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["Metadata","Values"]
[]
["Asset Title ","Glucose Pulsed L. Lactis 160709"]
["Uploader","Martijn Bekker"]
["Uploader SEEK ID",53]
["Project","sysmolab"]
[]
["ASSAY"]
["Assay SEEK ID",27]
["Assay Title","Glucose pulsed L. lactis"]
["Assay_type","Glucose pulse"]
["Technology_type","HPLC"]
["Description","Glucose pulsed cells for analysis of changes of the metabolome"]
["Experimentalist","Martijn Bekker"]
["Date","2010-01-08"]
["SOP ID",84]
["SOP Description","SOP7 Glucose Pulse Experiments"]
[]
["Experimental_conditions"]
["Item","temperature","pH","Gas Flow","volume"]
["Compound (if concentration)"]
["Unit","ºC","dimensionless","ml/min","ml"]
["Start_value (optional)",37,6.5,"±400",20]
["End_value (optional)"]
["Comments"]
[]
["FACTORS_STUDIED"]
["Item","concentration"]
["Compound (if concentration)","Glucose"]
["Unit","mM"]
["Start_value (optional)",0]
["End_value (optional)",20]
["SD (optional)"]
["Comments","Cultures were pulsed with 20 mM glucose"]

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[2,"Lactococus Lactis",1358,"NZ9000","Wild-type","Wild-type","Whole Cell",20,600,"2010-01-08","2010-02-08",24]
[3,"Lactococus Lactis",1358,"NZ9000","Wild-type","Wild-type","Whole Cell",50,600,"2010-01-08","2010-02-08",24]

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["<http://www.mygrid.org.uk/ontology/JERMOntology#2-hybrid_system>","2-hybrid_system"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#2D_gel_electrophoresis>","2D_gel_electrophoresis"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#Accelerator_Mass_Spectrometry>","Accelerator_Mass_Spectrometry"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#affinity_chromatography>","affinity_chromatography"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#Batch>","Batch"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#Chemostat>","Chemostat"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#chemostat_measurements>","chemostat_measurements"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#ChIP-on-chip>","ChIP-on-chip"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#chromatography>","chromatography"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#CultureGrowth>","CultureGrowth"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#custom_Array>","custom_Array"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#DNA_Methylation>","DNA_Methylation"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#electrophoresis>","electrophoresis"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#FACS>","FACS"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#gas_chromatography>","gas_chromatography"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#gel_electrophoresis>","gel_electrophoresis"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#gel_filtration>","gel_filtration"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#HPLC>","HPLC"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#imaging>","imaging"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#Intracellular_Metabolite_Concentration>","Intracellular_Metabolite_Concentration"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#metabolite_profiling>","metabolite_profiling"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#metabolomics>","metabolomics"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#methylation_profiling>","methylation_profiling"]
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["<http://www.mygrid.org.uk/ontology/JERMOntology#primer_design>","primer_design"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#protein-protein_interaction>","protein-protein_interaction"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#protein-protein_interaction_profiling>","protein-protein_interaction_profiling"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#protein_expression_profiling>","protein_expression_profiling"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#protein_identification>","protein_identification"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#protein_purification>","protein_purification"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#protein_structural_analysis>","protein_structural_analysis"