQTLs

82.33% done, 1,345,748,638 cis-eQTLs

82.33% done, 1,345,819,356 cis-eQTLs

82.36% done, 1,345,892,051 cis-eQTLs

82.36% done, 1,346,230,324 cis-eQTLs

82.39% done, 1,346,862,527 cis-eQTLs

82.43% done, 1,347,419,948 cis-eQTLs

82.46% done, 1,348,157,988 cis-eQTLs

82.49% done, 1,348,762,990 cis-eQTLs

82.53% done, 1,349,191,756 cis-eQTLs

82.56% done, 1,349,680,962 cis-eQTLs

82.59% done, 1,350,074,665 cis-eQTLs

82.59% done, 1,350,608,608 cis-eQTLs

82.63% done, 1,350,608,995 cis-eQTLs

82.63% done, 1,351,480,403 cis-eQTLs

82.66% done, 1,352,543,874 cis-eQTLs

82.69% done, 1,353,443,120 cis-eQTLs

82.69% done, 1,353,497,099 cis-eQTLs

82.73% done, 1,353,855,568 cis-eQTLs

82.73% done, 1,354,399,373 cis-eQTLs

82.76% done, 1,355,271,942 cis-eQTLs

82.80% done, 1,356,189,898 cis-eQTLs

82.83% done, 1,356,959,775 cis-eQTLs

82.83% done, 1,356,962,173 cis-eQTLs

82.86% done, 1,357,269,577 cis-eQTLs

82.86% done, 1,357,597,609 cis-eQTLs

82.90% done, 1,358,486,308 cis-eQTLs

82.93% done, 1,359,820,697 cis-eQTLs

82.93% done, 1,359,900,300 cis-eQTLs

82.96% done, 1,359,992,955 cis-eQTLs

82.96% done, 1,360,559,111 cis-eQTLs

83.00% done, 1,361,409,260 cis-eQTLs

83.03% done, 1,362,549,583 cis-eQTLs

83.06% done, 1,363,376,968 cis-eQTLs

83.10% done, 1,363,994,072 cis-eQTLs

83.10% done, 1,364,009,320 cis-eQTLs

83.13% done, 1,364,356,375 cis-eQTLs

83.13% done, 1,364,838,058 cis-eQTLs

83.16% done, 1,365,282,870 cis-eQTLs

83.20% done, 1,365,883,352 cis-eQTLs

83.23% done, 1,366,380,552 cis-eQTLs

83.26% done, 1,367,145,176 cis-eQTLs

83.30% done, 1,367,639,159 cis-eQTLs

83.33% done, 1,367,773,650 cis-eQTLs

83.37% done, 1,368,000,891 cis-eQTLs

83.37% done, 1,368,025,465 cis-eQTLs

83.40% done, 1,368,210,554 cis-eQTLs

83.40% done, 1,369,035,409 cis-eQTLs

83.43% done, 1,370,400,430 cis-eQTLs

83.47% done, 1,371,649,812 cis-eQTLs

83.50% done, 1,372,459,244 cis-eQTLs

83.53% done, 1,372,878,361 cis-eQTLs

83.53% done, 1,373,043,115 cis-eQTLs

83.57% done, 1,373,155,117 cis-eQTLs

83.57% done, 1,373,944,715 cis-eQTLs

83.60% done, 1,374,563,481 cis-eQTLs

83.63% done, 1,374,911,452 cis-eQTLs

83.67% done, 1,375,211,727 cis-eQTLs

83.70% done, 1,375,540,600 cis-eQTLs

83.73% done, 1,376,190,435 cis-eQTLs

83.77% done, 1,376,413,397 cis-eQTLs

83.80% done, 1,376,820,806 cis-eQTLs

83.83% done, 1,377,671,059 cis-eQTLs

83.87% done, 1,378,323,531 cis-eQTLs

83.87% done, 1,378,470,695 cis-eQTLs

83.90% done, 1,378,588,269 cis-eQTLs

83.90% done, 1,379,137,244 cis-eQTLs

83.94% done, 1,380,198,584 cis-eQTLs

83.97% done, 1,381,305,655 cis-eQTLs

84.00% done, 1,382,923,567 cis-eQTLs

84.00% done, 1,383,827,676 cis-eQTLs

84.04% done, 1,384,515,311 cis-eQTLs

84.04% done, 1,387,853,376 cis-eQTLs

84.04% done, 1,387,934,784 cis-eQTLs

84.07% done, 1,389,900,462 cis-eQTLs

84.07% done, 1,391,642,350 cis-eQTLs

84.10% done, 1,391,823,190 cis-eQTLs

84.10% done, 1,394,059,567 cis-eQTLs

84.10% done, 1,394,480,102 cis-eQTLs

84.14% done, 1,394,913,047 cis-eQTLs

84.14% done, 1,396,679,150 cis-eQTLs

84.17% done, 1,398,304,580 cis-eQTLs

84.17% done, 1,398,333,564 cis-eQTLs

84.20% done, 1,398,943,568 cis-eQTLs

84.20% done, 1,399,104,936 cis-eQTLs

84.24% done, 1,399,112,485 cis-eQTLs

84.24% done, 1,399,336,056 cis-eQTLs

84.27% done, 1,399,544,936 cis-eQTLs

84.30% done, 1,399,713,945 cis-eQTLs

84.34% done, 1,399,915,885 cis-eQTLs

84.37% done, 1,400,124,195 cis-eQTLs

84.40% done, 1,400,318,879 cis-eQTLs

84.44% done, 1,400,867,978 cis-eQTLs

84.47% done, 1,401,724,911 cis-eQTLs

84.51% done, 1,402,167,628 cis-eQTLs

84.54% done, 1,402,609,833 cis-eQTLs

84.57% done, 1,403,543,982 cis-eQTLs

84.61% done, 1,404,862,628 cis-eQTLs

84.64% done, 1,405,721,019 cis-eQTLs

84.64% done, 1,405,855,645 cis-eQTLs

84.67% done, 1,405,973,934 cis-eQTLs

84.67% done, 1,406,392,381 cis-eQTLs

84.71% done, 1,406,707,472 cis-eQTLs

84.74% done, 1,407,119,063 cis-eQTLs

84.77% done, 1,407,761,004 cis-eQTLs

84.81% done, 1,408,147,884 cis-eQTLs

84.84% done, 1,408,522,717 cis-eQTLs

84.87% done, 1,408,956,808 cis-eQTLs

84.91% done, 1,409,672,307 cis-eQTLs

84.94% done, 1,410,036,095 cis-eQTLs

84.94% done, 1,410,269,978 cis-eQTLs

84.97% done, 1,410,279,166 cis-eQTLs

84.97% done, 1,410,900,503 cis-eQTLs

85.01% done, 1,411,691,765 cis-eQTLs

85.04% done, 1,412,305,306 cis-eQTLs

85.08% done, 1,412,622,174 cis-eQTLs

85.11% done, 1,412,758,300 cis-eQTLs

85.14% done, 1,413,276,105 cis-eQTLs

85.14% done, 1,413,282,029 cis-eQTLs

85.18% done, 1,413,580,176 cis-eQTLs

