Projects
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Despite the intensive use of agrochemicals, plant pathogens are responsible for huge yield losses worldwide. Understanding the interaction between plant and pathogens is crucial to ensure long lasting and environmentally friendly system of plant protection. Therefore research of the most important human food crops in combination with their pathogens is one of the highest priorities for sustainable agriculture.
The aim of the proposed research project is to bring new perspective into understanding ...
Programme: NIBSys
Public web page: http://projects.nib.si/hyp/
The project “Rational development of anti-cancer combinations” focuses on precision medicine for cancer by pursuing novel insight into cancer disease mechanisms, combinatorial drug treatment in order to enable selection of the best treatment for the individual patient. The aim is to develop and integrate computational, experimental and analytical approaches to predict and validate anti-cancer drug combinations and produce an integrated pipeline for rational screening of synergistic drugs and for ...
Programme: Druglogics
Public web page: https://www.ntnu.edu/health/druglogics
In the project “Crossover Research 2.0 – Well constructed Knowledge Commons” the domain of precision medicine is explored as a key visionary driver for developing the Knowledge Commons and the enabling of Systems Biology approaches to innovate healthcare. In particular, we seek to engage stakeholder concerns in investigating and establishing strategies for DrugLogics to contribute to the Knowledge Commons in an RRI mode.
Programme: Druglogics
Public web page: http://www.ntnu.edu/crossover-research
Short-chain fatty-acids (SCFA) are produced from dietary fibres by the intestinal microbiota. They protect humans against obesity. The fate of SCFA and their impact on human fat metabolism is complex and dynamic. To optimally apply prebiotic (fibre) and probiotic (microbial) supplements, a better understanding of their mode of action is required. Our aim is to construct, infer, and analyse a dynamic, multiscale computational model predicting how dietary fibres affect the balance between fat intake ...
Programme: Independent Projects
Public web page: https://www.nwo.nl/en/research-and-results/research-projects/i/75/29175.html
SAFE-Aqua (SustainAble Farming for Effective Aquaculture) is an international consortium research project, consisting of a group of multidisciplinary experts from leading research institutes in France, UK, Thailand and a private-company in Spain.
Programme: SAFE-Aqua
Public web page: http://safeaqua-project.net
Programme: Mathematical modelling of the morphological transition of Pseudomonas aeruginosa
Public web page: Not specified
EPSRC project with Exeter, SynthSys and EPCC
Programme: SynthSys
Public web page: Not specified
EU FP7 collaborative project TiMet, award number 245143. Funded 2010-2015. "TiMet assembles world leaders in experimental and theoretical plant systems biology to advance understanding of the regulatory interactions between the circadian clock and plant metabolism, and their emergent effects on whole-plant growth and productivity."
Programme: SynthSys
Public web page: http://timing-metabolism.eu/
Programme: LiSyM - Systems Medicine of the Liver
Public web page: https://www.fairdomhub.org/events/96
Public showcase and collection of training material
Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: http://www.denbi.de
Pesticides, plastics, cosmetics, electrical transformers and many other products contain Endocrine disruptors (EDCs). EDCs interfere with natural hormone functions and may cause the disease.
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
WURSynBio
Programme: This Project is not associated with a Programme
Public web page: Not specified
Escherichia coli is a well-established and the most widely used organism for the production of recombinant proteins (used in medical and industrial applications, as molecular biology reagents, etc.). Production of proteins is the most resource exhaustive process for the cells and therefore needs to be optimized to achieve maximal productivities. Natural environment of E. coli is much harsher compared to the near optimal growth conditions used in production processes. In order to survive cells ...
Programme: ERASysAPP
Public web page: https://www.bioprocess.tu-berlin.de/menue/research/projects/leanprot/
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Programme: Druglogics
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
CropClock - Increasing Crops Biomass by Uncovering the Circadian Clock Network Using Dynamical Models
The circadian clock is an internal timing system that allows plants to predict daily and seasonal changes in light and temperature and thus to adapt photosynthesis, growth, and development to external conditions. The core oscillator is well understood in the model plant Arabidopsis, however, relatively little is known about the dynamic effects of the clock on agronomic behaviour of crop plants. ...
Programme: ERASysAPP
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Cystic Fibrosis (CF)- lethal autosomic disease CFTR - Cystic Fibrosis Transmembrane Regulator
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
We are modelling ROS management and mitochondrial dysfunction. Mitochondria produce both energy and reactive oxygen species (ROS), and suffer from ROS. Experimental data from University Milan-Bicocca.
Programme: Model repository for M4 (Make Me My Model) clients of ISBE
Public web page: Not specified
Programme: This Project is not associated with a Programme
Public web page: Not specified
This project provides a space for storing, annotating and publishing Systo models.
Programme: Independent Projects
Public web page: Not specified
Within the e:Bio - Innovationswettbewerb Systembiologie (Federal Ministry of Education and Research (BMBF)), the SulfoSYSBIOTECH consortium (10 partners), aim to unravel the complexity and regulation of the carbon metabolic network of the thermoacidophilic archaeon Sulfolobus solfataricus (optimal growth at 80°C and pH 3) in order to provide new catalysts ‘extremozymes’ for utilization in White Biotechnology.
Based on the available S. solfataricus genome scale metabolic model (Ulas et al., 2012) ...
Programme: e:Bio
Public web page: http://www.sulfosys.com/
GMO free systems optimization of wine yeast for wine production by massive scale directed evolution
Programme: ERASysAPP
Public web page: Not specified
Designer microbial communities for fermented milk products: A Systems Biology Approach
Programme: ERASysAPP
Public web page: Not specified
ErasysApp Funders
Programme: ERASysAPP
Public web page: Not specified