NHP Tissue Collection – Metadata
SEEK ID: https://fairdomhub.org/assays/1918
Experimental Assay
Projects: IMPAcTB
Investigation: hidden item
Assay position:
Assay type: Experimental Assay Type
Technology type: Technology Type
Organisms: No organisms
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Creators and SubmitterViews: 57
Created: 20th May 2022 at 19:43
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Institutions: Massachusetts Institute of Technology
Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology
Projects: IMPAcTB
Web page: https://www.niaid.nih.gov/research/immune-mechanisms-protection-mycobacterium-tuberculosis
Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the granuloma. In some granulomas, immune activity promotes bacterial clearance, but in others, bacteria persist and grow. We identified correlates of bacterial control in cynomolgus macaque lung granulomas by co-registering longitudinal positron emission tomography and computed tomography imaging, single-cell RNA sequencing, and measures of bacterial clearance. Bacterial persistence occurred in granulomas ...
Submitter: Dikshant Pradhan
Investigation: 1 hidden item
Assays: DNA Extraction – Metadata, NHP Tissue Collection – Metadata, Single Cell Sequencing – Metadata