85.18% done, 1,414,145,882 cis-eQTLs

85.21% done, 1,415,250,639 cis-eQTLs

85.21% done, 1,415,251,264 cis-eQTLs

85.24% done, 1,415,657,901 cis-eQTLs

85.24% done, 1,416,755,040 cis-eQTLs

85.28% done, 1,416,987,029 cis-eQTLs

85.31% done, 1,417,499,442 cis-eQTLs

85.31% done, 1,417,522,325 cis-eQTLs

85.34% done, 1,417,680,248 cis-eQTLs

85.34% done, 1,418,390,280 cis-eQTLs

85.38% done, 1,419,222,555 cis-eQTLs

85.41% done, 1,419,557,213 cis-eQTLs

85.44% done, 1,419,930,095 cis-eQTLs

85.48% done, 1,420,487,448 cis-eQTLs

85.51% done, 1,421,024,938 cis-eQTLs

85.54% done, 1,421,634,234 cis-eQTLs

85.54% done, 1,421,679,675 cis-eQTLs

85.58% done, 1,421,814,153 cis-eQTLs

85.58% done, 1,422,809,994 cis-eQTLs

85.61% done, 1,424,351,650 cis-eQTLs

85.65% done, 1,425,593,169 cis-eQTLs

85.68% done, 1,426,024,208 cis-eQTLs

85.71% done, 1,426,116,257 cis-eQTLs

85.75% done, 1,426,145,847 cis-eQTLs

85.78% done, 1,426,264,284 cis-eQTLs

85.78% done, 1,426,273,942 cis-eQTLs

85.81% done, 1,426,288,623 cis-eQTLs

85.81% done, 1,426,350,746 cis-eQTLs

85.85% done, 1,426,427,288 cis-eQTLs

85.88% done, 1,426,622,052 cis-eQTLs

85.91% done, 1,426,976,394 cis-eQTLs

85.95% done, 1,428,217,694 cis-eQTLs

85.95% done, 1,428,459,318 cis-eQTLs

85.98% done, 1,428,480,681 cis-eQTLs

85.98% done, 1,429,604,710 cis-eQTLs

86.01% done, 1,430,557,711 cis-eQTLs

86.05% done, 1,431,254,803 cis-eQTLs

86.05% done, 1,431,546,848 cis-eQTLs

86.08% done, 1,431,591,709 cis-eQTLs

86.08% done, 1,432,293,207 cis-eQTLs

86.11% done, 1,432,697,979 cis-eQTLs

86.15% done, 1,433,618,419 cis-eQTLs

86.18% done, 1,434,456,714 cis-eQTLs

86.22% done, 1,434,649,002 cis-eQTLs

86.25% done, 1,434,985,371 cis-eQTLs

86.28% done, 1,435,485,800 cis-eQTLs

86.32% done, 1,435,955,364 cis-eQTLs

86.32% done, 1,435,955,676 cis-eQTLs

86.35% done, 1,436,289,500 cis-eQTLs

86.35% done, 1,436,353,573 cis-eQTLs

86.38% done, 1,436,472,141 cis-eQTLs

86.38% done, 1,436,727,224 cis-eQTLs

86.42% done, 1,436,732,762 cis-eQTLs

86.42% done, 1,437,165,733 cis-eQTLs

86.45% done, 1,437,541,281 cis-eQTLs

86.48% done, 1,438,173,342 cis-eQTLs

86.52% done, 1,439,248,064 cis-eQTLs

86.55% done, 1,440,258,392 cis-eQTLs

86.58% done, 1,440,751,962 cis-eQTLs

86.62% done, 1,441,062,897 cis-eQTLs

86.65% done, 1,441,466,816 cis-eQTLs

86.68% done, 1,442,545,903 cis-eQTLs

86.68% done, 1,442,548,648 cis-eQTLs

86.72% done, 1,443,700,685 cis-eQTLs

86.72% done, 1,444,071,725 cis-eQTLs

86.75% done, 1,444,578,970 cis-eQTLs

86.75% done, 1,445,653,927 cis-eQTLs

86.79% done, 1,445,660,330 cis-eQTLs

86.79% done, 1,447,610,834 cis-eQTLs

86.82% done, 1,449,441,841 cis-eQTLs

86.85% done, 1,450,771,891 cis-eQTLs

86.85% done, 1,450,959,414 cis-eQTLs

86.89% done, 1,451,553,445 cis-eQTLs

86.89% done, 1,452,518,894 cis-eQTLs

86.92% done, 1,452,521,553 cis-eQTLs

86.92% done, 1,454,411,769 cis-eQTLs

86.95% done, 1,456,356,492 cis-eQTLs

86.95% done, 1,456,367,971 cis-eQTLs

86.99% done, 1,457,879,869 cis-eQTLs

86.99% done, 1,459,251,386 cis-eQTLs

87.02% done, 1,459,475,405 cis-eQTLs

87.02% done, 1,462,279,702 cis-eQTLs

87.02% done, 1,462,294,622 cis-eQTLs

87.05% done, 1,463,578,202 cis-eQTLs

87.05% done, 1,463,854,571 cis-eQTLs

87.09% done, 1,465,551,569 cis-eQTLs

87.12% done, 1,467,864,070 cis-eQTLs

87.15% done, 1,469,227,125 cis-eQTLs

87.15% done, 1,469,910,555 cis-eQTLs

87.19% done, 1,469,946,184 cis-eQTLs

87.19% done, 1,471,088,031 cis-eQTLs

87.22% done, 1,472,350,174 cis-eQTLs

87.25% done, 1,473,865,099 cis-eQTLs

87.25% done, 1,473,982,526 cis-eQTLs

87.29% done, 1,474,558,647 cis-eQTLs

87.29% done, 1,475,646,573 cis-eQTLs

87.32% done, 1,476,416,512 cis-eQTLs

87.36% done, 1,477,304,977 cis-eQTLs

87.39% done, 1,479,054,787 cis-eQTLs

87.39% done, 1,479,726,782 cis-eQTLs

87.42% done, 1,479,898,243 cis-eQTLs

87.42% done, 1,481,813,096 cis-eQTLs

87.46% done, 1,482,709,233 cis-eQTLs

87.49% done, 1,483,313,795 cis-eQTLs

87.49% done, 1,483,477,338 cis-eQTLs

87.52% done, 1,483,583,324 cis-eQTLs

87.52% done, 1,484,025,143 cis-eQTLs

87.56% done, 1,484,324,590 cis-eQTLs

87.59% done, 1,484,690,094 cis-eQTLs

87.62% done, 1,485,029,473 cis-eQTLs

87.66% done, 1,485,400,076 cis-eQTLs

87.69% done, 1,485,801,957 cis-eQTLs

87.72% done, 1,486,285,556 cis-eQTLs

87.76% done, 1,487,057,497 cis-eQTLs

87.79% done, 1,487,905,708 cis-eQTLs

87.79% done, 1,488,367,064 cis-eQTLs

87.82% done, 1,488,379,212 cis-eQTLs

87.82% done, 1,489,314,930 cis-eQTLs

87.86% done, 1,489,997,421 cis-eQTLs

87.89% done, 1,490,616,911 cis-eQTLs