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#proteomics>","proteomics"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#reactomics>","reactomics"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#RNAi>","RNAi"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#single_cell>","single_cell"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#small-molecule_microarray>","small-molecule_microarray"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#SNP_detection>","SNP_detection"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#Substrate_utilization>","Substrate_utilization"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#tiling_path>","tiling_path"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#transcripomics>","transcripomics"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#transcriptional_profiling>","transcriptional_profiling"]
["<http://www.mygrid.org.uk/ontology/JERMOntology#translational_profiling>","translational_profiling"]

{"sheet":"Data_Internal_Metabolites","index":9,"n_rows":52,"n_cols":17,"rows_kept":52,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Sample ID","Metabolite","Unit"]
[null,"Time after glucose-pulse","min",-0.1,5,10,15,20,25,30,40,50,60,75,90,null,"Maximal value"]
[]
[1,"FBP","mM",-0.6330321965262318,4.838174644878831,1.5825804913155048,-0.6330321965262025,-1.4921473203831903,-1.1756312221201037,0.6330321965262025,0.4069492691954153,-2.667778542503279,-2.848644884367893,-0.9947648802554747,null,null,4.838174644878831]
[2,"FBP","mM",0.21217013180270428,26.591989852609814,18.3880780895706,5.799316935941485,3.53616886337894,0.3536168863378979,2.7582117134356157,0.35361688633789967,0.5657870181406377,-0.9194039044785054,0.21217013180273803,4.031232504252015,null,26.591989852609814]
[3,"FBP","mM",2.364181468659109,14.97314930150751,17.271659062703833,5.647766841796667,0.853732197015777,3.5462722029885887,2.4955248835845882,1.444777564180578,-1.6417926865688282,-0.13134341492548174,3.4806004955258665,0.853732197015777,null,17.271659062703833]
[{"$nulls":16},0]
[]
[1,"G6P","mM",0.8669074742984143,2.2006112809113656,1.2003334259516532,1.3559322033898327,1.6226729647124203,1.3114754098360657,-0.5334815226451799,-1.2892470130591818,-0.4223395387607676,-1.1558766323978884,-1.022506251736594,-0.22228396776882575,null,2.2006112809113656]
[2,"G6P","mM",0.2433724467622791,2.3641894828335523,2.6075619295958288,3.0943068231203834,0.45197740112994345,-3.9982616253802696,-0.3129074315514964,0.3129074315514964,0.451977401129943,0.38244241634072196,-0.6953498478922209,-0.5215123859191632,null,3.0943068231203834]
[3,"G6P","mM",-0.5488297013720735,2.905569007263921,3.5512510088781273,0.09685230024212936,1.3559322033898296,0.6779661016949166,-0.1614205004035536,-0.45197740112994544,-0.9039548022598879,-4.810330912025827,-0.6779661016949143,0.8071025020177538,null,3.5512510088781273]
[{"$nulls":16},0]
[]
[1,"F6P","mM",-0.27196494674019794,0.3324016015713513,-0.15109163707788775,-0.21152829190904326,-0.332401601571353,-0.24174661932462171,0.6648032031427069,-0.33240160157135346,0.39283825640250813,-0.7554581853894383,0,-0.1813099644934653,null,0.6648032031427069]
[2,"F6P","mM",-0.09452912678719268,1.0398203946591045,-0.9452912678719133,-0.5671747607231491,-0.2835873803615716,0.04726456339359286,-0.04726456339359697,-1.796053408956632,-1.0398203946591065,-0.614439324116745,-0.7562330142975311,-0.99255583126551,null,1.0398203946591045]
[3,"F6P","mM",3.1363800445660672e-15,-0.08777704630238947,0.4388852315119627,-0.6144393241167436,-0.3072196620583667,-1.097213078779899,-0.17555409260478005,-0.08777704630238992,0.43888523151195646,4.0377441299100285,0.8338819398727226,0.9216589861751159,null,4.0377441299100285]
[{"$nulls":16},0]
[]
[1,"ATP","mM",-0.08885334754986801,2.2035630192367504,0.5864320938291351,0.1954773646097109,-0.035541339019946855,1.0269562977782698e-15,-0.1599360255897651,0.24878937313963304,-0.07108267803989518,0.19547736460971196,0.08885334754986896,0.5153494157892397,null,2.2035630192367504]
[2,"ATP","mM",0.027100271002709952,0.2168021680216794,0.027100271002709952,0.46070460704606925,0.13550135501355004,0.3794037940379419,0.5691056910569109,0.2981029810298087,0.46070460704606925,0.29810298102981025,0.1897018970189709,0.3252032520325191,null,0.5691056910569109]