87.93% done, 1,490,739,397 cis-eQTLs

87.93% done, 1,491,017,248 cis-eQTLs

87.96% done, 1,491,026,176 cis-eQTLs

87.96% done, 1,492,226,467 cis-eQTLs

87.99% done, 1,492,906,092 cis-eQTLs

88.03% done, 1,493,202,890 cis-eQTLs

88.03% done, 1,493,600,026 cis-eQTLs

88.06% done, 1,494,108,256 cis-eQTLs

88.09% done, 1,494,415,145 cis-eQTLs

88.13% done, 1,494,960,324 cis-eQTLs

88.16% done, 1,495,859,968 cis-eQTLs

88.19% done, 1,496,684,584 cis-eQTLs

88.23% done, 1,496,991,092 cis-eQTLs

88.23% done, 1,497,516,877 cis-eQTLs

88.26% done, 1,498,829,047 cis-eQTLs

88.29% done, 1,499,948,272 cis-eQTLs

88.29% done, 1,500,284,586 cis-eQTLs

88.33% done, 1,500,362,372 cis-eQTLs

88.33% done, 1,501,660,206 cis-eQTLs

88.36% done, 1,503,301,516 cis-eQTLs

88.36% done, 1,503,434,768 cis-eQTLs

88.39% done, 1,503,603,743 cis-eQTLs

88.39% done, 1,505,029,703 cis-eQTLs

88.43% done, 1,506,445,391 cis-eQTLs

88.46% done, 1,507,280,999 cis-eQTLs

88.46% done, 1,507,307,051 cis-eQTLs

88.50% done, 1,507,768,146 cis-eQTLs

88.50% done, 1,507,918,527 cis-eQTLs

88.53% done, 1,508,814,115 cis-eQTLs

88.56% done, 1,510,500,894 cis-eQTLs

88.60% done, 1,511,501,895 cis-eQTLs

88.60% done, 1,512,090,670 cis-eQTLs

88.63% done, 1,512,093,033 cis-eQTLs

88.63% done, 1,513,893,598 cis-eQTLs

88.66% done, 1,514,358,543 cis-eQTLs

88.70% done, 1,514,489,448 cis-eQTLs

88.73% done, 1,514,592,931 cis-eQTLs

88.76% done, 1,514,741,525 cis-eQTLs

88.80% done, 1,515,208,251 cis-eQTLs

88.80% done, 1,515,214,430 cis-eQTLs

88.83% done, 1,515,311,407 cis-eQTLs

88.83% done, 1,515,731,151 cis-eQTLs

88.86% done, 1,516,705,689 cis-eQTLs

88.90% done, 1,517,574,869 cis-eQTLs

88.93% done, 1,518,148,210 cis-eQTLs

88.93% done, 1,518,191,809 cis-eQTLs

88.96% done, 1,518,292,725 cis-eQTLs

88.96% done, 1,518,693,419 cis-eQTLs

89.00% done, 1,519,664,087 cis-eQTLs

89.03% done, 1,520,165,568 cis-eQTLs

89.07% done, 1,520,674,560 cis-eQTLs

89.10% done, 1,521,380,836 cis-eQTLs

89.10% done, 1,521,415,808 cis-eQTLs

89.13% done, 1,521,526,299 cis-eQTLs

89.13% done, 1,522,089,854 cis-eQTLs

89.17% done, 1,522,551,781 cis-eQTLs

89.20% done, 1,522,860,034 cis-eQTLs

89.23% done, 1,523,024,168 cis-eQTLs

89.27% done, 1,523,345,363 cis-eQTLs

89.30% done, 1,524,047,141 cis-eQTLs

89.33% done, 1,524,953,702 cis-eQTLs

89.37% done, 1,525,927,861 cis-eQTLs

89.37% done, 1,526,243,136 cis-eQTLs

89.40% done, 1,526,423,419 cis-eQTLs

89.40% done, 1,528,232,227 cis-eQTLs

89.43% done, 1,529,806,627 cis-eQTLs

89.43% done, 1,530,088,526 cis-eQTLs

89.47% done, 1,530,390,345 cis-eQTLs

89.47% done, 1,531,721,160 cis-eQTLs

89.50% done, 1,533,188,394 cis-eQTLs

89.53% done, 1,534,962,462 cis-eQTLs

89.53% done, 1,535,029,072 cis-eQTLs

89.57% done, 1,535,795,289 cis-eQTLs

89.57% done, 1,536,724,598 cis-eQTLs

89.60% done, 1,536,747,268 cis-eQTLs

89.60% done, 1,538,741,208 cis-eQTLs

89.64% done, 1,540,649,590 cis-eQTLs

89.64% done, 1,541,246,957 cis-eQTLs

89.67% done, 1,541,971,840 cis-eQTLs

89.67% done, 1,544,444,697 cis-eQTLs

89.70% done, 1,546,527,587 cis-eQTLs

89.70% done, 1,547,638,989 cis-eQTLs

89.74% done, 1,547,739,202 cis-eQTLs

89.74% done, 1,550,125,858 cis-eQTLs

89.77% done, 1,550,636,408 cis-eQTLs

89.80% done, 1,551,050,961 cis-eQTLs

89.84% done, 1,551,124,193 cis-eQTLs

89.87% done, 1,551,413,046 cis-eQTLs

89.87% done, 1,551,417,211 cis-eQTLs

89.90% done, 1,551,743,926 cis-eQTLs

89.90% done, 1,552,169,429 cis-eQTLs

89.94% done, 1,552,180,630 cis-eQTLs

89.94% done, 1,552,709,111 cis-eQTLs

89.97% done, 1,552,864,655 cis-eQTLs

90.00% done, 1,553,254,789 cis-eQTLs

90.04% done, 1,553,600,227 cis-eQTLs

90.07% done, 1,553,940,192 cis-eQTLs

90.10% done, 1,554,262,235 cis-eQTLs

90.14% done, 1,554,845,767 cis-eQTLs

90.17% done, 1,555,485,938 cis-eQTLs

90.21% done, 1,556,023,178 cis-eQTLs

90.24% done, 1,556,443,671 cis-eQTLs

90.27% done, 1,556,907,617 cis-eQTLs

90.27% done, 1,557,038,694 cis-eQTLs

90.31% done, 1,557,274,928 cis-eQTLs

90.31% done, 1,557,892,148 cis-eQTLs

90.34% done, 1,558,641,761 cis-eQTLs

90.37% done, 1,559,059,032 cis-eQTLs

90.41% done, 1,559,155,264 cis-eQTLs

90.44% done, 1,559,522,494 cis-eQTLs

90.47% done, 1,560,050,062 cis-eQTLs

90.51% done, 1,560,521,583 cis-eQTLs

90.54% done, 1,560,720,976 cis-eQTLs

90.57% done, 1,560,879,699 cis-eQTLs

90.57% done, 1,561,117,802 cis-eQTLs

90.61% done, 1,561,285,224 cis-eQTLs

90.64% done, 1,561,399,661 cis-eQTLs

90.67% done, 1,561,436,461 cis-eQTLs

90.71% done, 1,561,530,396 cis-eQTLs

90.74% done, 1,561,976,510 cis-eQTLs

90.78% done, 1,562,347,223 cis-eQTLs

90.81% done, 1,562,546,870 cis-eQTLs

90.84% done, 1,563,025,890 cis-eQTLs

90.88% done, 1,563,528,497 cis-eQTLs

90.91% done, 1,563,933,204 cis-eQTLs

90.94% done, 1,564,035,608 cis-eQTLs

90.98% done, 1,564,121,611 cis-eQTLs

91.01% done, 1,564,197,355 cis-eQTLs

91.04% done, 1,564,267,608 cis-eQTLs

91.08% done, 1,564,377,036 cis-eQTLs

91.11% done, 1,564,470,500 cis-eQTLs

91.14% done, 1,564,578,227 cis-eQTLs

91.14% done, 1,564,632,103 cis-eQTLs

91.18% done, 1,564,661,871 cis-eQTLs

91.18% done, 1,565,003,395 cis-eQTLs

91.21% done, 1,565,644,029 cis-eQTLs

91.24% done, 1,566,105,967 cis-eQTLs

91.28% done, 1,566,715,102 cis-eQTLs

91.31% done, 1,567,352,813 cis-eQTLs

91.35% done, 1,567,933,161 cis-eQTLs

91.38% done, 1,568,452,432 cis-eQTLs

91.41% done, 1,568,595,569 cis-eQTLs

91.45% done, 1,568,704,296 cis-eQTLs

91.48% done, 1,568,775,315 cis-eQTLs

91.51% done, 1,568,985,419 cis-eQTLs

91.51% done, 1,569,028,636 cis-eQTLs

91.55% done, 1,569,033,407 cis-eQTLs

91.55% done, 1,569,432,174 cis-eQTLs

91.58% done, 1,569,770,768 cis-eQTLs

91.61% done, 1,570,420,252 cis-eQTLs

91.65% done, 1,571,188,711 cis-eQTLs

91.68% done, 1,571,885,841 cis-eQTLs

91.71% done, 1,572,377,553 cis-eQTLs

91.75% done, 1,572,542,368 cis-eQTLs

91.78% done, 1,572,872,428 cis-eQTLs

91.81% done, 1,573,400,616 cis-eQTLs

91.81% done, 1,573,465,478 cis-eQTLs

91.85% done, 1,573,572,270 cis-eQTLs

91.85% done, 1,574,219,822 cis-eQTLs

91.88% done, 1,574,445,276 cis-eQTLs

91.91% done, 1,574,504,869 cis-eQTLs

91.95% done, 1,574,600,417 cis-eQTLs

91.98% done, 1,574,708,922 cis-eQTLs

92.02% done, 1,574,826,365 cis-eQTLs

92.05% done, 1,574,986,916 cis-eQTLs

92.08% done, 1,575,222,389 cis-eQTLs

92.12% done, 1,575,539,433 cis-eQTLs

92.15% done, 1,575,589,186 cis-eQTLs

92.18% done, 1,575,634,954 cis-eQTLs

92.22% done, 1,575,785,296 cis-eQTLs

92.25% done, 1,575,938,109 cis-eQTLs

92.28% done, 1,576,358,005 cis-eQTLs

92.32% done, 1,576,937,324 cis-eQTLs

92.35% done, 1,577,277,156 cis-eQTLs

92.38% done, 1,577,898,960 cis-eQTLs

92.38% done, 1,578,061,477 cis-eQTLs

92.42% done, 1,578,323,130 cis-eQTLs

92.42% done, 1,578,753,416 cis-eQTLs

92.45% done, 1,578,757,651 cis-eQTLs

92.45% done, 1,579,056,947 cis-eQTLs

92.48% done, 1,579,591,835 cis-eQTLs

92.52% done, 1,580,605,696 cis-eQTLs

92.55% done, 1,582,116,910 cis-eQTLs

92.59% done, 1,583,139,828 cis-eQTLs

92.59% done, 1,583,433,732 cis-eQTLs

92.62% done, 1,584,298,788 cis-eQTLs

92.62% done, 1,586,045,113 cis-eQTLs

92.65% done, 1,586,120,848 cis-eQTLs

92.65% done, 1,588,845,129 cis-eQTLs

92.65% done, 1,589,009,578 cis-eQTLs

92.69% done, 1,589,720,028 cis-eQTLs

92.69% done, 1,591,477,238 cis-eQTLs

92.72% done, 1,593,579,543 cis-eQTLs

92.75% done, 1,595,186,227 cis-eQTLs

92.75% done, 1,595,784,367 cis-eQTLs

92.79% done, 1,595,920,495 cis-eQTLs

92.79% done, 1,597,791,547 cis-eQTLs

92.82% done, 1,599,426,281 cis-eQTLs

92.85% done, 1,600,316,841 cis-eQTLs

92.85% done, 1,600,949,566 cis-eQTLs

92.89% done, 1,602,029,261 cis-eQTLs

92.92% done, 1,603,477,749 cis-eQTLs

92.95% done, 1,605,175,602 cis-eQTLs

92.99% done, 1,605,801,465 cis-eQTLs

92.99% done, 1,606,029,495 cis-eQTLs

93.02% done, 1,606,051,566 cis-eQTLs

93.02% done, 1,606,909,625 cis-eQTLs

93.05% done, 1,608,739,324 cis-eQTLs

93.09% done, 1,609,981,118 cis-eQTLs

93.09% done, 1,610,332,460 cis-eQTLs

93.12% done, 1,610,334,215 cis-eQTLs

93.12% done, 1,611,941,904 cis-eQTLs

93.16% done, 1,613,157,455 cis-eQTLs

93.16% done, 1,613,268,819 cis-eQTLs

93.19% done, 1,613,578,903 cis-eQTLs

93.19% done, 1,614,451,599 cis-eQTLs

93.22% done, 1,615,619,849 cis-eQTLs

93.26% done, 1,616,656,615 cis-eQTLs

93.29% done, 1,617,868,713 cis-eQTLs

93.32% done, 1,619,080,296 cis-eQTLs

93.32% done, 1,619,639,568 cis-eQTLs

93.36% done, 1,619,780,770 cis-eQTLs

93.36% done, 1,621,617,518 cis-eQTLs

93.39% done, 1,623,194,547 cis-eQTLs

93.39% done, 1,623,260,452 cis-eQTLs

93.42% done, 1,623,440,114 cis-eQTLs

93.42% done, 1,623,624,881 cis-eQTLs

93.46% done, 1,623,740,930 cis-eQTLs

93.49% done, 1,623,981,474 cis-eQTLs

93.52% done, 1,624,260,504 cis-eQTLs

93.56% done, 1,624,517,021 cis-eQTLs

93.59% done, 1,624,766,762 cis-eQTLs

93.62% done, 1,624,922,582 cis-eQTLs

93.66% done, 1,625,016,791 cis-eQTLs

93.69% done, 1,625,179,587 cis-eQTLs

93.73% done, 1,625,410,725 cis-eQTLs

93.76% done, 1,625,996,988 cis-eQTLs

93.79% done, 1,626,581,858 cis-eQTLs