[3,"ATP","mM",0,3.3552716479545737,4.852238998580461,0.6710543295909153,-0.4129565105174862,0.20647825525874414,0.1290489095367126,0.20647825525874236,0.12904890953671627,-0.980771712479029,-1.2388695315524594,0.20647825525874236,null,4.852238998580461]
[{"$nulls":16},0]
[]
[1,"PYR","mM",-1.0399814657216333,2.5321287861048094,0.8365068311239203,-0.8365068311239097,-2.1025712241763235,-2.6677785425032874,-0.7234653674585352,-0.7234653674585063,-5.199907328608086,-2.80342829890175,-2.893861469834072,10.535464413614644,null,10.535464413614644]
[2,"PYR","mM",1.6973610544218989,17.18578067602177,13.366718303572478,8.48680527210951,6.329742265448335,3.500807174745181,5.056721474631938,4.844551342829188,1.5205526112529588,3.3593604202100247,1.7680844316894815,5.268891606434659,null,17.18578067602177]
[3,"PYR","mM",2.1343304925394615,12.379116856728796,14.710462471656495,8.011948310455761,5.056721474631932,7.5194105044851,6.205976355230077,4.728362937318187,2.331345614927684,1.7403002477629457,6.0417970865732045,8.63582953135193,null,14.710462471656495]
[{"$nulls":16},0]
[]
[1,"PEP","mM",{"$nulls":13},0]
[2,"PEP","mM",{"$nulls":13},0]
[3,"PEP","mM",{"$nulls":13},0]
[{"$nulls":16},0]
[]
[1,"2PGA","mM",{"$nulls":13},0]
[2,"2PGA","mM",{"$nulls":13},0]
[3,"2PGA","mM",{"$nulls":13},0]
[{"$nulls":16},0]
[]
[1,"PYR","mM",{"$nulls":13},0]
[2,"PYR","mM",{"$nulls":13},0]
[3,"PYR","mM",{"$nulls":13},0]
[{"$nulls":16},0]
[]
[1,"ADP","mM",1.952957947255874,5.75908766928011,2.637205987170344,1.2829650748396244,2.2095509622238065,-1.3257305773342871,1.02637205987171,2.6229508196721354,2.22380612972203,0.7270135424091312,2.0812544547398413,3.2786885245901716,null,5.75908766928011]
[2,"ADP","mM",3.344481605351157,3.500557413600882,0.6688963210702341,2.9654403567446974,2.987736900780379,9.364548494983278,6.845039018952063,3.143812709030101,5.195094760312154,7.959866220735777,2.1627647714604237,5.0836120401337705,null,9.364548494983278]
[3,"ADP","mM",5.610766045548661,2.5465838509316816,3.7681159420289805,2.7950310559006213,2.2981366459627224,-2.567287784679081,2.629399585921343,4.202898550724631,2.3395445134575685,5.879917184265008,4.327122153209103,3.209109730848861,null,5.879917184265008]
[{"$nulls":16},0]
[]
[1,"AMP","mM",10.36429872495447,1.948998178506376,6.812386156648452,12.659380692167577,10.400728597449909,14.40801457194899,9.289617486338798,5.44626593806922,7.850637522768658,7.304189435336976,6.75774134790529,10.910746812386153,null,14.40801457194899]
[2,"AMP","mM",15.128205128205138,4.6723646723646715,8.575498575498576,19.6011396011396,23.36182336182337,11.054131054131055,9.316239316239306,21.680911680911677,13.504273504273492,15.584045584045617,11.994301994301992,6.239316239316249,null,23.36182336182337]
[3,"AMP","mM",11.111111111111112,3.227513227513218,4.920634920634919,12.037037037037027,12.645502645502646,14.523809523809526,11.03174603174602,12.777777777777764,9.074074074074073,11.428571428571429,11.005291005291005,12.989417989418001,null,14.523809523809526]
[{"$nulls":16},0]

{"sheet":"Data_External_Metabolites","index":10,"n_rows":13,"n_cols":15,"rows_kept":13,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Sample","Metabolite","Unit"]
["Time",null,"min",-0.1,5,10,15,20,25,30,40,50,60,75,90]
[1,"Glucose","mM",10,3.1673,0,0,0,0,0,0,0,0,0,0]
[1,"Lactate","mM",0,4.391600000000004,12.384900000000002,12.150300000000001,15.815200000000004,null,15.419600000000003,null,11.828800000000001,16.846199999999996,21.140299999999996,16.3536]
[1,"Phosphate","mM",0,0,0,0,0,0,0,0,0,0,0,0]
[]
[2,"Glucose","mM",10,5.2049,0,0,0,0,0,0,0,0,0,0]
[2,"Lactate","mM",0,7.165,8.060200000000002,9.824800000000003,6.4011,6.074600000000004,6.684199999999997,5.9739,13.957100000000004,6.279600000000002,3.5630999999999986,19.9185]
[2,"Phosphate","mM",26.0814,25.3482,25.6658,25.7127,13.4011,26.4661,26.4543,26.6929,27.3312,27.8113,29.7022,31.3758]
[]
[3,"Glucose","mM",10,7.1663,0.5527,null,0,0,0,0,0,0,0]
[3,"Lactate","mM",0,8.411099999999998,20.214699999999993,null,9.627299999999998,13.021499999999996,24.043099999999995,15.4454,41.0874,27.978899999999996,23.6879]
[3,"Phosphate","mM",59.7713,58.73,59.2027,null,61.0145,60.316,60.9411,62.391,63.3986,66.0839,72.052]