93.83% done, 1,626,897,373 cis-eQTLs

93.86% done, 1,627,517,976 cis-eQTLs

93.89% done, 1,628,251,096 cis-eQTLs

93.89% done, 1,628,413,496 cis-eQTLs

93.93% done, 1,628,503,257 cis-eQTLs

93.93% done, 1,629,217,808 cis-eQTLs

93.96% done, 1,630,769,385 cis-eQTLs

93.99% done, 1,632,355,083 cis-eQTLs

93.99% done, 1,632,360,273 cis-eQTLs

94.03% done, 1,632,689,590 cis-eQTLs

94.03% done, 1,633,162,089 cis-eQTLs

94.06% done, 1,634,595,706 cis-eQTLs

94.09% done, 1,636,081,792 cis-eQTLs

94.13% done, 1,636,838,390 cis-eQTLs

94.13% done, 1,637,484,308 cis-eQTLs

94.16% done, 1,637,495,947 cis-eQTLs

94.16% done, 1,638,802,308 cis-eQTLs

94.19% done, 1,639,861,812 cis-eQTLs

94.23% done, 1,640,213,743 cis-eQTLs

94.23% done, 1,640,415,916 cis-eQTLs

94.26% done, 1,640,661,376 cis-eQTLs

94.26% done, 1,641,607,465 cis-eQTLs

94.30% done, 1,642,892,227 cis-eQTLs

94.33% done, 1,644,741,168 cis-eQTLs

94.33% done, 1,644,837,426 cis-eQTLs

94.36% done, 1,645,244,430 cis-eQTLs

94.36% done, 1,646,277,836 cis-eQTLs

94.40% done, 1,647,668,681 cis-eQTLs

94.43% done, 1,649,068,634 cis-eQTLs

94.43% done, 1,649,165,605 cis-eQTLs

94.46% done, 1,649,842,488 cis-eQTLs

94.46% done, 1,651,159,217 cis-eQTLs

94.50% done, 1,653,036,371 cis-eQTLs

94.50% done, 1,653,037,262 cis-eQTLs

94.53% done, 1,654,095,501 cis-eQTLs

94.53% done, 1,654,771,171 cis-eQTLs

94.56% done, 1,654,845,568 cis-eQTLs

94.56% done, 1,656,126,830 cis-eQTLs

94.60% done, 1,657,189,067 cis-eQTLs

94.63% done, 1,657,985,713 cis-eQTLs

94.66% done, 1,658,848,944 cis-eQTLs

94.70% done, 1,660,183,623 cis-eQTLs

94.70% done, 1,660,274,001 cis-eQTLs

94.73% done, 1,661,189,679 cis-eQTLs

94.73% done, 1,661,945,546 cis-eQTLs

94.76% done, 1,662,031,211 cis-eQTLs

94.76% done, 1,663,263,659 cis-eQTLs

94.80% done, 1,665,017,964 cis-eQTLs

94.83% done, 1,666,445,964 cis-eQTLs

94.87% done, 1,667,268,009 cis-eQTLs

94.87% done, 1,667,345,578 cis-eQTLs

94.90% done, 1,667,619,062 cis-eQTLs

94.90% done, 1,668,587,997 cis-eQTLs

94.93% done, 1,670,043,930 cis-eQTLs

94.97% done, 1,670,974,678 cis-eQTLs

95.00% done, 1,671,885,716 cis-eQTLs

95.00% done, 1,671,963,577 cis-eQTLs

95.03% done, 1,672,208,818 cis-eQTLs

95.03% done, 1,672,867,105 cis-eQTLs

95.07% done, 1,674,081,729 cis-eQTLs

95.10% done, 1,675,206,368 cis-eQTLs

95.13% done, 1,675,938,046 cis-eQTLs

95.17% done, 1,676,596,711 cis-eQTLs

95.20% done, 1,677,227,420 cis-eQTLs

95.20% done, 1,677,263,952 cis-eQTLs

95.23% done, 1,677,462,403 cis-eQTLs

95.23% done, 1,677,654,400 cis-eQTLs

95.27% done, 1,677,831,105 cis-eQTLs

95.30% done, 1,678,081,027 cis-eQTLs

95.33% done, 1,678,322,868 cis-eQTLs

95.37% done, 1,678,689,166 cis-eQTLs

95.40% done, 1,679,155,602 cis-eQTLs

95.44% done, 1,679,422,297 cis-eQTLs

95.47% done, 1,679,595,700 cis-eQTLs

95.50% done, 1,679,875,365 cis-eQTLs

95.54% done, 1,680,128,017 cis-eQTLs

95.57% done, 1,680,282,124 cis-eQTLs

95.60% done, 1,680,465,691 cis-eQTLs

95.64% done, 1,680,756,513 cis-eQTLs

95.67% done, 1,681,256,731 cis-eQTLs

95.70% done, 1,682,023,699 cis-eQTLs

95.70% done, 1,682,060,588 cis-eQTLs

95.74% done, 1,682,299,257 cis-eQTLs

95.74% done, 1,682,532,098 cis-eQTLs

95.77% done, 1,683,084,127 cis-eQTLs

95.80% done, 1,683,660,245 cis-eQTLs

95.84% done, 1,684,101,018 cis-eQTLs

95.87% done, 1,684,817,215 cis-eQTLs

95.90% done, 1,685,225,579 cis-eQTLs

95.94% done, 1,685,975,513 cis-eQTLs

95.97% done, 1,686,390,276 cis-eQTLs

95.97% done, 1,686,412,800 cis-eQTLs

96.01% done, 1,687,154,912 cis-eQTLs

96.04% done, 1,688,198,367 cis-eQTLs

96.07% done, 1,689,068,297 cis-eQTLs

96.07% done, 1,689,115,663 cis-eQTLs

96.11% done, 1,689,333,100 cis-eQTLs

96.11% done, 1,690,255,522 cis-eQTLs

96.14% done, 1,691,383,543 cis-eQTLs

96.17% done, 1,692,083,296 cis-eQTLs

96.17% done, 1,692,357,493 cis-eQTLs

96.21% done, 1,692,365,273 cis-eQTLs

96.21% done, 1,692,623,623 cis-eQTLs

96.24% done, 1,693,085,882 cis-eQTLs

96.27% done, 1,693,437,716 cis-eQTLs

96.31% done, 1,693,609,924 cis-eQTLs

96.34% done, 1,694,395,843 cis-eQTLs

96.37% done, 1,695,506,756 cis-eQTLs

96.37% done, 1,695,556,441 cis-eQTLs

96.41% done, 1,695,953,591 cis-eQTLs

96.41% done, 1,697,016,029 cis-eQTLs

96.44% done, 1,698,045,897 cis-eQTLs

96.47% done, 1,698,791,893 cis-eQTLs

96.51% done, 1,699,500,783 cis-eQTLs

96.54% done, 1,700,147,066 cis-eQTLs

96.54% done, 1,700,385,048 cis-eQTLs

96.58% done, 1,700,447,238 cis-eQTLs

96.58% done, 1,701,577,290 cis-eQTLs

96.61% done, 1,702,394,874 cis-eQTLs

96.64% done, 1,702,959,235 cis-eQTLs

96.68% done, 1,703,286,668 cis-eQTLs

96.71% done, 1,703,877,493 cis-eQTLs

96.74% done, 1,704,213,669 cis-eQTLs

96.78% done, 1,704,310,280 cis-eQTLs

96.81% done, 1,704,700,420 cis-eQTLs

96.81% done, 1,704,950,773 cis-eQTLs

96.84% done, 1,705,037,212 cis-eQTLs

96.84% done, 1,706,053,928 cis-eQTLs

96.88% done, 1,707,152,117 cis-eQTLs

96.91% done, 1,708,515,814 cis-eQTLs

96.94% done, 1,709,077,290 cis-eQTLs

96.94% done, 1,709,114,119 cis-eQTLs

96.98% done, 1,709,138,157 cis-eQTLs

96.98% done, 1,709,508,377 cis-eQTLs

97.01% done, 1,710,501,067 cis-eQTLs

97.04% done, 1,712,232,838 cis-eQTLs

97.08% done, 1,714,101,860 cis-eQTLs

97.08% done, 1,714,378,117 cis-eQTLs

97.11% done, 1,715,183,319 cis-eQTLs

97.11% done, 1,716,859,229 cis-eQTLs

97.15% done, 1,716,860,991 cis-eQTLs

97.15% done, 1,717,706,934 cis-eQTLs

97.18% done, 1,717,733,806 cis-eQTLs

97.21% done, 1,717,963,146 cis-eQTLs

97.25% done, 1,718,326,585 cis-eQTLs

97.28% done, 1,718,592,811 cis-eQTLs

97.31% done, 1,718,760,276 cis-eQTLs

97.35% done, 1,719,053,357 cis-eQTLs

97.38% done, 1,719,217,883 cis-eQTLs

97.41% done, 1,719,283,747 cis-eQTLs

97.45% done, 1,719,318,640 cis-eQTLs

97.48% done, 1,719,387,239 cis-eQTLs

97.51% done, 1,719,494,072 cis-eQTLs

97.55% done, 1,719,568,112 cis-eQTLs

97.58% done, 1,719,611,775 cis-eQTLs

97.61% done, 1,719,671,822 cis-eQTLs

97.65% done, 1,719,731,944 cis-eQTLs

97.68% done, 1,719,858,191 cis-eQTLs

97.68% done, 1,719,913,338 cis-eQTLs

97.72% done, 1,719,963,306 cis-eQTLs

97.72% done, 1,720,337,235 cis-eQTLs

97.75% done, 1,720,602,760 cis-eQTLs

97.78% done, 1,720,760,925 cis-eQTLs

97.82% done, 1,720,898,933 cis-eQTLs

97.85% done, 1,721,363,711 cis-eQTLs

97.88% done, 1,721,746,772 cis-eQTLs

97.92% done, 1,722,176,272 cis-eQTLs

97.95% done, 1,722,695,910 cis-eQTLs

97.98% done, 1,723,532,967 cis-eQTLs

98.02% done, 1,724,298,295 cis-eQTLs

98.02% done, 1,724,495,267 cis-eQTLs

98.05% done, 1,724,503,197 cis-eQTLs

98.05% done, 1,725,319,310 cis-eQTLs

98.08% done, 1,725,816,583 cis-eQTLs

98.12% done, 1,726,643,526 cis-eQTLs

98.15% done, 1,727,430,913 cis-eQTLs

98.18% done, 1,728,036,622 cis-eQTLs

98.22% done, 1,728,729,690 cis-eQTLs

98.22% done, 1,728,868,402 cis-eQTLs

98.25% done, 1,729,074,851 cis-eQTLs

98.25% done, 1,729,486,439 cis-eQTLs

98.29% done, 1,729,742,869 cis-eQTLs

98.32% done, 1,730,235,244 cis-eQTLs

98.35% done, 1,731,493,571 cis-eQTLs

98.39% done, 1,733,011,615 cis-eQTLs

98.42% done, 1,734,427,358 cis-eQTLs

98.42% done, 1,734,435,649 cis-eQTLs

98.45% done, 1,735,168,780 cis-eQTLs

98.45% done, 1,735,953,617 cis-eQTLs

98.49% done, 1,735,953,807 cis-eQTLs

98.49% done, 1,737,754,181 cis-eQTLs

98.52% done, 1,739,443,017 cis-eQTLs

98.52% done, 1,739,443,087 cis-eQTLs

98.55% done, 1,740,334,717 cis-eQTLs

98.55% done, 1,741,045,513 cis-eQTLs

98.59% done, 1,741,149,805 cis-eQTLs

98.59% done, 1,742,357,541 cis-eQTLs

98.62% done, 1,742,546,529 cis-eQTLs

98.65% done, 1,743,324,004 cis-eQTLs

98.69% done, 1,744,264,309 cis-eQTLs

98.72% done, 1,745,257,791 cis-eQTLs

98.72% done, 1,745,460,600 cis-eQTLs

98.75% done, 1,745,818,429 cis-eQTLs

98.75% done, 1,746,544,943 cis-eQTLs

98.79% done, 1,747,423,032 cis-eQTLs

98.82% done, 1,748,229,998 cis-eQTLs

98.85% done, 1,748,989,409 cis-eQTLs

98.89% done, 1,749,930,695 cis-eQTLs

98.89% done, 1,749,987,630 cis-eQTLs

98.92% done, 1,750,383,552 cis-eQTLs

98.92% done, 1,750,992,717 cis-eQTLs

98.96% done, 1,751,773,456 cis-eQTLs

98.99% done, 1,752,429,870 cis-eQTLs

99.02% done, 1,753,226,299 cis-eQTLs

99.06% done, 1,753,812,277 cis-eQTLs

99.09% done, 1,754,400,768 cis-eQTLs

99.09% done, 1,754,452,377 cis-eQTLs

99.12% done, 1,754,714,767 cis-eQTLs

99.12% done, 1,755,520,669 cis-eQTLs

99.16% done, 1,756,841,676 cis-eQTLs

99.19% done, 1,757,736,491 cis-eQTLs

99.22% done, 1,758,420,155 cis-eQTLs

99.26% done, 1,758,756,609 cis-eQTLs

99.26% done, 1,758,790,601 cis-eQTLs

99.29% done, 1,758,859,715 cis-eQTLs

99.29% done, 1,758,954,934 cis-eQTLs

99.32% done, 1,759,320,328 cis-eQTLs

99.36% done, 1,760,122,166 cis-eQTLs

99.39% done, 1,761,329,274 cis-eQTLs

99.42% done, 1,762,946,508 cis-eQTLs

99.43% done, 1,762,983,451 cis-eQTLs

99.46% done, 1,763,358,466 cis-eQTLs

99.46% done, 1,764,467,297 cis-eQTLs

99.49% done, 1,765,718,113 cis-eQTLs

99.53% done, 1,766,544,035 cis-eQTLs

99.53% done, 1,766,727,183 cis-eQTLs

99.56% done, 1,766,804,429 cis-eQTLs

99.56% done, 1,768,082,236 cis-eQTLs

99.59% done, 1,769,434,945 cis-eQTLs

99.63% done, 1,770,413,209 cis-eQTLs

99.66% done, 1,771,349,980 cis-eQTLs

99.66% done, 1,771,409,535 cis-eQTLs

99.69% done, 1,771,914,723 cis-eQTLs

99.69% done, 1,772,554,953 cis-eQTLs

99.73% done, 1,772,588,279 cis-eQTLs

99.73% done, 1,773,791,003 cis-eQTLs

99.76% done, 1,775,320,356 cis-eQTLs

99.79% done, 1,776,258,748 cis-eQTLs

99.83% done, 1,776,697,866 cis-eQTLs

99.86% done, 1,777,345,779 cis-eQTLs

99.86% done, 1,777,440,691 cis-eQTLs

99.89% done, 1,777,904,153 cis-eQTLs

99.89% done, 1,778,306,374 cis-eQTLs

99.93% done, 1,778,400,048 cis-eQTLs

99.93% done, 1,779,214,596 cis-eQTLs

99.96% done, 1,780,724,341 cis-eQTLs

100.00% done, 1,782,563,169 cis-eQTLs

Task finished in 6736.082 seconds



In [35]:
plot(mqtls)
In [4]:
mqtl_hits <- fread("cis_mQTL_IRN_hits.tsv")
#mqtl_hits <- mqtls$cis$eqtls

# --- Quick summary
cat("Number of cis hits:", nrow(mqtl_hits), "\n")
head(mqtl_hits)
Number of cis hits: 1782563169 
A data.table: 6 × 6
SNPgenebetat-statp-valueFDR
<chr><chr><dbl><dbl><dbl><dbl>
rs35682 cg11030744-1.174092-23.836563.935307e-481.143718e-39
rs35681 cg11030744-1.174092-23.836563.935307e-481.143718e-39
rs7120471cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7930916cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7930212cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7931369cg07136909-1.244506-23.634329.369143e-481.143718e-39
In [5]:
sig_mqtls <-mqtl_hits %>%
filter(FDR	 < 0.05) %>%
  arrange(FDR)

length(unique(sig_mqtls$gene))
dim(sig_mqtls)
head(sig_mqtls)
121492
  1. 6016742
  2. 6
A data.table: 6 × 6
SNPgenebetat-statp-valueFDR
<chr><chr><dbl><dbl><dbl><dbl>
rs35682 cg11030744-1.174092-23.836563.935307e-481.143718e-39
rs35681 cg11030744-1.174092-23.836563.935307e-481.143718e-39
rs7120471cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7930916cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7930212cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7931369cg07136909-1.244506-23.634329.369143e-481.143718e-39
In [6]:
write.table(sig_mqtls, file = "sig_mqtls_FDR_0.05.tsv", sep = "\t", quote = FALSE, row.names = FALSE)
In [40]:
# Bonferroni-corrected multiple-testing threshold calculated by dividing the genome-wide significance threshold for GWAS (5×10 −8) by the number of DNAm sites tested
bonferroni_threshold <- 5e-8 / nrow(beta_int)

sig_mqtls_bonf <- mqtl_hits %>%
filter(pvalue < bonferroni_threshold) %>%
  arrange(pvalue)

dim(sig_mqtls_bonf)
head(sig_mqtls_bonf)
  1. 467883
  2. 6
A data.frame: 6 × 6
snpsgenestatisticpvalueFDRbeta
<chr><chr><dbl><dbl><dbl><dbl>
1rs35682 cg11030744-23.836563.935307e-481.143718e-39-1.174092
2rs35681 cg11030744-23.836563.935307e-481.143718e-39-1.174092
3rs7120471cg07136909-23.634329.369143e-481.143718e-39-1.244506
4rs7930916cg07136909-23.634329.369143e-481.143718e-39-1.244506
5rs7930212cg07136909-23.634329.369143e-481.143718e-39-1.244506
6rs7931369cg07136909-23.634329.369143e-481.143718e-39-1.244506
In [38]:
observed <- -log10(sort(sig_mqtls$FDR))
expected <- -log10(ppoints(length(sig_mqtls$FDR)))

qq_df <- data.frame(Expected = expected, Observed = observed)

ggplot(qq_df, aes(x = Expected, y = Observed)) +
  geom_point(alpha = 0.5) +
  geom_abline(slope = 1, intercept = 0, color = "red") +
  labs(x = "Expected -log10(FDR)", y = "Observed -log10(FDR)") +
  theme_minimal()
In [11]:
head(sig_mqtls)
A data.table: 6 × 6
SNPgenebetat-statp-valueFDR
<chr><chr><dbl><dbl><dbl><dbl>
rs35682 cg11030744-1.174092-23.836563.935307e-481.143718e-39
rs35681 cg11030744-1.174092-23.836563.935307e-481.143718e-39
rs7120471cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7930916cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7930212cg07136909-1.244506-23.634329.369143e-481.143718e-39
rs7931369cg07136909-1.244506-23.634329.369143e-481.143718e-39
In [ ]:
hits_pos <- merge(
  sig_mqtls,
  snpspos,
  by.x = "SNP",
  by.y = "id",
  all.x = FALSE
)
In [14]:
head(hits_pos)
dim(hits_pos)
A data.table: 6 × 8
SNPgenebetat-statp-valueFDRChromosomePosition
<chr><chr><dbl><dbl><dbl><dbl><int><int>
rs1000000 cg07890862 0.6132117 4.3966982.336726e-051.038600e-0212126890980
rs1000000 cg27500229 0.5696887 4.0771878.088021e-052.828186e-0212126890980
rs10000003cg00493422 0.7288318 5.7206927.509461e-087.486246e-05 4 57561647
rs10000012cg19621877-0.9828417-5.8242434.626602e-084.874085e-05 4 1357325
rs10000012cg02988312-0.9475813-5.6361291.111471e-071.058248e-04 4 1357325
rs10000012cg12109141 0.8840186 5.0814221.341492e-069.302401e-04 4 1357325
  1. 6016742
  2. 8
In [51]:
library(qqman)

# Convert chromosomes to numeric
mqtl_manhattan <- hits_pos %>%
  mutate(CHR = case_when(
    Chromosome == "X" ~ 23,
    Chromosome == "Y" ~ 24,
    TRUE ~ as.numeric(as.character(Chromosome))
  )) %>%
  rename(
    BP = Position,
    P = `p-value`,
    SNP = SNP
  )


manhattan(
  mqtl_manhattan,
  chr = "CHR",
  bp  = "BP",
  p   = "P",
  snp = "SNP",
  col = c("skyblue", "slateblue"),
  ylim = c(0, 15),
  main = "mQTL Manhattan Plot"
)

mtext("All points shown: FDR < 0.05", side = 3, line = 0.5, cex = 0.9)
In [25]:
head(hits_pos )
A data.table: 6 × 8
SNPgenebetat-statp-valueFDRChromosomePosition
<chr><chr><dbl><dbl><dbl><dbl><int><int>
rs1000000 cg07890862 0.6132117 4.3966982.336726e-051.038600e-0212126890980
rs1000000 cg27500229 0.5696887 4.0771878.088021e-052.828186e-0212126890980
rs10000003cg00493422 0.7288318 5.7206927.509461e-087.486246e-05 4 57561647
rs10000012cg19621877-0.9828417-5.8242434.626602e-084.874085e-05 4 1357325
rs10000012cg02988312-0.9475813-5.6361291.111471e-071.058248e-04 4 1357325
rs10000012cg12109141 0.8840186 5.0814221.341492e-069.302401e-04 4 1357325
In [57]:
head(geno_M)
head(beta_int)
head(top_hits)
A data.frame: 6 × 130
ID0022ID0262ID0393ID0439ID0479ID0494ID0511ID0824ID0879ID1075⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
<int><int><int><int><int><int><int><int><int><int>⋯<int><int><int><int><int><int><int><int><int><int>
rs5752721510000000100⋯0000010011
rs5444190190000000100⋯0000010011
rs626352860001010010⋯0100000010
rs2005799490001010010⋯0100000010
rs5317308561100000000⋯1000001000
rs5461694440000000100⋯0001000001
A matrix: 6 × 130 of type dbl
ID0022ID0262ID0393ID0439ID0479ID0494ID0511ID0824ID0879ID1075⋯ID9428ID9459ID9604ID9611ID9621ID9663ID9720ID9781ID9918ID9972
cg18478105-1.06696313 2.2421448-0.04813044 0.9699855-0.85333404-0.14484044 0.1838557-0.825955784-0.086709895 1.71485202⋯-1.0012651 0.7472802 0.8259558-0.06740763 0.4904714 0.55669604 0.7220731 0.4053494 0.067407627 1.50455851
cg14361672-0.04813044 1.2557323-0.79918308-0.1838557 0.67298051 0.02887113-0.2034650-1.345378982 0.772971331-0.08670989⋯ 0.2627979 0.4688799-0.4475049 0.82595578-0.3028605-0.12541888 0.6022241 0.4263324 0.556696037 0.04813044
cg01763666 0.44750489-0.6729805-0.60222414 0.6022241-1.91367115-1.21447042-1.5045585 0.009622522 0.772971331-1.39456256⋯ 0.9396272-0.1060445-0.3230715 0.16431679 1.9136711 0.06740763 1.7148520 0.6973167-0.223152902 0.12541888
cg12950382-0.46887992 2.5900238-0.62545898 1.9136711 0.06740763-0.77297133-0.5793100-0.028871131 0.009622522 0.26279793⋯-0.7472802 0.6022241 2.2421448 0.42633241-0.5343633 0.72207313 0.4904714 0.2231529 2.050587838-0.79918308
cg02115394-1.91367115 0.3434154 1.91367115-0.1254189 1.21447042-0.14484044-1.5671376 0.144840440 0.534363291 0.42633241⋯-0.7991831-1.8053670-0.8533340 0.51229395 0.8533340-1.63653605-0.8813674-2.5900238-0.009622522 0.28277249
cg13417420-1.00126511 0.2627979 1.56713759-1.2144704-0.60222414 1.06696313 0.7729713-2.242144800 0.747280213 0.91011111⋯-0.6729805-0.4263324 0.3434154 0.16431679-1.1376221 0.38454329 0.4263324 1.0012651 0.106044526-0.62545898
A data.table: 5 × 8
SNPgenebetat-statp-valueFDRChromosomePosition
<chr><chr><dbl><dbl><dbl><dbl><int><int>
rs35681 cg11030744-1.174092-23.836563.935307e-481.143718e-39 3 10329377
rs7120471 cg07136909-1.244506-23.634329.369143e-481.143718e-3911 71277598
rs11548102cg08477332 1.177868 23.568981.241261e-471.143718e-39 1153587256
rs12366241cg14262357-1.159907-23.542801.389551e-471.143718e-3911102424628
rs8110698 cg24245216-1.253027-23.470451.898813e-471.143718e-3919 7004532
In [65]:
top_hits <- hits_pos %>%
  arrange(`p-value`) %>%
  distinct( gene, .keep_all = TRUE) %>%
  head(5)

samps <- intersect(colnames(geno_M), colnames(beta_int))

for (i in seq_len(nrow(top_hits))) {
  snp      <- top_hits$SNP[i]
  cpg      <- top_hits$gene[i]
  beta_eff <- round(top_hits$beta[i], 2)

  gvec <- as.numeric(geno_M[snp, samps])
  mvec <- as.numeric(beta_int[cpg, samps])

  df <- data.frame(
    Genotype    = factor(gvec, levels = c(0,1,2), labels = c("0","1","2")),
    Methylation = mvec
  )
  df <- df[complete.cases(df), ]

  # Ensure all levels are present
  counts <- table(factor(df$Genotype, levels = c("0","1","2")))
  x_labs <- paste0(levels(df$Genotype), " (n=", as.integer(counts), ")")

  # Skip plotting if all counts are zero
  if (sum(counts) == 0) next

  p <- ggplot(df, aes(x = Genotype, y = Methylation, fill = Genotype)) +
    geom_boxplot(alpha = 0.85, outlier.shape = NA, color = "black") +
    geom_jitter(width = 0.2, alpha = 0.6) +
    scale_fill_manual(values = c("0"="#b0c4de", "1"="#4682b4", "2"="#0b3d91")) +
    scale_x_discrete(drop = FALSE, labels = x_labs) +
    labs(
      title = paste("Top mQTL:", cpg, "vs", snp, "| β =", beta_eff),
      x = "Genotype (0/1/2)",
      y = "Methylation (B-values)"
    ) +
    theme_minimal(base_size = 13) +
    theme(legend.position = "none")

  print(p)
}